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 Forschungsbericht für das Jahr 2018

Physiologisches Institut

Hermann-Herder-Str. 7
79104 Freiburg i. Br.
Tel: +49 761 203-5176/5150 Fax: +49 761 203-5191/5204
http://www.physiologie.uni-freiburg.de


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Bernd Fakler
  • Prof. Dr. emer. Hermann Antoni
  • Prof. Dr. Jan Behrends
  • Prof. Dr. Gisa Fleckenstein-Grün
  • PD Dr. Jörg Weirich
  • Dr. Detlef Bentrop
  • Dr. Henrike Berkefeld
  • Dr. Wolfgang Bildl
  • PD Dr. Akos Kulik
  • Dr. Uwe Schulte
  • Dr. Gerd Zolles
  • Dr. Jochen Schwenk
Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Direct recordings from presynaptic elements and dendrites
  • Excitatory and inhibitory synaptic transmission in the mammalian central nervous system
  • Functional significance of K+ channels in various types of cell (neurons, sensory hair cells in the inner ear)
  • GABAergic interneurons
  • Glutamate receptors of the AMPA and NMDA subtype
  • Ion channels
  • Ion transport
  • Mechanisms of transmitter release
  • Molecular mechanisms underlying function and regulation of ion channels (K+, Ca2+) and other membrane proteins (prestin)
  • NMR-based structure analysis of functional domains of membrane proteins (in particular ion channel proteins)
  • Protein-protein interaction in ion channels
  • Proteom analysis of the microdomains associated with membrane proteins including ion channels, transporters and GPCRs
  • Somatodendritic integration of synaptic signals
  • Voltage-gated ion channels (Na+, K+, Ca2+)

Finanzierung

  • Fördermittel der Tinnitus GmbH

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Lykouras MV, Tsika AC, Lichière J, Papageorgiou N, Coutard B, Bentrop D, Spyroulias GA: NMR study of non-structural proteins-part III: 1H, 13C, 15N backbone and side-chain resonance assignment of macro domain from Chikungunya virus (CHIKV) J Biomol Nmr, 2018; 12 (1): 31-35. : http://doi.org/10.1007/s12104-017-9775-2

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten