Forschungsbericht für das Jahr 1900-2019

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Bernardi S, Continenza MA, Al-Ahmad A, Karygianni L, Follo M, Filippi A, Macchiarelli G: Streptococcus spp. and Fusobacterium nucleatum in tongue dorsum biofilm from halitosis patients: a fluorescence in situ hybridization (FISH) and confocal laser scanning microscopy (CLSM study New Microbiol, 2019; 42: 108-113.
  • Burchard T, Karygianni L, Hellwig E, Follo M, Wrbas T, Wittmer A, Vach K, Al-Ahmad A: Inactivation of oral biofilms using visible light and water-filtered infrared A radiation and indocyanine green. Future Med Chem, 2019; 11 (14): 1721-1739. : http://dx.doi.org/10.4155/fmc-2018-0522
  • Cieplik1 F, Jakubovics NS, Buchalla1 W, Maisch T, Hellwig E, Al-Ahmad A: Resistance Toward Chlorhexidine in Oral Bacteria – Is There Cause for Concern? Front Microbiol, 2019; 10 (587) (online).
  • Karygianni L, Cecere M, Argyropoulou A, Hellwig E, Skaltsounis AL, Wittmer A, Tchorz JP, Al-Ahmad A: Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth. Bmc Complem Altern M, 2019; 19 (1): 51-51. : http://dx.doi.org/10.1186/s12906-019-2461-4
  • Kruse AB, Akakpo DL, Maamar R, Woelber JP, Al-Ahmad A, Vach K, Ratka-Krueger P: Trehalose powder for subgingival air-polishing during periodontal maintenance therapy: A randomized controlled trial. J Periodontol, 2019; 90 (3): 263-270. : http://dx.doi.org/10.1002/JPER.17-0403
  • P W Doll, A Al-Ahmad, A Bacher, A Muslija, R Thelen, L Hahn, R Ahrens, B Spindler, A E Guber1: Fabrication of silicon nanopillar arrays by electron beam lithography and reactive ion etching for advanced bacterial adhesion studies Mater Res Express, 2019; 6 (065402) (online).
  • Widyaya VT, Muller C, Al-Ahmad A, Lienkamp K: Three-Dimensional, Bifunctional Microstructured Polymer Hydrogels Made from Polyzwitterions and Antimicrobial Polymers. Langmuir, 2019; 35 (5): 1211-1226. : http://dx.doi.org/10.1021/acs.langmuir.8b03410
  • Woelber JP, Gartner M, Breuninger L, Anderson A, Konig D, Hellwig E, Al-Ahmad A, Vach K, Dotsch A, Ratka-Kruger P, Tennert C: The influence of an anti-inflammatory diet on gingivitis. A randomized controlled trial. J Clin Periodontol, 2019; 46 (4): 481-490. : http://dx.doi.org/10.1111/jcpe.13094
  • Al-Ahmad A, Muzafferiy F, Anderson AC, Wolber JP, Ratka-Kruger P, Fretwurst T, Nelson K, Vach K, Hellwig E: Shift of microbial composition of peri-implantitis-associated oral biofilm as revealed by 16S rRNA gene cloning. J Med Microbiol, 2018; 67 (3): 332-340. : http://dx.doi.org/10.1099/jmm.0.000682
  • Anderson AC, Andisha H, Hellwig E, Jonas D, Vach K, Al-Ahmad A: Antibiotic Resistance Genes and Antibiotic Susceptibility of Oral Enterococcus faecalis Isolates Compared to Isolates from Hospitalized Patients and Food Adv Exp Med Biol, 2018; 1057: 47-62. : https://doi.org/10.1007/5584_2017_53
  • Anderson AC, Rothballer M, Altenburger MJ, Woelber JP, Karygianni L, Lagkouvardos I, Hellwig E, Al-Ahmad A: In-vivo shift of the microbiota in oral biofilm in response to frequent sucrose consumption. Sci Rep-uk, 2018; 8 (1): 14202-14202. : http://dx.doi.org/10.1038/s41598-018-32544-6
  • Hickl J, Argyropoulou A, Sakavitsi ME, Halabalaki M, Al-Ahmad A, Hellwig E, Aligiannis N, Skaltsounis AL, Wittmer A, Vach K, Karygianni L: Mediterranean herb extracts inhibit microbial growth of representative oral microorganisms and biofilm formation of Streptococcus mutans. Plos One, 2018; 13 (12): e0207574-e0207574. : http://dx.doi.org/10.1371/journal.pone.0207574
  • Hulsdunker J, Ottmuller KJ, Neeff HP, Koyama M, Gao Z, Thomas OS, Follo M, Al-Ahmad A, Prinz G, Duquesne S, Dierbach H, Kirschnek S, Lammermann T, Blaser MJ, Fife BT, Blazar BR, Beilhack A, Hill GR, Hacker G, Zeiser R: Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood, 2018; 131 (16): 1858-1869. : http://dx.doi.org/10.1182/blood-2017-10-812891
  • Kruse AB, Kuerschner AC, Kunze M, Woelber JP, Al-Ahmad A, Wittmer A, Vach K, Ratka-Krueger P: Association between high risk for preterm birth and changes in gingiva parameters during pregnancy-a prospective cohort study. Clin Oral Invest, 2018; 22 (3): 1263-1271. : http://dx.doi.org/10.1007/s00784-017-2209-9
  • Kurowska M, Widyaya VT, Al-Ahmad A, Lienkamp K: Surface-Attached Poly(oxanorbornene) Hydrogels with Antimicrobial and Protein-Repellent Moieties: The Quest for Simultaneous Dual Activity Materials, 2018; 11 (online): 1411.
  • Vlachojannis C, Chrubasik-Hausmann S, Hellwig E, Vach K, Al-Ahmad A.: Activity of preparations from Spilanthes oleracea, propolis, Nigella sativa, and black garlic on different microorganisms involved in oral diseases and on total human salivary bacteria: A pilot study. Phytother Res, 2018; 32: 1992-2001.
  • Altmann B *, Karygianni L *, Al-Ahmad A, Butz F, Bächle M, Erik Adolfsson E, Fürderer T, Courtois N, Palmero P, Follo M, Chevalier J, Steinberg T *, Kohal R *: Assessment of Novel Long-Lasting Ceria-Stabilized Zirconia-Based Ceramics with Different Surface Topographies as Implant Materials Adv Funct Mater, 2017; 27 (40) (online): 1702512. : http://dx.doi.org/10.1002/adfm.201702512
  • Cieplik F, Buchalla W, Hellwig E, Al-Ahmad A, Hiller KA, Maisch T, Karygianni L: Antimicrobial photodynamic therapy as an adjunct for treatment of deep carious lesions-a systematic review. Photodiagn Photodyn, 2017; 18: 54-62. : http://dx.doi.org/10.1016/j.pdpdt.2017.01.005
  • Kurowska M, Eickenscheidt A, Guevara-Solarte DL, Widyaya VT, Marx F, Al-Ahmad A, Lienkamp K: A Simultaneously Antimicrobial, Protein-Repellent, and Cell-Compatible Polyzwitterion Network. Biomacromolecules, 2017; 18 (4): 1373-1386. : http://dx.doi.org/10.1021/acs.biomac.7b00100
  • Luginbühl M, Weinmann W, Al-Ahmad A: Introduction of sample tubes with sodium azide as a preservative for ethyl glucuronide in urine Int J Legal Med, 2017; 131: 1283-1289.
  • Tennert C, Schurig T, Al-Ahmad A, Strobel SL, Kielbassa AM, Wrbas KT: Antimicrobial influence of different root canal filling techniques in experimentally infected human root canals. Quintessence Int, 2017; 48 (4): 273-280. : http://dx.doi.org/10.3290/j.qi.a37129
  • Al-Ahmad A, Auschill TM, Dakhel R, Wittmer A, Pelz K, Heumann C, Hellwig E, Arweiler NB: Prevalence of Candida albicans and Candida dubliniensis in caries-free and caries-active children in relation to the oral microbiota-a clinical study Clin Oral Invest, 2016; 20: 1963-1971.
  • Al-Ahmad A​, Karygianni L​, Schulze Wartenhorst M, Bächle M, Hellwig E, Follo M, Vach K, Han JS​: Bacterial adhesion and biofilm formation on yttria-stabilized, tetragonal zirconia and titanium oral implant materials with low surface roughness - an in situ study J Med Microbiol, 2016; 65: 596-604. : http://dx.doi.org/10.1099/jmm.0.000267
  • Al-Ahmad A, Walankiewicz A, Hellwig E, Follo M, Tennert T, Wittmer A, Karygianni L: Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms Front Microbiol, 2016; 7 (online): 1900. : http://dx.doi.org/10.3389/fmicb.2016.01900
  • Anderson AC, Jonas D, Huber I, Karygianni L, Wölber J, Hellwig E, Arweiler N, Vach K, Wittmer A, Al-Ahmad A: Enterococcus faecalis from Food, Clinical Specimens, and Oral Sites: Prevalence of Virulence Factors in Association with Biofilm Formation Front Microbiol, 2016; 6 (online): 1534. : http://dx.doi.org/10.3389/fmicb.2015.01534
  • Argyropoulou A, Karygianni L, Bartels N, Aligiannis N, Al-Ahmad A, Hellwig E, Wittmer A, Skaltsounis AL: In vitro antimicrobial potential of representative Mediterranean plant extracts against oral microorganisms. Planta Med, 2016; 81 Suppl. 01: S1-S381. : http://dx.doi.org/10.1055/s-0036-1596304
  • Boch T, Tennert C, Vach K, Al-Ahmad A, Hellwig E, Polydorou O: Effect of gaseous ozone on Enterococcus faecalis biofilm-an in vitro study. Clin Oral Invest, 2016; 20 (7): 1733-1739. : http://dx.doi.org/10.1007/s00784-015-1667-1
  • Dorner F, Malek-Luz A, Saar JS, Bonaus S, Al-Ahmad A, Lienkamp K: Synthetic Mimics of Antimicrobial Peptides (SMAMPs) in Layer-by-Layer Architectures – Possibilities and Limitations Macromol Chem Phys, 2016; 217: 2154-2164.
  • Hertel S, Graffy L, Pötschke S, Basche S, Al-Ahmad A, Hoth-Hannig W, Hannig M, Hannig C: Effect of Inula viscosa on the pellicle’s protective properties and initial bioadhesion in-situ Arch Oral Biol, 2016; 71: 87-96. : http://dx.doi.org/10.1016/j.archoralbio.2016.07.006
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms Front Microbiol, 2016; 6 (online): 1529.
