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 Forschungsbericht für das Jahr 2017

Department Innere Medizin

Klinik für Innere Medizin II

Hugstetterstrasse 55
79106 Freiburg
Tel: +49-761-270-34040
https://www.uniklinik-freiburg.de/medizin2.html


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Professor Dr. Hubert Blum
  • PD Dr. Thomas Baumert
  • Prof. Dr. Winfried V. Kern
  • Prof. Dr. Wolfgang Kreisel
  • Prof. Dr. Michael Nassal
  • Prof. Dr. Jens Rasenack
  • Prof. Dr. Hans-Christian Spangenberg
  • Prof. Dr. Robert Thimme
  • Dr. Henning Schwacha
Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Aguila-Arcos S, Alvarez-Rodriguez I, Garaiyurrebaso O, Garbisu C, Grohmann E, Alkorta I: Biofilm-Forming Clinical Staphylococcus Isolates Harbor Horizontal Transfer and Antibiotic Resistance Genes. Front Microbiol, 2017; 8: 2018-2018. : http://dx.doi.org/10.3389/fmicb.2017.02018
  • Anjum R, Grohmann E, Krakat N: Anaerobic digestion of nitrogen rich poultry manure: Impact of thermophilic biogas process on metal release and microbial resistances Chemosphere, 2017; 168: 1637-1647.
  • Bausch B, Schiavi F, Ni Y, Welander J, Patocs A, Ngeow J, Wellner U, Malinoc A, Taschin E, Barbon G, Lanza V, Soderkvist P, Stenman A, Larsson C, Svahn F, Chen JL, Marquard J, Fraenkel M, Walter MA, Peczkowska M, Prejbisz A, Jarzab B, Hasse-Lazar K, Petersenn S, Moeller LC, Meyer A, Reisch N, Trupka A, Brase C, Galiano M, Preuss SF, Kwok P, Lendvai N, Berisha G, Makay O, Boedeker CC, Weryha G, Racz K, Januszewicz A, Walz MK, Gimm O, Opocher G, Eng C, Neumann HP: Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. JAMA Oncol, 2017; 3 (9): 1204-1212. : http://dx.doi.org/10.1001/jamaoncol.2017.0223
  • Bengsch B, Ohtani T, Herati RS, Bovenschen N, Chang KM, Wherry EJ: Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. J Immunol Methods, 2017. : http://dx.doi.org/10.1016/j.jim.2017.03.009 (in Druck)
  • Bettinger D, Spode R, Glaser N, Buettner N, Boettler T, Neumann-Haefelin C, Brunner TB, Gkika E, Maruschke L, Thimme R, Schultheiss M: Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience. Bmc Gastroenterol, 2017; 17 (1): 98-98. : http://dx.doi.org/10.1186/s12876-017-0656-z
  • Blum HE: The human microbiome. Adv Med Sci-poland, 2017; 62 (2): 414-420. : http://dx.doi.org/10.1016/j.advms.2017.04.005
  • Borde JP, Dobler G, Rieg S: [Update on Tick-Borne Diseases in Germany]. Deut Med Wochenschr, 2017; 142 (11): 805-810. : http://dx.doi.org/10.1055/s-0042-122468
  • Borde JP, Zange S, Antwerpen MH, Georgi E, von Buttlar H, Kern WV, Rieg S: Five cases of vector-borne Francisella tularensis holarctica infections in south-western Germany and genetic diversity. Ticks Tick-borne Dis, 2017; 8 (5): 808-812. : http://dx.doi.org/10.1016/j.ttbdis.2017.06.009
  • Bramlage P, Lanzinger S, Rathmann W, Gillessen A, Scheper N, Schmid SM, Kaltheuner M, Seufert J, Danne T, Holl RW: Dyslipidaemia and its treatment in patients with type 2 diabetes: A joint analysis of the German DIVE and DPV registries. Diabetes Obes Metab, 2017; 19: 61-69.
  • Brass V, Thimme R, Will U: [Endoscopic Ultrasound-Guided Fine Needle Aspiration]. Deut Med Wochenschr, 2017; 142 (5): 371-375. : http://dx.doi.org/10.1055/s-0043-100121
  • Cahyadi O, Bauder M, Meier B, Caca K, Schmidt A: Effectiveness of TC-325 (Hemospray) for treatment of diffuse or refractory upper gastrointestinal bleeding - a single center experience. Endosc Int Open, 2017; 5 (11): E1159-E1164. : http://dx.doi.org/10.1055/s-0043-118794
  • de With K, Wilke K, Forst G, Kramme E, Kern WV: [Hospital Antibiotic Stewardship - New Guidelines and New Findings]. Deut Med Wochenschr, 2017; 142 (3): 177-182. : http://dx.doi.org/10.1055/s-0042-121745
  • Fischer J, Weber AN, Bohm S, Dickhofer S, El Maadidi S, Deichsel D, Knop V, Klinker H, Moller B, Rasenack J, Wang L, Sharma M, Hinrichsen H, Spengler U, Buggisch P, Sarrazin C, Pawlita M, Waterboer T, Wiese M, Probst-Muller E, Malinverni R, Bochud PY, Gardiner CM, O'Farrelly C, Berg T: Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection. Gut, 2017; 66 (10): 1829-1837. : http://dx.doi.org/10.1136/gutjnl-2015-310239
  • Forst G, de With K, Weber N, Borde J, Querbach C, Kleideiter J, Seifert C, Hagel S, Ambrosch A, Lobermann M, Schroder P, Steib-Bauert M, Kern WV: Validation of adapted daily dose definitions for hospital antibacterial drug use evaluation: a multicentre study. J Antimicrob Chemoth, 2017; 72 (10): 2931-2937. : http://dx.doi.org/10.1093/jac/dkx244
  • Gajer M, Dornbrack K, Rosler C, Schmid B, Beck J, Nassal M: Few basepairing-independent motifs in the apical half of the avian HBV epsilon RNA stem-loop determine site-specific initiation of protein-priming. Sci Rep-uk, 2017; 7 (1): 7120-7120. : http://dx.doi.org/10.1038/s41598-017-07657-z
  • Garaiyurrebaso O, Garbisu C, Blanco F, Lanzen A, Martin I, Epelde L, Becerril JM, Jechalke S, Smalla K, Grohmann E, Alkorta I: Long-term effects of aided phytostabilisation on microbial communities of metal-contaminated mine soil. Fems Microbiol Ecol, 2017; 93 (3): fiw252. : http://dx.doi.org/10.1093/femsec/fiw252
  • Garbisu C, Garaiyurrebaso O, Epelde L, Grohmann E, Alkorta I: Plasmid-Mediated Bioaugmentation for the Bioremediation of Contaminated Soils. Front Microbiol, 2017; 8: 1966-1966. : http://dx.doi.org/10.3389/fmicb.2017.01966
  • Geier A, Macias RI, Bettinger D, Weiss J, Bantel H, Jahn D, Al-Abdulla R, Marin JJ: The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma. Oncotarget, 2017; 8 (9): 15846-15857. : http://dx.doi.org/10.18632/oncotarget.15029
  • Gkika E, Schultheiss M, Bettinger D, Maruschke L, Neeff HP, Schulenburg M, Adebahr S, Kirste S, Nestle U, Thimme R, Grosu AL, Brunner TB: Excellent local control and tolerance profile after stereotactic body radiotherapy of advanced hepatocellular carcinoma. Radiat Oncol, 2017; 12 (1): 116-116. : http://dx.doi.org/10.1186/s13014-017-0851-7
  • Gladstone BP, Cona A, Shamsrizi P, Vilken T, Kern WV, Malek N, Tacconelli E: Antimicrobial resistance rates in gram-positive bacteria do not drive glycopeptides use. Plos One, 2017; 12 (7): e0181358-e0181358. : http://dx.doi.org/10.1371/journal.pone.0181358
  • Glaser C, Rieg S, Wiech T, Scholz C, Endres D, Stich O, Hasselblatt P, Geissdorfer W, Bogdan C, Serr A, Hacker G, Voll RE, Thiel J, Venhoff N: Whipple's disease mimicking rheumatoid arthritis can cause misdiagnosis and treatment failure. Orphanet J Rare Dis, 2017; 12 (1): 99-99. : http://dx.doi.org/10.1186/s13023-017-0630-4
  • Glatz T, Marjanovic G, Lulemann B, Hipp J, Theodor Hopt U, Fischer A, Richter-Schrag HJ, Hoeppner J: Management and outcome of esophageal stenting for spontaneous esophageal perforations. Dis Esophagus, 2017; 30 (3): 1-6.
  • Harak C, Meyrath M, Romero-Brey I, Schenk C, Gondeau C, Schult P, Esser-Nobis K, Saeed M, Neddermann P, Schnitzler P, Gotthardt D, Perez-Del-Pulgar S, Neumann-Haefelin C, Thimme R, Meuleman P, Florian WR, De Francesco R, Rice CM, Bartenschlager R, Lohmann V: Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture. Nat Microbiol, 2017; 2: 17012-17012. : http://dx.doi.org/10.1038/nmicrobiol.2017.12
  • Herati RS, Muselman A, Vella L, Bengsch B, Parkhouse K, Del Alcazar D, Kotzin J, Doyle SA, Tebas P, Hensley SE, Su LF, Schmader KE, Wherry EJ: Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells. Sci Immunol, 2017; 2 (8): eaag2152. : http://dx.doi.org/10.1126/sciimmunol.aag2152
  • Hoeppner J, Glatz T, Claus R, Fischer A, Kraywinkel K, Brunner T: [Esophageal Adenocarcinoma - Appraisal of a Rapidly Increasing Disease]. Deut Med Wochenschr, 2017; 142 (19): 1453-1460. : http://dx.doi.org/10.1055/s-0043-115777
  • Hos NJ, Jazmati N, Stefanik D, Hellmich M, AlSael H, Kern WV, Rieg S, Wisplinghoff H, Seifert H, Kaasch AJ: Determining vancomycin Etest MICs in patients with MRSA bloodstream infection does not support switching antimicrobials. J Infection, 2017; 74 (3): 248-259. : http://dx.doi.org/10.1016/j.jinf.2016.12.007
  • Howell J, Pinato DJ, Ramaswami R, Bettinger D, Arizumi T, Ferrari C, Yen C, Gibbin A, Burlone ME, Guaschino G, Sellers L, Black J, Pirisi M, Kudo M, Thimme R, Park JW, Sharma R: On-target sorafenib toxicity predicts improved survival in hepatocellular carcinoma: a multi-centre, prospective study. Aliment Pharm Ther, 2017; 45 (8): 1146-1155. : http://dx.doi.org/10.1111/apt.13977
  • Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu X, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ: T-cell invigoration to tumour burden ratio associated with anti-PD-1 response. Nature, 2017; 545 (7652): 60-65. : http://dx.doi.org/10.1038/nature22079
  • Jabbour S, Seufert J, Scheen A, Bailey CJ, Karup C, Langkilde AM: Dapagliflozin in patients with type 2 diabetes mellitus: A pooled analysis of safety data from phase IIb/III clinical trials. Diabetes Obes Metab, 2017. : http://dx.doi.org/10.1111/dom.13124 (in Druck)
  • Joost I, Kaasch A, Pausch C, Peyerl-Hoffmann G, Schneider C, Voll RE, Seifert H, Kern WV, Rieg S: Staphylococcus aureus bacteremia in patients with rheumatoid arthritis - Data from the prospective INSTINCT cohort. J Infection, 2017; 74 (6): 575-584. : http://dx.doi.org/10.1016/j.jinf.2017.03.003
  • Knoop RF, Richer-Schrag HJ, Thimme R, Fischer A: Use of the full-thickness resection device (FTRD) to prevent bleeding after colonic polypectomy in a patient with a left ventricular assist device. Endosc Int Open, 2017; 5 (8): E749-E753. : http://dx.doi.org/10.1055/s-0043-111593
  • Knoop RF, Thimme R, Fischer A: Successful two-sided sponge pull-through treatment of anastomotic leakage following pancreaticoduodenectomy with pancreaticogastrostomy. Endoscopy, 2017; 49 (10): 1010-1012. : http://dx.doi.org/10.1055/s-0043-113552
  • Kohler V, Probst I, Aufschnaiter A, Buttner S, Schaden L, Rechberger GN, Koraimann G, Grohmann E, Keller W: Conjugative type IV secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM. Plasmid, 2017; 91: 9-18. : http://dx.doi.org/10.1016/j.plasmid.2017.02.002
  • Krawczyk M, Rau M, Grunhage F, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Geier A, Lammert F: The ABCB4 p.T175A variant as potential modulator of hepatic fibrosis in patients with chronic liver diseases: Looking beyond the cholestatic realm. Hepatology, 2017; 66 (2): 666-667. : http://dx.doi.org/10.1002/hep.29100
  • Kreisel W, Ruf G, Salm R, Lazaro A, Bengsch B, Globig AM, Fisch P, Lassmann S, Schmitt-Graeff A: Protein-losing pseudomembranous colitis with cap polyposis-like features. World J Gastroentero, 2017; 23 (16): 3003-3010. : http://dx.doi.org/10.3748/wjg.v23.i16.3003
  • Kurachi M, Kurachi J, Chen Z, Johnson J, Khan O, Bengsch B, Stelekati E, Attanasio J, McLane LM, Tomura M, Ueha S, Wherry EJ: Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function. Nat Protoc, 2017; 12 (9): 1980-1998. : http://dx.doi.org/10.1038/nprot.2017.083
  • Lauber C, Seitz S, Mattei S, Suh A, Beck J, Herstein J, Borold J, Salzburger W, Kaderali L, Briggs JAG, Bartenschlager R: Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses. Cell Host Microbe, 2017; 22 (3): 387-399.e6. : http://dx.doi.org/10.1016/j.chom.2017.07.019
  • Laubner K, Seufert J: [Cardiovascular Effects of Antidiabetic Therapies]. Deut Med Wochenschr, 2017; 142 (10): 737-745. : http://dx.doi.org/10.1055/s-0043-100564
  • Laverde D, Probst I, Romero-Saavedra F, Kropec A, Wobser D, Keller W, Grohmann E, Huebner J: Targeting Type IV Secretion System Proteins to Combat Multidrug-Resistant J Infect Dis, 2017; 215 (12): 1836-1845. : http://dx.doi.org/10.1093/infdis/jix227
  • Le Guillou-Guillemette H, Pivert A, Bouthry E, Henquell C, Petsaris O, Ducancelle A, Veillon P, Vallet S, Alain S, Thibault V, Abravanel F, Rosenberg AA, Andre-Garnier E, Bour JB, Baazia Y, Trimoulet P, Andre P, Gaudy-Graffin C, Bettinger D, Larrat S, Signori-Schmuck A, Saoudin H, Pozzetto B, Lagathu G, Minjolle-Cha S, Stoll-Keller F, Pawlotsky JM, Izopet J, Payan C, Lunel-Fabiani F, Lemaire C: Natural non-homologous recombination led to the emergence of a duplicated V3-NS5A region in HCV-1b strains associated with hepatocellular carcinoma. Plos One, 2017; 12 (4): e0174651-e0174651. : http://dx.doi.org/10.1371/journal.pone.0174651
  • Lehmann C, Berner R, Bogner JR, Cornely OA, de With K, Herold S, Kern WV, Lemmen S, Pletz MW, Ruf B, Salzberger B, Stellbrink HJ, Suttorp N, Ullmann AJ, Fatkenheuer G, Jung N: The "Choosing Wisely" initiative in infectious diseases. Infection, 2017; 45 (3): 263-268. : http://dx.doi.org/10.1007/s15010-017-0997-0
  • Lyons SK, Hermann JM, Miller KM, Hofer SE, Foster NC, Rami-Merhar BM, Aleppo G, Seufert J, DiMeglio LA, Danne T, Maahs DM, Holl RW: Use of Adjuvant Pharmacotherapy in Type 1 Diabetes: International Comparison of 49,996 Individuals in the Prospective Diabetes Follow-up and T1D Exchange Registries. Diabetes Care, 2017; 40 (10): e139-e140. : http://dx.doi.org/10.2337/dc17-0403
  • Mauricio D, Meneghini L, Seufert J, Liao L, Wang H, Tong L, Cali A, Stella P, Carita P, Khunti K: Glycaemic control and hypoglycaemia burden in patients with type 2 diabetes initiating basal insulin in Europe and the USA. Diabetes Obes Metab, 2017; 19 (8): 1155-1164. : http://dx.doi.org/10.1111/dom.12927
  • Meier B, Caca K, Fischer A, Schmidt A: Endoscopic management of colorectal adenomas. Ann Gastroenterol, 2017; 30 (6): 592-597. : http://dx.doi.org/10.20524/aog.2017.0193
  • Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Golz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV: Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission. Int J Antimicrob Ag, 2017; 49 (2): 239-242. : http://dx.doi.org/10.1016/j.ijantimicag.2016.10.013
  • Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Golz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV: Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission. Diagn Micr Infec Dis, 2017; 87 (1): 71-73. : http://dx.doi.org/10.1016/j.diagmicrobio.2016.09.012
  • Mischnik A, Baumert P, Hamprecht A, Rohde AM, Peter S, Feihl S, Knobloch J, Golz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV: In vitro susceptibility to 19 agents other than beta-lactams among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission. J Antimicrob Chemoth, 2017; 72 (5): 1359-1363. : http://dx.doi.org/10.1093/jac/dkw577
  • Mischnik A, Kern WV, Thimme R: [Pyogenic liver abscess: Changes of Organisms and Consequences for Diagnosis and Therapy]. Deut Med Wochenschr, 2017; 142 (14): 1067-1074. : http://dx.doi.org/10.1055/s-0043-100540
