Research Report for the year 2017

Scientific publications

Journal Articles:
  • Böger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, Navis G, Nolte IM, de Borst MH, Zhang W, Lehne B, Loh M, Tan ST, Boerwinkle E, Grams ME, Sekula P, Li M, Wilmot B, Moon JG, Scheet P, Cucca F, Xiao X, Lyytikäinen LP, Delgado G, Grammer TB, Kleber ME, Sedaghat S, Rivadeneira F, Corre T, Kutalik Z, Bergmann S, Nielson CM, Srikanth P, Teumer A, Müller-Nurasyid M, Brockhaus AC, Pfeufer A, Rathmann W, Peters A, Matsumoto M, de Andrade M, Atkinson EJ, Robinson-Cohen C, de Boer IH, Hwang SJ, Heid IM, Gögele M, Concas MP, Tanaka T, Bandinelli S, Nalls MA, Singleton A, Tajuddin SM, Adeyemo A, Zhou J, Doumatey A, McWeeney S, Murabito J, Franceschini N, Flessner M, Shlipak M, Wilson JG, Chen G, Rotimi CN, Zonderman AB, Evans MK, Ferrucci L, Devuyst O, Pirastu M, Shuldiner A, Hicks AA, Pramstaller PP, Kestenbaum B, Kardia SL, Turner ST, LifeLines Cohort Study, Briske TE, Gieger C, Strauch K, Meisinger C, Meitinger T, Völker U, Nauck M, Völzke H, Vollenweider P, Bochud M, Waeber G, Kähönen M, Lehtimäki T, März W, Dehghan A, Franco OH, Uitterlinden AG, Hofman A, Taylor HA, Chambers JC, Kooner JS, Fox CS, Hitzemann R, Orwoll ES, Pattaro C, Schlessinger D, Köttgen A, Snieder H, Parsa A, Cohen DM: NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. J Am Soc Nephrol, 2017; 28: 2311-2321. :
  • Bollig C, Schell LK, Rücker G, Allert R, Motschall E, Niemeyer CM, Bassler D, Meerpohl JJ: Deferasirox for managing iron overload in people with thalassaemia. Cochrane Db Syst Rev, 2017; 8 (online): CD007476. :
  • Brinkhaus B, Roll S, Jena S, Icke K, Adam D, Binting S, Lotz F, Willich SN, Witt CM: Acupuncture in Patients with Allergic Asthma: A Randomized Pragmatic Trial. J Altern Complem Med, 2017; 23 (4): 268-277. :
  • Döpfner M, Hautmann C, Dose C, Banaschewski T, Becker K, Brandeis D, Holtmann M, Jans T, Jenkner C, Millenet S, Renner T, Romanos M, von Wirth E: ESCAschool study: trial protocol of an adaptive treatment approach for school-age children with ADHD including two randomised trials. Bmc Psychiatry, 2017; 17 (1) (online): 269. :
  • Eismann J, Hirschfeld M, Erbes T, Rücker G, Jäger M, Ritter A, Weiss D, Gitsch G, Mayer S: Hypoxia- and acidosis-driven aberrations of secreted microRNAs in endometrial cancer in vitro. Oncol Rep, 2017; 38: 993-1004. :
  • Finke J, Schmoor C, Bethge WA, Ottinger H, Stelljes M, Volin L, Heim D, Bertz H, Grishina O, Socie G: Long-term outcomes after standard graft-versus-host disease prophylaxis with or without anti-human-T-lymphocyte immunoglobulin in haemopoietic cell transplantation from matched unrelated donors: final results of a randomised controlled trial. Lancet Haematol, 2017; 4 (6): e293-e301. :
  • Gaertner J, Siemens W, Meerpohl JJ, Antes G, Meffert C, Xander C, Stock S, Mueller D, Schwarzer G, Becker G: Effect of specialist palliative care services on quality of life in adults with advanced incurable illness in hospital, hospice, or community settings: systematic review and meta-analysis. Bmj-brit Med J, 2017; 357 (online): j2925. :
  • Hein S, Schoenthaler M, Wilhelm K, Schlager D, Vach W, Wetterauer U, Miernik A: Ultralow Radiation Exposure During Flexible Ureteroscopy in Patients With Nephrolithiasis-How Far Can We Go? Urology, 2017; 108: 34-39. :
  • Hochholzer W, Kleiner P, Younas I, Valina CM, Löffelhardt N, Amann M, Bömicke T, Ferenc M, Hauschke D, Trenk D, Neumann FJ, Stratz C: Randomized Comparison of Oral P2Y12-Receptor Inhibitor Loading Strategies for Transitioning From Cangrelor: The ExcelsiorLOAD2 Trial. Jacc-cardiovasc Inte, 2017; 10: 121-129. :
  • Jackson D, Law M, Rücker G, Schwarzer G: The Hartung-Knapp modification for random-effects meta-analysis: A useful refinement but are there any residual concerns? Stat Med, 2017; 36: 3923-3934. :
  • Kaier K, Hils S, Fetzer S, Hehn P, Schmid A, Hauschke D, Bogatyreva L, Jänigen B, Pisarski P: Results of a randomized controlled trial analyzing telemedically supported case management in the first year after living donor kidney transplantation - a budget impact analysis from the healthcare perspective. Health Economics Review, 2017; 7 (online): 1. :
  • Kaufmann KB, Stein L, Bogatyreva L, Ulbrich F, Kaifi JT, Hauschke D, Loop T, Goebel U: Oesophageal Doppler guided goal-directed haemodynamic therapy in thoracic surgery - a single centre randomized parallel-arm trial. Brit J Anaesth, 2017; 118: 852-861. :
  • Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galie N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jimenez D, Kozak M, Lang IM, Lankeit M, Munzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV: Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thromb Haemostasis, 2017; 117 (12): 2425-2434. :
  • Limberger KA, Bogatyreva L, Todorova R, Herde B, Hauschke D, Pahl HL, Werner M, Aumann K: Tissue microarray technique is applicable to bone marrow biopsies of myeloproliferative neoplasms. Histochem Cell Biol, 2017; 147: 75-82. :
  • Lin J, Sander L, Paganini S, Schlicker S, Ebert D, Berking M, Bengel J, Nobis S, Lehr D, Mittag O, Riper H, Baumeister H: Effectiveness and cost-effectiveness of a guided internet- and mobile-based depression intervention for individuals with chronic back pain: protocol of a multi-centre randomised controlled trial Bmj Open, 2017; 7 (online): e015226. :
  • Magnet FS, Callegari J, Dieninghoff D, Spielmanns M, Storre JH, Schmoor C, Windisch W: Impact of Pseudomonas aeruginosa Infection on Respiratory Muscle Function in Adult Cystic Fibrosis Patients. Respiration, 2017; 93: 42-50. :
  • Mayer S, Kayser G, Rücker G, Bögner D, Hirschfeld M, Hug C, Stickeler E, Gitsch G, Erbes T: Absence of epithelial atypia in B3-lesions of the breast is associated with decreased risk for malignancy. Breast, 2017; 31: 144-149. :
  • Reese C, Weis J, Schmucker D, Mittag O: Development of practice guidelines for psychological interventions in the rehabilitation of patients with oncological disease (breast, prostate, or colorectal cancer): Methods and results. Psycho-oncology, 2017; 26: 1513-1518. :
  • Schmid A, Hils S, Kramer-Zucker A, Bogatyreva L, Hauschke D, De Geest S, Pisarski P: Telemedically-supported case management of living-donor renal transplant recipients to optimize routine evidence-based aftercare: A single-center randomized controlled trial. Am J Transplant, 2017; 17: 1594-1605. :
  • Schoeb DS, Schlager D, Boeker M, Wetterauer U, Schoenthaler M, Herrmann TRW, Miernik A: Surgical therapy of prostatitis: a systematic review. World J Urol, 2017; 35 (11): 1659-1668. :
  • Schulz A, Zoeller D, Nickels S, Beutel ME, Blettner M, Wild PS, Binder H: Simulation of complex data structures for planning of studies with focus on biomarker comparison. Bmc Med Res Methodol, 2017; 17 (1) (online): 90. :
  • Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P, GCKD Investigators, Eckardt K-U, Kronenberg F, Kleta R, Köttgen A: Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Nephrol Dial Transpl, 2017; 32: 325-332. :
  • Sillem M, Timme S, Bronsert P, Bogatyreva L, Hauschke D, Zur Hausen A, Werner M, Stickeler E: Anti-Phosphohistone H3-Positive Mitoses Are Linked to Pathological Response in Neoadjuvantly Treated Breast Cancer. Breast Care, 2017; 12: 244-250. :
  • Speckmann C, Doerken S, Aiuti A, Albert MH, Al-Herz W, Allende LM, Scarselli A, Avcin T, Perez-Becker R, Cancrini C, Cant A, Di Cesare S, Finocchi A, Fischer A, Gaspar HB, Ghosh S, Gennery A, Gilmour K, González-Granado LI, Martinez-Gallo M, Hambleton S, Hauck F, Hoenig M, Moshous D, Neven B, Niehues T, Notarangelo L, Picard C, Rieber N, Schulz A, Schwarz K, Seidel MG, Soler-Palacin P, Stepensky P, Strahm B, Vraetz T, Warnatz K, Winterhalter C, Worth A, Fuchs S, Uhlmann A, Ehl S, on behalf of the P-CID study of the Inborn Errors Working Party of the EBMT: A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis. J Allergy Clin Immun, 2017; 139: 1302-1310.e4. :
  • Timsit J-F, de Kraker MEA, Sommer H, Weiss E, Bettiol E, Wolkewitz M, Nikolakopoulos S, Wilson D, Harbarth S, on behalf of the COMBACTE-NET consortium: Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE’s STAT-Net. Intens Care Med, 2017; 43: 1002-1012. :
  • Waldschmidt JM, Simon A, Wider D, Müller SJ, Follo M, Ihorst G, Decker S, Lorenz J, Chatterjee M, Azab AK, Duyster J, Wäsch R, Engelhardt M: CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma. Brit J Haematol, 2017; 179: 36-49. :
  • Wehrum T, Dragonu I, Strecker C, Schuchardt F, Hennemuth A, Drexl J, Reinhard T, Bohringer D, Vach W, Hennig J, Harloff A: Aortic atheroma as a source of stroke - assessment of embolization risk using 3D CMR in stroke patients and controls. J Cardiovasc Magn R, 2017; 19 (1) (online): 67. :
  • Weibel S, Jelting Y, Pace NL, Rücker G, Raj D, Schaefer MS, Backhaus I, Kienbaum P, Eberhart LHJ, Kranke P: Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis. (Protocol). Cochrane Db Syst Rev, 2017; 11 (online): CD012859. : (in Druck)
Conference Papers:
  • Kempf E, Porcher R, de Beyer J, Moons K, Altman D, Reitsma H, Hopewell S, Sauerbrei W, Collins G: Overinterpretation and misreporting of prognostic factor studies in oncology. Diagnostic and Prognostic Research, 2017; 1 Suppl. 1 (online): P39 (Methods for Evaluating Medical Tests and Biomarkers Birmingham, UK. 19–20 July 2016). :
  • Reese C, Weis J, Schmucker D, Mittag O: Practice guidelines for psychological interventions in the rehabilitation of patients with oncological disease Psycho-oncology, 2017; 26 (3): 60 (19th World Congress of Psycho-Oncology and Psychosocial Academy/Berlin/IPOS). :
  • Reese C, Weis J, Schmucker D, Mittag O: Praxisempfehlungen für psychologische Interventionen in der onkologischen Rehabilitation Beiträge zur 36. Jahrestagung des Arbeitskreises Klinische Psychologie in der Rehabilitation, 2017: 30-42 (36. Jahrestagung des Arbeitskreises Klinische Psychologie in der Rehabilitation BDP Psychologische Interventionen bei Verlusten und Verletzungen/Erkner/AK Klinische Psychologie in der Rehabilitation,), Arbeitskreis Klinische Psychologie in der Rehabilitation BDP (Hrsg).