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 Forschungsbericht für das Jahr 2017

Klinik für Neurochirurgie

Breisacher Str. 64
79106 Freiburg
Tel: +49 761 270 50010 Fax: +49 761 270 50240
Email neurochirurgie@uniklinik-freiburg.de
https://www.uniklinik-freiburg.de/neurochirurgie.html


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Epilepsie
  • Neuroonkologie
  • Neuropharmakologie
  • Tumorangiogenese
  • Vaskuläre Neurochirurgie
  • Brain Tumor Stem Cell Research
  • Neuroelektronische Schnittstellen

Wissenschaftliche Projekte und Forschungsvorhaben


  • Die wissenschaftlichen Projekte und Forschungsvorhaben werden auf der Homepage der Klinik für Neurochirurgie unter der Rubrik "Forschung" beschrieben.

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Al-Moujahed A, Brodowska K, Stryjewski TP, Efstathiou NE, Vasilikos I, Cichy J, Miller JW, Gragoudas E, Vavvas DG: Verteporfin inhibits growth of human glioma in vitro without light activation. Sci Rep-uk, 2017; 7 (1) (online): 7602. : http://dx.doi.org/10.1038/s41598-017-07632-8
  • Blumcke I, Spreafico R, Haaker G, Coras R, Kobow K, Bien CG, Pfafflin M, Elger C, Widman G, Schramm J, Becker A, Braun KP, Leijten F, Baayen JC, Aronica E, Chassoux F, Hamer H, Stefan H, Rossler K, Thom M, Walker MC, Sisodiya SM, Duncan JS, McEvoy AW, Pieper T, Holthausen H, Kudernatsch M, Meencke HJ, Kahane P, Schulze-Bonhage A, Zentner J, Heiland DH, Urbach H, Steinhoff BJ, Bast T, Tassi L, Lo Russo G, Ozkara C, Oz B, Krsek P, Vogelgesang S, Runge U, Lerche H, Weber Y, Honavar M, Pimentel J, Arzimanoglou A, Ulate-Campos A, Noachtar S, Hartl E, Schijns O, Guerrini R, Barba C, Jacques TS, Cross JH, Feucht M, Muhlebner A, Grunwald T, Trinka E, Winkler PA, Gil-Nagel A, Toledano Delgado R, Mayer T, Lutz M, Zountsas B, Garganis K, Rosenow F, Hermsen A, von Oertzen TJ, Diepgen TL, Avanzini G: Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery. New Engl J Med, 2017; 377 (17): 1648-1656. : http://dx.doi.org/10.1056/NEJMoa1703784
  • Cosandier-Rimélé D, Ramantani G, Zentner J, Schulze-Bonhage A, Duempelmann M: A realistic multimodal modeling approach for the evaluation of distributed source analysis: application to sLORETA. J Neural Eng, 2017; 14 (5) (online): 056008. : http://dx.doi.org/10.1088/1741-2552/aa7db1
  • Dagmar D, Proescholdt M, Reinert C, Pietsch T, Jones DTW, Pfister SM, Hattingen E, Seidel C, Dirven L, Luerding R, Reijneveld J, Warmuth-Metz M, Bonsanto M, Bremer M, Combs S, Rieken S, Herrlinger U, Kuntze H, Mayer-Steinacker R, Moskopp D, Schneider T, Beringer A, Schlegel U, Stummer W, Welker H, Weyerbrock A, Paulsen F, Rutkowski S, Weller M, Wick W, Kortmann RD, Bogdahn U, Hau P: Multicenter pilot study of radio-chemotherapy as first-line treatment for adults with medulloblastoma (NOA-07). Neuro-oncology, 2017. : http://dx.doi.org/10.1093/neuonc/nox155 (in Druck)
  • Delev D, Schramm J, Clusmann H: How I do it - selective amygdalohippocampectomy via a navigated temporobasal approach, when veins forbid elevation of the temporal lobe. Acta Neurochir, 2017. : http://dx.doi.org/10.1007/s00701-017-3386-7 (in Druck)
  • Demerath T, Simon-Gabriel CP, Kellner E, Schwarzwald R, Lange T, Heiland DH, Reinacher P, Staszewski O, Mast H, Kiselev VG, Egger K, Urbach H, Weyerbrock A, Mader I: Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype? J Neuroradiology, 2017; 30 (1): 36-47. : http://dx.doi.org/10.1177/1971400916678225
  • Donkels C, Pfeifer D, Janz P, Huber S, Nakagawa J, Prinz M, Schulze-Bonhage A, Weyerbrock A, Zentner J, Haas CA: Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Cereb Cortex, 2017; 27 (2): 1558-1572. : http://dx.doi.org/10.1093/cercor/bhv346
  • Fedele V, Dai F, Masilamani A, Heiland DH, Kling E, Gätjens-Sanchez A, Ferrarese R, Platania L, Doostkam S, Kim H, Nelander S, Weyerbrock A, Prinz M, Califano A, Iavarone A, Bredel M, Carro MS: Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression. Mol Cancer Res, 2017; 15 (8): 998-1011. : http://dx.doi.org/10.1158/1541-7786.MCR-16-0494
  • Foit N: Hippocampal atrophy after temporal lobe lesionectomy with surgical sparing of the hippocampus. J Neurosurg, 2017. (in Druck)
  • Gkogkidis CA, Wang X, Schubert T, Gierthmühlen M, Kohler F, Schulze-Bonhage A, Burgard W, Rickert J, Haberstroh J, Schüttler M, Stieglitz T, Ball T: Closed-loop interaction with the cerebral cortex using a novel micro-ECoG-based implant: the impact of beta vs. gamma stimulation frequencies on cortico-cortical spectral responses. Brain-Computer Interfaces, 2017; 4 (4) (online): 214-224. : https://doi.org/10.1080/2326263X.2017.1381829
  • Grauvogel J, Scheiwe C, Masalha W, Jarc N, Grauvogel T, Beringer A: Piezosurgery in modified pterional orbital decompression surgery in Graves' disease. World Neurosurg, 2017; 106 (10): 422-429. : http://dx.doi.org/10.1016/j.wneu.2017.06.180
  • Grauvogel TD, Engelskirchen P, Semper-Hogg W, Grauvogel J, Laszig R: Navigation accuracy after automatic- and hybrid-surface registration in sinus and skull base surgery. Plos One, 2017; 12 (7) (online): e0180975. : http://dx.doi.org/10.1371/journal.pone.0180975
  • Guenzle J, Wolf LJ, Garrelfs N, Goeldner JM, Osterberg N, Schindler CR, Saavedra JE, Weyerbrock A: ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFkappaB and STAT3 inhibition in glioblastoma Cell Death Discovery, 2017; 3 (online): 17006. : http://dx.doi.org/10.1038/cddiscovery.2017.6
  • Hattingen E, Enkirch SJ, Jurcoane A, Kruse M, Delev D, Grote A, Becker A: Hippocampal "gliosis only" on MR imaging represents a distinct entity in epilepsy patients. Neuroradiology, 2017. : http://dx.doi.org/10.1007/s00234-017-1939-3 (in Druck)
  • Heckler M, Osterberg N, Guenzle J, Thiede-Stan NK, Reichardt W, Weidensteiner C, Saavedra JE, Weyerbrock A: The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation. Tumor Biol, 2017; 39 (6) (online). : http://dx.doi.org/10.1177/1010428317703922
  • Heiland DH, Demerath T, Kellner E, Kiselev VG, Pfeifer D, Schnell O, Staszewski O, Urbach H, Weyerbrock A, Mader I: Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme. Oncotarget, 2017; 8 (7): 11083-11093. : http://dx.doi.org/10.18632/oncotarget.11522
  • Heiland DH, Ferrarese R, Claus R, Dai F, Masilamani AP, Kling E, Weyerbrock A, Kling T, Nelander S, Carro MS: c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas. Oncotarget, 2017; 8 (4): 6940-6954. : http://dx.doi.org/10.18632/oncotarget.14330
  • Heiland DH, Haaker G, Delev D, Mercas B, Masalha W, Heynckes S, Gäbelein A, Pfeifer D, Carro MS, Weyerbrock A, Prinz M, Schnell O: Comprehensive analysis of PD-L1 expression in glioblastoma multiforme Oncotarget, 2017; 8: 42214-42225. : http://dx.doi.org/10.18632/oncotarget.15031
  • Heiland DH, Simon-Gabriel CP, Demerath T, Haaker G, Pfeifer D, Kellner E, Kiselev VG, Staszewski O, Urbach H, Weyerbrock A, Mader I: Integrative Diffusion-Weighted Imaging and Radiogenomic Network Analysis of Glioblastoma multiforme. Sci Rep-uk, 2017; 7 (online): 43523. : http://dx.doi.org/10.1038/srep43523
  • Heiland DH, Wörner J, Gerrit Haaker J, Delev D, Pompe N, Mercas B, Franco P, Gäbelein A, Heynckes S, Pfeifer D, Weber S, Mader I, Schnell O: The integrative metabolomic-transcriptomic landscape of glioblastome multiforme. Oncotarget, 2017; 8 (30): 49178-49190. : http://dx.doi.org/10.18632/oncotarget.16544
  • Heynckes S, Gaebelein A, Haaker G, Grauvogel J, Franco P, Mader I, Carro MS, Prinz M, Delev D, Schnell O, Heiland DH: Expression differences of programmed death ligand 1 in de-novo and recurrent glioblastoma multiforme. Oncotarget, 2017; 8 (27) (online): 18819. : http://dx.doi.org/10.18632/oncotarget.18819
  • Jabbarli R, Reinhard M, Roelz R, Kaier K, Weyerbrock A, Taschner C, Scheiwe C, Shah M: Clinical relevance of anterior cerebral artery asymmetry in aneurysmal subarachnoid hemorrhage. J Neurosurg, 2017; 127 (5): 1070-1076. : http://dx.doi.org/10.3171/2016.9.JNS161706
  • Klingler JH, Sircar R, Scheiwe C, Kogias E, Krüger MT, Scholz C, Hubbe U: Comparative Study of C-Arms for Intraoperative 3-Dimensional Imaging and Navigation in Minimally Invasive Spine Surgery Part II - Radiation Exposure. Clin Spine Surg, 2017; 30 (6): E669-E676. : http://dx.doi.org/10.1097/BSD.0000000000000187
  • Klingler JH, Sircar R, Scheiwe C, Kogias E, Volz F, Krüger MT, Hubbe U: Comparative Study of C-Arms for Intraoperative 3-Dimensional Imaging and Navigation in Minimally Invasive Spine Surgery Part I - Applicability and Image Quality. Clin Spine Surg, 2017; 30 (6): 276-284. : http://dx.doi.org/10.1097/BSD.0000000000000186
  • Kogias E, Altenmüller DM, Klingler JH, Schmeiser B, Urbach H, Doostkam S: Histopathology of 3 Tesla MRI-negative temporal lobe epilepsies. J Clin Neurosci, 2017. : http://dx.doi.org/10.1016/j.jocn.2017.10.012 (in Druck)
  • Kogias E, Klingler JH, Franco Jimenez P, Vasilikos I, Sircar R, Scholz C, Hubbe U: Incidental Durotomy in Open Versus Tubular Revision Microdiscectomy: A Retrospective Controlled Study on Incidence, Management, and Outcome. Clin Spine Surg, 2017; 30 (10): E1333-E1337. : http://dx.doi.org/10.1097/BSD.0000000000000279
  • Kogias E, Klingler JH, Urbach H, Scheiwe C, Schmeiser B, Doostkam S, Zentner J, Altenmüller DM: 3 Tesla MRI-negative focal epilepsies: Presurgical evaluation, postoperative outcome and predictive factors. Clin Neurol Neurosur, 2017; 163: 116-120. : http://dx.doi.org/10.1016/j.clineuro.2017.10.038
  • Kohler F, Gkogkidis A, Bentler C, Wang X, Gierthmühlen M, Fischer J, Stolle C, Reindl L, Rickert J, Stieglitz T, Ball T, Schüttler M: Closed-loop interaction with the cerebral cortex: present and future of wireless implant technology. Brain-Computer Interfaces, 2017; 4 (3): 146-154. : http://dx.doi.org/10.1080/2326263X.2017.1338011
  • Masalha W, Heiland DH, Franco P, Delev D, Haaker JG, Schnell O, Scheiwe C, Grauvogel J: Atypical meningioma: progression-free survival in 161 cases treated at our institution with surgery versus surgery and radiotherapy. J Neuro-oncol, 2017. : http://dx.doi.org/10.1007/s11060-017-2634-2 (in Druck)
  • Masilamani AP, Ferrarese R, Kling E, Thudi NK, Kim H, Scholtens DM, Dai F, Hadler M, Unterkircher T, Platania L, Weyerbrock A, Prinz M, Gillespie GY, Harsh IV GR, Bredel M, Carro MS: KLF6 depletion promotes NF-kappaB signaling in glioblastoma. Oncogene, 2017; 36 (25): 3562-3575. : http://dx.doi.org/10.1038/onc.2016.507
  • Nakagawa JM, Donkels C, Fauser S, Schulze-Bonhage A, Prinz M, Zentner J, Haas CA: Characterization of focal cortical dysplasia with balloon cells by layer-specific markers: Evidence for differential vulnerability of interneurons. Epilepsia, 2017; 58 (4): 635-645. : http://dx.doi.org/10.1111/epi.13690
  • Oldrini B, Hsieh W-Y, Erdjument-Bromage H, Codega P, Carro MS, Curiel-García A, Campos C, Pourmaleki M, Grommes C, Vivanco I, Rohle D, Beilski C, Taylor B, Hollmann T, Rosenblum M, Tempst P, Blenis J, Squatrito M, Mellinghoff IK: EGFR feedback-inhibition by Ran-Binding Protein 6 is disrupted in cancer. Nat Commun, 2017; 8 (online): 2035. : https://www.nature.com/articles/s41467-017-02185-w
  • Peto I, Scheiwe C, Kogias E, Hubbe U: Minimally Invasive Posterior Cervical Foraminotomy: Freiburg Experience With 34 Patients. Clin Spine Surg, 2017; 30 (10): E1419-E1425. : http://dx.doi.org/10.1097/BSD.0000000000000517
  • Ramantani G, Kadish NE, Mayer H, Anastasopoulos C, Wagner K, Reuner G, Strobl K, Schubert-Bast S, Wiegand G, Brandt A, Korinthenberg R, Mader I, van Velthoven V, Zentner J, Schulze-Bonhage A, Bast T: Frontal Lobe Epilepsy Surgery in Childhood and Adolescence: Predictors of Long-Term Seizure Freedom, Overall Cognitive and Adaptive Functioning. Neurosurgery, 2017. : http://dx.doi.org/10.1093/neuros/nyx340 (in Druck)
  • Ramantani G, Stathi A, Brandt A, Strobl K, Schubert-Bast S, Wiegand G, Korinthenberg R, van Velthoven V, Zentner J, Schulze-Bonhage A, Bast T: Posterior cortex epilepsy surgery in childhood and adolescence: predictors of long-term seizure outcome. Epilepsia, 2017; 58 (3): 412-419. : http://dx.doi.org/10.1111/epi.13654
  • Reinacher PC, Coenen VA, Kraeutle R, Scheiwe C, Jabbarli R, Roelz R: Feasibility of stereotactic catheter ventriculocisternostomy for cisternal lavage therapy in patients with subarachnoid hemorrhage. Clin Neurol Neurosur, 2017; 163: 94-102. : http://dx.doi.org/10.100710.1016/j.clineuro.2017.10.012
  • Reinacher PC, Krüger MT, Coenen VA, Shah M, Roelz R, Jenkner C, Egger K: Determining the Orientation of Directional Deep Brain Stimulation Electrodes Using 3D Rotational Fluoroscopy. Am J Neuroradiol, 2017; 38 (6): 1111-1116. : http://dx.doi.org/10.3174/ajnr.A5153
  • Roelz R, Coenen VA, Scheiwe C, Niesen WD, Egger K, Csok I, Kraeutle R, Jabbarli R, Urbach H, Reinacher PC: Stereotactic Catheter Ventriculocisternostomy for Clearance of Subarachnoid Hemorrhage: A Matched Cohort Study. Stroke, 2017; 48 (10): 2704-2709. : http://dx.doi.org/10.1161/STROKEAHA.117.018397
  • Roelz R, Scheiwe C, Urbach H, Coenen VA, Reinacher P: Stereotactic Catheter Ventriculocisternostomy for Clearance of Subarachnoid Hemorrhage in Patients with Coiled Aneurysms. Oper Neurosurg (Hagerstown), 2017. : http://dx.doi.org/10.1093/ons/opx129 (in Druck)
  • Schäfer N, Proescholdt M, Steinbach JP, Weyerbrock A, Hau P, Grauer O, Goldbrunner R, Friedrich F, Rohde V, Ringel F, Schlegel U, Sabel M, Ronellenfitsch MW, Uhl M, Grau S, Hänel M, Schnell O, Krex D, Vajkoczy P, Tabatabai G, Mack F, Schaub C, Tzaridis T, Nießen M, Kebir S, Leutgeb B, Urbach H, Belka C, Stummer W, Glas M, Herrlinger U: Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma. Neuro-oncology, 2017. : http://dx.doi.org/10.1093/neuonc/nox204 (in Druck)