  • Mollaiyan A, Bettinger D, Rossle M: The underdilation of nitinol stents at TIPS implantation: Solution or illusion? Eur J Radiol, 2017; 89: 123-128. : http://dx.doi.org/10.1016/j.ejrad.2017.01.032
  • Monasterio C, Schmitt-Graff A, Pohl M, Truschel T, Warnatz K, Kreisel W, Thimme R, Hasselblatt P: Fatal ulcerative enteritis of the small intestine in a patient with ulcerative colitis treated with vedolizumab. Z Gastroenterol, 2017; 55 (10): 1014-1020. : http://dx.doi.org/10.1055/s-0043-111805
  • Nassal M: Chronic hepatitis B: divide and conquer? Gut, 2017. : http://dx.doi.org/10.1136/gutjnl-2017-314255 (in Druck)
  • Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, Shaw W, Law G, Desai M, Matthews DR: Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. New Engl J Med, 2017; 377 (7): 644-657. : http://dx.doi.org/10.1056/NEJMoa1611925
  • Perakakis N, Triantafyllou GA, Fernandez-Real JM, Huh JY, Park KH, Seufert J, Mantzoros CS: Physiology and role of irisin in glucose homeostasis. Nat Rev Endocrinol, 2017; 13 (6): 324-337. : http://dx.doi.org/10.1038/nrendo.2016.221
  • Petersen BS, August D, Abt R, Alddafari M, Atarod L, Baris S, Bhavsar H, Brinkert F, Buchta M, Bulashevska A, Chee R, Cordeiro AI, Dara N, Duckers G, Elmarsafy A, Frede N, Galal N, Gerner P, Glocker EO, Goldacker S, Hammermann J, Hasselblatt P, Havlicekova Z, Hubscher K, Jesenak M, Karaca NE, Karakoc-Aydiner E, Kharaghani MM, Kilic SS, Kiykim A, Klein C, Klemann C, Kobbe R, Kotlarz D, Laass MW, Leahy TR, Mesdaghi M, Mitton S, Neves JF, Ozturk B, Pereira LF, Rohr J, Restrepo JLR, Ruzaike G, Saleh N, Seneviratne S, Senol E, Speckmann C, Tegtmeyer D, Thankam P, van der Werff Ten Bosch J, von Bernuth H, Zeissig S, Zeissig Y, Franke A, Grimbacher B: Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and Chronic Diarrhea. Inflamm Bowel Dis, 2017; 23 (12): 2109-2120. : http://dx.doi.org/10.1097/MIB.0000000000001235
  • Pichler C, Buchsel M, Rossen JW, Vavra M, Reuter S, Kern WV, Thimme R, Mischnik A: First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016. New Microbes New Infect, 2017; 17: 77-80. : http://dx.doi.org/10.1016/j.nmni.2017.02.006
  • Pinato DJ, Sharma R, Allara E, Yen C, Arizumi T, Kubota K, Bettinger D, Jang JW, Smirne C, Kim YW, Kudo M, Howell J, Ramaswami R, Burlone ME, Guerra V, Thimme R, Ishizuka M, Stebbing J, Pirisi M, Carr BI: The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma. J Hepatol, 2017; 66 (2): 338-346. : http://dx.doi.org/10.1016/j.jhep.2016.09.008
  • Pinato DJ, Yen C, Bettinger D, Ramaswami R, Arizumi T, Ward C, Pirisi M, Burlone ME, Thimme R, Kudo M, Sharma R: The albumin-bilirubin grade improves hepatic reserve estimation post-sorafenib failure: implications for drug development. Aliment Pharm Ther, 2017; 45 (5): 714-722. : http://dx.doi.org/10.1111/apt.13904
  • Pollmann J, Gotz JJ, Rupp D, Strauss O, Granzin M, Grunvogel O, Mutz P, Kramer C, Lasitschka F, Lohmann V, Bjorkstrom NK, Thimme R, Bartenschlager R, Cerwenka A: Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis. J Hepatol, 2017. : http://dx.doi.org/10.1016/j.jhep.2017.10.021 (in Druck)
  • Reinauer C, Bollow E, Frohlich-Reiterer E, Laubner K, Bergis D, Schofl C, Kempe HP, Hummel M, Hennes P, Gollisch K, Haberland H, Datz N, Meissner T, Holl RW: Polycystic Ovary Syndrome (PCOS) in Juvenile and Adult Type 1 Diabetes in a German/Austrian Cohort. Exp Clin Endocr Diab, 2017; 125 (10): 661-668. : http://dx.doi.org/10.1055/s-0043-104701
  • Rieg S, Joost I, Weiß V, Peyerl-Hoffmann G, Schneider C, Hellmich M, Seifert H, Kern WV, Kaasch A: Combination antimicrobial therapy in patients with Staphylococcus aureus bacteraemia-a post hoc analysis in 964 prospectively evaluated patients Clin Microbiol Infec, 2017; 23 (6): 406.e1-406.e8.
  • Rieg S, Kaasch AJ: [Controversies in Treatment of Severe Staphylococcus Infections]. Deut Med Wochenschr, 2017; 142 (7): 493-498. : http://dx.doi.org/10.1055/s-0042-120983
  • Ruffing U, Alabi A, Kazimoto T, Vubil DC, Akulenko R, Abdulla S, Alonso P, Bischoff M, Germann A, Grobusch MP, Helms V, Hoffmann J, Kern WV, Kremsner PG, Mandomando I, Mellmann A, Peters G, Schaumburg F, Schubert S, Strauss L, Tanner M, Briesen HV, Wende L, Muller LV, Herrmann M: Community-Associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic Correlation Study. Sci Rep-uk, 2017; 7 (1): 154-154. : http://dx.doi.org/10.1038/s41598-017-00214-8
  • Schaffner D, von Elverfeldt D, Deibert P, Lazaro A, Merfort I, Lutz L, Neubauer J, Baumstark MW, Kreisel W, Reichardt W: Phase-contrast MR flow imaging: A tool to determine hepatic hemodynamics in rats with a healthy, fibrotic, or cirrhotic liver. J Magn Reson Imaging, 2017; 46 (5): 1526-1534. : http://dx.doi.org/10.1002/jmri.25677
  • Schmidt A, Beyna T, Schumacher B, Meining A, Richter-Schrag HJ, Messmann H, Neuhaus H, Albers D, Birk M, Thimme R, Probst A, Faehndrich M, Frieling T, Goetz M, Riecken B, Caca K: Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications. Gut, 2017. : http://dx.doi.org/10.1136/gutjnl-2016-313677 (in Druck)
  • Schreiner S, Nassal M: A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation-and Beyond? Viruses-basel, 2017; 9 (5): pii: E125. : http://dx.doi.org/10.3390/v9050125
  • Schultheiss UT, Daya N, Grams ME, Seufert J, Steffes M, Coresh J, Selvin E, Kottgen A: Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: the Atherosclerosis Risk in Communities study. Nephrol Dial Transpl, 2017; 32 (11): 1874-1881. : http://dx.doi.org/10.1093/ndt/gfw301
  • Schuster S, Vavra M, Schweigger T, Rossen JWA, Matsumura Y, Kern WV: Contribution of AcrAB-TolC to multidrug resistance in an escherichia coli sequence type 131 isolate. Int J Antimicrob Ag, 2017; 50 (3): 477-481. : http://dx.doi.org/10.1016/j.ijantimicag.2017.03.023
  • Seufert J: Incretins and Their Endocrine and Metabolic Functions. Endocr Dev, 2017; 32: 38-48. : http://dx.doi.org/10.1159/000475730
  • Siegmund T, Pfohl M, Forst T, Pscherer S, Bramlage P, Foersch J, Borck A, Seufert J: Titration of basal insulin or immediate addition of rapid acting insulin in patients not at target using basal insulin supported oral antidiabetic treatment - A prospective observational study in 2202 patients. Diabetes & Metabolic Syndrom, 2017; 11 (1): 51-57.
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