Forschungsbericht für das Jahr 2018

Institut für Medizinische Biometrie und Statistik

Stefan-Meier-Strasse 26
79104 Freiburg
Tel: 0761 203 6662 Fax: 0761 203 6680
Email sec@imbi.uni-freiburg.de
http://www.imbi.uni-freiburg.de


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. M. Schumacher
  • Prof. Dr. J. Schulte Mönting
  • Arthur Allignol
  • Dr. G. Antes
  • Dr. J. Beyersmann
  • Dr. H. Binder
  • Dr. Anette Blümle
  • D. Booker
  • Dipl.-Stat. Anika Buchholz
  • Dr. A. Caputo
  • Dr. J. Carpenter
  • Dr. Erik von Elm
  • Dipl.-Math. C. Gall
  • Dr. T. Gerds
  • Dipl.-Stat. A. Gerlach
  • Dr. E. Graf
  • Prof. Dr. Dieter Hauschke
  • Dr. G. Ihorst
  • Dr. B. Lang
  • Dr. Jörg Meerpohl
  • Dipl.-Stat. M. Olschewski
  • Dipl.-Stat. Christine Porzelius
  • Dipl.-Math. G. Rücker
  • PD Dr. W. Sauerbrei
  • Dr. C. Schmoor
  • Dr. Christine Schmucker
  • Dipl.-Math.Oec. R. Schoop
  • Dr. G. Schwarzer
  • Dipl.-Math. P. Sekula
  • Dipl.-Stat. S. Stampf
  • PD Dr. A. Timmer
  • Robert Wolff
  • Dr. M. Wolkewitz
Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Biometrische Methodologie
  • Epidemiologische Studien
  • Klinische Studien
  • Multizentrische Therapiestudien

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Bender R, Friede T, Koch A, Kuss O, Schlattmann P, Schwarzer G, Skipka G: Methods for evidence synthesis in the case of very few studies. Res Synth Methods, 2018; 9 (3): 382-392. : http://dx.doi.org/10.1002/jrsm.1297
  • Brinster R, Köttgen A, Tayo BO, Schumacher M, Sekula P, CKDGen Consortium: Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation. Bmc Bioinformatics, 2018; 19 (online): 78-78. : https://doi.org/10.1186/s12859-018-2081-x
  • Byrne J, Grabow D, Campbell H, O'Brien K, Bielack S, Am Zehnhoff-Dinnesen, Calaminus G, Kremer L, Langer T, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Baust K, Bautz A, Beck JD, Berger C, Binder H, Borgmann-Staudt A, Broer L, Cario H, Casagranda L, Clemens E, Deuster D, de Vries A, Dirksen U, Falck Winther J, Fosså S, Font-Gonzalez A, Grandage V, Haupt R, Hecker-Nolting S, Hjorth L, Kaiser M, Kenborg L, Kepak T, Kepáková K, Knudsen LE, Krawczuk-Rybak M, Kruseova J, Kuehni CE, Kunstreich M, Kuonen R, Lackner H, Leiper A, Loeffen EAH, Luks A, Modan-Moses D, Mulder R, Parfitt R, Paul NW, Ranft A, Ruud E, Schilling R, Spix C, Stefanowicz J, Strauβ G, Uitterlinden AG, van den Berg M, van der Kooi AL, van Dijk M, van Leeuwen F, Zolk O, Zöller D, Kaatsch P, PanCareLIFE consortium: PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents. Eur J Cancer, 2018; 103: 227-237. : https://doi.org/10.1016/j.ejca.2018.08.007
  • De Bin R, Sauerbrei W: Handling co-dependence issues in resampling-based variable selection procedures: a simulation study. J Stat Comput Sim, 2018; 88 (1): 28-55. : http://dx.doi.org/10.1080/00949655.2017.1378654
  • Grigioni F, Clavel MA, Vanoverschelde JL, Tribouilloy C, Pizarro R, Huebner M, Avierinos JF, Barbieri A, Suri R, Pasquet A, Rusinaru D, Gargiulo GD, Oberti P, Théron A, Bursi F, Michelena H, Lazam S, Szymanski C, Nkomo VT, Schumacher M, Bacchi-Reggiani L, Enriquez-Sarano M, MIDA Investigators: The MIDA Mortality Risk Score: development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation. Eur Heart J, 2018; 39: 1281-1291. : https://doi.org/10.1093/eurheartj/ehx465
  • Jabbarli R, Pierscianek D, Rölz R, Reinhard M, Darkwah Oppong M, Scheiwe C, Dammann P, Kaier K, Wrede KH, Shah M, Zentner J, Sure U: Gradual External Ventricular Drainage Weaning Reduces The Risk of Shunt Dependency After Aneurysmal Subarachnoid Hemorrhage: A Pooled Analysis. Oper Neurosurg, 2018; 15 (5): 498-504. : https://doi.org/10.1093/ons/opy009
  • Jayasekera J, Li Y, Schechter CB, Jagsi R, Song J, White J, Luta G, Chapman JW, Feuer EJ, Zellars RC, Stout N, Julian TB, Whelan T, Huang X, Shelley Hwang E, Hopkins JO, Sparano JA, Anderson SJ, Fyles AW, Gray R, Sauerbrei W, Mandelblatt J, Berry DA, CISNET-BOLD Collaborative Group: Simulation Modeling of Cancer Clinical Trials: Application to Omitting Radiotherapy in Low-risk Breast Cancer. Jnci-j Natl Cancer I, 2018; 110 (12): 1360-1369. : https://doi.org/10.1093/jnci/djy059
  • Jayasekera J, Schechter CB, Sparano JA, Jagsi R, White J, Chapman JW, Whelan T, Anderson SJ, Fyles AW, Sauerbrei W, Zellars RC, Li Y, Song J, Huang X, Julian TB, Luta G, Berry DA, Feuer EJ, Mandelblatt J, CISNET-BOLD Collaborative Group: Effects of Radiotherapy in Early-Stage, Low-Recurrence Risk, Hormone-Sensitive Breast Cancer. Jnci-j Natl Cancer I, 2018; 110 (12): 1370-1379. : https://doi.org/10.1093/jnci/djy128
  • Kempf E, de Beyer JA, Cook J, Holmes J, Mohammed S, Nguyen TL, Simera I, Trivella M, Altman DG, Hopewell S, Moons KGM, Porcher R, Reitsma JB, Sauerbrei W, Collins GS: Overinterpretation and misreporting of prognostic factor studies in oncology: a systematic review. Brit J Cancer, 2018; 119 (10): 1288-1296. : http://dx.doi.org/10.1038/s41416-018-0305-5
  • Kohal R, Fross A, Adolfsson E, Bagegni A, Doerken S, Spies BC: Fatigue resistance of a two‐piece zirconia oral implant. An investigation in the chewing simulator. Clin Oral Implan Res, 2018; 29 Suppl. 17: 54. : https://doi.org/10.1111/clr.11_13356
  • Kowalzik F, Binder H, Zöller D, Riera-Montes M, Clemens R, Verstraeten T, Zepp F: Norovirus Gastroenteritis among Hospitalized Patients, Germany, 2007-2012. Emerg Infect Dis, 2018; 24: 2021-2028. : https://doi.org/10.3201/eid2411.170820
  • Lamparter J, Schmidtmann I, Schuster AK, Siouli A, Wasielica-Poslednik J, Mirshahi A, Höhn R, Unterrainer J, Wild PS, Binder H, Lackner K, Beutel ME, Münzel T, Pfeiffer N, Hoffmann EM: Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness. Plos One, 2018; 13 (online): e0197682. : https://doi.org/10.1371/journal.pone.0197682
  • Nührenberg TG, Cederqvist M, Marini F, Stratz C, Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann F-J, Hein L: Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome. Biomed Res Int, 2018; 2018 (online): 8989252. : https://doi.org/10.1155/2018/8989252
  • Schwab C, Gabrysch A, Olbrich P, Patino V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom DM, Lucena JM, Seidl M, Schmitt-Graeff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Sumnik Z, Sediva A, Slatter M, Arkwright PD, Cant A, Lorenz HM, Giese T, Lougaris V, Plebani A, Price C, Sullivan KE, Moutschen M, Litzman J, Freiberger T, van de Veerdonk FL, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Speckmann C, Ehl S, Leichtner A, Blumberg R, Franke A, Snapper S, Zeissig S, Cunningham-Rundles C, Giulino-Roth L, Elemento O, Duckers G, Niehues T, Fronkova E, Kanderova V, Platt CD, Chou J, Chatila TA, Geha R, McDermott E, Bunn S, Kurzai M, Schulz A, Alsina L, Casals F, Deya-Martinez A, Hambleton S, Kanegane H, Tasken K, Neth O, Grimbacher B: Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects. J Allergy Clin Immun, 2018; 142 (6): 1932-1946. : http://dx.doi.org/10.1016/j.jaci.2018.02.055
  • Sommer S, Cruijsen M, Claus R, Bertz H, Wasch R, Marks R, Zeiser R, Bogatyreva L, Blijlevens NMA, May A, Duyster J, Huls G, van der Velden WJFM, Finke J, Lubbert M: Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation. Leukemia Res, 2018; 72: 20-26. : http://dx.doi.org/10.1016/j.leukres.2018.07.005
  • Taschner CA, Chapot R, Costalat V, Machi P, Courthéoux P, Barreau X, Berge J, Pierot L, Kadziolka K, Jean B, Blanc R, Biondi A, Brunel H, Gallas S, Berlis A, Herbreteau D, Berkefeld J, Urbach H, Elsheikh S, Fiehler J, Desal H, Graf E, Bonafé A: Second-Generation Hydrogel Coils for the Endovascular Treatment of Intracranial Aneurysms. A Randomized Controlled Trial. Stroke, 2018; 49: 667-674. : https://doi.org/10.1161/STROKEAHA.117.018707
  • Torbahn G, Hofmann H, Rücker G, Bischoff K, Freitag MH, Dersch R, Fingerle V, Motschall E, Meerpohl JJ, Schmucker C: Efficacy and Safety of Antibiotic Therapy in Early Cutaneous Lyme Borreliosis: A Network Meta-analysis. Jama Dermatol, 2018; 154 (11): 1292-1303. : https://doi.org/10.1001/jamadermatol.2018.3186

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten