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 Forschungsbericht für das Jahr 2017

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie

Abteilung II

Albertstr. 25
79104 Freiburg i. Br.
Tel: +49-761-2035313 Fax: +49-761-2035318
Email lutz.hein@pharmakol.uni-freiburg.de
http://www.pharmakologie.uni-freiburg.de/ii/welcome.htm


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Lutz Hein
  • Prof. Dr. Rolf Jackisch
  • Prof. em. Dr. Klaus Starke
  • Prof. Dr. Bela Szabo
Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Barthas F, Humo M, Gilsbach R, Waltisperger E, Karatas M, Leman S, Hein L, Belzung C, Boutillier AL, Barrot M, Yalcin I: Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression. Biol Psychiat, 2017; 82 (5): 370-379. : http://dx.doi.org/10.1016/j.biopsych.2017.01.019
  • Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M: The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovasc Res, 2017; 113 (2): 222-223. : http://dx.doi.org/10.1093/cvr/cvw248
  • Hofherr A, Busch T, Huber N, Nold A, Bohn A, Viau A, Bienaime F, Kuehn EW, Arnold SJ, Kottgen M: Efficient genome editing of differentiated renal epithelial cells. Pflug Arch Eur J Phy, 2017; 469 (2): 303-311. : http://dx.doi.org/10.1007/s00424-016-1924-4
  • Huhner L, Rilka J, Gilsbach R, Zhou X, Machado V, Spittau B: Interleukin-4 Protects Dopaminergic Neurons In vitro but Is Dispensable for Front Mol Neurosci, 2017; 10: 62-62. : http://dx.doi.org/10.3389/fnmol.2017.00062
  • Kaminski MM, Tosic J, Pichler R, Arnold SJ, Lienkamp SS: Engineering kidney cells: reprogramming and directed differentiation to renal tissues. Cell Tissue Res, 2017; 369 (1): 185-197. : http://dx.doi.org/10.1007/s00441-017-2629-5
  • Krohmer A, Brehm M, Auwarter V, Szabo B: Pregnenolone does not interfere with the effects of cannabinoids on synaptic transmission in the cerebellum and the nucleus accumbens. Pharmacol Res, 2017; 123: 51-61. : http://dx.doi.org/10.1016/j.phrs.2017.04.032
  • Lother A, Bergemann S, Kowalski J, Huck M, Gilsbach R, Bode C, Hein L: Inhibition of the cardiac myocyte mineralocorticoid receptor ameliorates doxorubicin-induced cardiotoxicity. Cardiovasc Res, 2017. : http://dx.doi.org/10.1093/cvr/cvx078 (in Druck)
  • Nothjunge S, Nuhrenberg TG, Gruning BA, Doppler SA, Preissl S, Schwaderer M, Rommel C, Krane M, Hein L, Gilsbach R: DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes. Nat Commun, 2017; 8 (1) (online): 1667-1667. : http://dx.doi.org/10.1038/s41467-017-01724-9
  • Nussbaum K, Burkhard SH, Ohs I, Mair F, Klose CSN, Arnold SJ, Diefenbach A, Tugues S, Becher B: Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. J Exp Med, 2017; 214 (8): 2331-2347. : http://dx.doi.org/10.1084/jem.20162031
  • Pfurr S, Chu YH, Bohrer C, Greulich F, Beattie R, Mammadzada K, Hils M, Arnold SJ, Taylor V, Schachtrup K, Uhlenhaut NH, Schachtrup C: The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development. Development, 2017; 144 (21): 3917-3931. : http://dx.doi.org/10.1242/dev.145698
  • Probst S, Arnold SJ: Eomesodermin-At Dawn of Cell Fate Decisions During Early Embryogenesis. Curr Top Dev Biol, 2017; 122: 93-115. : http://dx.doi.org/10.1016/bs.ctdb.2016.09.001
  • Probst S, Daza RA, Bader N, Hummel JF, Weiss M, Tanriver Y, Hevner RF, Arnold SJ: A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing. Genesis, 2017; 55 (8) (online). : http://dx.doi.org/10.1002/dvg.23043

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten