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 Forschungsbericht für das Jahr 2017

Universitäts-Herzzentrum Freiburg - Bad Krozingen

Klinik für Kardiologie und Angiologie I

Hugstetter Str. 55
79106 Freiburg
Tel: 0761/270-34432 Fax: 0761/270-34435
Email maria.roth@universitaets-herzzentrum.de
http://www.herzzentrum.de/kliniken-fachbereiche/klinik-fuer-kardiologie-und-angiologie-i.html


Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Binder Sk, Wengenmayer T, Bode C, Dürschmied D, Staudacher D: Isoflurane or propofol sedation in patients with targeted temperature management after cardiopulmonary resuscitation: A retrospective single center study Resuscitation, 2017; 118: e83.
  • Brado J, Dechant MJ, Menza M, Komancsek A, Lang CN, Bugger H, Foell D, Jung BA, Stiller B, Bode C, Odening KE: Phase-contrast magnet resonance imaging reveals regional, transmural, and Heart Rhythm, 2017; 14 (9): 1388-1397. : http://dx.doi.org/10.1016/j.hrthm.2017.04.045
  • Breitbart P, Minners J, Pache G, Reinohl J, Hansson NC, Norgaard BL, Neumann FJ, Ruile P: Outcomes in patients with contained ruptures of the aortic annulus after transcatheter aortic valve implantation with balloon-expandable devices. Eurointervention, 2017. : http://dx.doi.org/10.4244/EIJ-D-17-00347 (in Druck)
  • Claes S, Berchtold-Herz M, Zhou Q, Trummer G, Bock M, Zirlik A, Beyersdorf F, Bode C, Grundmann S: Towards a cardiac allocation score: a retrospective calculation for 73 patients from a German transplant center. J Cardiothorac Surg, 2017; 12 (1): 14-14. : http://dx.doi.org/10.1186/s13019-017-0575-7
  • Claeys MJ, Ahrens I, Sinnaeve P, Diletti R, Rossini R, Goldstein P, Czerwinska K, Bueno H, Lettino M, Munzel T, Zeymer U: Editor's Choice-The organization of chest pain units: Position statement of the Acute Cardiovascular Care Association. Eur Heart J Acute Cardiovasc Care, 2017; 6 (3): 203-211. : http://dx.doi.org/10.1177/2048872617695236
  • Darr R, Kuhn M, Bode C, Bornstein SR, Pacak K, Lenders JWM, Eisenhofer G: Accuracy of recommended sampling and assay methods for the determination of plasma-free and urinary fractionated metanephrines in the diagnosis of pheochromocytoma and paraganglioma: a systematic review. Endocrine, 2017; 56 (3): 495-503. : http://dx.doi.org/10.1007/s12020-017-1300-y
  • Deharo P, Ducrocq G, Bode C, Cohen M, Cuisset T, Mehta SR, Pollack C Jr, Wiviott SD, Elbez Y, Sabatine MS, Steg PG: Timing of Angiography and Outcomes in High-Risk Patients With Non-ST-Segment-Elevation Myocardial Infarction Managed Invasively: Insights From the TAO Trial (Treatment of Acute Coronary Syndrome With Otamixaban). Circulation, 2017; 136 (20): 1895-1907. : http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029779
  • Dressler FF, Bodi I, Menza M, Moss R, Bugger H, Bode C, Behrends JC, Seemann G, Odening KE: Interregional electro-mechanical heterogeneity in the rabbit myocardium. Prog Biophys Mol Bio, 2017; 130: 344-355. : http://dx.doi.org/10.1016/j.pbiomolbio.2017.06.016
  • Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M: The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovasc Res, 2017; 113 (2): 222-223. : http://dx.doi.org/10.1093/cvr/cvw248
  • Esser JS, Saretzki E, Pankratz F, Engert B, Grundmann S, Bode C, Moser M*, Zhou Q*: Bone morphogenetic protein 4 regulates microRNAs miR-494 and miR-126-5p in control of endothelial cell function in angiogenesis. Thromb Haemostasis, 2017; 117 (4): 734-749. : http://dx.doi.org/10.1160/TH16-08-0643
  • Fanola CL, Morrow DA, Cannon CP, Jarolim P, Lukas MA, Bode C, Hochman JS, Goodrich EL, Braunwald E, O'Donoghue ML: Interleukin-6 and the Risk of Adverse Outcomes in Patients After an Acute Coronary Syndrome: Observations From the SOLID-TIMI 52 (Stabilization of Plaque Using Darapladib-Thrombolysis in Myocardial Infarction 52) Trial. J Am Heart Assoc, 2017; 6 (10): e005637-e005637. : http://dx.doi.org/10.1161/JAHA.117.005637
  • Gibson CM, Pinto DS, Chi G, Arbetter D, Yee M, Mehran R, Bode C, Halperin J, Verheugt FW, Wildgoose P, Burton P, van Eickels M, Korjian S, Daaboul Y, Jain P, Lip GY, Cohen M, Peterson ED, Fox KA: Recurrent Hospitalization Among Patients With Atrial Fibrillation Undergoing Intracoronary Stenting Treated With 2 Treatment Strategies of Rivaroxaban or a Dose-Adjusted Oral Vitamin K Antagonist Treatment Strategy. Circulation, 2017; 135 (4): 323-333. : http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025783
  • Gieldon L, Masjkur JR, Richter S, Darr R, Lahera M, Aust DE, Zeugner S, Rump A, Hackmann K, Tzschach A, Januszewicz A, Prejbisz A, Eisenhofer G, Schroeck E, Robledo M, Klink B: Next generation panel sequencing identifies NF1 germline mutations in three patients with pheochromocytoma but no clinical diagnosis of Neurofibromatosis Type 1. Eur J Endocrinol, 2017. : http://dx.doi.org/10.1530/EJE-17-0714 (in Druck)
  • Gimpel C, Jung BA, Jung S, Brado J, Schwendinger D, Burkhardt B, Pohl M, Odening KE, Geiger J, Arnold R: Magnetic resonance tissue phase mapping demonstrates altered left ventricular diastolic function in children with chronic kidney disease. Pediatr Radiol, 2017; 47 (2): 169-177. : http://dx.doi.org/10.1007/s00247-016-3741-5
  • Greil C, Roether F, La Rosee P, Grimbacher B, Duerschmied D*, Warnatz K*: Rescue of Cytokine Storm Due to HLH by Hemoadsorption in a CTLA4-Deficient Patient. J Clin Immunol, 2017; 37 (3): 273-276. : http://dx.doi.org/10.1007/s10875-017-0377-7
  • Grunert SC, Bodi I, Odening KE: Possible mechanisms for sensorineural hearing loss and deafness in patients with propionic acidemia. Orphanet J Rare Dis, 2017; 12 (1): 30-30. : http://dx.doi.org/10.1186/s13023-017-0585-5
  • Gunther F, Heidt T, Kramer M, Khanicheh E, Klibanov AL, Geibel-Zehender A, Ferrante EA, Hilgendorf I, Wolf D, Zirlik A, Reinohl J, Bode C, Peter K, Kaufmann BA, Muhlen CVZ: Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis. Sci Rep-uk, 2017; 7 (1): 14898-14898. : http://dx.doi.org/10.1038/s41598-017-15080-7
  • Gutmann A, Kaier K, Reinecke H, Frankenstein L, Zirlik A, Bothe W, von Zur Muhlen C, Zehender M, Reinohl J, Bode C, Stachon P: Impact of pulmonary hypertension on in-hospital outcome after surgical or transcatheter aortic valve replacement. Eurointervention, 2017; 13 (7): 804-810. : http://dx.doi.org/10.4244/EIJ-D-16-00927
  • Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong SL, Gallant M, Cifuni S, Leng Y, Wagner DD: Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice. Plos One, 2017. (in Druck)
  • Helbing T, Arnold L, Wiltgen G, Hirschbihl E, Gabelmann V, Hornstein A, Esser JS, Diehl P, Grundmann S, Busch HJ, Fink K, Bode C, Moser M: Endothelial BMP4 Regulates Leukocyte Diapedesis and Promotes Inflammation. Inflammation, 2017; 40 (6): 1862-1874. : http://dx.doi.org/10.1007/s10753-017-0627-0
  • Helbing T, Wiltgen G, Hornstein A, Brauers EZ, Arnold L, Bauer A, Esser JS, Diehl P, Grundmann S, Fink K, Patterson C, Bode C, Moser M: Bone Morphogenetic Protein-Modulator BMPER Regulates Endothelial Barrier Function. Inflammation, 2017; 40 (2): 442-453. : http://dx.doi.org/10.1007/s10753-016-0490-4
  • Hortmann M, Duerschmied D, Bode C, Ahrens I: Chip-based Digital PCR as a Novel Detection Method for Quantifying microRNAs in Acute Myocardial Infarction. Acta Pharmacol Sin, 2017; Oct. (in Druck)
  • Hortmann M, Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Dürschmied D, Peter K, Bode C, Ahrens I: Droplet Digital PCR as a Novel Detection Method for Quantifying micro-RNAs in Acute Myocardial Infarction Clin Res Cardiol, 2017; 106 Suppl. 1: 1.
  • Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Laumann R, Stallmann D, Reinoehl J, Duerschmied D, Peter K, Bode C, Ahrens I: Circulating HtrA2 after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A potential novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury. Int J Cardiol, 2017; 249: 437-437. : http://dx.doi.org/10.1016/j.ijcard.2017.08.022
  • Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Stallmann D, Reinoehl J, Duerschmied D, Peter K, Bode C, Ahrens I: Circulating HtrA2 as a novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury in ST-segment elevation myocardial infarction. Int J Cardiol, 2017; 243: 485-491. : http://dx.doi.org/10.1016/j.ijcard.2017.05.088
  • Hortmann M, Robinson S, Mohr M, Mauler M, Stallmann D, Reinohl J, Duerschmied D, Peter K, Carr J, Gibson CM, Bode C, Ahrens I: The mitochondria-targeting peptide elamipretide diminishes circulating HtrA2 in ST-segment elevation myocardial infarction. Eur Heart J Acute Cardiovasc Care, 2017. : http://dx.doi.org/10.1177/2048872617710789 (in Druck)
  • Htun NM, Magliano DJ, Zhang ZY, Lyons J, Petit T, Nkuipou-Kenfack E, Ramirez-Torres A, von Zur Muhlen C, Maahs D, Schanstra JP, Pontillo C, Pejchinovski M, Snell-Bergeon JK, Delles C, Mischak H, Staessen JA, Shaw JE, Koeck T, Peter K: Prediction of acute coronary syndromes by urinary proteome analysis. Plos One, 2017; 12 (3): e0172036-e0172036. : http://dx.doi.org/10.1371/journal.pone.0172036
  • Kaier K, Reinecke H, Naci H, Frankenstein L, Bode M, Vach W, Hehn P, Zirlik A, Zehender M, Reinohl J: The impact of post-procedural complications on reimbursement, length of stay and mechanical ventilation among patients undergoing transcatheter aortic valve implantation in Germany. Eur J Health Econ, 2017. : http://dx.doi.org/10.1007/s10198-017-0877-7 (in Druck)
  • Kaier K, Reinecke H, Schmoor C, Frankenstein L, Vach W, Hehn P, Zirlik A, Bode C, Zehender M, Reinohl J: Learning Curves Among All Patients Undergoing Transcatheter Aortic Valve Implantation in Germany: A Retrospective Observational Study. Int J Cardiol, 2017; 235: 17-21. : http://dx.doi.org/10.1016/j.ijcard.2017.02.138
  • Kaier K, von Kampen F, Baumbach H, von Zur Muhlen C, Hehn P, Vach W, Zehender M, Bode C, Reinohl J: Two-year post-discharge costs of care among patients treated with transcatheter or surgical aortic valve replacement in Germany. Bmc Health Serv Res, 2017; 17 (1): 473-473. : http://dx.doi.org/10.1186/s12913-017-2432-8
  • Klenze H, Kohler TC, Farquharson F, Walterspacher S, Duerschmied D, Roecker K, Kabitz HJ, Walker DJ: Resting limb muscle perfusion during inspiratory muscle loading in hypoxia and normoxia. Resp Physiol Neurobi, 2017; 244: 1-9. : http://dx.doi.org/10.1016/j.resp.2017.06.003
  • Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galie N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jimenez D, Kozak M, Lang IM, Lankeit M, Munzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV: Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thromb Haemostasis, 2017; 117 (12): 2425-2434. : http://dx.doi.org/10.1160/TH17-06-0434
  • Koentges H, Pepin ME, Müsse C, Pfeil K, Viteri Alvarez SV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR, Bugger H: Gene Expression Analysis to Identify Mechanisms Underlying Heart Failure Susceptibility in Mice and Humans. Basic Res Cardiol, 2017. (in Druck)
  • Konstantinides SV, Vicaut E, Danays T, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Dellas C, Duerschmied D, Empen K, Ferrari E, Galie N, Jimenez D, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N, Palazzini M, Pruszczyk P, Rugolotto M, Salvi A, Sanchez O, Schellong S, Sobkowicz B, Meyer G: Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. J Am Coll Cardiol, 2017; 69 (12): 1536-1544. : http://dx.doi.org/10.1016/j.jacc.2016.12.039
  • Krieger K*, Steinfurt J*, Lenz C, Keweloh B: Catheter Ablation of Brugada Syndrome: Importance of Repeated Administration of Ajmaline to Unmask the Entire Epicardial Substrate JACC Clinical Electrophysiology, 2017; 3 (11): 1330-1332. : https://doi.org/10.1016/j.jacep.2017.02.014
  • Kroll KT, Zhou Q, Kohl P: Finding the culprit: who is turning hearts to stone? Stem Cell Investig, 2017; 4: 33-33. : http://dx.doi.org/10.21037/sci.2017.03.02
  • Krueger K, Schmutz A, Zieger B, Kalbhenn J: Venovenous Extracorporeal Membrane Oxygenation With Prophylactic Subcutaneous Anticoagulation Only: An Observational Study in More Than 60 Patients. Artif Organs, 2017; 41 (2): 186-192. : http://dx.doi.org/10.1111/aor.12737
  • Lother A, Bergemann S, Kowalski J, Huck M, Gilsbach R, Bode C, Hein L: Inhibition of the cardiac myocyte mineralocorticoid receptor ameliorates doxorubicin-induced cardiotoxicity. Cardiovasc Res, 2017. : http://dx.doi.org/10.1093/cvr/cvx078 (in Druck)
  • Luders F, Kaier K, Kaleschke G, Gebauer K, Meyborg M, Malyar NM, Freisinger E, Baumgartner H, Reinecke H, Reinohl J: Association of CKD with Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation. Clin J Am Soc Nephro, 2017; 12 (5): 718-726. : http://dx.doi.org/10.2215/CJN.10471016
  • Ludwig B*, Zotzmann V*, Bode C, Staudacher DL*, Zschiedrich S*: Lethal pulmonary hemorrhage syndrome due to Leptospira infection transmitted by pet rat. IDCases, 2017; 8: 84-86. : http://dx.doi.org/10.1016/j.idcr.2017.04.016
  • Maier A, Plaza-Heck P, Meixner F, Guenther F, Kaufmann BA, Kramer M, Heidt T, Zirlik A, Hilgendorf I, Reinohl J, Stachon P, Bronsert P, Birkemeyer R, Neudorfer I, Peter K, Bode C, von Zur Muhlen C: A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques. Atherosclerosis, 2017; 267: 68-77. : http://dx.doi.org/10.1016/j.atherosclerosis.2017.10.029
  • Malyar NM, Kaier K, Freisinger E, Luders F, Kaleschke G, Baumgartner H, Frankenstein L, Reinecke H, Reinohl J: Prevalence and Impact of Critical Limb Ischemia on In-Hospital Outcome in Transcatheter Aortic Valve Implantation in Germany. Eurointervention, 2017. : http://dx.doi.org/10.4244/EIJ-D-17-00228 (in Druck)
  • Martinod K*, Witsch T*, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD: Peptidylarginine deiminase 4 promotes age-related organ fibrosis. J Exp Med, 2017; 214 (2): 439-458. : http://dx.doi.org/10.1084/jem.20160530
  • Menza M, Foll D, Hennig J, Jung B: Segmental biventricular analysis of myocardial function using high temporal and spatial resolution tissue phase mapping. Magn Reson Mater Phy, 2017. : http://dx.doi.org/10.1007/s10334-017-0661-9 (in Druck)
  • Ohman EM, Roe MT, Steg PG, James SK, Povsic TJ, White J, Rockhold F, Plotnikov A, Mundl H, Strony J, Sun X, Husted S, Tendera M, Montalescot G, Bahit MC, Ardissino D, Bueno H, Claeys MJ, Nicolau JC, Cornel JH, Goto S, Kiss RG, Guray U, Park DW, Bode C, Welsh RC, Gibson CM: Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial. Lancet, 2017; 389 (10081): 1799-1808. : http://dx.doi.org/10.1016/S0140-6736(17)30751-1
  • Patzelt J, Zhang Y, Magunia H, Jorbenadze R, Droppa M, Ulrich M, Cai S, Lausberg H, Walker T, Wengenmayer T, Rosenberger P, Schreieck J, Seizer P, Gawaz M, Langer HF: Immediate increase of cardiac output after percutaneous mitral valve repair (PMVR) determined by echocardiographic and invasive parameters: Patzelt: Increase of cardiac output after PMVR. Int J Cardiol, 2017; 236: 356-362. : http://dx.doi.org/10.1016/j.ijcard.2016.12.190
  • Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Heger LA, Helbing T, Duerschmied D, Peter K, Bode C, Ahrens I, Hortmann M: Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients. Acta Pharmacol Sin, 2017. : http://dx.doi.org/10.1038/aps.2017.136 (in Druck)
  • Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Tewari M, Duerschmied D, Peter K, Bode C, Ahrens I*, Hortmann M*: Droplet Digital PCR as a Novel Detection Method for Quantifying microRNAs in Acute Myocardial Infarction Int J Cardiol, 2017. (in Druck)
  • Ruile P, Jander N, Blanke P, Schoechlin S, Reinohl J, Gick M, Rothe J, Langer M, Leipsic J, Buettner HJ, Neumann FJ, Pache G: Course of early subclinical leaflet thrombosis after transcatheter aortic valve implantation with or without oral anticoagulation. Clin Res Cardiol, 2017; 106 (2): 85-95. : http://dx.doi.org/10.1007/s00392-016-1052-3
  • Schmitz E, Bischoff B, Wolf D, Schmitt HJ, Eyupoglu IY, Roessler K, Buchfelder M, Sommer B: Intraoperative Vascular Neuromonitoring in Patients with Subarachnoid Hemorrhage: A Pilot Study Using Combined Laser-Doppler Spectrophotometry. World Neurosurg, 2017; 107: 542-548. : http://dx.doi.org/10.1016/j.wneu.2017.08.011
  • Sommer B, Kreuzer M, Bischoff B, Wolf D, Schmitt H, Eyupoglu IY, Rossler K, Buchfelder M, Ganslandt O, Wiendieck K: Combined Laser-Doppler Flowmetry and Spectrophotometry: Feasibility Study of a Novel Device for Monitoring Local Cortical Microcirculation during Aneurysm Surgery. J Neurol Surg Part A, 2017; 78 (1): 1-11. : http://dx.doi.org/10.1055/s-0036-1584510
  • Sommer B, Weidinger CS, Wolf D, Buchfelder M, Schmitt H: Intraoperative continuous cerebral microcirculation measurement in patients with aneurysmal subarachnoid hemorrhage: preliminary data on the early administration of magnesium sulfate. Bmc Anesthesiol, 2017; 17 (1): 143-143. : http://dx.doi.org/10.1186/s12871-017-0435-y
  • Stachon P, Heidenreich A, Merz J, Hilgendorf I, Wolf D, Willecke F, von Garlen S, Albrecht P, Hardtner C, Ehrat N, Hoppe N, Reinohl J, von Zur Muhlen C, Bode C, Idzko M, Zirlik A: P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice. Circulation, 2017; 135 (25): 2524-2533. : http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027400
  • Stachon P, Kalbhenn J, Walterspacher S, Bode C, Staudacher D: [Near-Drowning with Good Outcome after ECMO-Therapy and Therapeutic Hypothermia Despite 20 Minutes of Anoxia and 16 Hours of Hypoxia]. Deut Med Wochenschr, 2017; 142 (8): 596-600. : http://dx.doi.org/10.1055/s-0043-101530
  • Staudacher D, Biever P, Benk C, Bode C, Wengenmayer T: Extracorporeal cardiopulmonary resuscitation during out of office hours: A single center registry study Resuscitation, 2017; 118: 40e-40e. : https://doi.org/10.1016/j.resuscitation.2017.08.103
  • Staudacher DL, Bode C, Wengenmayer T: Time matters in patients undergoing extracorporeal cardiopulmonary resuscitation. Resuscitation, 2017; 116: e11-e11. : http://dx.doi.org/10.1016/j.resuscitation.2017.04.026
  • Staudacher DL, Gold W, Biever PM, Bode C, Wengenmayer T: Early fluid resuscitation and volume therapy in venoarterial extracorporeal membrane oxygenation. J Crit Care, 2017; 37: 130-135. : http://dx.doi.org/10.1016/j.jcrc.2016.09.017
  • Staudacher DL, Putz V, Heger L, Reinohl J, Hortmann M, Zelenkofske SL, Becker RC, Rusconi CP, Bode C, Ahrens I: Direct factor IXa inhibition with the RNA-aptamer pegnivacogin reduces platelet reactivity in vitro and residual platelet aggregation in patients with acute coronary syndromes. Eur Heart J Acute Cardiovasc Care, 2017. : http://dx.doi.org/10.1177/2048872617703065 (in Druck)
  • Supady A, Wengenmayer T, Bode C, Staudacher D: Left ventricular unloading during extracorporeal life support (ECLS) by percutaneous ventricular assist device (PVAD) therapy in patients with severe cardiogenic shock Resuscitation, 2017; 118: e77-e78.
  • Trummer G, Supady A, Beyersdorf F, Scherer C, Wengenmayer T, Umhau M, Benk C: Controlled automated reperfusion of the whole body after 120 minutes of Cardiopulmonary resuscitation: first clinical report. Scand J Trauma Resus, 2017; 25 (1): 66-66. : http://dx.doi.org/10.1186/s13049-017-0412-y
  • Tsushima K*, Bugger H*, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Black CL, Pereira RO, Lira VA, Spitzer K, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED: Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Circ Res, 2017. : http://dx.doi.org/10.1161/CIRCRESAHA.117.311307 (in Druck)
  • Wengenmayer T, Dürschmied D, Graf E, Chiabudini M, Benk C, Mühlschlegel S, Philipp A, Lubnow M, Bode C, Staudacher D: Development and external validation of a prognostic model for hospital survival in patients on venoarterial extracorporeal membrane oxygenation therapy using point of care biomarkers: The PREDICT-VA-ECMO score Resuscitation, 2017; 118: e29.
  • Wengenmayer T, Reinohl J, Steinfurt J, Mittag A, Bode C, Biermann J: Implantation of CARILLON(R) Mitral Contour System with transvenous left ventricular lead in place. Clin Res Cardiol, 2017; 106 (10): 796-801. : http://dx.doi.org/10.1007/s00392-017-1121-2
  • Wengenmayer T, Rombach S, Ramshorn F, Biever P, Bode C, Duerschmied D, Staudacher DL: Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR). Crit Care, 2017; 21 (1): 157-157. : http://dx.doi.org/10.1186/s13054-017-1744-8
  • Wengenmayer T, Stephan A, Grundmann S, Foll D, Beyersdorf F, Bode C, Geibel A: Altered Regional Myocardial Mechanics in Transplanted Hearts: Influence of Time and Transplantation. Thorac Cardiov Surg, 2017; 65 (5): 415-422. : http://dx.doi.org/10.1055/s-0036-1597591
  • Witsch T, Martinod K, Sorvillo N, Portier I, De Meyer S, Wagner DD: rhADAMTS13 treatment improves myocardial remodeling and functionality after pressure overload injury in mice. JAHA, 2017. (in Druck)
  • Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinohl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A: Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO). Thromb Haemostasis, 2017; 117 (2): 325-338. : http://dx.doi.org/10.1160/TH16-07-0553
  • Zeng Y, Cavalcante R, Tenekecioglu E, Suwannasom P, Sotomi Y, Collet C, Abdelghani M, Jonker H, Digne F, Horstkotte D, Zehender M, Indolfi C, Saia F, Fiorilli R, Chevalier B, Bolognese L, Goicolea J, Nie S, Onuma Y, Serruys PW: Comparative assessment of "plaque/media" change on three modalities of IVUS immediately after implantation of either everolimus-eluting bioresorbable vascular scaffold or everolimus-eluting metallic stent in Absorb II study. Int J Cardiovas Imag, 2017; 33 (4): 441-449. : http://dx.doi.org/10.1007/s10554-016-1033-7
  • Zotzmann V, Wengenmayer T, Biever P, Bode C, Staudacher D: Diagnostic and therapeutic value of coronary angiography and CT-scan after extracorporeal cardiopulmonary resuscitation (eCPR)–A single center registry study Resuscitation, 2017; 118: e28-e29.
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
  • Duerschmied D, Bode C: Register und Studien zu den NOAKs sowie klinischer Stellenwert der Antidots Der Klinikarzt, 2017; 46 (03): 92-98.
  • Helms TM, Gulba D, Ahrens I, Schafer A, Hankowitz J, Kuhlencordt P, Lipp HP, Nikol S, Riess H, Stargardt T, Bramlage P: [Treatment and Secondary Prevention of Venous Thromboembolism - Change in Oral Anticoagulation]. Deut Med Wochenschr, 2017; 142 (13): 986-993. : http://dx.doi.org/10.1055/s-0042-124132
  • Herr N, Bode C, Duerschmied D: The Effects of Serotonin in Immune Cells. Front Cardiovasc Med, 2017; 4: 48-48. : http://dx.doi.org/10.3389/fcvm.2017.00048
  • Lang CN, Steinfurt J, Odening KE: Avoiding sports-related sudden cardiac death in children with congenital channelopathy : Recommendations for sports activities. Herz, 2017; 42 (2): 162-170. : http://dx.doi.org/10.1007/s00059-017-4549-2
  • Michel NA, Zirlik A, Wolf D: CD40L and Its Receptors in Atherothrombosis-An Update. Front Cardiovasc Med, 2017; 4: 40-40. : http://dx.doi.org/10.3389/fcvm.2017.00040
  • Odening KE, Ziupa D: Transgenic animal models of cardiac channelopathies – benefits and limitations. Springer Book "Channelopathies in Heart Disease", 2017. (in Druck)
  • Olivier CB, Bode C, Moser M: Antithrombotische Therapie bei Vorhofflimmern und perkutaner Koronarintervention/akutem Koronarsyndrom. Aktuelle Kardiologie, 2017; 6: 367-372.
  • Ravens U, Odening KE: Atrial fibrillation: Therapeutic potential of atrial K+ channel blockers. Pharmacol Therapeut, 2017; 176: 13-21. : http://dx.doi.org/10.1016/j.pharmthera.2016.10.003
  • Schmutz A, Benk C, Wengenmayer T: Venovenöse extrakorporale Membranoxygenierung Kardiologie up2date, 2017; 13 (03): 255- 272. : http://DOI: 10.1055/s-0043-117247
  • Staudacher DL, Biever PM, Dürschmied D, Wengenmayer T, Bode C, Ahrens I: Passagere Herzunterstützungssysteme Notfall Rettungsmed, 2017; 20 (1): 63-74. : http://DOI 10.1007/s10049-016-0264-4
  • Winter MP, Grove EL, De Caterina R, Gorog DA, Ahrens I, Geisler T, Gurbel PA, Tantry U, Navarese EP, Siller-Matula JM: Advocating cardiovascular precision medicine with P2Y12 receptor inhibitors. Eur Heart J Cardiovasc Pharmacother, 2017; 3 (4): 221-234. : http://dx.doi.org/10.1093/ehjcvp/pvw044
  • Zhou Q, Bode C, Zirlik A: Resistente Hypertonie – ein Compliance Problem? Der Hausarzt, 2017; 08: 44-48.
  • Zirlik A, Bode C: Vitamin K antagonists: relative strengths and weaknesses vs. direct oral anticoagulants for stroke prevention in patients with atrial fibrillation. J Thromb Thrombolys, 2017; 43 (3): 365-379. : http://dx.doi.org/10.1007/s11239-016-1446-0
Buchbeiträge:
  • Ahrens I, Bueno H: Platelet Inhibition as a Therapeutic Approach in Intravascular Intervention In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 99-109.: http://10.1007/978-3-319-66224-4
  • Duerschmied D, Massberg S: Platelets as Regulators of Thrombosis and Inflammation In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 53-80.: http://10.1007/978-3-319-66224-4
  • Hilgendorf I, Swirski FK: Diversity of Inflammatory Cells in Vascular Degenerative Disease In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 81-98.: http://10.1007/978-3-319-66224-4
  • Mammadova-Bach E, Mauler M, Braun A, Duerschmied D: Immuno-thrombotic effects of platelet serotonin In: Serotonin Rijeka, Croatia: InTech, 2017.
  • Moser M, Diehl P: Microparticles: Surrogate Markers and Promoters of Cardiovascular Diseases In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 125-135.: http://10.1007/978-3-319-66224-4
  • Stachon P, Zirlik A: In the Heat of the Artery: Inflammation as Trigger and Target of Atherosclerosis In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 15-27.: http://10.1007/978-3-319-66224-4
  • von zur Mühlen C, Choudhury RP: Cardiac Imaging of Platelets and Inflammation In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 1-13.: http://10.1007/978-3-319-66224-4
  • Willecke F, Nagareddy PR, Murphy AJ: Mechanisms of Platelet Activation in Diabetes Mellitus In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 137-152.: http://10.1007/978-3-319-66224-4
  • Wolf D, Gerhardt T, Ley K: Vaccination to Prevent Cardiovascular Disease In: Zirlik A, Bode C, Gawaz M (Hrsg.): Platelets, Haemostasis and Inflammation Springer International Publishing, 2017; 29-52.: http://10.1007/978-3-319-66224-4
  • Zirlik A, Bode C, Gawaz M: Microparticles: surrogate markers and promotors of cardiovascular diseases In: Platelets, Haemostasis and Inflammation Springer, 2017. (in Druck)
Fallbeispiele:
  • Rotta Detto Loria J, Rawluk J, Krauss T, Bode C, Moser M, Helbing T: Acute transmural myocardial infarction by coronary embolism in a patient with JAK2 V617F-positive essential thrombocythemia. Hamostaseologie, 2017. : http://dx.doi.org/10.5482/HAMO-16-12-0046 (in Druck)
  • Stachon P, Kalbhenn J, Walterspacher S, Bode C, Staudacher D: Überleben mit guter Neurologie nach Beinahe-Ertrinken durch ECMO-Therapie und therapeutischer Hypothermie trotz 20-minütiger Anoxie und 16-stündiger Hypoxie DMW-Deutsche Medizinische Wochenschrift, 2017; 142: 596-600.
Kurzbeiträge / short communications:
  • Herr N, Dürschmied D: Lungenembolie – aktuelle Therapie und ihre Wirkung im Freiburger Register UHZ Aktuell, 2017; 19: 6-7.
Konferenzbeiträge:
  • Brado J, Dechant MJ, Menza M, Komancsek A, Geiger J, Stiller B, Foell D, Jung BA, Bode C, Odening KE: Phase contrast MRI reveals regional, transmural, and apico-basal dispersion of mechanical dysfunction in LQTS patients. 2017 (“38th Annual Scientific Sessions of the Heart Rhythm Society”, Mai 2017, Chicago, USA. / “83th Annual Meeting of the German Society of Cardiology”, April 2017, Mannheim.).
  • Castiglione A, Hornyik T, Franke G, Perez-Feliz S, Bősze Z, Koren G, Varró A, Brunner M, Bode C, Baczkó I, Odening KE: Genotype-specific beneficial QT-shortening effects of docosahexaenoic acid in transgenic LQT2, LQT5 and LQT2-5 rabbit models. 2017 (41th Meeting of the ESC Working Group on Cardiac Cellular Electrophysiology, Wien, Juni 2017).
  • Hornyik T, Castiglione A, Franke G, Perez-Feliz S, Major P, Hiripi L, Koren G, Bosze Z, Varro A, Brunner M, Bode C, Baczko I, Odening KE: Transgenic LQT2, LQT5 and LQT2-5 rabbit models with decreased repolarization reserve as novel tools for more reliable indentification of pro-arrhythmic markers. 2017 (“83th Annual Meeting of the German Society of Cardiology”, April 2017, Mannheim).
  • Kreifels P, Franke G, Perez-Feliz S, Bodi I, Bode C, Odening KE: Good feeling, bad heart? – Ambiguity of "cuddling" hormone oxytocin in therapeutic use due to repolarization prolonging effects in the context of anti-psychotic and anti-depressant drug-treatment. 2017 (41th Meeting of the ESC Working Group on Cardiac Cellular Electrophysiology, Wien, Juni 2017.).
  • Krieger K, Steinfurt J, Lenz C, Bruch L, Keweloh B: Successful catheter ablation of epicardial substrate in a Brugada syndrome patient with spontaneous coved-type ECG and out-of-hospital cardiac arrest: initial short-term follow-up Clin Res Cardiol, 2017; 106 Suppl. 2. (download: http://dgk.org/kongress_programme/ht2017/aP464.html)
  • Lahrouchi N, Tadros R, Mizusawa Y, Postema PG, Yoshinaga M, Behr ER, Rydberg A, van den Berg MP, Robyns T, Roden DM, Brugada J, Salling Olesen M, Tfelt-Hansen J, Skinner JR, Antzelevich C, Odening KE, Borggrefe M, Loeys B, Lubitz SA, Sarquella-Brugada G, Veldink JH, Al-Chalabi A, Andersen PM, Müller-Nurasyid M, Cusi D, Galan P, Werge T, Ribasés M, Lichtner P, Meitinger T, Brugada R, Makita N, Priori SG, Guicheney P, Kääb S, Schulze-Bahr E, Schwartz PJ, Probst V, Ohno S, Wilde AA, Tanck MWT, Bezzina CR: Multinational genome-wide association study in long QT syndrome identifies a role for common genetic variation in disease susceptibility and points to a polygenic architecture in mutation-negative cases. 2017 (. “38th Annual Scientific Sessions of the Heart Rhythm Society”, Mai 2017, Chicago, USA.).
  • Odening KE, Bodi I, Rieke R, Franke G, Ryan de Medeiros A, Perez-Feliz S, zur Hausen A, Jolivet G, Bode C, Brunner M: Electrico-Mechanical Remodeling in Transgenic Short QT 1 Rabbits. 2017 (“38th Annual Scientific Sessions of the Heart Rhythm Society”, Mai 2017, Chicago, USA. / “83th Annual Meeting of the German Society of Cardiology”, April 2017, Mannheim.).
  • Staudacher D, Duerschmied D, Biever P, Benk C, Bode C, Wengenmayer T: P5293Predicting survival in patients on venoarterial extracorporeal membrane oxygenation therapy using point of care biomarkers Eur Heart J, 2017; 38.
  • Staudacher D, Duerschmied D, Graf E, Chiabudini M, Benk C, Bode C, Wengenmayer T: Development and external validation of a prognostic model for hospital survival in patients on venoarterial extracorporeal membrane oxygenation therapy using point of care biomarkers The PREDICT VA-ECMO score Med Klin-intensivmed, 2017; 112: 395-395.
Sonstige Publikationen:
  • Supady A, Duerschmied D, Bode C, Staudacher DL: Means for Transport in Patients after Remote Extracorporeal Membrane Oxygenation Implantation Air Medical Journal, 2017.

Besondere wissenschaftliche Aktivitäten

Preise / Ehrungen:
  • Dr. Constantin von zur Mühlen: Rudolf-Thauer Posterpreis, DGK Jahreskonferenz, Deutsche Gesellschaft für Kardiologie, 14.04.2007.
  • Dr. Constantin von zur Mühlen: W.P. Harvey-Preis, Eröffnung Akademisches Jahr, Stiftung Just, 24.10.2007.
  • Dr. Daniel Dürschmied: Max-Ratschow-Preis, DGA Mannheim, 24.09.2008.
  • Dr. Katja Odening: Estradiol Pro-Arrhythmic and Progesterone Anti-Arrhythmic Effects in Transgenic Rabbits with Long QT Syndrome 2 are Mediated via Modifications of Cardiac Repolarization and Opposing Effects on Vulnerability to EAD Formation, Northwestern Cardiovascular Young “Investigators Award” 2009 in Chicago, 01.01.2009.
  • Dr. Schwarz: Best-Abstract Preis, Jahrestagung GTH, 01.02.2007.
  • Dr. Sebastian Grundmann: ADUMED Forschungspreis, Herbsttagung DGK, Deutsche Gesellschaft für Kardiologie, 08.10.2007.
  • Dr. Zirlik: MSD Preis Arteriosklerose / Hypertonie 2007, MSD, 08.12.2007.
  • PD Dr. Marc Kollum, Prof. Dr. Dr. Manfred Zehender: Andreas Grüntzig Forschungspreis für "Intra-indiviual Head-to-Head Comparison of Sirolimus- and Paclitaxel-Eluting Stents for Coronary Revascularization. A Randomized, Multi-Center Trail.", Deutsche Gesellschaft für Kardiologie, 01.04.2010.
Veranstaltung:
  • Dr. T. Grumann: Press highlight: The role played by drug-eluting stents in reducing mortality in AMI, Congress of the European Society of Cardiology, seit 02.09.2008.

Abschlussarbeiten