  • Schmeiser B, Daniel M, Kogias E, Böhringer D, Egger K, Yang S, Foit NA, Schulze-Bonhage A, Steinhoff BJ, Zentner J, Lagrèze WA, Gross NJ: Visual field defects following different resective procedures for mesiotemporal lobe epilepsy. Epilepsy Behav, 2017; 76: 39-45. : http://dx.doi.org/10.1016/j.yebeh.2017.08.037
  • Schmeiser B, Li J, Brandt A, Zentner J, Doostkam S, Freiman TM: Different mossy fiber sprouting patterns in ILAE hippocampal sclerosis types. Epilepsy Res, 2017; 136: 115-122. : http://dx.doi.org/10.1016/j.eplepsyres.2017.08.002
  • Schmeiser B, Wagner K, Schulze-Bonhage A, Elger CE, Steinhoff BJ, Wendling AS, Mader I, Prinz M, Scheiwe C, Zentner J: Transsylvian Selective Amygdalohippocampectomy for Mesiotemporal Epilepsy: Experience with 162 Procedures. Neurosurgery, 2017; 80 (3): 454-464. : http://dx.doi.org/10.1093/neuros/nyw089
  • Schmeiser B, Wagner K, Schulze-Bonhage A, Mader I, Wendling AS, Steinhoff BJ, Prinz M, Scheiwe C, Weyerbrock A, Zentner J: Surgical Treatment of Mesiotemporal Lobe Epilepsy: Which Approach is Favorable? Neurosurgery, 2017; 81 (6): 992-1004. : http://dx.doi.org/10.1093/neuros/nyx138
  • Schmeiser B, Zentner J, Prinz M, Brandt A, Freiman TM: Extent of mossy fiber sprouting in patients with mesiotemporal lobe epilepsy correlates with neuronal cell loss and granule cell dispersion. Epilepsy Res, 2017; 129: 51-58. : http://dx.doi.org/10.1016/j.eplepsyres.2016.11.011
  • Schmeiser B, Zentner J, Steinhoff BJ, Brandt A, Schulze-Bonhage A, Kogias E, Hammen T: The role of presurgical EEG parameters and of reoperation for seizure outcome in temporal lobe epilepsy. Seizure-eur J Epilep, 2017; 51: 174-179. : http://dx.doi.org/10.1016/j.seizure.2017.08.015
  • Schmeiser B, Zentner J, Steinhoff BJ, Schulze-Bonhage A, Kogias E, Wendling AS, Hammen T: Functional hemispherectomy is safe and effective in adult patients with epilepsy. Epilepsy Behav, 2017; 77: 19-25. : http://dx.doi.org/10.1016/j.yebeh.2017.09.021
  • Scholz C, Hubbe U, Kogias E, Roelz R, Klingler JH: Microsurgical resection of juxtafacet cysts without concomitant fusion-Long-term follow-up of 74 patients. Clin Neurol Neurosur, 2017; 153 (2): 35-40. : http://dx.doi.org/10.1016/j.clineuro.2016.12.008
  • Urbach H, Egger K, Rutkowski K, Nakagawa JM, Schmeiser B, Reisert M, Brandt A, Steinhoff BJ, Schulze-Bonhage A, Hammen T: Bilateral cingulum fiber reductions in temporal lobe epilepsy with unilateral hippocampal sclerosis. Eur J Radiol, 2017; 94: 53-57. : http://dx.doi.org/10.1016/j.ejrad.2017.07.015
  • Wang X, Gkogkidis A, Iljina O, Fiederer L, Henle C, Mader I, Kaminsky J, Stieglitz T, Gierthmuehlen M, Ball T: Mapping the fine structure of cortical activity with different micro-ECoG electrode array geometries. J Neural Eng, 2017; 14 (5) (online): 056004. : http://dx.doi.org/10.1088/1741-2552/aa785e
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
Buchbeiträge:
  • Zentner J, Ramantani G: Epilepsiechirurgie bei Kindern: Operationsindikationen und - methoden. In: Bächli H, Lütschg J, Messing-Jünger M (Hrsg.): Pädiatrische Neurochirurgie Heidelberg, Germany: Springer Verlag, 2017.
Fallbeispiele:
  • Taschner CA, Sankowski R, Hubbe U, Urbach H, Schacht H, Prinz M: Freiburg Neuropathology Case Conference: Intradural, Intramedullary Mass Lesion in a 66-year-old Patient. Clin Neuroradiol, 2017; 27 (4): 525-529. : http://dx.doi.org/10.1007/s00062-017-0642-4
Vorträge:
  • Fedele V, Dai F, Masilamani AP, Carro MS: Poster: ZBTB18 Methylation Promotes Mesenchymal Transformation in Glioblastoma. 2017 (Primary and secondary brain tumors. Madrid, Spain 19-22 February 2017).
  • Franco P: Integrative analysis of surgical, neurological and oncological outcomes of corpus callosum glioblastoma multiforme. 2017 (DGNC-Jahrestagung 15.05.2017 in Magdeburg).
  • Gierthmuehlen M, Aguirre D, Koenne N, Plachta D: Neuromodulation against resistant hypertension: Efficiency of ECG-synchronized selective vagal nerve stimulation in an acute sheep model. 2017 (Jahrestagung DGNC 2017, Magdeburg).
  • Gierthmühlen M: Device-mediated-therapy – a neurosurgeon"s perspective on implant design and device location. 2017 (DGBMT Jahrestagung 2017, Dresden).
  • Hohenhaus M, Brühl M, Heiland DH, Shah M: Optimal valve selection in treatment of adult hydrocephalus - Selection depended on the origin etiology? 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie 2017, Magdeburg).
  • Hohenhaus M, Brühl M, Heiland DH, Shah M: The etiology of hydrocephalus is a risk factor for shunt infection. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie 2017, Magdeburg).
  • Nakamura L, Göbel U, Paul D, Shah M, Zentner J, Schulze-Bonhage A, Jacobs J: Poster: Intra- und postoperative Blutungen nach epilepsiechirurgischen Eingriffen im Kindesalter sind eher durch den Umfang der Operation als durch die präoperative Gerinnungssituation beeinflusst. 2017 (10. Gemeinsamen Jahrestagung der Deutschen und Österreichischen Gesellschaften für Epileptologie und der Schweizerischen Epilepsie-Liga in Wien 3. bis 6. Mai 2017 im Austria Center Vienna).
  • Roelz R, Scheiwe C, Kraeutle R, Jabbarli R, Coenen VA, Reinacher P: Stereotactic Clearance of Subarachnoid Hemorrhage Reduces Mortality and Delayed Cerebral Infarction. A Matched Cohort Study. 2017 (26th European Stroke Conference from 24–26 May 2017 in Berlin, Germany.).
  • Steiert C: Poster: Cumulative surgical morbidity in patients with multiple cerebellar and medullary hemangioblastomas. 2017 (DGNC-Jahrestagung 15.05.2017 in Magdeburg).
  • Steiert C, Schmucker M, Rölz R, Shah M, Mader I, Coenen VA, Reinacher P: Stereotactic implantation of cysto-ventricular catheters in patients with craniopharyngeomas: An effective method to control cyst size and improve conditions for radiotherapy. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie 2017, Magdeburg).
