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 Forschungsbericht für das Jahr 2005

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Antes G: Was wirklich gesund macht. Die Diskussion um Vioxx und Co. zeigt: Die Qualitätssicherung in der Medizin braucht klare und funktionierende Standards. Technol Rev, 2005; 4: 38-40.
  • Antes G: Methodische Artikel in der ZaeFQ: Übersetzungen englischsprachiger Artikel? Zeitschrift für ärztliche Fortbildung und Qualität im Gesundheitswesen, 2005; 99: 628.
  • Antes G, Lang B, Diener M: Das CONSORT-Statement. PM-Report, 2005; 12: 48-49.
  • Antes G, Sauerland S, Seiler CM: Evidence-based medicine - from best research evidence to a better surgical practice and health care. Langenbeck Arch Surg, 2005; 101007: 00423-005-0006-4.
  • Augustin N, Sauerbrei W, Schumacher M: The practical utility of incorporating model selection uncertainty into prognostic models for survival data. Statistical Modelling, 2005; 5: 95-118.
  • Becker G, Soezgen T, Olschewski M, Laubenberger J, Blum HE, Allgaier H-P: Combined TACE and PEI for palliative treatment of unresectable hepatocellular carcinoma. World J Gastroentero, 2005; 11: 6104-6109.
  • Binder L, Pieske B, Olschewski M, Geibel A, Klostermann B, Reiner C, Konstantinides S: N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation, 2005; 112: 1573-1579.
  • Blümle A: 10 Jahre "Handsearching" in Deutschland - ein Beitrag zum Cochrane Central Register of Controlled Trials. Z. ärztl. Fortbild. Qual. Gesundh.wes., 2005; 99: 396-396.
  • Boettler P, Hartmann M, Watzl K, Maroula E, Schulte Mönting J, Knirsch W, Dittrich S, Kececioglu D: Heart rate effect on strain and strain rate in healthy children. J Am Soc Echocardiog, 2005; 18: 1121-1130.
  • Bohlius J, Langensiepen S, Schwarzer G, Seidenfeld J, Piper M, Bennett C, Engert A: Recombinant human erythropoietin and overall survival in cancer patients: Results of a comprehensive meta-analysis. J Natl Cancer I, 2005; 97: 489-498.
  • Bohlius JF, Langensiepen S, Engert A, Schwarzer G, Bennett CL: Effectiveness of erythropoietin in the treatment of patients with malignancies: methods and preliminary results of a Cochrane review. Best Practice & Research Clinical Haematology, 2005; 18: 449-454.
  • Burger W, Chemnitius J-M, Kneissl GD, Rücker G: Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta analysis. J Intern Med, 2005; 257: 399-414.
  • Dreier G, Marx C, Schmoor C, Maier-Lenz H: The 12th amendment to the German Drug Law. Chances and obstacles for investigator-initiated clinical trials. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2005; 48: 445-452.
  • Ehlken B, Ihorst G, Lippert B, Rohwedder A, Petersen G, Schumacher M, Forster J, and for the PRIDE Study Group: Economic impact of community-acquired and nosocomial lower respiratory tract infections in young children in Germany. Eur J Pediatr, 2005; 1: 1432-1076.
  • El-Moneim Ehab S Abd, Fuerste H-O, Krueger M, Elmagd AA, Brandis M, Schulte Mönting J, Hentschel R: Pressure support ventilation combined with volume guarantee versus synchronized intermittent mandatory ventilation: A pilot crossover trial in premature infants in their weaning phase. Pediatric Critical Care Medicine, 2005; 6: 286-292.
  • Geibel A, Zehender M, Kasper W, Olschewski M, Klima C, Konstantinides SV: Prognostic value of the ECG on admission in patients with acute major pulmonary embolism. Eur Respir J, 2005; 25: 843-848.
  • Gerds T, Türp JC, Antes G: Über die Signifikanz eines statistischen Tests und die zugehörigen Fehlentscheidungen. Deutsche Zahnärztliche Zeitschrift, 2005; 60: 181-182.
  • Gerds T, Türp JC, Antes G: Von der Trennschärfe einer statistischen Entscheidung und dem Testen auf Gleichheit. Deutsche Zahnärztliche Zeitschrift, 2005; 60: 547-548.
  • Gerds TA, Vogeler M: Endpoints and survival analysis for successful osseointegration of dental implants. Stat Methods Med Res, 2005; 14: 579-590.
  • Grundmann H, Bärwolff S, Tami A, Behnke M, Schwab F, Geffers C, Halle E, Göbel UB, Schiller R, Jonas D, Klare I, Weist K, Witte W, Beck-Beilecke K, Schumacher M, Rüden H, Gastmeier P: How many infections are caused by patient-to-patient transmission in intensive care units? Crit Care Med, 2005; 33: 946-951.
  • Handke M, Harloff A, Hetzel A, Olschewski M, Bode C, Geibel A: Predictors of left atrial spontaneous echocardiographic contrast or thrombus formation in stroke patients with sinus rhythm and reduced left ventricular function. Am J Cardiol, 2005; 96: 1342-1344.
  • Handke M, Harloff A, Hetzel A, Olschewski M, Bode C, Geibel A: Left atrial appendage flow velocity as a quantitative surrogate parameter for thromboembolic risk: determinants and relationship to spontaneous echocontrast and thrombus formation-A transesophageal echocardiographic study in 500 patients with cerebral ischemia. J Am Soc Echocardiog, 2005; 18: 1366-1372.
  • Harloff A, Handke M, Geibel A, Oehm E, Guschlbauer B, Olschewski M, Hetzel A: Do stroke patients with normal carotid arteries require TEE for exclusion of relevant aortic plaques? J Neurol Neurosur Ps, 2005; 76: 1654-1658.
  • Jocher A, Kessler S, Hornstein S, Schulte Mönting J, Schempp CM: The UV erythema test as a model to investigate the anti-inflammatory potency of topical preparations-reevaluation and optimization of the method. Skin Pharmacol Phys, 2005; 18: 234-240.
  • Jungraithmayr W, Burger D, Olschewski M, Eggstein S: Cryoablation of malignant liver tumors: results of a single center study. Hepatobiliary Pancreat Dis Int, 2005; 4: 554-560.
  • Jungraithmayr W, Hasse J, Olschewski M, Stoelben E: Sekundäre Pneumonektomien. Indikation und Langzeitergebnisse. Chirurg, 2005; 76: 157-166.
  • Kaufmann M, Graf E, Jonat W, Eiermann W, Geberth M, Albert U-S, Gademann G, Conrad B, Stahl K, Minckwitz von G, Schumacher M: Tamoxifen versus control after adjuvant, risk-adapted chemotherapy in postmenopausal, receptor-negative patients with breast cancer: A randomized trial (GABG-IV D-93) - The German Adjuvant Breast Cancer Group. J Clin Oncol, 2005; 23: 7842-7848.
  • Kielbassa AM, Gillmann L, Zantner C, Meyer-Lueckel H, Hellwig E, Schulte Mönting J: Profilometric and microradiographic studies on the effects of toothpaste and acidic gel abrasivity on sound and demineralized bovine dental enamel. Caries Res, 2005; 39: 380-386.
  • Kielbassa AM, Oeschger U, Schulte Mönting J, Meyer-Lueckel H: Microradiographic study on the effects of salivary proteins on in vitro demineralization of bovine enamel. J Oral Rehabil, 2005; 32: 90-96.
  • Kopp MV, Semmler S, Ihorst G, Berner R, Forster J: Hospital admission with neonatal sepsis and development of atopic disease: Is there a link? Pediatr Allergy Immu, 2005; 16: 630-636.
  • Korinthenberg R, Schessl J, Kirschner J, Schulte Mönting J: Intravenously administered immunoglobulin in the treatment of childhood Guillain-Barre syndrome: a randomized trial. Pediatrics, 2005; 116: 8-14.
  • Kristeva R, Chakarov V, Losch F, Hummel S, Popa T, Schulte Mönting J: Electroencephalographic spectral power in writer's cramp patients: Evidence for motor cortex malfunctioning during the cramp. Neuroimage, 2005; 27: 706-714.
  • Lang B, Sänger S: Evidenzbasierte Medizin für den Bürger. Bundesgesundheitsbl - Gesundheitsforsch - Gesundheitsschutz, 2005; 6: 679-684.
  • Lang B, Sänger S, Zerbst M: Der Weg durch den "Informationsdschungel". Esslinger Gesundheitsmagazin, 2005; 1: 44-44.
  • Lelgemann M, Lang B, Kunz R, Antes G: Leitlinien. Was haben Ärzte und Patienten davon. Bundesgesundheitsbl - Gesundheitsforsch - Gesundheitsschutz, 2005; 48: 215-220.
  • Limberger N, Roßner R, Sauermann W, Feuerstein TH: Agonist concentration-response models in mouse and rabbit neocortex: Re-evaluation of classical models in comparison with a recently developed general response function. Int J Pharm, 2005; 1: 55-70.
  • Ludwig C, Stoelben E, Olschewski M, Hasse J: Comparison of morbidity, 30-day mortality, and long-term survival after pneumonectomy and sleeve lobectomy for non-small cell lung carcinoma. Ann Thorac Surg, 2005; 79: 968-973.
  • Maier PC, Funk J, Schwarzer G, Antes G, Falck-Ytter Y: Treatment of ocular hypertension and open angle glaucoma: meta-analysis of randomised controlled trials. Brit Med J, 2005; 331: 134-134.
  • McShane LM, Altman DG, Sauerbrei W: Identification of clinically useful cancer prognostic factors: What are we missing? J Natl Cancer I, 2005; 97: 1023-1025.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM, for the Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: Reporting recommendations for tumor marker prognostic studies (REMARK). J Natl Cancer I, 2005; 97: 1180-1184.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM: Reporting recommendations for tumor MARKer prognostic studies (REMARK). Nat Clin Pract Oncol, 2005; 2: 416-422.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM, Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: REporting recommendations for tumor MARKer prognostic studies (REMARK). Brit J Cancer, 2005; 22: 387-391.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM, for the Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: REporting recommendations for tumor MARKer prognostic studies (REMARK). Eur J Cancer, 2005; 41: 1690-1696.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM, for the Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: Reporting recommendations for tumor marker prognostic studies. J Clin Oncol, 2005; 23: 9067-9072.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM: REporting recommendations for tumor MARKer prognostic studies (REMARK);Statistics Subcommittee of the NCI-EORTC working Group on Cancer Diagnostics Nat Clin Pract Urol(Nature Clinical Practise Urology), 2005; 2: 416-422.
  • Mergner T, Schweigart G, Maurer C, Blümle A: Human postural responses to motion of real and virtual visual environment under different support base conditions. Exp Brain Res, 2005; 167 (4): 535-556.
  • Minckwitz von G, Raab G, Caputo A, Schütte M, Hilfrich J, Blohmer JU, Gerber B, Costa SD, Merkle E, Eidtmann H, Lampe D, Jackisch C, Bois du A, Kaufmann M: Doxorubicin with Cyclophosphamide followed by Docetaxel every 21 days compared with Doxorubicin and Docetaxel 14 days as preoperative treatment in operable breast cancer: The GEPARDUO Study of the German Breast Group. J Clin Oncol, 2005; 23: 2676-2685.
  • Mockenhaupt M, Messenheimer J, Tennis P, Schlingmann J: Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. Neurology, 2005; 64: 1134-1138.
  • Momm F, Volegova-Neher NJ, Schulte Mönting J, Guttenberger R: Different saliva substitutes for treatment of Xerostomia following radiotherapy. A prospective crossover study. Strahlenther Onkol, 2005; 181: 231-236.
  • Motschall E, Falck-Ytter Y: Searching the MEDLINE literature database through PubMed: A short guide. Onkologie, 2005; 28: 517-522. : http://dx.doi.org/10.1159/000087186
  • Motschall E, Timmer A, Türp JC, Antes G: Die TRIP-Datenbank: Ein wenig bekanntes Informationsportal für die evidenzbasierte Medizin. Deutsche Zahnärztliche Zeitschrift, 2005; 60: 658-660. (download: http://www.zahnheilkunde.de/beitragpdf/pdf_3435.pdf)
  • Motschall E, Türp JC, Antes G: PubMed - Erweiterung beim Automatic Term Mapping. Deutsche Zahnärztliche Zeitschrift, 2005; 60: 67-68. (download: http://www.zahnheilkunde.de/beitragpdf/pdf_2506.pdf)
  • Motschall E, Türp JC, Antes G: Datenübergreifende Literatursuche mit MedPilot (Teil 1). Deutsche Zahnärztliche Zeitschrift, 2005; 60: 307-308. (download: http://www.zahnheilkunde.de/beitragpdf/pdf_2913.pdf)
  • Motschall E, Türp JC, Antes G: Datenübergreifende Literatursuche mit MedPilot (Teil 2). Deutsche Zahnärztliche Zeitschrift, 2005; 60: 427-429. (download: http://www.zahnheilkunde.de/beitragpdf/pdf_3105.pdf)
  • Müller AMS, Ihorst G, Mertelsmann R, Engelhardt M: Epidemiology of non-Hodgkin's lymphoma (NHL): trends, geographic distribution, and etiology. Ann Hematol, 2005; 84: 1-12.
  • Nagata T, Schmelzeisen R, Mattern D, Schwarzer G, Ohishi M: Application of fuzzy inference to European patients to predict cervical lymph nodes metastasis in carcinoma of the tongue. Int J Oral Max Surg, 2005; 34: 138-142.
  • Rossner R: Zum Wandel der Informationstechnologie in der Medizinischen Biometrie und Statistik. GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005; 1 (2): DOC-10.
  • Royston P, Sauerbrei W: Building multivariable regression models with continuous covariates in clinical epidemiology. Method Inform Med, 2005; 4: 561-571.
  • Schindler TH, Nitzsche EU, Schelbert HR, Olschewski M, Sayre J, Mix M, Brink I, Zhang X-L, Kreissl M, Magosaki N, Just H, Solzbach U: Positron emission tomography-measured abnormal responses of myocardial blood flow to sympathetic stimulation are associated with the risk of developing cardiovascular events. J Am Coll Cardiol, 2005; 45: 1505-1512.
  • Schmitt-Graeff A, Ertelt-Heitzmann V, Allgaier H-P, Olschewski M, Nitschke R, Haxelmans S, Koelble K, Behrens J, Blum HE: Coordinated expression of cyclin D1 and LEF-1/TCF transcription factor is restricted to a subset of hepatocellular carcinoma. Liver Int, 2005; 25: 839-847.
  • Schreyer AG, Gölder S, Scheibl K, Volk M, Lenhart M, Timmer A, Scholmerich J, Feuerbach S, Rogler G, Herfarth H, Seitz J: Dark lumen magnetic resonance enteroclysis in combination with MRI colonography for whole bowel assessment in patients with Crohn's disease: first clinical experience. Inflamm Bowel Dis, 2005; 11: 388-394.
  • Schulgen G, Olschewski M, Krane V, Wanner C, Ruf G, Schumacher M: Sample sizes for clinical trials with time-to-event endpoints and competing risks. Contemp Clin Trials, 2005; 26: 386-395.
  • Schumacher M: Wie die Medizinische Statistik nach Freiburg kam. - Eine historische Perspektive. GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005; 1 (2): DOC-07.
  • Spyridonidis A, Bertz H, Ihorst G, Grüllich C, Finke J: Hematopoietic cell transplantation from unrelated donors as an effective therapy for older patients (>_ 60 years) with active myeloid malignancies. Blood, 2005; 105: 4147-4148.
  • Stappert CF, Ozden U, Gerds T, Strub JR: Longevity and failure load of ceramic veneers with different preparation designs after exposure to masticatory simulation. J Prosthet Dent, 2005; 94: 132-139.
  • Stappert CF, Stathopoulou N, Gerds T, Strub JR: Survival rate and fracture strength of maxillary incisors, restored with different kinds of full veneers. J Oral Rehabil, 2005; 32: 266-272.
  • Stiglmayr CE, Grathwol T, Linehan MM, Ihorst G, Fahrenberg J, Bohus M: Aversive tension in patients with borderline personality disorder: a computer-based controlled field study. Acta Psychiat Scand, 2005; 111: 372-379.
  • Taschner CA, Kirsch EC, Scheffler K, Wetzel SG, Schulte Mönting J, Kappos L, Radu EW: Optimizing brain MRI protocols in the follow-up of patients with multiple sclerosis T2-weighted MRI of the brain after the administration of gadopentetate dimeglumine. Magn Reson Imaging, 2005; 23: 469-474.
  • Timmer A: Book reviews: Medical Statistics from A to Z. By Everitt BS. Biometrics, 2005; 61: 640-641.
  • Türp JC, Alpaslan C, Gerds T: Is there a greater mandibular movement capacity towards the left? Verification of an observation from 1921. J Oral Rehabil, 2005; 32: 242-247.
  • Türp JC, Röhrich C, Antes G: Evidence-based dentistry in German language dental journals 1997 - 2003. Evidence-Based Dentistry, 2005; 6: 86-87.
  • van der Hoek L, Sure K, Ihorst G, Stang A, Pyrc K, Jebbink MF, Petersen G, Forster J, Berkhout B, Uberla K: Croup is associated with the novel coronavirus NL63. PLoS Medicine, 2005; 2: 764-770.
  • Wanner C, Krane V, März W, Olschewski M, Mann JFE, Ruf G, Ritz E, for the German Diabetes, Dialysis Study Investigators: Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. New Engl J Med, 2005; 353: 238-248.
  • Weingart O, Skoetz N, Lang B, Richter B, Engert A: Patientenbeteiligung in der Cochrane Collaboration. Barrieren, Erfahrungen und Konzepte aus deutscher Sicht. Z Aerztl Fortbild Qual Gesundh wes, 2005; 99: 367-371.
  • Zankel E, Rogler G, Andus T, Reng CM, Scholmerich J, Timmer A: Crohn's disease patient characteristics in a tertiary referral center: comparison with patients from a population-based cohort. Eur J Gastroen Hepat, 2005; 17: 395-401.
  • Zeiser R, Spyridonidis A, Wäsch R, Ihorst G, Grüllich C, Bertz H, Finke J: Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative allogeneic hematopoietic cell transplantation. Leukemia, 2005; 19: 814-821.
Rezensionen:
  • Beyersmann J: Book Reviews. Editor: Petra Macaskill Stat Med, 2005; 24: 2581-2582.
Buchbeiträge:
  • Galandi D, Antes G, Bassler D: Evidenzbasierte Medizin. In: Prof. Dr. Jürgen Schölmerich (Hrsg.): Medizinische Therapie 200/2006., 2. Auflage. Heidelberg: Springer-Verlag, 2005; 9-13.: http://dnb.ddb.de
  • Graf E: Explained variation measures in survival analysis. In: Peter Armitage, Theodore Colton (Hrsg.): Encyclopedia of Biostatistics, 3. Auflage. chichester: John Wiley & Sons, Ltd, 2005; 1856-1858.
  • Sauerbrei W: Prognostic Factors. Confusion caused by bad quality of design, analysis and reporting of many studies. In: Bier H (Hrsg.): Current Research in Head and Neck Cancer. Basel: Karger, 2005; 184-200.
Fallbeispiele:
  • Merger M, Andus T, Schlottmann K, Timmer A, Scholmerich J, Messmann H, Marienhagen J, Rummle P, Krolak C: A rare case of hypalbuminaemic oedema. Gut, 2005; 54: 320-335.
Kurzbeiträge / short communications:
  • Antes G: Leserzuschrift: Kommentar zu einem Leserbrief über Studienregister im Deutschen Ärzteblatt. Z. ärztl. Fortbild. Qual. Gesundh.wes., 2005; 99: 663.
  • Antes G, Dreier G, Encke A, Ohmann C, Seiler C, Victor N: Plädoyer für die Einrichtung eines öffentlichen Registers. Deutsches Ärzteblatt, 2005; 27: A1937-A1937.
  • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM: Re: Reporting recommendations for tumor marker prognostic studies (REMARK), Response of Authors. J Natl Cancer I, 2005; 97: 1855-1856.
  • Sauerbrei W, Royston P, Schumacher M: Austin, P.C., and Tu, J.V. (2004), "Bootstrap Methods for developing predictive models", The American Statistician,58, 131-137: Comment by Sauerbrei, Royston, and Schumacher to reply. Am Stat, 2005; 59: 116-118.