Scientific publications
Journal Articles:
- Andrlová H, Mastroianni J, Madl J, Kern JS, Melchinger W, Dierbach H, Wernet F, Follo M, Technau-Hafsi K, Has C, Mittapalli VR, Idzko M, Herr R, Brummer T, Ungefroren H, Busch H, Boerries M, Narr A, Ihorst G, Vennin C, Schmitt-Graeff A, Minguet S, Timpson P, Duyster J, Meiss F, Römer W, Zeiser R: Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression. Oncotarget, 2017; 8: 42901-42916. : https://doi.org/10.18632/oncotarget.17160
- Böger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, Navis G, Nolte IM, de Borst MH, Zhang W, Lehne B, Loh M, Tan ST, Boerwinkle E, Grams ME, Sekula P, Li M, Wilmot B, Moon JG, Scheet P, Cucca F, Xiao X, Lyytikäinen LP, Delgado G, Grammer TB, Kleber ME, Sedaghat S, Rivadeneira F, Corre T, Kutalik Z, Bergmann S, Nielson CM, Srikanth P, Teumer A, Müller-Nurasyid M, Brockhaus AC, Pfeufer A, Rathmann W, Peters A, Matsumoto M, de Andrade M, Atkinson EJ, Robinson-Cohen C, de Boer IH, Hwang SJ, Heid IM, Gögele M, Concas MP, Tanaka T, Bandinelli S, Nalls MA, Singleton A, Tajuddin SM, Adeyemo A, Zhou J, Doumatey A, McWeeney S, Murabito J, Franceschini N, Flessner M, Shlipak M, Wilson JG, Chen G, Rotimi CN, Zonderman AB, Evans MK, Ferrucci L, Devuyst O, Pirastu M, Shuldiner A, Hicks AA, Pramstaller PP, Kestenbaum B, Kardia SL, Turner ST, LifeLines Cohort Study, Briske TE, Gieger C, Strauch K, Meisinger C, Meitinger T, Völker U, Nauck M, Völzke H, Vollenweider P, Bochud M, Waeber G, Kähönen M, Lehtimäki T, März W, Dehghan A, Franco OH, Uitterlinden AG, Hofman A, Taylor HA, Chambers JC, Kooner JS, Fox CS, Hitzemann R, Orwoll ES, Pattaro C, Schlessinger D, Köttgen A, Snieder H, Parsa A, Cohen DM: NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. J Am Soc Nephrol, 2017; 28: 2311-2321. : https://doi.org/10.1681/ASN.2016080892
- Engelhardt M, Domm A-S, Dold SM, Ihorst G, Reinhardt H, Zober A, Hieke S, Baayen C, Müller SJ, Einsele H, Sonneveld P, Landgren O, Schumacher M, Wäsch R: A concise revised myeloma comorbidity Index as a valid prognostic instrument in a large cohort of 801 multiple myeloma patients. Haematologica, 2017; 102: 910-921. : http://dx.doi.org/10.3324/haematol.2016.162693
- Finke J, Schmoor C, Bethge WA, Ottinger H, Stelljes M, Volin L, Heim D, Bertz H, Grishina O, Socie G: Long-term outcomes after standard graft-versus-host disease prophylaxis with or without anti-human-T-lymphocyte immunoglobulin in haemopoietic cell transplantation from matched unrelated donors: final results of a randomised controlled trial. Lancet Haematol, 2017; 4 (6): e293-e301. : https://doi.org/10.1016/S2352-3026(17)30081-9
- Fritsch K, Kasenda B, Schorb E, Hau P, Bloehdorn J, Möhle R, Löw S, Binder M, Atta J, Keller U, Wolf H-H, Krause SW, Heß G, Naumann R, Sasse S, Hirt C, Lamprecht M, Martens U, Morgner A, Panse J, Frickhofen N, Röth A, Hader C, Deckert M, Fricker H, Ihorst G, Finke J, Illerhaus G: High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study). Leukemia, 2017; 31: 846-852. : https://dx.doi.org/10.1038/leu.2016.334
- Greil C, Ihorst G, Gaiser F, Salzer U, Bisse E, Kastritis E, Ludwig H, Wäsch R, Engelhardt M: The serum heavy/light chain immunoassay: A valuable tool for sensitive paraprotein assessment, risk, and disease monitoring in monoclonal gammopathies. Eur J Haematol, 2017; 99: 449-458. : https://doi.org/10.1111/ejh.12958
- Gutmann A, Kaier K, Reinecke H, Frankenstein L, Zirlik A, Bothe W, von Zur Mühlen C, Zehender M, Reinöhl J, Bode C, Stachon P: Impact of pulmonary hypertension on in-hospital outcome after surgical or transcatheter aortic valve replacement. Eurointervention, 2017; 13 (7): 804-810. : http://dx.doi.org/10.4244/EIJ-D-16-00927
- Hess M, Lenz S, Blätte TJ, Bullinger L, Binder H: Partitioned learning of deep Boltzmann machines for SNP data. Bioinformatics, 2017; 33: 3173-3180. : https://doi.org/10.1093/bioinformatics/btx408
- Hinderer M, Boeker M, Wagner SA, Binder H, Uckert F, Newe S, Hulsemann JL, Neumaier M, Schade-Brittinger C, Acker T, Prokosch HU, Sedlmayr B: The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals. Pharmacogenomics, 2017; 18 (8): 773-785. : http://dx.doi.org/10.2217/pgs-2017-0027
- Hinderer M, Boeker M, Wagner SA, Lablans M, Newe S, Hulsemann JL, Neumaier M, Binder H, Renz H, Acker T, Prokosch HU, Sedlmayr M: Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development. Bmc Med Inform Decis, 2017; 17 (1) (online): 81. : http://dx.doi.org/10.1186/s12911-017-0480-y
- Jahn-Eimermacher A, Ingel K, Preussler S, Bayes-Genis A, Binder H: A DAG-based comparison of interventional effect underestimation between composite endpoint and multi-state analysis in cardiovascular trials. Bmc Med Res Methodol, 2017; 17 (1) (online): 92. : http://dx.doi.org/10.1186/s12874-017-0366-9
- Jansen L, Weberpals J, Kuiper JG, Vissers PAJ, Wolkewitz M, Hoffmeister M, Brenner H: Pre- and post-diagnostic beta-blocker use and prognosis after colorectal cancer: Results from a population-based study. Int J Cancer, 2017; 141: 62-71. : http://dx.doi.org/10.1002/ijc.30717
- Kaier K, Reinecke H, Schmoor C, Frankenstein L, Vach W, Hehn P, Zirlik A, Bode C, Zehender M, Reinöhl J: Learning Curves Among All Patients Undergoing Transcatheter Aortic Valve Implantation in Germany: A Retrospective Observational Study. Int J Cardiol, 2017; 235: 17-21. : https://doi.org/10.1016/j.ijcard.2017.02.138
- Kaier K, von Kampen F, Baumbach H, von Zur Muhlen C, Hehn P, Vach W, Zehender M, Bode C, Reinöhl J: Two-year post-discharge costs of care among patients treated with transcatheter or surgical aortic valve replacement in Germany. Bmc Health Serv Res, 2017; 17 (1) (online): 473. : http://dx.doi.org/10.1186/s12913-017-2432-8
- Kampling H, Petrak F, Farin E, Kulzer B, Herpertz S, Mittag O: Trajectories of depression in adults with newly diagnosed type 1 diabetes: results from the German Multicenter Diabetes Cohort Study Diabetologia, 2017; 60 (1): 60-68.
- Karrasch S, Linde K, Rücker G, Sommer H, Karsch-Völk M, Kleijnen J, Jörres RA, Schneider A: Accuracy of FENO for diagnosing asthma: a systematic review. Thorax, 2017; 72: 109-116. : http://dx.doi.org/10.1136/thoraxjnl-2016-208704
- Kasenda B, Ihorst G, Schroers R, Korfel A, Schmidt-Wolf I, Egerer G, von Baumgarten L, Röth A, Bloehdorn J, Möhle R, Binder M, Keller U, Lamprecht M, Pfreundschuh M, Valk E, Fricker H, Schorb E, Fritsch K, Finke J, Illerhaus G: High-dose chemotherapy with autologous haematopoietic stem cell support for relapsed or refractory primary CNS lymphoma: a prospective multicentre trial by the German Cooperative PCNSL study group. Leukemia, 2017; 31: 2623-2629. : https://doi.org/10.1038/leu.2017.170
- Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galie N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jimenez D, Kozak M, Lang IM, Lankeit M, Munzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV: Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thromb Haemostasis, 2017; 117 (12): 2425-2434. : http://dx.doi.org/10.1160/TH17-06-0434
- Lin J, Sander L, Paganini S, Schlicker S, Ebert D, Berking M, Bengel J, Nobis S, Lehr D, Mittag O, Riper H, Baumeister H: Effectiveness and cost-effectiveness of a
guided internet- and mobile-based
depression intervention for individuals
with chronic back pain: protocol of a
multi-centre randomised controlled trial Bmj Open, 2017; 7 (online): e015226. : http://dx.doi.org/10.1136/bmjopen-2016-015226
- Lorenz E, Jenkner C, Sauerbrei W, Becher H: Modeling Variables With a Spike at Z ero: Examples and Practical Recommendations: Am J Epidemiol, 2017; 185: 650-660. : https://doi.org/10.1093/aje/kww122
- Lübbert M, Ihorst G, Sander PN, Bogatyreva L, Becker H, Wijermans PW, Suciu S, Bissé E, Claus R: Elevated fetal haemoglobin is a predictor of better outcome in MDS/AML patients receiving 5-aza-2′-deoxycytidine (Decitabine). Brit J Haematol, 2017; 176: 609-617. : https://dx.doi.org/10.1111/bjh.14463
- Lüders F, Kaier K, Kaleschke G, Gebauer K, Meyborg M, Malyar NM, Freisinger E, Baumgartner H, Reinecke H, Reinöhl J: Association of CKD with Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation. Clin J Am Soc Nephro, 2017; 12 (5): 718-726. : http://dx.doi.org/10.2215/CJN.10471016
- Malyar NM, Kaier K, Freisinger E, Luders F, Kaleschke G, Baumgartner H, Frankenstein L, Reinecke H, Reinohl J: Prevalence and Impact of Critical Limb Ischaemia on In-Hospital Outcome in Transcatheter Aortic Valve Implantation in Germany. Eurointervention, 2017; 13 (11): 1281-1287. : http://dx.doi.org/10.4244/EIJ-D-17-00228
- Mittag O, Brendel L, Schlöffel M, Pollmann H: Testung und Kalibrierung eines Fragebogensets zur späteren webbasierten Erfassung von Rehabilitationsbedarf bei Versicherten der Deutschen Rentenversicherung (Online-Rehabedarfstest) Prävention und Rehabilitation, 2017; 29 (2): 62-69. : http://dx.doi.org/10.5414/PRX0508
- Paling FP, Troeman DPR, Wolkewitz M, Kalyani R, Prins DR, Weber S, Lammens C, Timbermont L, Goossens H, Malhotra-Kumar S, Sifakis F, Bonten MJM, Kluytmans JAJW: Rationale and design of ASPIRE-ICU: a prospective cohort study on the incidence and predictors of Staphylococcus aureus and Pseudomonas aeruginosa pneumonia in the ICU. Bmc Infect Dis, 2017; 17: 643. : https://doi.org/10.1186/s12879-017-2739-4
- Schulz A, Zoeller D, Nickels S, Beutel ME, Blettner M, Wild PS, Binder H: Simulation of complex data structures for planning of studies with focus on biomarker comparison. Bmc Med Res Methodol, 2017; 17 (1) (online): 90. : http://dx.doi.org/10.1186/s12874-017-0364-y
- Simonsen JA, Mickley H, Johansen A, Hess1 S, Thomassen A, Gerke O, Jensen LO, Hallas J, Vach W, Hoilund-Carlsen PF: Outcome of revascularization in stable coronary artery disease without ischaemia: a Danish registry-based follow-up study. Bmj Open, 2017; 7 (8) (online): e016169. : http://bmjopen.bmj.com/content/7/8/e016169
- Sommer H, Wolkewitz M, Schumacher M, COMBACTE-NET consortium: The time-dependent "cure-death" model investigating two equally important endpoints simultaneously in trials treating high-risk patients with resistant pathogens. Pharm Stat, 2017; 16: 267-279. : https://doi.org/10.1002/pst.1809
- Timsit J-F, de Kraker MEA, Sommer H, Weiss E, Bettiol E, Wolkewitz M, Nikolakopoulos S, Wilson D, Harbarth S, on behalf of the COMBACTE-NET consortium: Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE’s STAT-Net. Intens Care Med, 2017; 43: 1002-1012. : http://dx.doi.org/10.1007/s00134-017-4802-4
- Weberpals J, Jansen L, Haefeli WE, Hoffmeister M, Wolkewitz M, Herk-Sukel MPPV, Vissers PAJ, Brenner H: Pre- and post-diagnostic β-blocker use and lung cancer survival: A population-based cohort study. Sci Rep-uk, 2017; 7 (online): 2911. : https://doi.org/10.1038/s41598-017-02913-8
- Wuensch A, Goelz T, Ihorst G, Terris DD, Bertz H, Bengel J, Wirsching M, Fritzsche K: Effect of individualized communication skills training on physicians’ discussion of clinical trials in oncology: results from a randomized controlled trial. Bmc Cancer, 2017; 17 (online): 264. : https://doi.org/10.1186/s12885-017-3238-0
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