Forschungsbericht für das Jahr 2016

Institut für Medizinische Biometrie und Statistik

Stefan-Meier-Strasse 26
79104 Freiburg
Tel: 0761 203 6662 Fax: 0761 203 6680
Email sec@imbi.uni-freiburg.de
http://www.imbi.uni-freiburg.de


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. M. Schumacher
  • Prof. Dr. J. Schulte Mönting
  • Arthur Allignol
  • Dr. G. Antes
  • Dr. J. Beyersmann
  • Dr. H. Binder
  • Dr. Anette Blümle
  • D. Booker
  • Dipl.-Stat. Anika Buchholz
  • Dr. A. Caputo
  • Dr. J. Carpenter
  • Dr. Erik von Elm
  • Dipl.-Math. C. Gall
  • Dr. T. Gerds
  • Dipl.-Stat. A. Gerlach
  • Dr. E. Graf
  • Prof. Dr. Dieter Hauschke
  • Dr. G. Ihorst
  • Dr. B. Lang
  • Dr. Jörg Meerpohl
  • Dipl.-Stat. M. Olschewski
  • Dipl.-Stat. Christine Porzelius
  • Dipl.-Math. G. Rücker
  • PD Dr. W. Sauerbrei
  • Dr. C. Schmoor
  • Dr. Christine Schmucker
  • Dipl.-Math.Oec. R. Schoop
  • Dr. G. Schwarzer
  • Dipl.-Math. P. Sekula
  • Dipl.-Stat. S. Stampf
  • PD Dr. A. Timmer
  • Robert Wolff
  • Dr. M. Wolkewitz
Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Biometrische Methodologie
  • Epidemiologische Studien
  • Klinische Studien
  • Multizentrische Therapiestudien

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Baier P, Ihorst G, Wolff-Vorbeck G, M. Hülld M, Hopta U, Deschler B: Independence and health related quality of life in 200 onco-geriatric surgical patients within 6 months of follow-up: Who is at risk to lose? Ejso-eur J Surg Onc, 2016; 42: 1890-1897. : http://dx.doi.org/10.1016/j.ejso.2016.07.013
  • Coenen VA, Jenkner C, Honey CR, Mädler B: Electrophysiologic Validation of Diffusion Tensor Imaging Tractography during Deep Brain Stimulation Surgery. Am J Neuroradiol, 2016; 37: 1470-1478. : http://dx.doi.org/10.3174/ajnr.A4753
  • Dettenkofer M, Humphreys H, Saenz H, Carlet J, Hanberger H, Ruef C, Widmer A, Wolkewitz M, Cookson B: Key priorities in the prevention and control of healthcare-associated infection: a survey of European and other international infection prevention experts. Infection, 2016; 44: 719-724. : https://dx.doi.org/10.1007/s15010-016-0904-0
  • Diem R, Molnar F, Beisse F, Gross N, Drüschler K, Heinrich SP, Joachimsen L, Rauer S, Pielen A, Sühs K-W, Linker RA, Huchzermeyer C, Albrecht P, Hassenstein A, Aktas O, Guthoff T, Tonagel F, Kernstock C, Hartmann K, Kümpfel T, Hein K, van Oterendorp C, Grotejohann B, Ihorst G, Maurer J, Müller M, Volkmann M, Wildemann B, Platten M, Wick W, Heesen C, Schiefer U, Wolf S, Lagrèze WA: Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial—study protocol. Bmj Open, 2016; 6 (online): e010956. : http://dx.doi.org/10.1136/bmjopen-2015-010956
  • Erbes T, Hirschfeld M, Waldeck S, Rücker G, Jäger M, Willmann L, Kammerer B, Mayer S, Gitsch G, Stickeler E: Hyperthermia-driven aberrations of secreted microRNAs in breast cancer in vitro. Int J Hyperther, 2016; 32 (6): 630-642. : http://dx.doi.org/10.3109/02656736.2016.1161832
  • Finke J, Schmoor C, Bertz H, Marks R, Wäsch R, Zeiser R, Hackanson B: Long-term follow-up of therapy-related myelodysplasia and AML patients treated with allogeneic hematopoietic cell transplantation. Bone Marrow Transpl, 2016; 51: 771-777. : http://dx.doi.org/10.1038/bmt.2015.338
  • Frick M, Fischer J, Helbling A, Ruëff F, Wieczorek D, Ollert M, Pfützner W, Müller S, Huss-Marp J, Dorna B, Biedermann T, Lidholm J, Ruecker G, Bantleon F, Miehe M, Spillner E, Jakob T: Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. J Allergy Clin Immun, 2016; 138: 1663-1671. : http://dx.doi.org/10.1016/j.jaci.2016.04.024
  • Illerhaus G, Kasenda B, Ihorst G, Egerer G, Lamprecht M, Keller U, Wolf H-H, Hirt C, Stilgenbauer S, Binder M, Hau P, Edinger M, Frickhofen N, Bentz M, Möhle R, Röth A, Pfreundschuh M, von Baumgarten L, Deckert M, Hader C, Fricker H, Valk E, Schorb E, Fritsch K, Finke J: High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma: a prospective, single-arm, phase 2 trial. Lancet Haematol, 2016; 3 (online): e388-e397. : http://dx.doi.org/10.1016/S2352-3026(16)30050-3
  • Kasenda B, Sauerbrei W, Royston P, Mercat A, Slutsky AS, Cook D, Guyatt GH, Brochard L, Richard J-CM, Stewart TE, Meade M, Briel M: Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS. Bmj Open, 2016; 6 (online): e011148. : http://dx.doi.org/10.1136/bmjopen-2016-011148
  • Lübbert M, Suciu S, Hagemeijer A, Rüter B, Platzbecker U, Giagounidis A, Selleslag D, Labar B, Germing U, Salih HR, Muus P, Pflüger K-H, Schaefer H-E, Bogatyreva L, AulC, de Witte T, Ganser A, Becker H, Huls G, van der Helm L, Vellenga E, Baron F, Marie J-P, Wijermans PW, on behalf of the EORTC Leukemia Group, the German MDS Study Grou: Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Group. Ann Hematol, 2016; 95: 191-199. : http://dx.doi.org/10.1007/s00277-015-2547-0
  • Machado V, Gilsbach R, Das R, Schober A, Bogatyreva L, Hauschke D, Krieglstein K, Unsicker K, Spittau B: Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice. Cell Tissue Res, 2016; 365: 209-223. : http://dx.doi.org/10.1007/s00441-016-2406-x
  • Maurer J, Grotejohann B, Jenkner C, Schneider C, Flury T, Tassoni A, Angele P, Fritz J, Albrecht D, Niemeyer P: A Registry for Evaluation of Efficiency and Safety of Surgical Treatment of Cartilage Defects: The German Cartilage Registry (KnorpelRegister DGOU). JMIR Research Protocols, 2016; 5 (online): e122. : http://dx.doi.org/10.2196/resprot.5895
  • Mueller KF, Meerpohl JJ, Briel M, Antes G, von Elm E, Lang B, Motschall E, Schwarzer G, Bassler D: Methods for detecting, quantifying, and adjusting for dissemination bias in meta-analysis are described. J Clin Epidemiol, 2016; 80: 25-33. : http://dx.doi.org/10.1016/j.jclinepi.2016.04.015
  • Schmid B, Fink K, Olschewski M, Richter S, Schwab T, Brunner M, Busch HJ: Accuracy and precision of transcardiopulmonary thermodilution in patients with cardiogenic shock. J Clin Monit Comput, 2016; 30: 849-856. : http://dx.doi.org/10.1007/s10877-015-9782-8
  • Schorb E, Finke J, Ferreri AJM, Ihorst G, Mikesch K, Kasenda B, Fritsch K, Fricker H, Burger E, Grishina O, Valk E, Zucca E, Illerhaus G: High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma—a randomized phase III trial (MATRix). Bmc Cancer, 2016; 16 (online): 282. : http://dx.doi.org/10.1186/s12885-016-2311-4
  • Schröder W, Sommer H, Gladstone BP, Foschi F, Hellman J, Evengard B, Tacconelli E: Gender differences in antibiotic prescribing in the community: a systematic review and meta-analysis. J Antimicrob Chemoth, 2016; 71: 1800-1806. : http://dx.doi.org/10.1093/jac/dkw054
  • Taschner CA, Chapot R, Costalat V, Machi P, Courthéoux, Barreau X, Berge J, Pierot L, Kadziolka K, Jean B, Blanc, Biondi A, Brunel H, Gallas S, Berlis A, Herbreteau D, Berkefeld J, Urbach H, El Shikh S, Fiehler J, Desal H, Graf E, Bonafé A: GREAT—a randomized controlled trial comparing HydroSoft/HydroFrame and bare platinum coils for endovascular aneurysm treatment: procedural safety and core-lab-assessedangiographic results. Neuroradiology, 2016; 58: 777-786. : http://dx.doi.org/10.1007/s00234-016-1693-y
  • Wirsum C, Glaser C, Gutenberger S, Keller B, Unger S, Voll RE, Vach W, Ness T, Warnatz K: Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency. J Clin Immunol, 2016; 36: 406-412. : http://dx.doi.org/10.​1007/​s10875-016-0264-7
  • Wolkewitz M, Cooper B, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P Barnett AG, Schumacher M: Multiple time scales in modeling the incidence of infections acquired in intensive care units. Bmc Med Res Methodol, 2016; 16 (online): 116. : http://dx.doi.org/10.1186/s12874-016-0199-y

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten