Research Report for the year 2016

Scientific publications

Journal Articles:
  • Ahrens TD, Timme S, Ostendorp J, Bogatyreva L, Hoeppner J, Hopt UT, Hauschke D, Werner M, Lassmann S: Response of esophageal cancer cells to epigenetic inhibitors is mediated via altered thioredoxin activity. Lab Invest, 2016; 96: 307-316. : http://dx.doi.org/10.1038/labinvest.2015.148
  • Anderson AC, Jonas D, Huber I, Karygianni L, Wölber J, Hellwig E, Arweiler N, Vach K, Wittmer A, Al-Ahmad A: Enterococcus faecalis from Food, Clinical Specimens, and Oral Sites: Prevalence of Virulence Factors in Association with Biofilm Formation. Front Microbiol, 2016; 6 (online): 1534. : http://dx.doi.org/10.3389/fmicb.2015.01534
  • Aumann K, Niermann K, Asberger J, Wellner U, Bronsert P, Erbes T, Hauschke D, Stickeler E, Gitsch G, Kayser G, Werner M: Structured reporting ensures complete content and quick detection of essential data in pathology reports of oncological breast resection specimens. Breast Cancer Res Tr, 2016; 156: 495-500. : http://dx.doi.org/10.1007/s10549-016-3769-0
  • Chevalier N, Mueller M, Mougiakakos D, Ihorst G, Marks R, Schmitt-Graeff A, Veelken H: Analysis of dendritic cell subpopulations in follicular lymphoma with respect to the tumor immune microenvironment. Leukemia Lymphoma, 2016; 57: 2150-2160. : http://dx.doi.org/10.3109/10428194.2016.1143150
  • Frick M, Fischer J, Helbling A, Ruëff F, Wieczorek D, Ollert M, Pfützner W, Müller S, Huss-Marp J, Dorna B, Biedermann T, Lidholm J, Ruecker G, Bantleon F, Miehe M, Spillner E, Jakob T: Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. J Allergy Clin Immun, 2016; 138: 1663-1671. : http://dx.doi.org/10.1016/j.jaci.2016.04.024
  • Goebel U, Gebele N, Ebner W, Dettenkofer M, Bürkle H, Hauschke D, Schulz-Stübner S: Bacterial Contamination of the Anesthesia Workplace and Efficiency of Routine Cleaning Procedures: A Prospective Cohort Study. Anesth Analg, 2016; 122: 1444-1447. : http://dx.doi.org/10.1213/ANE.0000000000001220
  • Heiland DH *, Mader I *, Schlosser P, Pfeifer D, Carro MS, Lange T, Schwarzwald R, Vasilikos I, Urbach H, Weyerbrock A: Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme. Sci Rep-uk, 2016; 6 (online): 29052. : http://dx.doi.org/10.1038/srep29052
  • Hein S, Miernik A, Wilhelm K, Schlager D, Schoeb DS, Adams F, Vach W, Schoenthaler M: Endoscopically Determined Stone Clearance Predicts Disease Recurrence Within 5 Years After Retrograde Intrarenal Surgery. J Endourol, 2016; 30: 644-649. : http://dx.doi.org/10.1089/end.2016.0101
  • Hochholzer w, Amann M, Tito A, Younas I, Löffelhardt N, Riede F, Potocnik C, Stratz C, Hauschke D, Trenk D, Neumann F-J, Valina CM: Randomized Comparison of Different Thienopyridine Loading Strategies in Patients Undergoing Elective Coronary Intervention: The ExcelsiorLOAD Trial. Jacc-cardiovasc Inte, 2016; 9: 219-227. : http://dx.doi.org/10.1016/j.jcin.2015.10.036
  • Hoeppner J, Lordick F, Brunner T, Glatz T, Bronsert P, Röthling N, Schmoor C, Lorenz D, Ell C, Hopt UT, Siewert JR: ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286). Bmc Cancer, 2016; 16 (online): 503. : http://dx.doi.org/10.1186/s12885-016-2564-y
  • Kasenda B, Sauerbrei W, Royston P, Mercat A, Slutsky AS, Cook D, Guyatt GH, Brochard L, Richard J-CM, Stewart TE, Meade M, Briel M: Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS. Bmj Open, 2016; 6 (online): e011148. : http://dx.doi.org/10.1136/bmjopen-2016-011148
  • Lübbert M, Suciu S, Hagemeijer A, Rüter B, Platzbecker U, Giagounidis A, Selleslag D, Labar B, Germing U, Salih HR, Muus P, Pflüger K-H, Schaefer H-E, Bogatyreva L, AulC, de Witte T, Ganser A, Becker H, Huls G, van der Helm L, Vellenga E, Baron F, Marie J-P, Wijermans PW, on behalf of the EORTC Leukemia Group, the German MDS Study Grou: Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Group. Ann Hematol, 2016; 95: 191-199. : http://dx.doi.org/10.1007/s00277-015-2547-0
  • Lutz L, Fitzner IC, Ahrens T, Geißler AL, Makowiec F, Hopt UT, Bogatyreva L, Hauschke D, Werner M, Lassmann S: Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro. Am J Cancer Res, 2016; 6: 664-676.
  • Machado V, Gilsbach R, Das R, Schober A, Bogatyreva L, Hauschke D, Krieglstein K, Unsicker K, Spittau B: Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice. Cell Tissue Res, 2016; 365: 209-223. : http://dx.doi.org/10.1007/s00441-016-2406-x
  • Maier S, Perlov E, Graf E, Dieter E, Sobanski E, Rump M, Warnke A, Ebert D, Berger M, Matthies S, Philipsen A, Tebartz van Elst L: Discrete Global but No Focal Gray Matter Volume Reductions in Unmedicated Adult Patients with Attention-Deficit/Hyperactivity Disorder. Biol Psychiat, 2016; 80: 905-915. : http://dx.doi.org/10.1016/j.biopsych.2015.05.012
  • Maurer J, Grotejohann B, Jenkner C, Schneider C, Flury T, Tassoni A, Angele P, Fritz J, Albrecht D, Niemeyer P: A Registry for Evaluation of Efficiency and Safety of Surgical Treatment of Cartilage Defects: The German Cartilage Registry (KnorpelRegister DGOU). JMIR Research Protocols, 2016; 5 (online): e122. : http://dx.doi.org/10.2196/resprot.5895
  • Michalska M, Schultze-Seemann S, Bogatyreva L, Hauschke D, Wetterauer U, Wolf: In vitro and in vivo effects of a recombinant anti-PSMA immunotoxin in combination with docetaxel against prostate cancer. Oncotarget, 2016; 7 (16): 22531-22542. : http://dx.doi.org/10.18632/oncotarget.8001
  • Mueller KF, Meerpohl JJ, Briel M, Antes G, von Elm E, Lang B, Motschall E, Schwarzer G, Bassler D: Methods for detecting, quantifying, and adjusting for dissemination bias in meta-analysis are described. J Clin Epidemiol, 2016; 80: 25-33. : http://dx.doi.org/10.1016/j.jclinepi.2016.04.015
  • Reese C, Hübner P, Petrak F, Schmucker D, Weis J, Mittag O: Strukturen und Praxis der psychologischen Abteilungen in der onkologischen und diabetologischen Rehabilitation: Ergebnisse einer bundesweiten Befragung Rehabilitation, 2016; 55: 40-47.
  • Reinohl J, Psyrakis D, Kaier K, Kodirov S, Siepe M, Gutmann A, von Zur Muhlen C, Moser M, Ahrens I, Pache G, Zirlik A, Langer M, Beyersdorf F, Zehender M, Bode C, Blanke P: Aortic root volume is associated with contained rupture of the aortic annulus in balloon-expandable transcatheter aortic valve replacement. Catheter Cardio Inte, 2016; 87 (4): 807-817. : http://dx.doi.org/10.1002/ccd.26260
  • Stewardson AJ, Allignol A, Beyersmann J, Graves N, Schumacher M, Meyer R, Tacconelli E, De Angelis G, Farina C, Pezzoli F, Bertrand X, Gbaguidi-Haore H, Edgeworth J, Tosas O, Martinez JA, Ayala-Blanco MP, Pan A, Zoncada A, Marwick CA, Nathwani D, Seifert H, Hos N, Hagel S, Pletz M, Harbarth S, the TIMBER Study Group 18: The health and economic burden of bloodstream infections caused by antimicrobial-susceptible and non-susceptible Enterobacteriaceae and Staphylococcus aureus in European hospitals, 2010 and 2011: a multicentre retrospective cohort study. Eurosurveillance, 2016; 21 (online): 30319. : http://dx.doi.org/10.2807/1560-7917.ES.2016.21.33.30319
  • Taschner CA, Chapot R, Costalat V, Machi P, Courthéoux, Barreau X, Berge J, Pierot L, Kadziolka K, Jean B, Blanc, Biondi A, Brunel H, Gallas S, Berlis A, Herbreteau D, Berkefeld J, Urbach H, El Shikh S, Fiehler J, Desal H, Graf E, Bonafé A: GREAT—a randomized controlled trial comparing HydroSoft/HydroFrame and bare platinum coils for endovascular aneurysm treatment: procedural safety and core-lab-assessedangiographic results. Neuroradiology, 2016; 58: 777-786. : http://dx.doi.org/10.1007/s00234-016-1693-y
  • Tebartz van Elst L, Maier S, Klöppel S, Graf E, Killius C, Rump M, Sobanski E, Ebert D, Berger M, Warnke A, Matthies S, Perlov E, Philipsen A: The effect of methylphenidate intake on brain structure in adults with ADHD in a placebo-controlled randomized trial. J Psychiatr Neurosci, 2016; 41: 422-430. : https://dx.doi.org/10.1503%2Fjpn.150320
  • Woelber JP, Bremer K, Vach K, König D, Hellwig E, Ratka-Krüger P, Al-Ahmad A, Tennert C: An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study. Bmc Oral Health, 2016; 17 (online): 28. : http://dx.doi.org/10.1186/s12903-016-0257-1
Book Chapters:
  • Mittag O, Hartmann-Mittag D: Beratung und Begleitung von Menschen in der Lebensendphase In: Gieseke, Wiltrud & Nittel, Dieter (Hrsg.): Pädagogische Beratung über die Lebensspanne. Ein Handbuch Weinheim, Basel: Beltz Juventa, 2016; 401-409.
Short Communications:
  • Hauschke D, Schmoor C: Methodological aspects of the benefit assessment of medical interventions. Biometrical J, 2016; 58: 5-7. : http://dx.doi.org/10.1002/bimj.201500160
  • Lorenz J, Waldschmidt J, Wider D, Follo M, Ihorst G, Chatterjee M, May AM, Duyster J, Rosenwald A, Wäsch R, Zirlik K, Engelhardt M: From CLL to Multiple Myeloma - Spleen Tyrosine Kinase (SYK) influences multiple myeloma cell survival and migration. Brit J Haematol, 2016; 174: 985-989. : http://dx.doi.org/10.1111/bjh.13825
Other publications (type Sonstiges):
  • Woelber JP, Bremer K, Vach K, König D, Hellwig E, Ratka-Krüger P, Al-Ahmad A, Tennert C: Erratum to: An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study. Bmc Oral Health, 2016; 16: 109. : https://doi.org/10.1186/s12903-016-0304-y