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Wissenschaftliche Publikationen
Originalarbeiten in wissenschaftlichen
Fachzeitschriften:
- Bécart S, Balancio AJ, Charvet C, Feau S, Sedwick CE, Altman A: Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity, 2008; 29 (5): 704-719. : http://dx.doi.org/10.1016/j.immuni.2008.08.015
- Bennett HL, Brummer T, Jeanes A, Yap AS, Daly RJ: Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis. Oncogene, 2008; 27 (19): 2693-2704. : http://dx.doi.org/10.1038/sj.onc.1210928
- Borner C, Bedini A, Hollt V, Kraus J: Analysis of promoter regions regulating basal and interleukin-4-inducible expression of the human CB1 receptor gene in T lymphocytes. Mol Pharmacol, 2008; 73 (3): 1013-1019. : http://dx.doi.org/10.1124/mol.107.042945
- Borner C, Kraus J, Bedini A, Schraven B, Hollt V: T-cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional mu-opioid receptors. Mol Pharmacol, 2008; 74 (2): 496-504. : http://dx.doi.org/10.1124/mol.108.046029
- Brummer T, Larance M, Herrera Abreu MT, Lyons RJ, Timpson P, Emmerich CH, Fleuren ED, Lehrbach GM, Schramek D, Guilhaus M, James DE, Daly RJ: Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. Embo J, 2008; 27 (17): 2305-2316.
- Brummer TH, Seppala TT, Harkki PS: National learning curve for laparoscopic hysterectomy and trends in hysterectomy in Finland 2000-2005. Hum Reprod, 2008; 23 (4): 840-845. : http://dx.doi.org/10.1093/humrep/den006
- Bühler P, Wolf P, Gierschner D, Schaber I, Katzenwadel A, Schultze-Seemann W, Wetterauer U, Tacke M, Swamy M, Schamel WW, Elsässer-Beile U: A bispecific diabody directed against prostate-specific membrane antigen and CD3 induces T-cell mediated lysis of prostate cancer cells. Cancer Immunol Immun, 2008; 57 (1): 43-52. : http://dx.doi.org/10.1007/s00262-007-0348-6
- Conus S, Perozzo R, Reinheckel T, Peters C, Scapozza L, Yousefi S, Simon HU: Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. J Exp Med, 2008; 205 (3): 685-698. : http://dx.doi.org/10.1084/jem.20072152
- Denayer T, Locker M, Borday C, Deroo T, Janssens S, Hecht A, van Roy F, Perron M, Vleminckx K: Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes. Stem Cells, 2008; 26 (8): 2063-2074. : http://dx.doi.org/10.1634/stemcells.2007-0900
- Denayer T, Locker M, Borday C, Deroo T, Janssens S, Hecht A, van Roy F, Perron M, Vleminckx K: Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes. Stem Cells, 2008; 26 (8): 2063-2074. : http://dx.doi.org/10.1634/stemcells.2007-0900
- Dzietko M, Boos V, Sifringer M, Polley O, Gerstner B, Genz K, Endesfelder S, Borner C, Jacotot E, Chauvier D, Obladen M, Buhrer C, Felderhoff-Mueser U: A critical role for Fas/CD-95 dependent signaling pathways in the pathogenesis of hyperoxia-induced brain injury. Ann Neurol, 2008; 64 (6): 664-673. : http://dx.doi.org/10.1002/ana.21516
- Funkelstein L, Toneff T, Hwang SR, Reinheckel T, Peters C, Hook V: Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression. J Neurochem, 2008; 106 (1): 384-391. : http://dx.doi.org/10.1111/j.1471-4159.2008.05408.x
- Funkelstein L, Toneff T, Mosier C, Hwang SR, Beuschlein F, Lichtenauer UD, Reinheckel T, Peters C, Hook V: Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, {beta}-Endorphin, and {alpha}-MSH, Illustrated by Protease Gene Knockout and Expression. J Biol Chem, 2008; 283 (51): 35652-35659. : http://dx.doi.org/10.1074/jbc.M709010200
