Forschungsbericht für das Jahr 2015

Institut für Medizinische Biometrie und Statistik

Stefan-Meier-Strasse 26
79104 Freiburg
Tel: 0761 203 6662 Fax: 0761 203 6680
Email sec@imbi.uni-freiburg.de
http://www.imbi.uni-freiburg.de


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. M. Schumacher
  • Prof. Dr. J. Schulte Mönting
  • Arthur Allignol
  • Dr. G. Antes
  • Dr. J. Beyersmann
  • Dr. H. Binder
  • Dr. Anette Blümle
  • D. Booker
  • Dipl.-Stat. Anika Buchholz
  • Dr. A. Caputo
  • Dr. J. Carpenter
  • Dr. Erik von Elm
  • Dipl.-Math. C. Gall
  • Dr. T. Gerds
  • Dipl.-Stat. A. Gerlach
  • Dr. E. Graf
  • Prof. Dr. Dieter Hauschke
  • Dr. G. Ihorst
  • Dr. B. Lang
  • Dr. Jörg Meerpohl
  • Dipl.-Stat. M. Olschewski
  • Dipl.-Stat. Christine Porzelius
  • Dipl.-Math. G. Rücker
  • PD Dr. W. Sauerbrei
  • Dr. C. Schmoor
  • Dr. Christine Schmucker
  • Dipl.-Math.Oec. R. Schoop
  • Dr. G. Schwarzer
  • Dipl.-Math. P. Sekula
  • Dipl.-Stat. S. Stampf
  • PD Dr. A. Timmer
  • Robert Wolff
  • Dr. M. Wolkewitz
Einträge in der Rubrik "Who is Who"

Forschungsschwerpunkte

  • Biometrische Methodologie
  • Epidemiologische Studien
  • Klinische Studien
  • Multizentrische Therapiestudien

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Arezzo A, Passera R, Salvai A, Arolfo S, Allaix ME, Schwarzer G, Morino M: Laparoscopy for rectal cancer is oncologically adequate: a systematic review and meta-analysis of the literature. Surg Endosc, 2015; 29: 334-348. : http://dx.doi.org/10.1007/s00464-014-3686-4
  • Bittermann G, Thönissen P, Poxleitner P, Zimmerer R, Vach K, Metzger MC: Microvascular transplants in head and neck reconstruction: 3D evaluation of volume loss. J Cranio Maxill Surg, 2015; 43: 1319-1324. : http://dx.doi.org/ doi:10.1016/j.jcms.2015.06.013
  • Bittermann G, Voss P, Duttenhoefer F, Zimmerer R, Vach K, Metzger MC: The validity of surgical clips as radiographic markers for the tumour resection cavity in head and neck cancer treatment. J Cranio Maxill Surg, 2015; 43: 758-762. : http://dx.doi.org/10.1016/j.jcms.2015.04.005
  • Callizo J, Feltgen N, Pantenburg S, Wolf A, Neubauer AS, Jurklies B, Wachter R, Schmoor C, Schumacher M, Junker B, Pielen A, for the European Assessment Group for Lysis in the Eye: Cardiovascular risk factors in central retinal artery occlusion: results of a prospective and standardized medical examination. Ophthalmology, 2015; 122: 1881-1888. : http://dx.doi.org/10.1016/j.ophtha.2015.05.044
  • Dersch R, Freitag MH, Schmidt S, Sommer H, Rauer S, Meerpohl JJ: Efficacy and safety of pharmacological treatments for acute Lyme neuroborreliosis – a systematic review. Eur J Neurol, 2015; 22: 1249-1259. : http://dx.doi.org/10.1111/ene.12744
  • Dersch R, Toews I, Sommer H, Rauer S, Meerpohl JJ: Methodological quality of guidelines for management of Lyme neuroborreliosis. Bmc Neurol, 2015; 15 (online): 242. : http://dx.doi.org/10.1186/s12883-015-0501-3
  • Dittrich S, Tuerk M, Haaker G, Greim V, Buchholz A, Burkhardt B, Fujak A, Trollmann R, Schmid A, Schroeder R: Cardiomyopathy in Duchenne Muscular Dystrophy: Current Value of Clinical, Electrophysiological and Imaging Findings in Children and Teenagers. Klin Padiatr, 2015; 227: 225-231. : http://dx.doi.org/10.1055/s-0034-1398689
  • Engelhardt M, Ihorst G, Landgren O, Pantic M, Reinhardt H, Waldschmidt J, May AM, Schumacher M, Kleber M, Wäsch R: Large registry analysis to accurately define second malignancy rates and risks in a well-characterized cohort of 744 consecutive multiple myeloma patients followed-up for 25 years. Haematologica, 2015; 100: 1340-1349. : http://dx.doi.org/10.3324/haematol.2015.127548
  • Jost WH, Benecke R, Hauschke D, Jankovic J, Kaƈovský P, Roggenkämper P, Simpson DM, Comella CL: Clinical and pharmacological properties of incobotulinumtoxinA and its use in neurological disorders. Drug Des Dev Ther, 2015; 9: 1913-1926. (download: http://dx.doi.org/10.2147/DDDT.S79193)
  • Lang R, Baumann P, Schmoor C, Odermatt EK, Wente MN, Jauch KW: A-Part Gel, an adhesion prophylaxis for abdominal surgery: a randomized controlled phase I-II safety study [NCT00646412]. Ann Surg Innov Res, 2015; 9 (online): 5. : http://dx.doi.org/10.1186/s13022-015-0014-1
  • Münch C, Dragoi D, Frey A-V, Thurig K, Lübbert M, Wäsch R, Bogatyreva L, Hauschke D, Lassmann S, Werner M, May AM: Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines. Leukemia Res, 2015; 39: 462-470. : http://dx.doi.org/10.1016/j.leukres.2015.01.007
  • Naegele M, Leppla L, Kiote-Schmidt C, Ihorst G, Rebafka A, Koller A, M. May AM, Hasemann M, Duyster J, Wäsch R, Engelhardt M: Trained clinical nurse specialists proficiently obtain bone marrow aspirates and trephine biopsies in a nearly painless procedure—a prospective evaluation study. Ann Hematol, 2015; 94: 1577-1584. (download: http://dx.doi.org/10.1007/s00277-015-2405-0)
  • Proksch S, Bittermann G, Vach K, Nitschke R, Tomakidi P, Hellwig E: hMSC-Derived VEGF Release Triggers the Chemoattraction of Alveolar Osteoblasts. Stem Cells, 2015; 33: 3114-3124. : http://dx.doi.org/10.1002/stem.2119
  • Sijare F, Geißler A-L, Fichter CD, Hergeth SP, Bogatyreva L, Hauschke D, Schneider R, Werner M, Lassmann S: Aurora B expression and histone variant H1.4S27 phosphorylation are no longer coordinated during metaphase in aneuploid colorectal carcinomas. Virchows Arch, 2015; 466 (5): 503-515. : http://dx.doi.org/10.1007/s00428-015-1727-6
  • Taschner C, Chapot R, Costalat V, Courthéoux P, Barreau X, Berge J, Pierot L, Kadziolka K, Jean B, Blanc R, Biondi A, Brunel H, Gallas S, Berlis A, Herbreteau D, Berkefeld J, Groden C, Urbach H, El Shikh S, Graf E, Bonafé A: GREAT—a randomized aneurysm trial. Design of a randomized controlled multicenter study comparing HydroSoft/HydroFrame and bare platinum coils for endovascular aneurysm treatment. Neuroradiology, 2015; 57: 599-604. : http://dx.doi.org/10.1007/s00234-015-1501-0
  • Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder SK, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, de Fontbrune FS, Na I-K, Penter L, Holtick U, Wolf D, Schuler E, Meyer E, Apostolova P, Bertz H, Marks R, Lübbert M, Wäsch R, Scheid C, Stölzel F, Ordemann R, Bug G, Kobbe G, Negrin R, Brune M, Spyridonidis A, Schmitt-Gräff A, van der Velden W, Huls G, Mielke S, Grigoleit GU, Kuball J, Flynn R, Ihorst G, Du J, Blazar BR, Arnold R, Kröger N, Passweg J, Halter J, Socié G, Beelen D, Peschel C, Neubauer A, Finke J, Duyster J, von Bubnoff N: Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey. Leukemia, 2015; 29: 2062-2068. : http://dx.doi.org/10.1038/leu.2015.212
Kurzbeiträge / short communications:
Sonstige Publikationen:
  • Winter A, Hilgers R-D, Hofestädt R, Hübner U, Knaup-Gregori P, Ose C, Schmoor C, Timmer A, Wege D: Good Medicine and Good Healthcare Demand Good Information (Systems). [Editorial]. Method Inform Med, 2015; 54: 385-387. : http://dx.doi.org/10.3414/ME15-05-1001

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten