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 Forschungsbericht für das Jahr 2017

Department Chirurgie

Klinik für Urologie

Prof. Dr. med. Ulrich Wetterauer

Hugstetterstraße 55
79106 Freiburg
Tel: +49 761 270 28 910
Email sekretariat.urologie@uniklinik-freiburg.de

Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Ulrich Wetterauer
  • Prof. Dr. Wolfgang Schultze-Seemann
  • PD Dr. Alexander Frankenschmidt
  • PD Dr. Cordula Jilg
  • Dr. Arndt Katzenwadel
  • Dr. Christian Leiber
  • Prof. Dr. Dr. med. univ. Arkadiusz Miernik
  • PD Dr. Martin Schönthaler
  • Dr. Christian Fahr
  • Dr. Katrin Friedl
  • Dr. Jonas Fritzsche
  • Dr. Malte Krönig
  • Dr. Katrin Spiess
  • Dr. Fabian Adams
  • Carmen Biegel
  • Dr. Moritz von Büren
  • Franz Friedrich Dreßler
  • Dr. Kathrin Grupp
  • Andrea Gühna
  • Dr. Simon Hein
  • Dr. Carmen Kremmler
  • Dr. Philippe-Fabian Müller
  • Dr. Kathrin Reichel (geb. Schaal)
  • Dr. Daniel Schlager
  • Dr. Dominik Schöb
  • Dr. Konrad Wilhelm
  • Dr. Marta Michalska
  • PD Dr. Philipp Wolf
Einträge in der Rubrik "Who is Who"

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Adams F, Qiu T, Mark A, Fritz B, Kramer L, Schlager D, Wetterauer U, Miernik A, Fischer P: Soft 3D-Printed Phantom of the Human Kidney with Collecting System. Ann Biomed Eng, 2017; 45 (4): 963-972. : http://dx.doi.org/10.1007/s10439-016-1757-5
  • Adams F, Schoelly R, Schlager D, Schoenthaler M, Schoeb DS, Wilhelm K, Hein S, Wetterauer U, Miernik A: Algorithm-Based Motion Magnification for Video Processing in Urological Laparoscopy. J Endourol, 2017; 31 (6): 583-587. : http://dx.doi.org/10.1089/end.2016.0882
  • Ardelt PU, Cederqvist M, Barth M, Frankenschmidt A: The SIGHT questionnaire: A novel assessment tool for Satisfaction In Genital Hypospadias Treatment. J Pediatr Urol, 2017; 13 (1): 33.e1-33.e8. : http://dx.doi.org/10.1016/j.jpurol.2016.10.011
  • Benndorf M, Hahn F, Krönig M, Jilg CA, Krauss T, Langer M, Dovi-Akue P: Diagnostic performance and reproducibility of T2w based and diffusion weighted imaging (DWI) based PI-RADSv2 lexicon descriptors for prostate MRI. Eur J Radiol, 2017; 93: 9-15. : http://dx.doi.org/10.1016/j.ejrad.2017.05.015
  • Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, Littleford RC, Gilchrist M, Colhoun HM, Shore AC, Khan F, Strain WD: The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 2017; 16 (1): 114-114. : http://dx.doi.org/10.1186/s12933-017-0594-7
  • Drendel V, Heckelmann B, Chen CY, Weisser J, Espadas G, Schell C, Sabido E, Werner M, Jilg CA, Schilling O: Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an Oncotarget, 2017; 8 (59): 100066-100078. : http://dx.doi.org/10.18632/oncotarget.21929
  • Dressler FF, Bodi I, Menza M, Moss R, Bugger H, Bode C, Behrends JC, Seemann G, Odening KE: Interregional electro-mechanical heterogeneity in the rabbit myocardium. Prog Biophys Mol Bio, 2017; 130 (Pt B): 344-355. : http://dx.doi.org/10.1016/j.pbiomolbio.2017.06.016
  • Gratzke C, Barber N, Speakman MJ, Berges R, Wetterauer U, Greene D, Sievert KD, Chapple CR, Patterson JM, Fahrenkrug L, Schoenthaler M, Sonksen J: Prostatic urethral lift vs transurethral resection of the prostate: 2-year results of the BPH6 prospective, multicentre, randomized study. Bju Int, 2017; 119 (5): 767-775. : http://dx.doi.org/10.1111/bju.13714
  • Hein S, Schoenthaler M, Wilhelm K, Schlager D, Vach W, Wetterauer U, Miernik A: Ultralow Radiation Exposure During Flexible Ureteroscopy in Patients With Nephrolithiasis-How Far Can We Go? Urology, 2017; 108: 34-39. : http://dx.doi.org/10.1016/j.urology.2017.06.016
  • Jilg CA, Drendel V, Rischke HC, Beck T, Vach W, Schaal K, Wetterauer U, Schultze-Seemann W, Meyer PT: Diagnostic Accuracy of Ga-68-HBED-CC-PSMA-Ligand-PET/CT before Salvage Lymph Node Dissection for Recurrent Prostate Cancer. Theranostics, 2017; 7 (6): 1770-1780. : http://dx.doi.org/10.7150/thno.18421
  • Kernbichl S, Reiter M, Adams F, Vagin S, Rieger B: CO2-Controlled One-Pot Synthesis of AB, ABA Block, and Statistical Terpolymers from beta-Butyrolactone, Epoxides, and CO2. J Am Chem Soc, 2017; 139 (20): 6787-6790. : http://dx.doi.org/10.1021/jacs.7b01295
  • Kronig M, Haverkamp C, Schulte A, Heinicke L, Schaal K, Drendel V, Werner M, Wetterauer U, Schultze-Seemann W, Jilg CA: Diabetes and beta-adrenergic blockage are risk factors for metastatic prostate cancer. World J Surg Oncol, 2017; 15 (1) (online): 50-50. : http://dx.doi.org/10.1186/s12957-017-1117-4
  • Kunath F, Schmidt S, Krabbe LM, Miernik A, Dahm P, Cleves A, Walther M, Kroeger N: Partial nephrectomy versus radical nephrectomy for clinical localised renal masses. Cochrane Db Syst Rev, 2017; 5 (online): CD012045. : http://dx.doi.org/10.1002/14651858.CD012045.pub2
  • Michalska M, Katzenwadel A, Wolf P: Methadone as a "Tumor Theralgesic" against Cancer. Front Pharmacol, 2017; 8 (online): 733-733. : http://dx.doi.org/10.3389/fphar.2017.00733
  • Miernik A, Hein S, Wilhelm K, Schoenthaler M: [Urinary Stone Analysis - What does the Future Hold in Store?] Aktuel Urol, 2017; 48 (2): 127-131. : http://dx.doi.org/10.1055/s-0042-120468
  • Noll T, Schultze-Seemann S, Kuckuck I, Michalska M, Wolf P: Synergistic cytotoxicity of a prostate cancer-specific immunotoxin in combination with the BH3 mimetic ABT-737. Cancer Immunol Immun, 2017. : http://dx.doi.org/10.1007/s00262-017-2097-5 (in Druck)
  • Pentek Q, Hein S, Miernik A, Reiterer A: Image-based 3D surface approximation of the bladder using structure-from-motion for enhanced cystoscopy based on phantom data. Biomed Eng-biomed Te, 2017 (online). : http://dx.doi.org/10.1515/bmt-2016-0185 (in Druck)
  • Qiu T, Adams F, Palagi S, Melde K, Mark A, Wetterauer U, Miernik A, Fischer P: Wireless Acoustic-Surface Actuators for Miniaturized Endoscopes. Acs Appl Mater Inter, 2017; 9 (49): 42536-42543. : http://dx.doi.org/10.1021/acsami.7b12755
  • Rauscher I, Eiber M, Jilg CA, Gschwend JE, Maurer T: [PSMA-radioguided surgery in localized recurrent prostate cancer : Current and future aspects]. Urologe, 2017; 56 (1): 18-23. : http://dx.doi.org/10.1007/s00120-016-0275-2
  • Schiller F, Fechter T, Zamboglou C, Chirindel A, Salman N, Jilg CA, Drendel V, Werner M, Meyer PT, Grosu AL, Mix M: Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation. EJNMMI Phys, 2017; 4 (1): 21-21. : http://dx.doi.org/10.1186/s40658-017-0188-1
  • Schlager D, Hein S, Obaid MA, Wilhelm K, Miernik A, Schoenthaler M: Performance of single-use Flexor(R)Vue vs. reusable BoaVision ureteroscope for visualization of calyces and stone extraction in an artificial kidney model. J Endourol, 2017; 31 (11): 1139-1144. : http://dx.doi.org/10.1089/end.2017.0454
  • Schlager D, Maas M, Hein S, Adams F, Schoenthaler M, Spittau B, Wetterauer U, Miernik A: Is Endoscopic Vasectomy Just a Dream?: An ex vivo Study on Feasibility and Reliability of Endoluminal Occlusion of Porcine Vas Deferens. Urol Int, 2017; 99 (4): 467-475. : http://dx.doi.org/10.1159/000478790
  • Schneidewind L, Kranz J, Schlager D, Barski D, Muhlsteadt S, Grabbert M, Queissert F, Frank T, Pelzer AE: Mulitcenter study on antibiotic prophylaxis, infectious complications and risk assessment in TUR-P. Cent European J Urol, 2017; 70 (1): 112-117. : http://dx.doi.org/10.5173/ceju.2017.941
  • Schoeb DS, Schlager D, Boeker M, Wetterauer U, Schoenthaler M, Herrmann TRW, Miernik A: Surgical therapy of prostatitis: a systematic review. World J Urol, 2017; 35 (11): 1659-1668. : http://dx.doi.org/10.1007/s00345-017-2054-0
  • Schoeb DS, Schoenthaler M, Schlager D, Petzold R, Richter K, Grunwald I, Wetterauer U, Miernik A, Hein S: New for Old-Coagulum Lithotomy vs a Novel Bioadhesive for Complete Removal of Stone Fragments in a Comparative Study in an Ex Vivo Porcine Model. J Endourol, 2017; 31 (6): 611-616. : http://dx.doi.org/10.1089/end.2017.0125
  • Schoenthaler M, Hein S, Seitz C, Turk C, Danuser H, Vach W, Miernik A: The stone surgeon in the mirror: how are German-speaking urologists treating large renal stones today? World J Urol, 2017. : http://dx.doi.org/10.1007/s00345-017-2148-8 (in Druck)
  • Weir-McCall JR, Khan F, Cassidy DB, Thakur A, Summersgill J, Matthew SZ, Adams F, Dove F, Gandy SJ, Colhoun HM, Belch JJ, Houston JG: Effects of inaccuracies in arterial path length measurement on differences in MRI and tonometry measured pulse wave velocity. Bmc Cardiovasc Disor, 2017; 17 (1): 118-118. : http://dx.doi.org/10.1186/s12872-017-0546-x
  • Wieser G, Popp I, Christian Rischke H, Drendel V, Grosu AL, Bartholoma M, Weber WA, Mansi R, Wetterauer U, Schultze-Seemann W, Meyer PT, Jilg CA: Diagnosis of recurrent prostate cancer with PET/CT imaging using the gastrin-releasing peptide receptor antagonist 68Ga-RM2: Preliminary results in patients with negative or inconclusive [18F]Fluoroethylcholine-PET/CT. Eur J Nucl Med Mol I, 2017; 44 (9): 1463-1472. : http://dx.doi.org/10.1007/s00259-017-3702-8
  • Zamboglou C, Drendel V, Jilg CA, Rischke HC, Beck TI, Schultze-Seemann W, Krauss T, Mix M, Schiller F, Wetterauer U, Werner M, Langer M, Bock M, Meyer PT, Grosu AL: Comparison of 68Ga-HBED-CC PSMA-PET/CT and multiparametric MRI for gross tumour volume detection in patients with primary prostate cancer based on slice by slice comparison with histopathology. Theranostics, 2017; 7 (1): 228-237. : http://dx.doi.org/10.7150/thno.16638
  • Stoykow C, Huber-Schumacher S, Almanasreh N, Jilg C, Ruf J: Strong PSMA Radioligand Uptake by Rectal Carcinoma: Who Put the "S" in PSMA? Clin Nucl Med, 2017; 42 (3): 225-226. : http://dx.doi.org/10.1097/RLU.0000000000001484
  • Wilhelm K, Schultze-Seemann W, Miernik A: Complete Occlusion of a Subcutaneous Pyelovesical Bypass Graft (Detour(R) System) Caused by Uric Acid Stone Formation. Urol Int, 2017; 98: 483-485. : http://dx.doi.org/10.1159/000366140
Kurzbeiträge / short communications:
  • Krafft C *, Wilhelm K *, Eremin A, Nestel S, von Bubnoff N, Schultze-Seemann W, Popp J, Nazarenko I: A specific spectral signature of serum and plasma-derived extracellular vesicles for cancer screening. Nanomed-nanotechnol, 2017; 13 (3): 835-841. : http://dx.doi.org/10.1016/j.nano.2016.11.016
Sonstige Publikationen:
  • Gross AJ, Rassweiler J, Sievert KD, Miernik A, Westphal J, Leyh H, Herrmann TR, Olbert P, Hacker A, Bachmann A, Homberg R, Klein J, Schoenthaler M, Netsch C: [Ureterorenoscopy]. Urologe, 2017; 56 (3) : 395-404. : http://dx.doi.org/10.1007/s00120-017-0333-4
  • Leiber C: [Erectile dysfunction : Current diagnostics and treatment]. Urologe, 2017; 56 (4) : 519-529. : http://dx.doi.org/10.1007/s00120-017-0355-y
  • Miernik A: [Management for unilateral ureteric-pelvic junction obstruction in children less than two years of age]. Urologe, 2017; 56 (9) : 1178-1181. : http://dx.doi.org/10.1007/s00120-017-0466-5
  • Miernik A, Sievert KD, Herrmann TRW, Netsch C, Rassweiler JJ, Leyh H, Westphal J, Bachmann A, Hacker A, Homberg R, Klein JT, Olbert PJ, Schoeb DS, Gross AJ: [Surgical positioning techniques in urology : Tips and tricks]. Urologe, 2017: 1193-1206. : http://dx.doi.org/10.1007/s00120-017-0467-4

Besondere wissenschaftliche Aktivitäten



  • Prof. Dr. Mustafa Kumru, Faith Universität Istanbul, Türkei, Istanbul, Forschung auf dem Gebiet der Raman-Spektroskopie, 01.10.2017 bis 25.03.2018
  • Dr. med. Moaaz Abdulghani Obaid, Saudi-Arabien, Gastarzt zur Facharztausbildung für Urologie, 15.05.2014 bis 30.11.2018