Konferenzbeiträge:
  • Delev D, Haaker G, Steinhoff BJ, Scheiwe C, Nakagawa JM, Schulze-Bonhage A, Zentner J: Insular resections for drug-resistant epilepsy: results and prognostic factors. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); Magdeburg; 20170514-20170517), Deutsche Gesellschaft für Neurochirurgie; Society of British Neurological Surgeons (Hrsg). : http://DOCDI.19.03 /20170609/
  • Haaker G, Delev D, Steinhoff BJ, Nakagawa JM, Scheiwe C, Schulze-Bonhage A, Zentner J: A second chance - reoperation after failed surgical treatment for extratemporal epilepsy. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); Magdeburg; 20170514-20170517), Deutsche Gesellschaft für Neurochirurgie; Society of British Neurological Surgeons (Hrsg). : http://DOCDI.19.02 /20170609/
  • Heiland DH, Gaebelein A, Borries M, Wörner J, Carro MS, Weber S, Mader I, Schnell O: Metb-12. Metabolic re-progrmming mediates bidirectional shift between transcription subclasses and drives tumor heterogeneity. Neuro-oncology, 2017; 19 (11) Suppl. 6 (online): vi131 (22nd Annual Scientific Meeting of the Aociety for Neuro-Oncology, San Francisco, USA). : http://doi.org/10.1093/neuonc/nox168.536
  • Heiland DH, Heynckes S, Mader I, Pfeifer D, Prinz M, Delev D, Schnell O: Immu-47. Analysis of immune response and stat3 pathway of de-novo and recurrent glioblastoma multiforme. Neuro-oncology, 2017; 19 (11) Suppl. 6 (online): vi123 (22nd Annual Scientific Meeting of the Aociety for Neuro-Oncology, San Francisco, USA). : http://doi.org/10.1093/neuonc/nox168.505
  • Jarc N, Scheiwe C, Grauvogel J: Venous air embolism and related intra- and postoperative complications in semi-sitting position for posterior cranial fossa surgery. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); Magdeburg; 20170514-20170517), Deutsche Gesellschaft für Neurochirurgie; Society of British Neurological Surgeons (Hrsg). : http://DOCMi.19.06 /20170609/
  • Masalha W, Heiland DH, Jimenez PF, Delev D, Haaker JG, Schnell O, Scheiwe C, Grauvogel J: Atypical meningioma: Progression-free survival of 161 cases with surgery only versus surgery and radiotherapy. 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); Magdeburg; 20170514-20170517), Deutsche Gesellschaft für Neurochirurgie; Society of British Neurological Surgeons (Hrsg). : http://DOCMO.27.06 /20170609/
  • Pschibul A, Gierthmühlen M, Müller-Felber W, Korinthenberg R: Poster: Progressive Radial Motor Neuropathy Due to a Perineurioma in an Adolescent Girl: Case Report. 2017; 48 Suppl. S01: 1-45 (Neuropediatrics 2017), Georg Thieme Verlag KG Stuttgart · New York (Hrsg). : http://dx.doi.org/10.1055/s-0037-1603000
  • Shah M, Reinhard M, Rölz R, Scheiwe C, Jabbarli R: Asymmetry of the anterior cerebral artery in patients with aneurysmal subarachnoid hemorrhage: The phantom menace! 2017 (68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); Magdeburg; 20170514-20170517), Deutsche Gesellschaft für Neurochirurgie; Society of British Neurological Surgeons (Hrsg). : http://DOCMi.01.08 /20170609/

Besondere wissenschaftliche Aktivitäten

Preise / Ehrungen:
  • Gierthmuehlen M, Aguirre D, Koenne N, Plachta D: Neuromodulation against resistant hypertension: Efficiency of ECG-synchronized selective vagal nerve stimulation in an acute sheep model., Posterpreis "Interventionelle Neuromodulation" der DGNC 2017, http://www.dgnc.de/2017/programm/preise.html, 13.06.2017 bis 12.06.2018.
  • Shah MJ: Ehrenurkunde der Beuth Hochschule für Technik in Berlin , hervorragende Masterprüfung, 30.11.2017 bis 30.11.2018.

Abschlussarbeiten

Habilitationen
  • PD Dr. Ulrich Hubbe: Neue Techniken zur Minimierung des Operationstraumas in der Wirbelsäulenchirurgie., 2017.
Promotionen
  • Cand. Med. Karin Gau: Folgt., 2017.
Master
  • Jose, Maria: Faculty of Natural Science, University of Magdeburg., 2017.
  • Shah, Mukesch Johannes: Integration von Navigationssystemen in Web- und JavaScript-Applikationen (Beuth Hochschule für Technik Berlin)., 2017.
Bachelor
  • Hudek, Anna: Faculty of Biology, University of Freiburg., 2017.
  • Mann, Lukas: Faculty of Medical and Life Science, University of Furtwangen., 2017.