- Gotschel F, Kern C, Lang S, Sparna T, Markmann C, Schwager J, McNelly S, von Weizsacker F, Laufer S, Hecht A, Merfort I: Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and Exp Cell Res, 2008; 314 (6): 1351-1366. : http://dx.doi.org/10.1016/j.yexcr.2007.12.015
- Götschel F, Kern C, Lang S, Sparna T, Markmann C, Schwager J, McNelly S, von Weizsäcker F, Laufer S, Hecht A, Merfort I: Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis. Exp Cell Res, 2008; 314 (6): 1351-1366. : http://dx.doi.org/10.1016/j.yexcr.2007.12.015
- Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT: The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol, 2008; 9 (8): 857-865. : http://dx.doi.org/10.1038/ni.1636
- Harder J, Opitz OG, Brabender J, Olschewski M, Blum HE, Nomoto S, Usadel H: Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver. Int J Cancer, 2008; 122 (12): 2800-2804. : http://dx.doi.org/10.1002/ijc.23433
- Horkay F, Basser PJ, Hecht AM, Geissler E: Insensitivity to salt of assembly of a rigid biopolymer aggrecan. Phys Rev Lett, 2008; 101 (6): 068301-068301.
- Horkay F, Basser PJ, Hecht AM, Geissler E: Gel-like behavior in aggrecan assemblies. J Chem Phys, 2008; 128 (13): 135103-135103. : http://dx.doi.org/10.1063/1.2884350
- Jiang X, Zaitseva E, Schmidt M, Siebert F, Engelhard M, Schlesinger R, Ataka K, Vogel R, Heberle J: Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy. P Natl Acad Sci Usa, 2008; 105 (34): 12113-12117. : http://dx.doi.org/10.1073/pnas.0802289105
- Kabitz HJ, Sonntag F, Walker D, Schwoerer A, Walterspacher S, Kaufmann S, Beuschlein F, Seufert J, Windisch W: Diabetic polyneuropathy is associated with respiratory muscle impairment in type 2 diabetes. Diabetologia, 2008; 51 (1): 191-197.
- Lichtenauer UD, Shapiro I, Geiger K, Quinkler M, Fassnacht M, Nitschke R, Rückauer KD, Beuschlein F: Side population does not define stem cell-like cancer cells in the adrenocortical carcinoma cell line NCI h295R. Endocrinology, 2008; 149 (3): 1314-1322. : http://dx.doi.org/10.1210/en.2007-1001
- Mahalingam M, Martinez-Mayorga K, Brown MF, Vogel R: Two protonation switches control rhodopsin activation in membranes. P Natl Acad Sci Usa, 2008; 105 (46): 17795-17800. : http://dx.doi.org/10.1073/pnas.0804541105
- Manolopoulou J, Bielohuby M, Caton SJ, Gomez-Sanchez CE, Renner-Mueller I, Wolf E, Lichtenauer UD, Beuschlein F, Hoeflich A, Bidlingmaier M: A highly sensitive immunofluorometric assay for the measurement of aldosterone in small sample volumes: validation in mouse serum. J Endocrinol, 2008; 196 (2): 215-224. : http://dx.doi.org/10.1677/JOE-07-0134
- Pardo J, Wallich R, Martin P, Urban C, Rongvaux A, Flavell RA, Müllbacher A, Borner C, Simon MM: Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs. Cell Death Differ, 2008; 15 (3): 567-579. : http://dx.doi.org/10.1038/sj.cdd.4402289
- Pardo J, Wallich R, Martin P, Urban C, Rongvaux A, Flavell RA, Mullbacher A, Borner C, Simon MM: Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs. Cell Death Differ, 2008; 15 (3): 567-579. : http://dx.doi.org/10.1038/sj.cdd.4402289
- Ryppa C, Mann-Steinberg H, Fichtner I, Weber H, Satchi-Fainaro R, Biniossek ML, Kratz F: In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3. Bioconjugate Chem, 2008; 19 (7): 1414-1422. : http://dx.doi.org/10.1021/bc800117r
- Schilling O, Overall CM: Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites. Nat Biotechnol, 2008; 26 (6): 685-694. : http://dx.doi.org/10.1038/nbt1408
- Schurigt U, Sevenich L, Vannier C, Gajda M, Schwinde A, Werner F, Stahl A, von Elverfeldt D, Becker AK, Bogyo M, Peters C, Reinheckel T: Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model. Biol Chem, 2008; 389 (8): 1067-1074. : http://dx.doi.org/10.1515/BC.2008.115
- Schuy S, Faiss S, Yoder NC, Kalsani V, Kumar K, Janshoff A, Vogel R: Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study. J Phys Chem B, 2008; 112 (28): 8250-8256. : http://dx.doi.org/10.1021/jp800711j
- Schwinté P, Foerstendorf H, Hussain Z, Gärtner W, Mroginski MA, Hildebrandt P, Siebert F: FTIR study of the photoinduced processes of plant phytochrome phyA using isotope-labeled bilins and density functional theory calculations. Biophys J, 2008; 95 (3): 1256-1267. : http://dx.doi.org/10.1529/biophysj.108.131441
- Standfuss J, Zaitseva E, Mahalingam M, Vogel R: Structural impact of the E113Q counterion mutation on the activation and deactivation pathways of the G protein-coupled receptor rhodopsin. J Mol Biol, 2008; 380 (1): 145-157. : http://dx.doi.org/10.1016/j.jmb.2008.04.055
- Taitsman LA, Altman DT, Hecht AC, Pedlow FX: Complications of cervical halo-vest orthoses in elderly patients. Orthopedics, 2008; 31 (5): 446-446.
- Urban C, Rheme C, Maerz S, Berg B, Pick R, Nitschke R, Borner C: Apoptosis induced by Semliki Forest virus is RNA replication dependent and mediated via Bak. Cell Death Differ, 2008; 15 (9): 1396-1407. : http://dx.doi.org/10.1038/cdd.2008.61
- Urban C, Rhême C, Maerz S, Berg B, Pick R, Nitschke R, Borner C: Apoptosis induced by Semliki Forest virus is RNA replication dependent and mediated via Bak. Cell Death Differ, 2008; 15 (9): 1396-1407. : http://dx.doi.org/10.1038/cdd.2008.61
- Vasiljeva O, Korovin M, Gajda M, Brodoefel H, Bojic L, Krüger A, Schurigt U, Sevenich L, Turk B, Peters C, Reinheckel T: Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice. Oncogene, 2008; 27 (30): 4191-4199. : http://dx.doi.org/10.1038/onc.2008.59
- Vogel R, Mahalingam M, Lüdeke S, Huber T, Siebert F, Sakmar TP: Functional role of the "ionic lock"-an interhelical hydrogen-bond network in family A heptahelical receptors. J Mol Biol, 2008; 380 (4): 648-655. : http://dx.doi.org/10.1016/j.jmb.2008.05.022
- Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsäcker F, Merfort I, Maurer U, Strasser A, Borner C: Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 2008; 48 (6): 1942-1953. : http://dx.doi.org/10.1002/hep.22541
- Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsacker F, Merfort I, Maurer U, Strasser A, Borner C: Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 2008; 48 (6): 1942-1953. : http://dx.doi.org/10.1002/hep.22541
- Wolf P, Alt K, Bühler P, Katzenwadel A, Wetterauer U, Tacke M, Elsässer-Beile U: Anti-PSMA immunotoxin as novel treatment for prostate cancer? High and specific antitumor activity on human prostate xenograft tumors in SCID mice. Prostate, 2008; 68 (2): 129-138. : http://dx.doi.org/10.1002/pros.20684
- Zeiser R, Leveson-Gower DB, Zambricki EA, Kambham N, Beilhack A, Loh J, Hou JZ, Negrin RS: Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood, 2008; 111 (1): 453-462.
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