Research Report for the year 2018

Scientific publications

Journal Articles:
  • Bluhmki T, Allignol A, Ruckly S, Timsit JF, Wolkewitz M, Beyersmann J: Estimation of adjusted expected excess length-of-stay associated with ventilation-acquired pneumonia in intensive care: A multistate approach accounting for time-dependent mechanical ventilation. Biometrical J, 2018; 60 (6): 1135-1150. : http://dx.doi.org/10.1002/bimj.201700242
  • de Kraker MEA, Sommer H, de Velde F, Gravestock I, Weiss E, McAleenan A, Nikolakopoulos S, Amit O, Ashton T, Beyersmann J, Held L, Lovering AM, MacGowan AP, Mouton JW, Timsit JF, Wilson D, Wolkewitz M, Bettiol E, Dane A, Harbarth S, COMBACTE-NET Consortium: Optimizing the Design and Analysis of Clinical Trials for Antibacterials Against Multidrug-resistant Organisms: A White Paper From COMBACTE's STAT-Net. Clin Infect Dis, 2018; 67: 1922-1931. : https://doi.org/10.1093/cid/ciy516
  • Hazard D, Schumacher M, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Wolkewitz M: Improving nested case-control studies to conduct a full competing-risks analysis for nosocomial infections. Infect Cont Hosp Ep, 2018; 39 (10): 1196-1201. : https://doi.org/10.1017/ice.2018.186
  • Paling FP, Olsen K, Ohneberg K, Wolkewitz M, Fowler VG Jr, DiNubile MJ, Jafri HS, Sifakis F, Bonten MJM, Harbarth SJ, Kluytmans JAJW: Risk prediction for Staphylococcus aureus surgical site infection following cardiothoracic surgery; A secondary analysis of the V710-P003 trial. Plos One, 2018; 13 (3) (online): e0193445-e0193445. : http://dx.doi.org/10.1371/journal.pone.0193445
  • Poguntke I, Schumacher M, Beyersmann J, Wolkewitz M, On Behalf Of Combacte-Magnet Consortium MW: Simulation shows undesirable results for competing risks analysis with time-dependent covariates for clinical outcomes. Bmc Med Res Methodol, 2018; 18 (online): 79. : https://doi.org/10.1186/s12874-018-0535-5
  • Rahman S, von Cube M, Schumacher M, Wolkewitz M: Bias due to censoring of deaths when calculating extra length of stay for patients acquiring a hospital infection. Bmc Med Res Methodol, 2018; 18 (online): 49. : https://doi.org/10.1186/s12874-018-0500-3
  • Sommer H, Timsit JF, von Cube M, Schumacher M, Darmon M, Schwebel C, Ruckly S, Wolkewitz M, COMBACTE-MAGNET Consortium.: The Impact of Early Adequate Treatment on Extubation and Discharge Alive of Patients With Pseudomonas aeruginosa-Related Ventilator-Associated Pneumonia. Crit Care Med, 2018; 46: 1643-1648. : https://doi.org/10.1097/CCM.0000000000003305
  • van der Kooi T, Sax H, Pittet D, van Dissel J, van Benthem B, Walder B, Cartier V, Clack L, de Greeff S, Wolkewitz M, Hieke S, Boshuizen H, van de Kassteele J, Van den Abeele A, Boo TW, Diab-Elschahawi M, Dumpis U, Ghita C, FitzGerald S, Lejko T, Leleu K, Martinez MP, Paniara O, Patyi M, Schab P, Raglio A, Szilágyi E, Ziętkiewicz M, Wu AW, Grundmann H, Zingg W, PROHIBIT consortium: Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections. Intens Care Med, 2018; 44: 48-60. : https://doi.org/10.1007/s00134-017-5007-6
  • Vukovic E, Czerny M, Beyersdorf F, Wolkewitz M, Berezowski M, Siepe M, Blanke P, Rylski B: Abdominal aortic aneurysm neck remodeling after Anaconda stent graft implantation. J Vasc Surg, 2018; 68 (5): 1354-1359.e2. : http://dx.doi.org/10.1016/j.jvs.2018.02.041
  • Wolkewitz M, Mandel M, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Schumacher M.: Methodological challenges in using point-prevalence versus cohort data in risk factor analyses of nosocomial infections. Ann Epidemiol, 2018; 28: 475-480. : https://doi.org/10.1016/j.annepidem.2018.03.017
Short Communications:
  • Weber S, Wolkewitz M, Schumacher M: Analyzing the impact of depth of response on survival in patients with metastatic non-small-cell lung cancer. Ann Oncol, 2018; 29: 282-283. : https://doi.org/10.1093/annonc/mdx558
Other publications (type Sonstiges):
  • Doerken S, Mandel M, Zingg W, Wolkewitz M: Use of prevalence data to study sepsis incidence and mortality in intensive care units. Lancet Infect Dis, 2018; 18 (3) : 252-252. : http://dx.doi.org/10.1016/S1473-3099(18)30081-1
  • Heister T, Wolkewitz M, Kaier K: Determining the Attributable Costs of Clostridium difficile Infections When Exposure Time Is Lacking: Be Wary of "Conditioning on the Future". Infect Cont Hosp Ep, 2018; 39: 759-760. : https://doi.org/10.1017/ice.2018.42
  • Heister T, Wolkewitz M, Kaier K: Estimating the additional costs of surgical site infections: length bias, time-dependent bias, and conditioning on the future. J Hosp Infect, 2018; 99: 103-104. : https://doi.org/10.1016/j.jhin.2018.02.012
  • Kaier K, Wolkewitz M, Heister T: Estimating the attributable costs of hospital-acquired infections requires a distinct categorization of cases based on time of infection. Am J Infect Control, 2018; 46: 729. : https://doi.org/10.1016/j.ajic.2018.02.014
  • von Cube MK, Timsit JF, Sommer H, Darmon M, Schwebel C, Bailly S, Souweine B, Wolkewitz M: Relative risk and population-attributable fraction of ICU death caused by susceptible and resistant Pseudomonas aeruginosa ventilator-associated pneumonia: a competing risks approach to investigate the OUTCOMEREA database. Intens Care Med, 2018; 44 (7) : 1177-1179. : http://dx.doi.org/10.1007/s00134-018-5109-9