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 Forschungsbericht für das Jahr 2017

Department Chirurgie

Klinik für Thoraxchirurgie

Hugstetterstrasse 55
79106 Freiburg
Tel: +49 761 270 2457 Fax: +49 761 270 2499
http://www.uniklinik-freiburg.de/thoraxchirurgie


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Lungenkarzinom
  • Lungentransplantation
  • Pleuramesotheliom
  • Laser-Chirurgie
  • Lungenmetastasen

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Caudron-Herger M, Diederichs S: Mitochondrial mutations in human cancer: Curation of translation. Rna Biol, 2017. : http://dx.doi.org/10.1080/15476286.2017.1373239 (in Druck)
  • Das K, Eisel D, Lenkl C, Goyal A, Diederichs S, Dickes E, Osen W, Eichmuller SB: Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system. Plos One, 2017; 12 (3): e0174077-e0174077. : http://dx.doi.org/10.1371/journal.pone.0174077
  • Fricke A, Bannasch H, Klein HF, Wiesemann S, Samson-Himmelstjerna P, Passlick B, Beyersdorf F, Hoeppner J, Penna V, Eisenhardt SU, Stark BG, Koulaxouzidis G: Pedicled and free flaps for intrathoracic fistula management. Eur J Cardio-thorac, 2017; 52 (6): 1211-1217. : http://dx.doi.org/10.1093/ejcts/ezx216
  • Goyal A, Fiskin E, Gutschner T, Polycarpou-Schwarz M, Gross M, Neugebauer J, Gandhi M, Caudron-Herger M, Benes V, Diederichs S: A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression. Nucleic Acids Res, 2017; 45 (21): 12496-12508. : http://dx.doi.org/10.1093/nar/gkx952
  • Goyal A, Myacheva K, Gross M, Klingenberg M, Duran Arque B, Diederichs S: Challenges of CRISPR/Cas9 applications for long non-coding RNA genes. Nucleic Acids Res, 2017; 45 (3) (online): e12-e12. : http://dx.doi.org/10.1093/nar/gkw883
  • Haderk F, Schulz R, Iskar M, Cid LL, Worst T, Willmund KV, Schulz A, Warnken U, Seiler J, Benner A, Nessling M, Zenz T, Gobel M, Durig J, Diederichs S, Paggetti J, Moussay E, Stilgenbauer S, Zapatka M, Lichter P, Seiffert M: Tumor-derived exosomes modulate PD-L1 expression in monocytes. Sci Immunol, 2017; 2 (13) (online): eaah5509. : http://dx.doi.org/10.1126/sciimmunol.aah5509
  • Mecklenburg I, Sienel W, Schmid S, Passlick B, Kufer P: A Threshold of Systemic MAGE-A Gene Expression Predicting Survival in Resected Non-Small Cell Lung Cancer. Clin Cancer Res, 2017; 23 (5): 1213-1219. : http://dx.doi.org/10.1158/1078-0432.CCR-16-0557
  • Moneke I, Kaifi JT, Kloeser R, Samson P, Haager B, Wiesemann S, Diederichs S, Passlick B: Pulmonary metastasectomy for thyroid cancer as salvage therapy for radioactive iodine-refractory metastases. Eur J Cardio-thorac, 2017. : http://dx.doi.org/10.1093/ejcts/ezx367 (in Druck)
  • Notzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Gross M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S: The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells. Sci Rep-uk, 2017; 7 (1): 2265-2265. : http://dx.doi.org/10.1038/s41598-017-02357-0
  • Seiler J, Breinig M, Caudron-Herger M, Polycarpou-Schwarz M, Boutros M, Diederichs S: The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance. Nucleic Acids Res, 2017; 45 (9): 5458-5469. : http://dx.doi.org/10.1093/nar/gkx076
  • Soares RJ, Maglieri G, Gutschner T, Diederichs S, Lund AH, Nielsen BS, Holmstrom K: Evaluation of fluorescence in situ hybridization techniques to study long non-coding RNA expression in cultured cells. Nucleic Acids Res, 2017. : http://dx.doi.org/10.1093/nar/gkx946 (in Druck)
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
  • Klingenberg M, Matsuda A, Diederichs S, Patel T: Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets. J Hepatol, 2017; 67 (3): 603-618. : http://dx.doi.org/10.1016/j.jhep.2017.04.009
  • Schmid S, Passlick B: [The Significance of Surgery for Oligometastatic and Oligoprogressive Non-small Cell Lung Cancer]. Zbl Chir, 2017; 142 (S 01): S38-S43. : http://dx.doi.org/10.1055/s-0043-115641
Sonstige Publikationen:
  • Passlick B: Editorial Zbl Chir, 2017; 142 (S01) : S10.

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten