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 Forschungsbericht für das Jahr 2017

Department Chirurgie

Klinik für Orthopädie und Unfallchirurgie

Hugstetterstrasse 55
79106 Freiburg
Tel: +49 761 270 2401 Fax: +49 761 270 2783
Email hagen.schmal@uniklinik-freiburg.de
http://www.uniklinik-freiburg.de/dot


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Norbert Südkamp, Ärztlicher Direktor
  • Prof. Dr. Hagen Schmal, Ltd. Oberarzt
  • Prof. Dr. Peter Strohm, Ltd. Oberarzt
  • Dr. Hans Brauns, Oberarzt
  • Dr. med. Martin Haag, Ärztlicher Leiter Orthopädie
  • Dr. Thorsten Hammer, Oberarzt
  • PD Dr. Peter Helwig, Oberarzt
  • Dr. Martin Jaeger, Oberarzt
  • PD Dr. Stefan Knöller, Oberarzt
  • PD Dr. Phillip Niemeyer, Funktionsoberarzt
  • Dr. Michael Peters, Oberarzt
  • Dr. Kilian Reising, Funktionsoberarzt
  • Dr. Andreas Aust
  • Dr. David Dovi-Akue
  • PD Dr. Georg Herget
  • Dr. Anja Hirschmüller
  • Dr. Gian Salzmann
  • Samuel Beck, Assistent / Gruppenleiter (m/w)
  • Sebastian Bigdon, Assistent / Gruppenleiter (m/w)
  • Dr. Frank Burgbacher, Assistent / Gruppenleiter (m/w)
  • Dr. Abdelrehim El Tayeh
  • Benjamin Erdle, Assistent / Gruppenleiter (m/w)
  • Dr. Simon Herrmann, Assistent / Gruppenleiter (m/w)
  • David C Kubosch
  • Dr. Kerstin Kuminack
  • Dr. Dirk Maier
  • Julian Mehl, Assistent / Gruppenleiter (m/w)
  • PD Dr. Alexander Mehlhorn
Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Aurich M, Hofmann GO, Best N, Rolauffs B: Induced Redifferentiation of Human Chondrocytes from Articular Cartilage Lesion in Alginate Bead Culture After Monolayer Dedifferentiation: An Alternative Cell Source for Cell-Based Therapies? Tissue Eng Part B, 2017. : http://dx.doi.org/10.1089/ten.TEA.2016.0505
  • Aurich M, Hofmann GO, Rolauffs B: Tissue engineering-relevant characteristics of ex vivo and monolayer-expanded chondrocytes from the notch versus trochlea of human knee joints. Int Orthop, 2017; 41 (11): 2327-2335. : http://dx.doi.org/10.1007/s00264-017-3615-y
  • Aurich M, Hofmann GO, Rolauffs B: Differences in type II collagen turnover of osteoarthritic human knee and ankle joints. Int Orthop, 2017; 41 (5): 999-1005. : http://dx.doi.org/10.1007/s00264-017-3414-5
  • Bayer J, Lefering R, Reinhardt S, Kuhle J, Sudkamp NP, Hammer T: Severity-dependent differences in early management of thoracic trauma in severely injured patients - Analysis based on the TraumaRegister DGU(R). Scand J Trauma Resus, 2017; 25 (1): 10-10. : http://dx.doi.org/10.1186/s13049-017-0354-4
  • Bayer J, Lefering R, Reinhardt S, Kuhle J, Zwingmann J, Sudkamp NP, Hammer T: Thoracic trauma severity contributes to differences in intensive care therapy and mortality of severely injured patients: analysis based on the TraumaRegister DGU(R). World J Emerg Surg, 2017; 12: 43-43. : http://dx.doi.org/10.1186/s13017-017-0154-1
  • Behrendt P, Feldheim M, Preusse-Prange A, Weitkamp JT, Haake M, Eglin D, Rolauffs B, Fay J, Seekamp A, Grodzinsky AJ, Kurz B: Chondrogenic potential of IL-10 in mechanically injured cartilage and cellularized collagen ACI grafts. Osteoarthr Cartilage, 2017. : http://dx.doi.org/10.1016/j.joca.2017.11.007
  • Bode G, Hammer T, Karvouniaris N, Feucht MJ, Konstantinidis L, Sudkamp NP, Hirschmuller A: Patellar tendinopathy in young elite soccer- clinical and sonographical analysis of a German elite soccer academy. Bmc Musculoskel Dis, 2017; 18 (1): 344-344. : http://dx.doi.org/10.1186/s12891-017-1690-2
  • Bohner Marc, Baroud Gamal, Bernstein Anke, Doebelin Nicola, Galea Laetitia, Hesse Bernhard, Heuberger Roman, Meille Sylvain, Michel Pascal, von Rechenberg Brigitte, Sague Jorge, Seeherman Howard: Characterization and distribution of mechanically competent mineralized tissue in micropores of beta-tricalcium phosphate bone substitutes MATERIALS TODAY, 2017; 20 (3): 106-115. : http://dx.doi.org/10.1016/j.mattod.2017.02.002
  • Eberbach H, Hohloch L, Feucht MJ, Konstantinidis L, Sudkamp NP, Zwingmann J: Operative versus conservative treatment of apophyseal avulsion fractures of the pelvis in the adolescents: a systematical review with meta-analysis of clinical outcome and return to sports. Bmc Musculoskel Dis, 2017; 18 (1): 162-162. : http://dx.doi.org/10.1186/s12891-017-1527-z
  • Erdle B, Izadpanah K, Jaeger M, Jensen P, Konstantinidis L, Zwingmann J, Sudkamp NP, Maier D: Comparative analysis of locking plate versus hook plate osteosynthesis of Neer type IIB lateral clavicle fractures. Arch Orthop Traum Su, 2017; 137 (5): 651-662. : http://dx.doi.org/10.1007/s00402-017-2645-7
  • Feucht MJ, Cotic M, Beitzel K, Baldini JF, Meidinger G, Schottle PB, Imhoff AB: A matched-pair comparison of inlay and onlay trochlear designs for patellofemoral arthroplasty: no differences in clinical outcome but less progression of osteoarthritis with inlay designs. Knee Surg Sport Tr A, 2017; 25 (9): 2784-2791. : http://dx.doi.org/10.1007/s00167-015-3733-2
  • Fuchs A, Eberbach H, Izadpanah K, Bode G, Sudkamp NP, Feucht MJ: Focal metallic inlay resurfacing prosthesis for the treatment of localized cartilage defects of the femoral condyles: a systematic review of clinical studies. Knee Surg Sport Tr A, 2017. : http://dx.doi.org/10.1007/s00167-017-4714-4
  • Hirschmuller A, Andres T, Schoch W, Baur H, Konstantinidis L, Sudkamp NP, Niemeyer P: Quadriceps Strength in Patients With Isolated Cartilage Defects of the Knee: Results of Isokinetic Strength Measurements and Their Correlation With Clinical and Functional Results. Orthop J Sports Med, 2017; 5 (5): 2325967117703726-2325967117703726. : http://dx.doi.org/10.1177/2325967117703726
  • Hirschmuller A, Steffen K, Fassbender K, Clarsen B, Leonhard R, Konstantinidis L, Sudkamp NP, Kubosch EJ: German translation and content validation of the OSTRC Questionnaire on overuse injuries and health problems. Brit J Sport Med, 2017; 51: 260-263. : http://dx.doi.org/10.1136/bjsports-2016-096669
  • Izadpanah K, Hansen S, Six-Merker J, Helwig P, Sudkamp NP, Schmal H: Factors influencing treatment success of negative pressure wound therapy in patients with postoperative infections after Osteosynthetic fracture fixation. Bmc Musculoskel Dis, 2017; 18 (1): 247-247. : http://dx.doi.org/10.1186/s12891-017-1607-0
  • Jaeger M, Maier D, Izadpanah K, Sudkamp NP: [Prosthesis replacement in periprosthetic humeral fractures]. Oper Orthop Traumato, 2017; 29 (6): 492-508. : http://dx.doi.org/10.1007/s00064-017-0521-9
  • Konstantinidis L, Schmidt B, Bernstein A, Hirschmuller A, Schroter S, Sudkamp NP, Helwig P: Plate fixation of periprosthetic femur fractures: What happens to the cement mantle? P I Mech Eng H, 2017; 231 (2): 138-142. : http://dx.doi.org/10.1177/0954411916682769
  • Konstantinidis Lukas, Schmidt Benjamin, Bernstein Anke, Hirschmueller Anja, Schroeter Steffen, Suedkamp Norbert, Helwig Peter: Plate fixation of periprosthetic femur fractures: What happens to the cement mantle? PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 2017; 231 (2): 138-142. : http://dx.doi.org/10.1177/0954411916682769
  • Kubosch EJ, Heidt E, Niemeyer P, Bernstein A, Sudkamp NP, Schmal H: In-vitro chondrogenic potential of synovial stem cells and chondrocytes allocated for autologous chondrocyte implantation - a comparison : Synovial stem cells as an alternative cell source for autologous chondrocyte implantation. Int Orthop, 2017; 41 (5): 991-998. : http://dx.doi.org/10.1007/s00264-017-3400-y
  • Kubosch EJ, Kosel J, Steffen K, Konstantinidis L, Kubosch D, Sudkamp NP, Hirschmuller A: Upcoming Paralympic summer games in Rio: what did the German medical team learn from the London Games? J Sport Med Phys Fit, 2017; 57 (11): 1486-1493. : http://dx.doi.org/10.23736/S0022-4707.16.06537-3
  • Kubosch EJ, Lang GM, Furst D, Kubosch DC, Izadpanah K, Rolauffs B, Sudkamp NP, Schmal H: The Potential for Synovium-derived Stem Cells in Cartilage Repair. Curr Stem Cell Res T, 2017. : http://dx.doi.org/10.2174/1574888X12666171002111026
  • Kubosch Eva, Heidt Emanuel, Niemeyer Philipp, Bernstein Anke, Suedkamp Norbert, Schmal Hagen: In-vitro chondrogenic potential of synovial stem cells and chondrocytes allocated for autologous chondrocyte implantation - a comparison INTERNATIONAL ORTHOPAEDICS, 2017; 41 (5): 991-998. : http://dx.doi.org/10.1007/s00264-017-3400-y
  • Langenmair ER, Konstantinidis L, Sudkamp NP, Helwig P: [Prosthetic Joint Infection after Total Hip Arthroplasty: Results of an Online Questionnaire about Current Diagnostic and Therapeutic Procedures in 107 German Hospitals]. Z Orthop Unfallchir, 2017; 155 (3): 310-317. : http://dx.doi.org/10.1055/s-0043-100098
  • Lange T, Knowles BR, Herbst M, Izadpanah K, Zaitsev M: Comparative T2 and T1rho mapping of patellofemoral cartilage under in situ mechanical loading with prospective motion correction. Jmri-j Magn Reson Im, 2017; 46 (2): 452-460. : http://dx.doi.org/10.1002/jmri.25574
  • Lang G, Izadpanah K, Kubosch EJ, Maier D, Sudkamp N, Ogon P: Examination of concomitant glenohumeral pathologies in patients treated arthroscopically for calcific tendinitis of the shoulder and implications for routine diagnostic joint exploration. Bmc Musculoskel Dis, 2017; 18 (1): 476-476. : http://dx.doi.org/10.1186/s12891-017-1839-z
  • Lang G, Pestka JM, Maier D, Izadpanah K, Sudkamp N, Ogon P: Arthroscopic patellar release for treatment of chronic symptomatic patellar tendinopathy: long-term outcome and influential factors in an athletic population. Bmc Musculoskel Dis, 2017; 18 (1): 486-486. : http://dx.doi.org/10.1186/s12891-017-1851-3
  • Li Z *, Lang G *, Karfeld-Sulzer LS, Mader KT, Richards RG, Weber FE, Sammon C, Sacks H, Yayon A, Alini M, Grad S: Heterodimeric BMP-2/7 for nucleus pulposus regeneration-In vitro and ex vivo studies. J Orthopaed Res, 2017; 35 (1): 51-60. : http://dx.doi.org/10.1002/jor.23351
  • Mayr Hermann, Brandt Christian, Weig Thomas, Koehne Manuel, Bernstein Anke, Suedkamp Norbert, Hube Robert, Stoehr Amelie: Long-term Results of Arthroscopic Arthrolysis for Arthrofibrosis After Anterior Cruciate Ligament Reconstruction ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2017; 33 (2): 408-414. : http://dx.doi.org/10.1016/j.arthro.2016.07.029
  • Mayr HO, Brandt CM, Weig T, Koehne M, Bernstein A, Suedkamp NP, Hube R, Stoehr A: Long-term Results of Arthroscopic Arthrolysis for Arthrofibrosis After Anterior Cruciate Ligament Reconstruction. Arthroscopy, 2017; 33 (2): 408-414. : http://dx.doi.org/10.1016/j.arthro.2016.07.029
  • Mehl J, Paul J, Feucht MJ, Bode G, Imhoff AB, Sudkamp NP, Hinterwimmer S: ACL deficiency and varus osteoarthritis: high tibial osteotomy alone or combined with ACL reconstruction? Arch Orthop Traum Su, 2017; 137 (2): 233-240. : http://dx.doi.org/10.1007/s00402-016-2604-8
  • Mehl J, Paul J, Feucht MJ, Bode G, Imhoff AB, Sudkamp NP, Hinterwimmer S: ACL deficiency and varus osteoarthritis: high tibial osteotomy alone or combined with ACL reconstruction? Arch Orthop Traum Su, 2017; 137 (2): 233-240. : http://dx.doi.org/10.1007/s00402-016-2604-8
  • Morath O, Kubosch EJ, Taeymans J, Zwingmann J, Konstantinidis L, Sudkamp NP, Hirschmuller A: The effect of sclerotherapy and prolotherapy on chronic painful Achilles tendinopathy-a systematic review including meta-analysis. Scand J Med Sci Spor, 2017. : http://dx.doi.org/10.1111/sms.12898
  • Navarro-Ramirez R, Lang G, Lian X, Berlin C, Janssen I, Jada A, Alimi M, Hartl R: Total navigation in spine surgery; a concise guide to eliminate fluoroscopy using a portable intraoperative-CT 3D navigation system. World Neurosurg, 2017. : http://dx.doi.org/10.1016/j.wneu.2017.01.025
  • Ogon P, Izadpanah K, Eberbach H, Lang G, Sudkamp NP, Maier D: Prognostic value of MRI in arthroscopic treatment of chronic patellar tendinopathy: a prospective cohort study. Bmc Musculoskel Dis, 2017; 18 (1): 146-146. : http://dx.doi.org/10.1186/s12891-017-1508-2
  • Rothdiener M, Uynuk-Ool T, Sudkamp N, Aurich M, Grodzinsky AJ, Kurz B, Rolauffs B: Human osteoarthritic chondrons outnumber patient- and joint-matched chondrocytes in hydrogel culture-Future application in autologous cell-based OA cartilage repair? J Tissue Eng Regen M, 2017. : http://dx.doi.org/10.1002/term.2516
  • Saier T, Minzlaff P, Feucht MJ, Lammle L, Burghoff M, Ihle C, Imhoff AB, Hinterwimmer S: Health-related quality of life after open-wedge high tibial osteotomy. Knee Surg Sport Tr A, 2017; 25 (3): 934-942. : http://dx.doi.org/10.1007/s00167-015-3938-4
  • Seidenstuecker M, Ruehe J, Suedkamp NP, Serr A, Wittmer A, Bohner M, Bernstein A, Mayr HO: Composite material consisting of microporous beta-TCP ceramic and alginate for delayed release of antibiotics. Acta Biomater, 2017; 51: 433-446. : http://dx.doi.org/10.1016/j.actbio.2017.01.045
  • Seidenstuecker Michael, Ruehe Juergen, Suedkamp Norbert, Serr Annerose, Wittmer Annette, Bohner Marc, Bernstein Anke, Mayr Hermann: Composite material consisting of microporous beta-TCP ceramic and alginate for delayed release of antibiotics ACTA BIOMATERIALIA, 2017; 51: 433-446. : http://dx.doi.org/10.1016/j.actbio.2017.01.045
  • Uynuk-Ool T, Rothdiener M, Walters B, Hegemann M, Palm J, Nguyen P, Seeger T, Stockle U, Stegemann JP, Aicher WK, Kurz B, Hart ML, Klein G, Rolauffs B: The geometrical shape of mesenchymal stromal cells measured by quantitative shape descriptors is determined by the stiffness of the biomaterial and by cyclic tensile forces. J Tissue Eng Regen M, 2017. : http://dx.doi.org/10.1002/term.2263
  • Walters B, Uynuk-Ool T, Rothdiener M, Palm J, Hart ML, Stegemann JP, Rolauffs B: Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens. Sci Rep-uk, 2017; 7 (1): 6640-6640. : http://dx.doi.org/10.1038/s41598-017-06794-9
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
  • Aurich M, Albrecht D, Angele P, Becher C, Fickert S, Fritz J, Muller PE, Niemeyer P, Pietschmann M, Spahn G, Walther M: Behandlung osteochondraler Läsionen des Sprunggelenks: Empfehlungen der Arbeitsgemeinschaft Klinische Geweberegeneration der DGOU.[Treatment of Osteochondral Lesions in the Ankle: A Guideline from the Group "Clinical Tissue Regeneration" of the German Society of Orthopaedics and Traumatology (DGOU)]. Z Orthop Unfallchir, 2017; 155 (01): 92-99. : http://dx.doi.org/10.1055/s-0042-116330

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten