Research Report for the year 2019

Scientific publications

Journal Articles:
  • Akhtar J, Kreim N, Marini F, Mohana G, Brüne D, Binder H, Roignant JY: Promoter-proximal pausing mediated by the exon junction complex regulates splicing. Nat Commun, 2019; 10 (online): 521. : https://doi.org/10.1038/s41467-019-08381-0
  • Chaabane S, Harfouche M, Chemaitelly H, Schwarzer G, Abu-Raddad LJ: Herpes simplex virus type 1 epidemiology in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions. Sci Rep-uk, 2019; 9 (online): 1136. : https://doi.org/10.1038/s41598-018-37833-8
  • Clemens E, Meijer AJ, Broer L, Langer T, van der Kooi AL, Uitterlinden AG, de Vries A, Kuehni CE, Garrè ML, Kepak T, Kruseova J, Winther JF, Kremer LC, van Dulmen-den Broeder E, Tissing WJ, Rechnitzer C, Kenborg L, Hasle H, Grabow D, Parfitt R, Binder H, Carleton BC, Byrne J, Kaatsch P, Am Zehnhoff-Dinnesen A, Zolk O, van den Heuvel-Eibrink MM: Genetic Determinants of Ototoxicity During and After Childhood Cancer Treatment: Protocol for the PanCareLIFE Study. JMIR research protocols, 2019; 8 (online): e11868. : https://doi.org/10.2196/11868
  • El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schurmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Kruger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Muller AH, Ulzen A, Bader P, Bakhtiar S, Lee JY, Hess U, Schubert R, Wolke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Honig M, Schulz A, Steinmann S, Schwarz K, Duckers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Muglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Muller C, Rosen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hulsmann B, Schonberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Muller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Gross-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Munstermann E, Schneider DT, Tietsch N, Westkemper M, Weiss M, Kramm C, Kuhnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Muller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B: The German National Registry of Primary Immunodeficiencies (2012-2017). Front Immunol, 2019; 10 (online): 1272-1272. : http://dx.doi.org/10.3389/fimmu.2019.01272
  • Geschke K, Weyer-Elberich V2, Mueller AK, Binder H, Fellgiebel A: Feasibility and utility of a cognitive screening for risk stratification in hospitalized older patients. Int J Geriatr Psych, 2019; 34: 588-593. : https://doi.org/10.1002/gps.5056
  • Graetz C, Gröger A, Luessi F, Salmen A, Zöller D, Schultz J, Siller N, Fleischer V, Bellenberg B, Berthele A, Biberacher V, Havla J, Hecker M, Hohlfeld R, Infante-Duarte C, Kirschke JS, Kümpfel T, Linker R, Paul F, Pfeuffer S, Sämann P, Toenges G, Weber F, Zettl UK, Jahn-Eimermacher A, Antony G, Groppa S, Wiendl H, Hemmer B, Mühlau M, Lukas C, Gold R, Lill CM, Zipp F: Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis. Mult Scler J, 2019; 25: 661-668. : https://doi.org/10.1177/1352458518763541
  • Hasselblatt H, Andrae J, Tassoni A, Fitzer K, Bahls T, Prokosch HU, Boeker M: Establishing an Interoperable Clinical Trial Information System Within MIRACUM. Stud Health Technol Inform, 2019; 258: 216-220.
  • Heister T, Wolkewitz M, Hehn P, Wolff J, Dettenkofer M, Grundmann H, Kaier K: Costs of hospital-acquired Clostridium difficile infections: an analysis on the effect of time-dependent exposures using routine and surveillance data. Cost Effectiveness and Resource Allocation, 2019; 17: 16. : https://doi.org/10.1186/s12962-019-0184-5
  • Hempler I, Maun A, Kampling H, Thielhorn U, Farin E: Schlaganfallnachsorge in Deutschland : Ergebnisse einer Online-Befragung stationär und ambulant tätiger Experten in Süddeutschland Nervenarzt, 2019; 8: 824-831. : https://doi.org/10.1007/s00115-018-0655-5
  • Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Hädicke J, Löning T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann MW, Gebhardt M, Friedrich M, Münstedt K, Schneider A, Kaufmann A, Petry KU, Schäfer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M: Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 1 with Introduction, Screening and the Pathology of Cervical Dysplasia. Geburtsh Frauenheilk, 2019; 79: 148-159. : https://doi.org/10.1055/a-0818-5440
  • Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Hädicke J, Löning T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann MW, Gebhardt M, Friedrich M, Münstedt K, Schneider A, Kaufmann A, Petry KU, Schäfer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M: Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 2 on Triage, Treatment and Follow-up. Geburtsh Frauenheilk, 2019; 79: 160-176. : https://doi.org/10.1055/a-0828-7722
  • Jabbarli R, Pierscianek D, Rölz R, Darkwah Oppong M, Kaier K, Shah M, Taschner C, Mönninghoff C, Urbach H, Beck J, Sure U, Forsting M: Endovascular treatment of cerebral vasospasm after subarachnoid hemorrhage: More is more. Neurology, 2019; 93 (online): e1-e9. : https://doi.org/10.1212/WNL.0000000000007862
  • Kalisch R, Cramer AOJ, Binder H, Fritz J, Leertouwer I, Lunansky G, Meyer B, Timmer J, Veer IM, van Harmelen AL: Deconstructing and Reconstructing Resilience: A Dynamic Network Approach. Perspect Psychol Sci, 2019; 14: 765-777. : https://doi.org/10.1177/1745691619855637
  • Kampling H, Brendel L, Mittag O: (Neuro)Psychological Interventions for Non-Motor Symptoms in the Treatment of Patients with Parkinson’s Disease: a Systematic Umbrella Review Neuropsychol Rev, 2019; 29 (2): 166-180. : https://doi.org/10.1007/s11065-019-09409-4
  • Kampling H, Küst J, Allert N, Dettmers C, Mittag O: Praxisempfehlungen für psychologische Interventionen in der neurologischen Rehabilitation: Multiple Sklerose, Idiopathisches Parkinson-Syndrom & Schlaganfall Z Neuropsychol, 2019; 30 (1): 45-47. : http://doi.org/10.1024/1016-264X/a000248
  • Khadr L, Harfouche M, Omori R, Schwarzer G, Chemaitelly H, Abu-Raddad LJ: The Epidemiology of Herpes Simplex Virus Type 1 in Asia: Systematic Review, Meta-analyses, and Meta-regressions. Clin Infect Dis, 2019; 68: 757-772. : https://doi.org/10.1093/cid/ciy562
  • Marini F, Binder H: pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components. Bmc Bioinformatics, 2019; 20 (online): 331. : https://doi.org/10.1186/s12859-019-2879-1
  • Merz J, Schwarzer G, Gerger H: Comparative Efficacy and Acceptability of Pharmacological, Psychotherapeutic, and Combination Treatments in Adults With Posttraumatic Stress Disorder: A Network Meta-analysis. Jama Psychiat, 2019; 76: 904-913. : https://doi.org/10.1001/jamapsychiatry.2019.0951
  • Ponto KA, Scharrer I, Binder H, Korb C, Rosner AK, Ehlers TO, Rieser N, Grübel NC, Rossmann H, Wild PS, Feltgen N, Pfeiffer N, Mirshahi A: Hypertension and multiple cardiovascular risk factors increase the risk for retinal vein occlusions: results from the Gutenberg Retinal Vein Occlusion Study. J Hypertens, 2019; 37: 1372-1383. : https://doi.org/10.1097/HJH.0000000000002057
  • Prasse A, Binder H, Schupp JC, Kayser G, Bargagli E, Jaeger B, Hess M, Rittinghausen S, Vuga L, Lynn H, Violette S, Jung B, Quast K, Vanaudenaerde B, Xu Y, Hohlfeld JM, Krug N, Herazo-Maya JD, Rottoli P, Wuyts WA, Kaminski N: BAL Cell Gene Expression is Indicative of Outcome and Airway Basal Cell Involvement in IPF. Am J Resp Crit Care, 2019; 199: 622-630. : https://doi.org/10.1164/rccm.201712-2551OC
  • Rieg S, von Cube M, Kaasch A, Bonaventura B, Bothe W, Wolkewitz M, Peyerl-Hoffmann G, Deppe AC, Wahlers T, Beyersdorf F, Seifert H, Kern WV: Investigating the impact of early valve surgery on survival in Staphylococcus aureus infective endocarditis using a marginal structural model approach - results of a large prospectively evaluated cohort. Clin Infect Dis, 2019; 69: 487-494. : https://doi.org/10.1093/cid/ciy908
  • Schaaf J, Boeker M, Ganslandt T, Haverkamp C, Hermann T, Kadioglu D, Prokosch HU, Wagner TOF, von Wagner M, Schaefer J, Sedlmayr M, Storf H: Finding the Needle in the Hay Stack: An Open Architecture to Support Diagnosis of Undiagnosed Patients. Stud Health Technol Inform, 2019; 264: 1580-1581. : http://dx.doi.org/10.3233/SHTI190544
  • Schmidtmann I, Konstantinides S, Binder H: Power of the Wilcoxon–Mann–Whitney test for non‐inferiority in the presence of death‐censored observations. Biometrical J, 2019; 61: 1187-1200. : https://doi.org/10.1002/bimj.201700296
  • Schulz J, Takousis P, Wohlers I, Itua IOG, Dobricic V, Rücker G, Binder H, Middleton L, Ioannidis JPA, Perneczky R, Bertram L, Lill CM: Meta-analyses identify differentially expressed microRNAs in Parkinson's disease. Ann Neurol, 2019; 85: 835-851. : https://doi.org/10.1002/ana.25490
  • Schwarzer G, Chemaitelly H, Abu-Raddad LJ, Rücker G: Seriously misleading results using inverse of Freeman‐Tukey double arcsine transformation in meta‐analysis of single proportions. Res Synth Methods, 2019; 10: 476-483. : https://doi.org/10.1002/jrsm.1348
  • Sprinzl MF, Kirstein MM, Koch S, Seib M-L, Weinmann-Menke J, Lang H, Düber C, Toenges G, Zöller D, Marquardt JU, Wörns M-A, Galle PR, Vogel A, Pinter M, Weinmann A: Improved Prediction of Survival by a Risk Factor-Integrating Inflammatory Score in Sorafenib-Treated Hepatocellular Carcinoma. Liver Cancer, 2019 (online). : http://dx.doi.org/10.1159/000492628
  • Stelzer A-S, Maccioni L, Gerhold-Ay A, Smedby KE, Schumacher M, Nieters A, Binder H: A multivariable approach for riskmarkers from pooled molecular data withonly partial overlap. Bmc Med Genet, 2019; 20 (online): 128. : https://doi.org/10.1186/s12881-019-0849-0
  • Tibubos AN, Ernst M, Brähler E, Fischbeck S, Hinz A, Blettner M, Zeissig SR, Weyer V, Imruck BH, Binder H, Beutel ME: Fatigue in survivors of malignant melanoma and its determinants: a register-based cohort study. Support Care Cancer, 2019; 27: 2809-2818. : https://doi.org/10.1007/s00520-018-4587-1
  • Toews I, Lohner S, Küllenberg de Gaudry D, Sommer H, Meerpohl JJ: Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies. Bmj-brit Med J, 2019; 364 (online): k4718 . : https://doi.org/10.1136/bmj.k4718
Book Chapters:
  • Schlöffel M, Kampling H, Pollmann H, Mittag O: Der Online-Rehabedarfstest (OREST): Neue Wege in die medizinische Rehabilitation In: Pfannstiel M A; Da-Cruz P; Mehlich H (Hrsg.): Digitale Transformation von Dienstleistungen im Gesundheitswesen V, 1. Auflage. Berlin: Springer, 2019; 101-127.
Short Communications:
  • Khadr L, Harfouche M, Omori R, Schwarzer G, Chemaitelly H, Abu-Raddad LJ: Reply to Brijwal et al. Clin Infect Dis, 2019; 68: 1784. : http://10.1093/cid/ciy944
Conference Papers:
  • Farin-Glattacker E, Binder H, Wangler J, Jansky M, Löhr M, Schulz M, Krämer I, Mildner C, Wuttke-Linnemann A, Fellgiebel A: Hausarztbasierte Demenzversorgung mit koordinierter Kooperation und Einsatz spezialisierter Pflegekräfte (DemStepCare): Studienübersicht und Evaluationskonzept 18. Deutscher Kongress für Versorgungsforschung (DKVF), 2019 (Deutscher Kongress für Versorgungsforschung/Berlin/Deutsches Netzwerk Versorgugsforschung e.V.), German Medical Science GMS Publishing House; Düsseldorf (Hrsg).
  • Zabka S, Ammon D, Ganslandt T, Gewehr J, Haverkamp C, Kiefer S, Lautenbacher H, Löbe M, Thun S, Boeker M: Towards a Medication Core Data Set for the Medical Informatics Initiative (MII): Initial Mapping Experience between the German Procedure Classification (OPS) and the Identification of Medicinal Products (IDMP). Proceedings of the Joint Ontology Workshops, 2019; 2518 (Joint Ontology Workshop, Episode V: The Styrian Autumn of Ontology, Graz, Austria, September 23-25, 2019), Adrien Barton, Selja Seppälä, Daniele Porello (Hrsg). (download: http://ceur-ws.org/Vol-2518/paper-ODLS14.pdf)