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 Forschungsbericht für das Jahr 2017

Department für Pathologie

Institut für Klinische Pathologie

Breisacher Str. 115a
79106 Freiburg
Tel: ( +49) 0761 / 270-8006 Fax: ( +49) 0761 / 270-8004
Email direktion-pathologie@uniklinik-freiburg.de
http://www.uniklinik-freiburg.de/pathologie/live/index.html


Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Ahrens TD, Lutz L, Lassmann S, Werner M: Turning Skyscrapers into Town Houses: Insights into Barrett's Esophagus. Pathobiology, 2017; 84 (2): 87-98. : http://dx.doi.org/10.1159/000447779
  • Andrlova H, Mastroianni J, Madl J, Kern JS, Melchinger W, Dierbach H, Wernet F, Follo M, Technau-Hafsi K, Has C, Rao Mittapalli V, Idzko M, Herr R, Brummer T, Ungefroren H, Busch H, Boerries M, Narr A, Ihorst G, Vennin C, Schmitt-Graeff A, Minguet S, Timpson P, Duyster J, Meiss F, Romer W, Zeiser R: Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-beta1 expression. Oncotarget, 2017; 8 (26): 42901-42916. : http://dx.doi.org/10.18632/oncotarget.17160
  • Breitenbuecher F, von Pawel J, Sebastian M, Kortsik C, Ting S, Kasper S, Wohlschlager J, Worm K, Morresi-Hauf A, Schad A, Westerwick D, Wehler B, Werner M, Munzert G, Gaschler-Markefski B, Schmid KW, Schuler M: Comprehensive Biomarker Analyses in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer Prospectively Treated with the Polo-Like Kinase 1 Inhibitor BI2536. Oncol Res Treat, 2017; 40 (7-8): 435-439. : http://dx.doi.org/10.1159/000475503
  • Bure I, Braun A, Kayser C, Geddert H, Schaefer IM, Cameron S, Ghadimi MB, Strobel P, Werner M, Hartmann A, Wiemann S, Agaimy A, Haller F, Moskalev EA: The expression of hematopoietic progenitor cell antigen CD34 is regulated by DNA methylation in a site-dependent manner in gastrointestinal stromal tumours. Int J Cancer, 2017; 141 (11): 2296-2304. : http://dx.doi.org/10.1002/ijc.30905
  • Czulkies BA, Mastroianni J, Lutz L, Lang S, Schwan C, Schmidt G, Lassmann S, Zeiser R, Aktories K, Papatheodorou P: Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells. Oncotarget, 2017; 8 (23): 37009-37022. : http://dx.doi.org/10.18632/oncotarget.10425
  • Dimmler A, Geddert H, Werner M, Faller G: Molecular analysis of BRAF V600E mutation in multiple nodules of pulmonary Langerhans cell histiocytosis. Virchows Arch, 2017; 470 (4): 429-435. : http://dx.doi.org/10.1007/s00428-017-2092-4
  • Dornhof R, Maschowski C, Osipova A, Giere R, Seidl M, Merfort I, Humar M: Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion. Plos One, 2017; 12 (7) (online): e0180291-e0180291. : http://dx.doi.org/10.1371/journal.pone.0180291
  • Enderle-Ammour K, Bader M, Ahrens TD, Franke K, Timme S, Csanadi A, Hoeppner J, Kulemann B, Maurer J, Reiss P, Schilling O, Keck T, Brabletz T, Stickeler E, Werner M, Wellner UF, Bronsert P: Form follows function: Morphological and immunohistological insights into epithelial-mesenchymal transition characteristics of tumor buds. Tumor Biol, 2017; 39 (5) (online): 1010428317705501-1010428317705501. : http://dx.doi.org/10.1177/1010428317705501
  • Fauth L, Boettler T, Werner M: Präkanzerosen von Ösophagus, Magen und Kolon Onkologe, 2017; 23 (10): 861-870.
  • Fichter CD, Przypadlo CM, Buck A, Herbener N, Riedel B, Schafer L, Nakagawa H, Walch A, Reinheckel T, Werner M, Lassmann S: A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion. J Pathol, 2017; 243 (4): 481-495. : http://dx.doi.org/10.1002/path.4987
  • Fuellgraf H, Schilling O, Lai ZW, Kulemann B, Timme S, Makowiec F, Shahinian JH, Hoeppner J, Werner M, Hopt UT, Wellner UF, Bronsert P: The Prognostic Impact of the Carcinoembryonic Antigen in Ampullary Cancer - A Retrospective Single Center Study. J Cancer, 2017; 8 (4): 657-664. : http://dx.doi.org/10.7150/jca.16200
  • Galiger C, Loffek S, Stemmler MP, Kroeger JK, Mittapalli VR, Fauth L, Esser PR, Kern JS, Meiss F, Lassmann S, Bruckner-Tuderman L, Franzke CW: Targeting of Cell Surface Proteolysis of Collagen XVII Impedes Squamous Cell Carcinoma Progression. Mol Ther, 2017. : http://dx.doi.org/10.1016/j.ymthe.2017.09.022 (in Druck)
  • Geddert H, Braun A, Kayser C, Dimmler A, Faller G, Agaimy A, Haller F, Moskalev EA: Epigenetic Regulation of CD133 in Gastrointestinal Stromal Tumors. Am J Clin Pathol, 2017; 147 (5): 515-524. : http://dx.doi.org/10.1093/ajcp/aqx028
  • Geissler AL, Geissler M, Kottmann D, Lutz L, Fichter CD, Fritsch R, Weddeling B, Makowiec F, Werner M, Lassmann S: ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer. Oncotarget, 2017; 8 (10): 17164-17190. : http://dx.doi.org/10.18632/oncotarget.15211
  • Gharun K, Senges J, Seidl M, Losslein A, Kolter J, Lohrmann F, Fliegauf M, Elgizouli M, Vavra M, Schachtrup K, Illert AL, Gilleron M, Kirschning CJ, Triantafyllopoulou A, Henneke P: Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells. Embo Rep, 2017; 18 (12): 2144-2159. : http://dx.doi.org/10.15252/embr.201744121
  • Hachmoeller O, Aichler M, Schamborn K, Lutz L, Werner M, Sperling M, Walch A, Karst U: Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson`s disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry. J Trace Elem Med Bio, 2017; 44: 71-75.
  • Hettmer S, Andrieux G, Hochrein J, Kurz P, Rossler J, Lassmann S, Werner M, von Bubnoff N, Peters C, Koscielniak E, Sparber-Sauer M, Niemeyer C, Mentzel T, Busch H, Boerries M: Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents. Pediatr Blood Cancer, 2017; 64 (12) (online). : http://dx.doi.org/10.1002/pbc.26675
  • Jilg CA, Drendel V, Rischke HC, Beck T, Vach W, Schaal K, Wetterauer U, Schultze-Seemann W, Meyer PT: Diagnostic Accuracy of Ga-68-HBED-CC-PSMA-Ligand-PET/CT before Salvage Lymph Node Dissection for Recurrent Prostate Cancer. Theranostics, 2017; 7 (6) (online): 1770-1780. : http://dx.doi.org/10.7150/thno.18421
  • Kaemmerer D, Sanger J, Arsenic R, D'Haese JG, Neumann J, Schmitt-Graeff A, Wirtz RM, Schulz S, Lupp A: Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas. Oncotarget, 2017; 8 (52): 89958-89969. : http://dx.doi.org/10.18632/oncotarget.21194
  • Kelly M, McNeel D, Fisch P, Malkovsky M: Immunological considerations underlying heat shock protein-mediated cancer vaccine strategies. Immunol Lett, 2017; 193: 1-10. : http://dx.doi.org/10.1016/j.imlet.2017.11.001
  • Kocsmar E, Szirtes I, Kramer Z, Szijarto A, Bene L, Buzas GM, Kenessey I, Bronsert P, Csanadi A, Lutz L, Werner M, Wellner UF, Kiss A, Schaff Z, Lotz G: Sensitivity of Helicobacter pylori detection by Giemsa staining is poor in comparison with immunohistochemistry and fluorescent in situ hybridization and strongly depends on inflammatory activity. Helicobacter, 2017; 22 (4) (online). : http://dx.doi.org/10.1111/hel.12387
  • Krebs AM, Mitschke J, Lasierra Losada M, Schmalhofer O, Boerries M, Busch H, Boettcher M, Mougiakakos D, Reichardt W, Bronsert P, Brunton VG, Pilarsky C, Winkler TH, Brabletz S, Stemmler MP, Brabletz T: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. Nat Cell Biol, 2017; 19 (5): 518-529. : http://dx.doi.org/10.1038/ncb3513
  • Kreisel W, Ruf G, Salm R, Lazaro A, Bengsch B, Globig AM, Fisch P, Lassmann S, Schmitt-Graeff A: Protein-losing pseudomembranous colitis with cap polyposis-like features. World J Gastroentero, 2017; 23 (16): 3003-3010. : http://dx.doi.org/10.3748/wjg.v23.i16.3003
  • Kronig M, Haverkamp C, Schulte A, Heinicke L, Schaal K, Drendel V, Werner M, Wetterauer U, Schultze-Seemann W, Jilg CA: Diabetes and beta-adrenergic blockage are risk factors for metastatic prostate cancer. World J Surg Oncol, 2017; 15 (1) (online): 50-50. : http://dx.doi.org/10.1186/s12957-017-1117-4
  • Kuechlin S, Schoels M, Slanchev K, Lassmann S, Walz G, Yakulov TA: EpCAM controls morphogenetic programs during zebrafish pronephros development. Biochem Bioph Res Co, 2017; 487 (2): 209-215. : http://dx.doi.org/10.1016/j.bbrc.2017.04.035
  • Kulemann B, Rosch S, Seifert S, Timme S, Bronsert P, Seifert G, Martini V, Kuvendjiska J, Glatz T, Hussung S, Fritsch R, Becker H, Pitman MB, Hoeppner J: Pancreatic cancer: Circulating Tumor Cells and Primary Tumors show Heterogeneous KRAS Mutations. Sci Rep-uk, 2017; 7 (1) (online): 4510-4510. : http://dx.doi.org/10.1038/s41598-017-04601-z
  • Kulemann B, Rosch S, Seifert S, Timme S, Bronsert P, Seifert G, Martini V, Kuvendjiska J, Glatz T, Hussung S, Fritsch R, Becker H, Pitman MB, Hoeppner J: Author Correction: Pancreatic cancer: Circulating Tumor Cells and Primary Tumors show Heterogeneous KRAS Mutations. Sci Rep-uk, 2017; 7 (1) (online): 14631-14631. : http://dx.doi.org/10.1038/s41598-017-14870-3
  • Lang S, Busch H, Boerries M, Brummer T, Timme S, Lassmann S, Aktories K, Schmidt G: Specific role of RhoC in tumor invasion and metastasis. Oncotarget, 2017; 8 (50): 87364-87378. : http://dx.doi.org/10.18632/oncotarget.20957
  • Lapshyn H, Bolm L, Kohler I, Werner M, Billmann FG, Bausch D, Hopt UT, Makowiec F, Wittel UA, Keck T, Bronsert P, Wellner UF: Histopathological tumor invasion of the mesenterico-portal vein is characterized by aggressive biology and stromal fibroblast activation. Hpb, 2017; 19 (1): 67-74. : http://dx.doi.org/10.1016/j.hpb.2016.10.002
  • Lassmann S, Haller F, Siebolts U: [Report of the molecular pathology working group]. Pathologe, 2017. : http://dx.doi.org/10.1007/s00292-017-0345-2 (in Druck)
  • Lilla N, Fullgraf H, Stetter C, Kohler S, Ernestus RI, Westermaier T: First Description of Reduced Pyruvate Dehydrogenase Enzyme Activity Following Subarachnoid Hemorrhage (SAH). Front Neurosci-switz, 2017; 11: 37-37. : http://dx.doi.org/10.3389/fnins.2017.00037
  • Limberger KA, Bogatyreva L, Todorova R, Herde B, Hauschke D, Pahl HL, Werner M, Aumann K: Tissue microarray technique is applicable to bone marrow biopsies of myeloproliferative neoplasms. Histochem Cell Biol, 2017; 147 (1): 75-82. : http://dx.doi.org/10.1007/s00418-016-1476-x
  • Maier A, Plaza-Heck P, Meixner F, Guenther F, Kaufmann BA, Kramer M, Heidt T, Zirlik A, Hilgendorf I, Reinohl J, Stachon P, Bronsert P, Birkemeyer R, Neudorfer I, Peter K, Bode C, von Zur Muhlen C: A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques. Atherosclerosis, 2017; 267: 68-77. : http://dx.doi.org/10.1016/j.atherosclerosis.2017.10.029
  • Makowiec F, Bronsert P, Klock A, Hopt UT, Neeff HP: Prognostic influence of hepatic margin after resection of colorectal liver metastasis: role of modern preoperative chemotherapy. Int J Colorectal Dis, 2017. : http://dx.doi.org/10.1007/s00384-017-2916-3
  • Metzger E, Stepputtis SS, Strietz J, Preca BT, Urban S, Willmann D, Allen A, Zenk F, Iovino N, Bronsert P, Proske A, Follo M, Boerries M, Stickeler E, Xu J, Wallace MB, Stafford JA, Kanouni T, Maurer J, Schule R: KDM4 Inhibition Targets Breast Cancer Stem-like Cells. Cancer Res, 2017; 77 (21): 5900-5912. : http://dx.doi.org/10.1158/0008-5472.CAN-17-1754
  • Minguet S, Klasener K, Schaffer AM, Fiala GJ, Osteso-Ibanez T, Raute K, Navarro-Lerida I, Hartl FA, Seidl M, Reth M, Del Pozo MA: Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance. Nat Immunol, 2017; 18 (10): 1150-1159. : http://dx.doi.org/10.1038/ni.3813
  • Petrova E, Ruckert F, Zach S, Shen Y, Weitz J, Grutzmann R, Wittel UA, Makowiec F, Hopt UT, Bronsert P, Kuhn F, Rau BM, Izrailov RE, Khatkov IE, Lapshyn H, Bolm L, Bausch D, Keck T, Wellner UF, Seifert G: Survival outcome and prognostic factors after pancreatoduodenectomy for distal bile duct carcinoma: a retrospective multicenter study. Langenbeck Arch Surg, 2017; 402 (5): 831-840. : http://dx.doi.org/10.1007/s00423-017-1590-9
  • Preca BT, Bajdak K, Mock K, Lehmann W, Sundararajan V, Bronsert P, Matzge-Ogi A, Orian-Rousseau V, Brabletz S, Brabletz T, Maurer J, Stemmler MP: A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer. Oncotarget, 2017; 8 (7): 11530-11543. : http://dx.doi.org/10.18632/oncotarget.14563
  • Rassner MP, Seidl M, Salzer U, Rajkumar SV, Epting T, Wasch R, Neumann-Haefelin E, Engelhardt M: Cast Nephropathy and Deceptively Low Absolute Serum Free Light Chain Levels: Resolution of a Challenging Case and Systematic Review of the Literature. Clin Lymphoma Myeloma Leuk, 2017. : http://dx.doi.org/10.1016/j.clml.2017.09.019 (in Druck)
  • Rathmann S, Keck C, Kreutz C, Weit N, Muller M, Timmer J, Glatzel S, Follo M, Malkovsky M, Werner M, Handgretinger R, Finke J, Fisch P: Partial break in tolerance of NKG2A(-)/LIR-1(-) single KIR(+) NK cells early in the course of HLA-matched, KIR-mismatched hematopoietic cell transplantation. Bone Marrow Transpl, 2017; 52 (8): 1144-1155. : http://dx.doi.org/10.1038/bmt.2017.81
  • Ruess DA, Kayser C, Neubauer J, Fichtner-Feigl S, Hopt UT, Wittel UA: Carcinosarcoma of the Pancreas: Case Report With Comprehensive Literature Review. Pancreas, 2017; 46 (9) (online): 1225-1233. : http://dx.doi.org/10.1097/MPA.0000000000000904
  • Schiller F, Fechter T, Zamboglou C, Chirindel A, Salman N, Jilg CA, Drendel V, Werner M, Meyer PT, Grosu AL, Mix M: Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation. Ejnmmi Res, 2017; 4 (1) (online): 21-21. : http://dx.doi.org/10.1186/s40658-017-0188-1
  • Schlenk RF, Stegelmann F, Reiter A, Jost E, Gattermann N, Hebart H, Waller C, Hochhaus A, Platzbecker U, Schafhausen P, Blau IW, Verbeek W, Heidel FH, Werner M, Kreipe H, Teleanu V, Benner A, Dohner H, Griesshammer M, Dohner K: Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis. Leukemia, 2017; 31 (4): 889-895. : http://dx.doi.org/10.1038/leu.2016.299
  • Shahinian JH, Mayer B, Tholen S, Brehm K, Biniossek ML, Fullgraf H, Kiefer S, Heizmann U, Heilmann C, Ruter F, Grapow M, Reuthebuch OT, Eckstein F, Beyersdorf F, Schilling O, Siepe M: Proteomics highlights decrease of matricellular proteins in left ventricular assist device therapydagger. Eur J Cardio-thorac, 2017; 51 (6): 1063-1071. : http://dx.doi.org/10.1093/ejcts/ezx023
  • Sillem M, Timme S, Bronsert P, Bogatyreva L, Hauschke D, Zur Hausen A, Werner M, Stickeler E: Anti-Phosphohistone H3-Positive Mitoses Are Linked to Pathological Response in Neoadjuvantly Treated Breast Cancer. Breast Care, 2017; 12 (4): 244-250. : http://dx.doi.org/10.1159/000463377
  • Smulski CR, Kury P, Seidel LM, Staiger HS, Edinger AK, Willen L, Seidl M, Hess H, Salzer U, Rolink AG, Rizzi M, Schneider P, Eibel H: BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells. Cell Rep, 2017; 18 (9): 2189-2202. : http://dx.doi.org/10.1016/j.celrep.2017.02.005
  • Speckmann C, Sahoo SS, Rizzi M, Hirabayashi S, Karow A, Serwas NK, Hoemberg M, Damatova N, Schindler D, Vannier JB, Boulton SJ, Pannicke U, Gohring G, Thomay K, Verdu-Amoros JJ, Hauch H, Woessmann W, Escherich G, Laack E, Rindle L, Seidl M, Rensing-Ehl A, Lausch E, Jandrasits C, Strahm B, Schwarz K, Ehl SR, Niemeyer C, Boztug K, Wlodarski MW: Corrigendum: Clinical and Molecular Heterogeneity of RTEL1 Deficiency. Front Immunol, 2017; 8 (online): 1250-1250. : http://dx.doi.org/10.3389/fimmu.2017.01250
  • Speckmann C, Sahoo SS, Rizzi M, Hirabayashi S, Karow A, Serwas NK, Hoemberg M, Damatova N, Schindler D, Vannier JB, Boulton SJ, Pannicke U, Gohring G, Thomay K, Verdu-Amoros JJ, Hauch H, Woessmann W, Escherich G, Laack E, Rindle L, Seidl M, Rensing-Ehl A, Lausch E, Jandrasits C, Strahm B, Schwarz K, Ehl SR, Niemeyer C, Boztug K, Wlodarski MW: Clinical and Molecular Heterogeneity of RTEL1 Deficiency. Front Immunol, 2017; 8 (online): 449-449. : http://dx.doi.org/10.3389/fimmu.2017.00449
  • Stickel N, Hanke K, Marschner D, Prinz G, Kohler M, Melchinger W, Pfeifer D, Schmitt-Graeff A, Brummer T, Heine A, Brossart P, Wolf D, von Bubnoff N, Finke J, Duyster J, Ferrara J, Salzer U, Zeiser R: MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation. Leukemia, 2017; 31 (12): 2732-2741. : http://dx.doi.org/10.1038/leu.2017.137
  • Stoykow C, Huber-Schumacher S, Almanasreh N, Jilg C, Ruf J: Strong PMSA Radioligand Uptake by Rectal Carcinoma: Who Put the "S" in PSMA? Clin Nucl Med, 2017; 42 (3) (online): 225-226. : http://dx.doi.org/10.1097/RLU.0000000000001484
  • Tegtmeyer D, Seidl M, Gerner P, Baumann U, Klemann C: Inflammatory bowel disease caused by primary immunodeficiencies-Clinical presentations, review of literature, and proposal of a rational diagnostic algorithm. Pediat Allerg Imm-uk, 2017; 28 (5): 412-429. : http://dx.doi.org/10.1111/pai.12734
  • Thomsen AR, Aldrian C, Bronsert P, Thomann Y, Nanko N, Melin N, Rucker G, Follo M, Grosu AL, Niedermann G, Layer PG, Heselich A, Lund PG: A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement. Lab Chip, 2017. : http://dx.doi.org/10.1039/c7lc00832e
  • Unger S, Seidl M, van Schouwenburg P, Rakhmanov M, Bulashevska A, Frede N, Grimbacher B, Pfeiffer J, Schrenk K, Munoz L, Hanitsch L, Stumpf I, Kaiser F, Hausmann O, Kollert F, Goldacker S, van der Burg M, Keller B, Warnatz K: The TH1 phenotype of follicular helper T cells indicates an IFN-gamma-associated immune dysregulation in patients with CD21low common variable immunodeficiency. J Allergy Clin Immun, 2017. : http://dx.doi.org/10.1016/j.jaci.2017.04.041 (in Druck)
  • van de Ven AAJM, Seidl M, Drendel V, Schmitt-Graeff A, Voll RE, Rensing-Ehl A, Speckmann C, Ehl S, Warnatz K, Kollert F: IgG4-related disease in autoimmune lymphoproliferative syndrome. Clin Immunol, 2017; 180: 97-99. : http://dx.doi.org/10.1016/j.clim.2017.05.003
  • Weinberg F, Reischmann N, Fauth L, Taromi S, Mastroianni J, Kohler M, Halbach S, Becker AC, Deng N, Schmitz T, Uhl FM, Herbener N, Riedel B, Beier F, Swarbrick A, Lassmann S, Dengjel J, Zeiser R, Brummer T: The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior. EBioMedicine, 2017; 20: 79-97. : http://dx.doi.org/10.1016/j.ebiom.2017.04.015
  • Werner K, Kullenberg de Gaudry D, Taylor LA, Keck T, Unger C, Hopt UT, Massing U: Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial. Lipids Health Dis, 2017; 16 (1) (online): 104-104. : http://dx.doi.org/10.1186/s12944-017-0495-5
  • Wieser G, Popp I, Christian Rischke H, Drendel V, Grosu AL, Bartholoma M, Weber WA, Mansi R, Wetterauer U, Schultze-Seemann W, Meyer PT, Jilg CA: Diagnosis of recurrent prostate cancer with PET/CT imaging using the gastrin-releasing peptide receptor antagonist (68)Ga-RM2: Preliminary results in patients with negative or inconclusive [(18)F]Fluoroethylcholine-PET/CT. Eur J Nucl Med Mol I, 2017; 44 (9): 1463-1472. : http://dx.doi.org/10.1007/s00259-017-3702-8
  • Zahaf NI, Lang AE, Kaiser L, Fichter CD, Lassmann S, McCluskey A, Augspach A, Aktories K, Schmidt G: Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells. Sci Rep-uk, 2017; 7 (online): 41252-41252. : http://dx.doi.org/10.1038/srep41252
  • Zamboglou C, Drendel V, Jilg CA, Rischke HC, Beck TI, Schultze-Seemann W, Krauss T, Mix M, Schiller F, Wetterauer U, Werner M, Langer M, Bock M, Meyer PT, Grosu AL: Comparison of 68Ga-HBED-CC PSMA-PET/CT and multiparametric MRI for gross tumour volume detection in patients with primary prostate cancer based on slice by slice comparison with histopathology. Theranostics, 2017; 7 (1) (online): 228-237. : http://dx.doi.org/10.7150/thno.16638

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten

Promotionen
  • Heckelmann Bianca Herta: Vergleichende Analysen des Proteoms ausgewählter renaler Neoplasien, 2017.
  • Jenneßen Diana Ilona: Korrelatin der Morphologie von Liposarkomen mit klinisch-pathologischen Parametern (Erstgutachter/in PD Dr med. Gyan Kayser, Pathologie, Zweitgutachter/in Prof. Dr. med. Holger Bannasch, Klinik für Plastische und Handchirurgie), 2017.
  • Niermann Kathrin: Qualitative Analyse von pathologischen Befundberichten onkologischer Mammaresektate (Erstgutachter/in Prof. Dr. Martin Werner, Pathologie, Zweitgutachter/in Prof. Dr. Gerald Gitsch, Klinik für Frauenheilkunde), 2017.
  • Thiele Katharina Nadja: Funktionelle Analysen des tumorrelevanten Faktors Osteopontin in gynäkologischen Tumoren (Erstgutachter/in Prof. Dr. Stickeler, Klinik für Frauenheilkunde, Zweitgutachter/in Prof. Dr. Martin Werner, Pathologie), 2017.
  • Todorova Rumyana: Expressionsanalysen Myelofibrose-assoziierter Gene/Proteine und digitale morphometrische Analysen in Knochenmarkbiopsien von MPN-Patienten (Erstgutachter/in Prof. Dr. Martin Werner, Pathologie, Zweitgutachter/in Prof. Dr. Heike L. Pahl, Innere Medizin), 2017.