  • Schienle S, Al-Ahmad A, Kohal RJ, Bernsmann F, Adolfsson E, Montanaro L, Palmero P, Furderer T, Chevalier J, Hellwig E, Karygianni L: Microbial adhesion on novel yttria-stabilized tetragonal zirconia (Y-TZP) implant surfaces with nitrogen-doped hydrogenated amorphous carbon (a-C:H:N) coatings. Clin Oral Invest, 2016; 20 (7): 1719-1732. : http://dx.doi.org/10.1007/s00784-015-1655-5
  • Vlachojannis C, Al-Ahmad A, Hellwig E, Chrubasik S: Listerine(R) Products: An Update on the Efficacy and Safety. Phytother Res, 2016; 30 (3): 367-373. : http://dx.doi.org/10.1002/ptr.5555
  • Woelber JP, Bremer K, Vach K, Konig D, Hellwig E, Ratka-Kruger P, Al-Ahmad A, Tennert C: An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study. Bmc Oral Health, 2016; 17 (1) (online): 28. : http://dx.doi.org/10.1186/s12903-016-0257-1
  • Al-Ahmad A, Bucher M, Anderson AC, Tennert C, Hellwig E, Wittmer A, Vach K, Karygianni L: Antimicrobial Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (VIS + wIRA) Alters In Situ Oral Biofilms. Plos One, 2015; 10 (7) (online): e0132107. : http://dx.doi.org/10.1371/journal.pone.0132107
  • Dorner F, Boschert D, Schneider A, Hartleb W, Al-Ahmad A, Lienkamp K: Toward Self-Regenerating Antimicrobial Polymer Surfaces Acs Macro Lett, 2015; 4: 1337-1340. : http://dx.doi.org/10.1021/acsmacrolett.5b00686
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms. Front Microbiol, 2015; 6: 1529-1529. : http://dx.doi.org/10.3389/fmicb.2015.01529
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms. Front Microbiol, 2015; 6: 1529-1529. : http://dx.doi.org/10.3389/fmicb.2015.01529
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms. Front Microbiol, 2015; 6: 1529-1529. : http://dx.doi.org/10.3389/fmicb.2015.01529
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms. Front Microbiol, 2015; 6: 1529-1529. : http://dx.doi.org/10.3389/fmicb.2015.01529
  • Karygianni L, Al-Ahmad A, Argyropoulou A, Hellwig E, Anderson AC, Skaltsounis AL: Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms. Front Microbiol, 2015; 6: 1529-1529. : http://dx.doi.org/10.3389/fmicb.2015.01529
  • Karygianni L, Anderson AC, Tennert C, Kollmar K, Altenburger MJ, Hellwig E, Al-Ahmad A: Supplementary sampling of obturation materials enhances microbial analysis of endodontic treatment failures: a proof of principle study. Clin Oral Invest, 2015; 19 (2): 319-327. : http://dx.doi.org/10.1007/s00784-014-1231-4
  • Tennert C, Drews AM, Walther V, Altenburger MJ, Karygianni L, Wrbas KT, Hellwig E, Al-Ahmad A: Ultrasonic activation and chemical modification of photosensitizers enhances the effects of photodynamic therapy against Enterococcus faecalis root-canal isolates. Photodiagn Photodyn, 2015; 12: 244-251. : http://dx.doi.org/10.1016/j.pdpdt.2015.02.002
  • Vlachojannis C, Chrubasik-Hausmann S, Hellwig E, Al-Ahmad A: A Preliminary Investigation on the Antimicrobial Activity of Listerine(R), Its Components, and of Mixtures Thereof. Phytother Res, 2015; 29 (10): 1590-1594. : http://dx.doi.org/10.1002/ptr.5399
  • Zou P, Laird D, Riga EK, Deng Z, Dorner F, Perez-Hernandez H-R, Guevara-Solarte DL, Steinberg T, Al-Ahmad A, Lienkamp K: Antimicrobial and cell-compatible surface-attached polymer networks – how the correlation of chemical structure to physical and biological data leads to a modified mechanism of action J Mater Chem B, 2015; 3: 6224-6238.
  • Abouassi T, Hannig C, Mahncke K, Karygianni L, Wolkewitz M, Hellwig E, Al-Ahmad A: Does human saliva decrease the antimicrobial activity of chlorhexidine against oral bacteria? BMC Res Notes, 2014; 7 (1): 711-711. : http://dx.doi.org/10.1186/1756-0500-7-711
  • Al-Ahmad A, Ameen H, Pelz K, Karygianni L, Wittmer A, Anderson AC, Spitzmuller B, Hellwig E: Antibiotic Resistance and Capacity for Biofilm Formation of Different Bacteria Isolated from Endodontic Infections Associated with Root-filled Teeth. J Endodont, 2014; 40 (2): 223-230. : http://dx.doi.org/10.1016/j.joen.2013.07.023
  • Al-Ahmad A, Zou P, Solarte DL, Hellwig E, Steinberg T, Lienkamp K: Development of a Standardized and Safe Airborne Antibacterial Assay, and Its Evaluation on Antibacterial Biomimetic Model Surfaces. Plos One, 2014; 9 (10): e111357-e111357. : http://dx.doi.org/10.1371/journal.pone.0111357
  • Anderson A, Sanunu M, Schneider C, Clad A, Karygianni L, Hellwig E, Al-Ahmad A: Rapid species-level identification of vaginal and oral lactobacilli using MALDI-TOF MS analysis and 16S rDNA sequencing. Bmc Microbiol, 2014; 14 (online): 312. : http://dx.doi.org/10.1186/s12866-014-0312-5
  • Arweiler NB, Netuschil L, Beier D, Grunert S, Heumann C, Altenburger MJ, Sculean A, Nagy K, Al-Ahmad A, Auschill TM: Action of food preservatives on 14-days dental biofilm formation, biofilm vitality and biofilm-derived enamel demineralisation in situ. Clin Oral Invest, 2014; 18 (3): 829-838. : http://dx.doi.org/10.1007/s00784-013-1053-9
  • Ganter P, Al-Ahmad A, Wrbas KT, Hellwig E, Altenburger MJ: The use of computer-assisted FACE for minimal-invasive caries excavation. Clin Oral Invest, 2014; 18 (3): 745-751. : http://dx.doi.org/10.1007/s00784-013-1022-3
  • Karygianni L, Cecere M, Skaltsounis AL, Argyropoulou A, Hellwig E, Aligiannis N, Wittmer A, Al-Ahmad A: High-Level Antimicrobial Efficacy of Representative Mediterranean Natural Plant Extracts against Oral Microorganisms. Biomed Res Int, 2014; 2014 (online): 839019. : http://dx.doi.org/10.1155/2014/839019
  • Karygianni L, Hellwig E, Al-Ahmad A: Multiplex Fluorescence In Situ Hybridization (M-FISH) and Confocal Laser Scanning Microscopy (CLSM) to Analyze Multispecies Oral Biofilms. Methods Mol Biol, 2014; 1147: 65-72. : http://dx.doi.org/10.1007/978-1-4939-0467-9_5
  • Karygianni L, Ruf S, Follo M, Hellwig E, Bucher M, Anderson AC, Vach K, Al-Ahmad A: Novel Broad-Spectrum Antimicrobial Photoinactivation of In Situ Oral Biofilms by Visible Light plus Water-Filtered Infrared A Appl Environ Microb, 2014; 80 (23): 7324-7336. : http://10.1128/AEM.02490-14
  • Klai S, Altenburger M, Spitzmüller B, Anderson A, Hellwig E, Al-Ahmad A: Antimicrobial Effects of Dental Luting Glass Ionomer Cements on Streptococcus mutans. Sci World J, 2014; 2014 (online): 807086. : http://dx.doi.org/10.1155/2014/807086
  • Tennert C, Feldmann K, Haamann E, Al-Ahmad A, Follo M, Wrbas KT, Hellwig E, Altenburger MJ: Effect of photodynamic therapy (PDT) on Enterococcus faecalis biofilm in experimental primary and secondary endodontic infections. Bmc Oral Health, 2014; 14 (1) (online): 132. : http://dx.doi.org/10.1186/1472-6831-14-132
  • Tennert C, Fuhrmann M, Wittmer A, Karygianni L, Altenburger MJ, Pelz K, Hellwig E, Al-Ahmad A: New Bacterial Composition in Primary and Persistent/Secondary Endodontic Infections with Respect to Clinical and Radiographic Findings. J Endodont, 2014; 40 (5): 670-677. : http://dx.doi.org/10.1016/j.joen.2013.10.005
  • Al-Ahmad A, Tennert C, Karygianni L, Wrbas KT, Hellwig E, Altenburger MJ: Antimicrobial photodynamic therapy using visible light plus water-filtered infrared-A (wIRA). J Med Microbiol, 2013; 62 (Pt 3): 467-473. : http://dx.doi.org/10.1099/jmm.0.048843-0
  • Al-Ahmad A, Wiedmann-Al-Ahmad M, Fackler A, Follo M, Hellwig E, Bachle M, Hannig C, Han JS, Wolkewitz M, Kohal R: In vivo study of the initial bacterial adhesion on different implant materials. Arch Oral Biol, 2013; 58 (9): 1139-1147. : http://dx.doi.org/10.1016/j.archoralbio.2013.04.011
  • Al-Ahmad A *, Laird D, Zou P, Tomakidi P *, Steinberg T *, Lienkamp K *: Nature-Inspired Antimicrobial Polymers – Assessment of Their Potential for Biomedical Applications. Plos One, 2013; 8 (9) (online): e73812. : http://dx.doi.org/10.1371/journal.pone.0073812
  • Anderson AC, Al-Ahmad A, Elamin F, Jonas D, Mirghani Y, Schilhabel M, Karygianni L, Hellwig E, Rehman A: Comparison of the bacterial composition and structure in symptomatic and asymptomatic endodontic infections associated with root-filled teeth using pyrosequencing. Plos One, 2013; 8 (12) (online): e84960. : http://dx.doi.org/10.1371/journal.pone.0084960
  • Hannig C, Basche S, Burghardt T, Al-Ahmad A, Hannig M: Influence of a mouthwash containing hydroxyapatite microclusters on bacterial adherence in situ. Clin Oral Invest, 2013; 17 (3): 805-814. : http://dx.doi.org/10.1007/s00784-012-0781-6
  • Hannig C, Kirsch J, Al-Ahmad A, Kensche A, Hannig M, Kümmerer K: Do edible oils reduce bacterial colonization of enamel in situ? Clin Oral Invest, 2013; 17 (2): 649-658.
  • Karygianni L, Jähnig A, Schienle S, Bernsmann F, Adolfsson E, Kohal R, Chevalier J, Hellwig E, Al-Ahmad A: Initial Bacterial Adhesion on Different Yttria-Stabilized Tetragonal Zirconia Implant Surfaces in Vitro Materials, 2013; 6: 5659-5674.
  • Reich M, Kummerer K, Al-Ahmad A, Hannig C: Fatty Acid profile of the initial oral biofilm (pellicle): an in-situ study. Lipids, 2013; 48 (9): 929-937. : http://dx.doi.org/10.1007/s11745-013-3822-2
  • Sauerbier S, Gutwald R, Wiedmann-Al-Ahmad M, Wolkewitz M, Haberstroh J, Obermeyer J, Kuenz A, Betz H, Wolter F, Duttenhofer F, Schmelzeisen R, Nagursky H, Proksch S, Al-Ahmad A: Effect of gabapentin-lactam and gamma-aminobutyric acid/lactam analogs on proliferation and phenotype of ovine mesenchymal stem cells. Int J Oral Max Impl, 2013; 28 (5) (online): e230-e238. : http://dx.doi.org/10.11607/jomi.te02
  • Tawakoli PN, Al-Ahmad A, Hoth-Hannig W, Hannig M, Hannig C: Comparison of different live/dead stainings for detection and quantification of adherent microorganisms in the initial oral biofilm. Clin Oral Invest, 2013; 17 (3): 841-850. : http://dx.doi.org/10.1007/s00784-012-0792-3
  • Al-Ahmad A, Kurschner A, Weckesser S, Wittmer A, Rauberger H, Jakob T, Hellwig E, Kist M, Waidner B: Is Helicobacter pylori resident or transient in the human oral cavity? J Med Microbiol, 2012; 61 (Pt 8): 1146-1152. : http://dx.doi.org/10.1099/jmm.0.043893-0
  • Anderson AC, Hellwig E, Vespermann R, Wittmer A, Schmid M, Karygianni L, Al-Ahmad A: Comprehensive analysis of secondary dental root canal infections: a combination of culture and culture-independent approaches reveals new insights. Plos One, 2012; 7 (11) (online): e49576. : http://dx.doi.org/10.1371/journal.pone.0049576
  • Karygianni L, Follo M, Hellwig E, Burghardt D, Wolkewitz M, Anderson A, Al-Ahmad A: Microscope-based imaging platform for large-scale analysis of oral biofilms. Appl Environ Microb, 2012; 78 (24): 8703-8711. : http://dx.doi.org/10.1128/AEM.02416-12
  • Karygianni L, Wiedmann-Al-Ahmad M, Finkenzeller G, Sauerbier S, Wolkewitz M, Hellwig E, Al-Ahmad A: Enterococcus faecalis affects the proliferation and differentiation of ovine osteoblast-like cells. Clin Oral Invest, 2012; 16 (3): 879-887. : http://dx.doi.org/10.1007/s00784-011-0563-6
  • Kimmerle H, Wiedmann-Al-Ahmad M, Pelz K, Wittmer A, Hellwig E, Al-Ahmad A: Airborne microbes in different dental environments in comparison to a public area. Arch Oral Biol, 2012; 57 (6): 689-696. : http://dx.doi.org/10.1016/j.archoralbio.2011.11.012
  • Proksch S, Steinberg T, Keller C, Wolkewitz M, Wiedmann-Al-Ahmad M, Finkenzeller G, Hannig C, Hellwig E, Al-Ahmad A: Human saliva exposure modulates bone cell performance in vitro. Clin Oral Invest, 2012; 16 (1): 69-77. : http://dx.doi.org/10.1007/s00784-010-0506-7
  • Redondo AH, Korber C, Konig S, Langin A, Al-Ahmad A, Weinmann W: Inhibition of bacterial degradation of EtG by collection as dried urine spots (DUS). Anal Bioanal Chem, 2012; 402 (7): 2417-2424. : http://dx.doi.org/10.1007/s00216-011-5687-7
  • Reich M, Hannig C, Al-Ahmad A, Bolek R, Kummerer K: A comprehensive method for determination of fatty acids in the initial oral biofilm (pellicle). J Lipid Res, 2012; 53 (10): 2226-2230. : http://dx.doi.org/10.1194/jlr.D026260
  • Al-Ahmad A, Schubert C, Carvalho C, Thoman Y, Wittmer A, Metzger M, Hellwig E, Swieszkowski W, Wiedmann-Al-Ahmad M: Comparison of bacterial adhesion and cellular proliferation on newly developed three-dimensional scaffolds manufactured by rapid prototyping technology. J Biomed Mater Res A, 2011; 98 (2): 303-311. : http://dx.doi.org/10.1002/jbm.a.33118
  • Sauerbier S, Gutwald R, Wiedmann-Al-Ahmad M, Wolkewitz M, Haberstroh J, Obermeyer J, Kuenz A, Betz H, Wolter F, Duttenhöfer F, Schmelzeisen R, Nagursky H, Proksch S, Al-Ahmad A: Effect of Gabapentin-Lactam and Gamma-Aminobutyric Acid/Lactam Analogs on Proliferation and Phenotype of Ovine Mesenchymal Stem Cells Oral & Craniofacial Tissue Engineering, 2011; 1 (1): 20-28.
  • Senges C, Wrbas KT, Altenburger M, Follo M, Spitzmuller B, Wittmer A, Hellwig E, Al-Ahmad A: Bacterial and Candida albicans adhesion on different root canal filling materials and sealers. J Endodont, 2011; 37 (9): 1247-1252. : http://dx.doi.org/10.1016/j.joen.2011.05.034
  • Al-Ahmad A, Maier J, Follo M, Spitzmuller B, Wittmer A, Hellwig E, Hubner J, Jonas D: Food-borne enterococci integrate into oral biofilm: an in vivo study. J Endodont, 2010; 36 (11): 1812-1819. : http://dx.doi.org/10.1016/j.joen.2010.08.011
  • Al-Ahmad A, Roth D, Wolkewitz M, Wiedmann-Al-Ahmad M, Follo M, Ratka-Kruger P, Deimling D, Hellwig E, Hannig C: Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm. Clin Oral Invest, 2010; 14 (4): 391-396. : http://dx.doi.org/10.1007/s00784-009-0318-9
  • Al-Ahmad A, Wiedmann-Al-Ahmad M, Deimling D, Jaser C, Pelz K, Wittmer A, Ratka-Krüger P: An antimicrobial effect from silver-coated toothbrush heads Am J Dent, 2010; 23: 251-254.
  • Al-Ahmad A, Wiedmann-Al-Ahmad M, Faust J, Bachle M, Follo M, Wolkewitz M, Hannig C, Hellwig E, Carvalho C, Kohal R: Biofilm formation and composition on different implant materials in vivo. J Biomed Mater Res B, 2010; 95 (1): 101-109. : http://dx.doi.org/10.1002/jbm.b.31688
  • Hannig C, Spitzmuller B, Lux HC, Altenburger M, Al-Ahmad A, Hannig M: Efficacy of enzymatic toothpastes for immobilisation of protective enzymes in the in situ pellicle. Arch Oral Biol, 2010; 55 (7): 463-469. : http://dx.doi.org/10.1016/j.archoralbio.2010.03.020
  • Jung DJ, Al-Ahmad A, Follo M, Spitzmüller B, Hoth-Hannig W, Hannig M, Hannig C: Visualization of initial bacterial colonization on dentine and enamel in situ J Microbiol Meth, 2010; 81 (2): 166-174. : http://dx.doi.org/10.1016/j.mimet.2010.03.002
  • Kümmerer K, Al-Ahmad A: Estimation of the cancer risk to humans resulting from the presence of cyclophosphamide and ifosfamide in surface water. Environ Sci Pollut R, 2010; 17 (2): 486-496. : http://dx.doi.org/10.1007/s11356-009-0195-4
  • Al-Ahmad A, Follo M, Selzer AC, Hellwig E, Hannig M, Hannig C: Bacterial colonization of enamel in situ investigated using fluorescence in situ hybridization. J Med Microbiol, 2009; 58 (Pt 10): 1359-1366. : http://dx.doi.org/10.1099/jmm.0.011213-0
  • Al-Ahmad A, Haiss A, Unger J, Brunswick-Tietze A, Wiethan J, Kummerer K: Effects of a realistic mixture of antibiotics on resistant and nonresistant sewage sludge bacteria in laboratory-scale treatment plants. Arch Environ Con Tox, 2009; 57 (2): 264-273. : http://dx.doi.org/10.1007/s00244-008-9259-6
  • Al-Ahmad A, Muller N, Wiedmann-Al-Ahmad M, Sava I, Hubner J, Follo M, Schirrmeister J, Hellwig E: Endodontic and salivary isolates of Enterococcus faecalis integrate into biofilm from human salivary bacteria cultivated in vitro. J Endodont, 2009; 35 (7): 986-991. : http://dx.doi.org/10.1016/j.joen.2009.04.013
  • Halter CC, Laengin A, Al-Ahmad A, Wurst FM, Weinmann W, Kuemmerer K: Assessment of the stability of the ethanol metabolite ethyl sulfate in standardised degradation tests. Forensic Sci Int, 2009; 186 (1-3): 52-55. : http://dx.doi.org/10.1016/j.forsciint.2009.01.009
  • Hannig C, Sorg J, Spitzmuller B, Hannig M, Al-Ahmad A: Polyphenolic beverages reduce initial bacterial adherence to enamel in situ. J Dent, 2009; 37 (7): 560-566. : http://dx.doi.org/10.1016/j.jdent.2009.03.017
  • Sauerbier S, Palmowski M, Vogeler M, Nagursky H, Al-Ahmad A, Fisch D, Hennig J, Schmelzeisen R, Gutwald R, Fasol U: Onset and maintenance of angiogenesis in biomaterials: in vivo assessment by dynamic contrast-enhanced MRI. Tissue Eng Part C Methods, 2009; 15 (3): 455-462. : http://dx.doi.org/10.1089/ten.tec.2008.0626
  • Schirrmeister JF, Liebenow AL, Pelz K, Wittmer A, Serr A, Hellwig E, Al-Ahmad A: New bacterial compositions in root-filled teeth with periradicular lesions. J Endodont, 2009; 35 (2): 169-174. : http://dx.doi.org/10.1016/j.joen.2008.10.024
  • Al-Ahmad A, Pelz K, Schirrmeister JF, Hellwig E, Pukall R: Characterization of the first oral vagococcus isolate from a root-filled tooth with periradicular lesions. Curr Microbiol, 2008; 57 (3): 235-238.
  • Al-Ahmad A, Wiedmann-Al-Ahmad M, Auschill TM, Follo M, Braun G, Hellwig E, Arweiler NB: Effects of commonly used food preservatives on biofilm formation of Streptococcus mutans in vitro. Arch Oral Biol, 2008; 53 (8): 765-772.
  • Al-Ahmad A, Wiedmann-Al-Ahmad M, Carvalho C, Lang M, Follo M, Braun G, Wittmer A, Mulhaupt R, Hellwig E: Bacterial and Candida albicans adhesion on rapid prototyping-produced 3D-scaffolds manufactured as bone replacement materials. J Biomed Mater Res A, 2008; 87 (4): 933-943.
  • Arweiler NB, Lenz R, Sculean A, Al-Ahmad A, Hellwig E, Auschill TM: Effect of food preservatives on in situ biofilm formation. Clin Oral Invest, 2008; 12 (3): 203-208.
  • Hannig C, Spitzmuller B, Al-Ahmad A, Hannig M: Effects of Cistus-tea on bacterial colonization and enzyme activities of the in situ pellicle. J Dent, 2008; 36 (7): 540-545.
  • Schmitt SC, Wiedmann-Al-Ahmad M, Kuschnierz J, Al-Ahmad A, Huebner U, Schmelzeisen R, Gutwald R: Comparative in vitro study of the proliferation and growth of ovine osteoblast-like cells on various alloplastic biomaterials manufactured for augmentation and reconstruction of tissue or bone defects. J Mater Sci-mater M, 2008; 19 (3): 1441-1450.
  • Thierauf A, Serr A, Halter CC, Al-Ahmad A, Rana S, Weinmann W: Influence of preservatives on the stability of ethyl glucuronide and ethyl sulphate in urine. Forensic Sci Int, 2008; 182 (1-3): 41-45. : http://dx.doi.org/10.1016/j.forsciint.2008.09.011
  • Al-Ahmad A, Wunder A, Auschill TM, Follo M, Braun G, Hellwig E, Arweiler NB: The in vivo dynamics of Streptococcus spp., Actinomyces naeslundii, Fusobacterium nucleatum and Veillonella spp. in dental plaque biofilm as analysed by five-colour multiplex fluorescence in situ hybridization. J Med Microbiol, 2007; 56 (Pt 5): 681-687.
  • Hannig C, Hannig M, Rehmer O, Braun G, Hellwig E, Al-Ahmad A: Fluorescence microscopic visualization and quantification of initial bacterial colonization on enamel in situ. Arch Oral Biol, 2007; 52 (11): 1048-1056.
  • Itthichaisri C, Wiedmann-Al-Ahmad M, Huebner U, Al-Ahmad A, Schoen R, Schmelzeisen R, Gellrich NC: Comparative in vitro study of the proliferation and growth of human osteoblast-like cells on various biomaterials. J Biomed Mater Res A, 2007; 82 (4): 777-787.
  • Schirrmeister JF, Liebenow AL, Braun G, Wittmer A, Hellwig E, Al-Ahmad A: Detection and Eradication of Microorganisms in Root-filled Teeth Associated With Periradicular Lesions: An In Vivo Study. J Endodont, 2007; 33 (5): 536-540.
  • Wagner M, Kiapur N, Wiedmann-Al-Ahmad M, Hubner U, Al-Ahmad A, Schon R, Schmelzeisen R, Mulhaupt R, Gellrich NC: Comparative in vitro study of the cell proliferation of ovine and human osteoblast-like cells on conventionally and rapid prototyping produced scaffolds tailored for application as potential bone replacement material. J Biomed Mater Res A, 2007; 83 (4): 1154-1164.
  • Al-Ahmad A, Auschill TM, Braun G, Hellwig E, Arweiler NB: Overestimation of Streptococcus mutans prevalence by nested PCR detection of the 16S rRNA gene. J Med Microbiol, 2006; 55: 109-113.
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
Buchbeiträge:
  • Al-Ahmad A, Wiedmann Al-Ahmad M, Carvalho C, Hellwig E: Bacterial and Candida albicans Adhesion of Rapid Prototyping-Produced 3D-Scaffolds Manufactured as Bone Replacement Materials In: Computer Aided Biomanufacturing Weinheim: Wiley-VCH, 2011; 54-71.
Kurzbeiträge / short communications:
  • Al-Ahmad A, Hellwig E, Wittmer A, Kist M, Waidner B: Re: the impact of the stone age diet on gingival conditions in the absence of oral hygiene. Baumgartner S, Imfeld T, Schicht O, Rath C, Persson RE, Persson GR. (J Periodontol 2009;80:759-768.). J Periodontol, 2010; 81 (3): 338; author reply 338-338; author reply 339. : http://dx.doi.org/10.1902/jop.2010.090546
Vorträge:
  • Al-Ahmad A, Schirrmeister J, Wittmer A, Liebenow A, Hellwig E: Neue Bakterienkombinationen in wurzelkanalbehandelten Zähnen mit periradikulären Läsionen. 2009 (41. Jahrestagung der AfG (Arbeitsgemeinschaft für Grundlagenforschung der DGZMK), 08.01.- 09.01.2009, Mainz).
  • Al-Ahmad A, Lang M, Wiedmann-al-Ahmad M, Carvalho C, Hellwig E: Mikrobielle Adhäsion an drei unterschiedlichen 3D-Scaffolds. 2007 (39. Jahrestagung der Arbeitsgemeinschaft für Grundlagenforschung der Deutschen Gesellschaft für Mund- und Kieferheilkunde (DGZMK). 11.01. - 12.01.2007, Mainz).
  • Al-Ahmad A, Liebenow A, Wittmer A, Pelz K, Hellwig E, Schirrmeister JF: Prevalence and diversity of bacteria in root-filled teeth associated with periradicular lesions. 2007 (17th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) and 25th International Congress of Chemotherapy (ICC). 31.03. - 03.04.2007, München).
  • Arweiler NB, Wunder A, Braun G, Al-Ahmad A: Die bakterielle Kolonisation des dentalen Biofilms über 7 Tage mittels Multiplex-FISH-Analyse. 2007 (39. Jahrestagung der Arbeitsgemeinschaft für Grundlagenforschung der Deutschen Gesellschaft für Mund- und Kieferheilkunde (DGZMK). 11.01. - 12.01.2007, Mainz).
  • Beier DP, Auschill TM, Al-Ahmad A, Hellwig E, Arweiler NB: Der Einfluss von Konservierungsmitteln auf die Demineralisationswirkung dentaler in situ Biofilm. 2007 (Deutscher Zahnärztetag, 131. Jahrestagung der DGZMK, 22.11. - 24.11.2007, Düsseldorf).
  • Grunert SD, Auschill TM, Al-Ahmad A, Hellwig E, Arweiler NB: Der Einfluss von Nahrungskonservierungsmitteln auf die dentale, in situ Biofilmbildung. 2007 (Deutscher Zahnärztetag, 131. Jahrestagung der DGZMK, 22.11. - 24.11.2007, Düsseldorf).
  • Hannig C, Al-Ahmad A, Roth D, Ratka-Krüger P, Deimling D, Hellwig E: Das Steinzeitprojekt – ein anthropologisches Experiment aus zahnärztlicher Sicht. 2007 (Deutscher Zahnärztetag, 131. Jahrestagung der DGZMK, 22.11. - 24.11.2007, Düsseldorf).
  • Hannig C, Rehmer O, Hellwig E, HannigM, Al-Ahmad A: Detektion von Mikroorganismen in der In-situ-Pellikel - ein Methodenvergleich. 2007 (39. Jahrestagung der Arbeitsgemeinschaft für Grundlagenforschung der Deutschen Gesellschaft für Mund- und Kieferheilkunde (DGZMK). 11.01. - 12.01.2007, Mainz).
  • Schirrmeister JF, Liebenow AL, Braun G, Wittmer A, Hellwig E, Al-Ahmad A: Evaluation eines Desinfektionsprotokolls bei der Revision von Wurzelkanalfüllungen in vivo. 2006 (5. Jahrestagung der Deutschen Gesellschaft für Endodontie, 02.11.-04.11.2006, Dresden).
Konferenzbeiträge:
  • Al-Ahmad A, Faust J, Bächle M, Follo M, Hellwig E, Carvalho C, Kohal R: Biofilm formation and composition on different implant materials in situ. 2010 (IADR General Session,14.07.-17.07.2010, Barcelona, Spanien).
  • Al-Ahmad A, Maier J, Spitzmüller B, Hellwig E, Jonas D: /Enterococcus faecalis/ aus Lebensmitteln im reifen supragingivalen Plaque-Biofilm. 2010 (42. Jahrestagung der Arbeitsgemeinschaft für Grundlagenforschung der Deutschen Gesellschaft für Mund- und Kieferheilkunde (DGZMK). 07.01.-08.01.2010, Mainz.).
  • Al-Ahmad A, Spitzmüller B, Maier J, Wittmer A, Follo M, Hellwig E, Jonas D: Food born enterococci in oral biofilm: an in vivo human study. 2010 (European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10.04.-13.04.2010, Wien., Österreich).
  • Altenburger MJ, Ganter P, Hellwig E, Wrbas KT, Al-Ahmad A: The Use of Computer-Assisted Light Fluorescence. Caries Res, 2010; 44: 171-247 (ORCA Meeting, 07.07.-10.07.2010, Montpellier, Frankreich), Karger (Hrsg).
  • Karygianni L, Wiedmann-Al-Ahmad M, Braun G, Finkenzeller G, Proksch S, Sauerbier S, Hellwig E, Al-Ahmad A: E. faecalis affects proliferation and differentiation of ovine-osteoblast cells. J Dent Res, 2010 (89) Suppl. B (IADR General Session,14.07.-17.07.2010, Barcelona, Spanien), Sage (Hrsg). : http://iadr.confex.com/iadr/2010barce/webprogram/Paper134414.html
  • Proksch S, Steinberg T, Keller C, Wolkewitz M, Wiedmann-Al-Ahmad, Finkenzeller G, Hannig C, Hellwig E, Al-Ahmad A: Human saliva harms osteoblast-like cells in vitro. J Dent Res, 2010 (89) Suppl. B (IADR General Session,14.07.-17.07.2010, Barcelona, Spanien), Sage (Hrsg). : http://iadr.confex.com/iadr/2010barce/webprogram/Paper136724.html
  • Abouassi T, Wolkewitz M, Al-Ahmad A, Hahn P: Effect of Different Bleaching Gels on Enamel Surface. 2009 (87th IADR/AADR/CADR General Meeting, 01.04. -04.04.2009, Miami, USA).
  • Al-Ahmad A, Faust J, Follo M, Bächle M, Hellwig E, Kohal RJ: In vivo biofilm formation on different oral implant biomaterials. 2009 (FEMS (Federation of European Microbiological Societies) 2009: The 3rd Congress of European Microbiologists, 28.06.-02.07.2009, Gothenburg, Sweden).
  • Hannig C, Follo M, Selzer AC, Hellwig E, Hannig M, Al-Ahmad A: Bacterial colonization of enamel in situ investigated with fluorescence in situ hybridization (FISH). 2009 (44th meeting of the IADR-Continental European Division (CED) together with the Scandinavian Division and Israeli Division, 09.09.-12.09.2009, München).
  • Hannig C, Sorg J, Spitzmüller B, Hellwig E, Hannig M, Al-Ahmad A: Der Einfluss polyphenolhaltiger Getränke auf die initiale bakterielle Kolonisation – eine In-situ-Studie. Autoreferateband, 2009; Suppl. #6: 35 (23. Jahrestagung der Deutschen Gesellschaft für Zahnerhaltung e. V., 15.05.-16.05.2009, Hannover).
  • Al-Ahmad A, Fackler A, Bächle M, Han J-S, Hellwig E, Kohal RJ: Initial Bacterial Adhesion on six different oral implant materials in situ. 2008 (Biofilms III: 3rd International Conference. 06.10.-08.10.2008, München).
  • Al-Ahmad A, Müller N, Hübner J, Follo M, Hellwig E: Klinische Isolate von E. faecalis können sich in einem in vitro Biofilm aus Speichelbakterien integrieren. 2008 (40. Jahrestagung der Arbeitsgemeinschaft für Grundlagenforschung, 10.01.-11.01.2008, Mainz).
  • Faust J, Kohal RJ, Follo M, Bächle M, Wolkewitz M, Braun G, Hellwig E, Al-Ahmad A: Molekulargenetische Untersuchung der mikrobiologischen Biofilmzusammensetzung an verschiedenen Implantatmaterialien in situ. DZZ (Deutsche Zahnärzte Zeitschrift), 2008; 63 (10) (63. DGZMK-Jahrestagung/Deutscher Zahnärztetag, 22.10.-25.10.2008, Stuttgart, Oktober/2008).
  • Schirrmeister JF, Liebenow AL, Wittmer A, Pelz K, Hellwig E, Al-Ahmad A: Prevalence and elimination of microorganisms in root filled teeth associated with periradicular lesions. Int Endod J, 2007; 40 (12): 987 (13th biennial congress of the European Society of Endodontology. 06.09.-08.09.2007, Istanbul, Türkei), ESE (Hrsg).
  • Auschill TM, Lenz R, Hellwig E, Al-Ahmad A, Arweiler NB: Der Einfluss von Konservierungsstoffen auf den intraoralen Biofilm. Autoreferate-Band zur 20. Jahrestagung der DGZ, 2006: 63 (20. Jahrestagung der DGZ, 11.05.-13.05. 2006, Mainz).
  • Al-Ahmad A, Auschill TM, Hellwig E, Arweiler NB: Einfluss von Nahrungsmittel-Konservierungsstoffen auf die Lebendkeimzahl von Biofilmbakterien. Deutsche Zahnärztliche Zeitschrift, 2005; Sonderheft Suppl. 2005: #253 (Zahn-Medizin Interdisziplinär, 26.10.-30.10.2005, Berlin).
  • Al-Ahmad A, Auschill TM, Kobberstad SK, Braun G, Sendic M, Hellwig E, Arweiler NB: Effects of food preservatives on oral streptococci biofilm generated in a biofilm reactor. Clin Microbiol Infec, 2005; 11 Suppl. 2: 544 (15th ECCMID (European Congress of Clinical Microbiology and Infectious Diseases), 02.04.-05.04.2005, Copenhagen, Denmark), European Society of Clinical Microbiology and Infectious Diseases (Hrsg).
  • Kobberstad SK, Auschill TM, Al-Ahmad A, Hellwig E, Arweiler NB: Der Einfluss von Nahrungs-Konservierungsmitteln auf die Dicke und Vitalität laborbasierter Biofilme. Deutsche Zahnärztliche Zeitschrift, 2005: #254 (Zahn-Medizin Interdisziplinär, 26.10.-30.10.2005, Berlin).
  • Al-Ahmad A, Auschill T, Kobberstad S, Sendic M, Deimling D, Hellwig E, Arweiler NB: The Influence of chlorhexidine on biofilm generated with oral streptococci in an artificial mouth. Int J Med Microbiol, 2004; 294S1 Suppl. 39: 190 (56. Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie. 26.09.-29.09.2004, Münster).