Research Report for the year 1980-2015

Scientific publications

• Ahlert T, Sauerbrei W, Bastert G, Ruhland S, Bartik B, Simiantonaki N, Schumacher J, Häcker B, Schumacher M, Schirrmacher V: Tumor-cell number and viability as quality and efficacy parameters of autologous virus-modified cancer vaccines in patients with breast or ovarian cancer. Journal of Clinical Oncology, 1997; 15: 1354-1366.
• Allignol A, Beyersmann J, Schumacher M: mvna: An R Package for the Nelson–Aalen Estimator in Multistate Models. R News, 2008; 8: 48-50. : http://CRAN.R-project.org/doc/Rnews
• Allignol A, Schumacher M, Beyersmann J: A note on variance estimation of the Aalen-Johansen estimator of the cumulative incidence function in competing risks, with a view towards left-truncated data. Biometrical J, 2010; 52: 126-137. : http://dx.doi.org/10.1002/bimj.200900039
• Allignol A, Schumacher M, Beyersmann J: Estimating summary functionals in multistate models with an application to hospital infection data. Computation Stat, 2011; 26: 181-197. : http://dx.doi.org/10.1007/s00180-010-0200-x
• Allignol A, Schumacher M, Wanner C, Drechsler C, Beyersmann J: Understanding competing risks: a simulation point of view. Bmc Med Res Methodol, 2011; 11 (online): 86. (download: http://dx.doi.org/10.1186/1471-2288-11-86)
• Altman DG, Lausen B, Sauerbrei W, Schumacher M: Danger of using "optimal" cutpoints in the evaluation of prognostic factors. Journal of the National Cancer Institute, 1994; 86: 829-835.
• Antes G, Augustin N, Beyersmann J, Caputo A, Falck-Ytter Y, Gerds T, Gerlach A, Graf E, Holländer N, Ihorst G, Lang B, Meier-Hirmer C, Musio M, Olschewski M, Roßner R, Sauerbrei W, Schlingmann J, Schmoor C, Schulgen G, Schulte Mönting J, Schwarzer G, Schumacher M: Freiburger Beiträge zur Biometrie und Klinischen Epidemiologie. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2004; 35: 74-122.
• Antes G, Dreier G, Hasselblatt H, Blümle A, Schumacher M: Register für klinische Studien - Einführung in das Thema und Hintergründe. Clinical trials registers - Introduction to the topic and backgrounds. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2009; 52: 459-462. : http://dx.doi.org/10.1007/s00103-009-0832-6
• Augustin N, Sauerbrei W, Schumacher M: The practical utility of incorporating model selection uncertainty into prognostic models for survival data. Statistical Modelling, 2005; 5: 95-118.
• Augustin NH, Musio M, Wilpert von K, Kublin E, Wood SN, Schumacher M: Modeling spatiotemporal forest health monitoring data. J Am Stat Assoc, 2009; 104: 899-911. : http://dx.doi.org/10.1198/jasa.2009.ap07058
• Beyersmann J, Dettenkofer M, Bertz H, Schumacher M: A competing risks analysis of bloodstream infection after stem-cell transplantation using subdistribution hazards and cause-specific hazards. Stat Med, 2007; 26: 5360-5369.
• Beyersmann J, Gastmeier P, Grundmann H, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infection. Infect Cont Hosp Ep, 2006; 27: 493-499.
• Beyersmann J, Gastmeier P, Grundmann H, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Transmission-associated nosocomial infections: Prolongation of intensive care unit stay and risk factor analysis using multistate models: Am J Infect Control, 2008; 36: 98-103.
• Beyersmann J, Gastmeier P, Schumacher M: Incidence in ICU populations: how to measure and report it? Intens Care Med, 2014; 40: 871-876. : http://dx.doi.org/10.1007/s00134-014-3279-7
• Beyersmann J, Gastmeier P, Wolkewitz M, Schumacher M: An easy mathematical proof showed that time-dependent bias inevitably leads to biased effect estimation. J Clin Epidemiol, 2008; 61: 1216-1221. : http://dx.doi.org/10.1016/j.jclinepi.2008.02.008
• Beyersmann J, Kneib T, Schumacher M, Gastmeier P: Nosocomial infection, length of stay, and time‐dependent bias. Infect Cont Hosp Ep, 2009; 30: 273-276. : http://dx.doi.org/10.1086/596020
• Beyersmann J, Latouche A, Buchholz A, Schumacher M: Simulating competing risks data in survival analysis. Stat Med, 2009; 8: 956-971. : http://dx.doi.org/10.1002/sim.3516
• Beyersmann J, Schumacher M: Time-dependent covariates in the proportional subdistribution hazards model for competing risks. Biostatistics, 2008; 9: 765-776. : http://dx.doi.org/10.1093/biostatistics/kxn009
• Beyersmann J, Schumacher M: A note on nonparametric quantile inference for competing risks and more complex multistate models. Biometrika, 2008; 95: 1006-1008. : http://dx.doi.org/10.1093/biomet/asn044
• Beyersmann J, Wolkewitz M, Allignol A, Grambauer N, Schumacher M: Application of multistate models in hospital epidemiology: Advances and challenges. Biometrical J, 2011; 53: 332-350. : http://dx.doi.org/10.1002/bimj.201000146
• Beyersmann J, Wolkewitz M, Schumacher M: The impact of time-dependent bias in proportional hazards modelling. Stat Med, 2008; 27: 6439-6454. : http://dx.doi.org/10.1002/sim.3437
• Bierbaum S, Konigsfeld N, Besazza N, Blessing K, Rücker G, Kontny U, Berner R, Schumacher M, Forster J, Falcone V, van de Sand C, Essig A, Huzly D, Rohde G, Neumann-Haefelin D, Panning M: Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study). Eur J Clin Microbiol, 2012; 31 (10): 2851-2861. : http://dx.doi.org/10.1007/s10096-012-1639-1
• Binder H, Allignol A, Schumacher M, Beyersmann J: Boosting for high-dimensional time-to-event data with competing risks. Bioinformatics, 2009; 25: 890-896. : http://dx.doi.org/10.1093/bioinformatics/btp088
• Binder H, Benner A, Bullinger L, Schumacher M: Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures. Stat Med, 2013; 32: 1778-1791. : http://dx.doi.org/10.1002/sim.5490
• Binder H, Müller T, Schwender H, Golka K, Steffens M, Hengstler JG, Ickstadt K, Schumacher M: Cluster-Localized Sparse Logistic Regression for SNP Data. Stat Appl Genet Mol, 2012; 11 (online). : http://dx.doi.org/10.1515/1544-6115.1694
• Binder H, Porzelius C, Schumacher M: An overview of techniques for linking high-dimensional molecular data to time-to-event endpoints by risk prediction models. Biometrical J, 2011; 53: 170-189. : http://dx.doi.org/10.1002/bimj.201000152
• Binder H, Schumacher M: Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models. Bmc Bioinformatics, 2008; 9: 10-19.
• Binder H, Schumacher M: Adapting prediction error estimates for biased complexity selection in high-dimensional bootstrap samples. Statistical Applications in Genetics and Molecular Biology, 2008; 7 (1) (online): Article 12. : http://www.bepress.com/sagmb/vol7/iss1/art12
• Binder H, Schumacher M: Comment on ‘network-constrained regularization and variable selection for analysis of genomic data’. Bioinformatics, 2008; 24: 2566-2568. : http://dx.doi.org/10.1093/bioinformatics/btn412
• Binder H, Schumacher M: Incorporating pathway information into boosting estimation of high-dimensional risk prediction models. Bmc Bioinformatics, 2009; 10 (1) (online): 18. : http://dx.doi.org/10.1186/1471-2105-10-18
• Binder N, Schumacher M: Missing information caused by death leads to bias in relative risk estimates. J Clin Epidemiol, 2014; 67: 1111-1120. : http://dx.doi.org/10.1016/j.jclinepi.2014.05.010
• Blümle A, Antes G, Schumacher M, Just H, von Elm E: Clinical research projects at a German medical faculty: follow-up from ethical approval to publication and citation by others J Med Ethics, 2008; 34 (online): e20. : http://dx.doi.org/10.1136/jme.2008.024521
• Blümle A, Meerpohl JJ, Rücker G, Antes G, Schumacher M, von Elm E: Reporting of eligibility criteria of randomised trials: cohort study comparing trial protocols with subsequent articles. Brit Med J, 2011; 342 (online): d1828 . : http://dx.doi.org/10.1136/bmj.d1828
• Blümle A, Meerpohl JJ, Schumacher M, von Elm E: Fate of clinical research studies after ethical approval – follow-up of study protocols until publication. Plos One, 2014; 9 (online): e87184. : http://dx.doi.org/10.1371/journal.pone.0087184
• Bohlius J, Schmidlin K, Brillant C, Schwarzer G, Trelle S, Seidenfeld J, Zwahlen M, Clarke M, Weingart O, Kluge S, Piper M, Rades D, Steensma DP, Djulbegovick B, Fey MF, Ray-Coquard I, Machtay M, Moebus V, Thomas G, Untch M, Schumacher M, Egger M, Engert A: Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials. Lancet, 2009; 373: 1532-1542. : http://dx.doi.org/10.1016/S0140-6736(09)60502-X
• Bohlius J, Schmidlin K, Brillant C, Schwarzer G, Trelle S, Seidenfeld J, Zwahlen M, Clarke MJ, Weingart O, Kluge S, Piper M, Napoli M, Rades D, Steensma D, Djulbegovic B, Fey MF, Ray-Coquard I, Moebus V, Thomas G, Untch M, Schumacher M, Egger M, Engert A: Erythropoietin or Darbepoetin for patients with cancer - meta-analysis based on individual patient data Cochrane Db Syst Rev, 2009; 3 (online): CD007303. : http://dx.doi.org/10.1002/14651858.CD007303.pub2
• Bojar H, Bastert G, Huebner K, Schumacher M, Schmoor C, Sauerbrei W: Prognostic Factors for node negative breast cancer patients. J Cancer Res Clin, 1990; 116: 42.
• Brugger W, Dierkesmann R, Toomes H, Engelhardt R, Hasse J, Pressler K, Kollmannsberger C, Schumacher M, Frommhold H, Bamberg M, Kanz L for the Limited-Disease, Lung Cancer Study Group: Multicenter randomized phase III study evaluating the role of high-dose chemotherapy and peripheral blood progenitor cell support in patients with limited-stage small-cell lung cancer. Onkologie, 1998; 21 Supplement 2: 12-14.
• Bühlmann P, Gertheiss J, Hieke S, Kneib T, Ma S, Schumacher M, Tutz G, Wang C-Y, Wang Z, Ziegler A: Discussion of “The Evolution of Boosting Algorithms” and “Extending Statistical Boosting”. Method Inform Med, 2014; 53: 436-445. : http://dx.doi.org/10.3414/13100122
• Callizo J, Feltgen N, Pantenburg S, Wolf A, Neubauer AS, Jurklies B, Wachter R, Schmoor C, Schumacher M, Junker B, Pielen A, for the European Assessment Group for Lysis in the Eye: Cardiovascular risk factors in central retinal artery occlusion: results of a prospective and standardized medical examination. Ophthalmology, 2015; 122: 1881-1888. : http://dx.doi.org/10.1016/j.ophtha.2015.05.044
• Colleoni M, Litman HJ, Castiglione-Gertsch M, Sauerbrei W, Gelber RD, Bonetti M, Coates AS, Schumacher M, Bastert G, Rudenstam C-M, Schmoor C, Lindtner J, Collins J, Thürlimann B, Holmberg SB, Crivellari D, Beyerle C, Neumann RLA, Goldhirsch A for the International Breast Cancer Study Group, the German Breast Cancer Study Group: Duration of adjuvant chemotherapy for breast cancer: a joint analysis of two randomised trials investigating three versus six courses of CMF. Brit J Cancer, 2002; 86 (11): 1705-1714.
• de Haes H, Olschewski M, Kaufmann M, Schumacher M, Jonat W, Sauerbrei W: Quality of life in Goserelin-treated versus Cyclophosphamide + Methotrexate + Fluorouracil-treated premenopausal and perimenopausal patients with node-positive, early breast cancer: The Zoladex Early Breast Cancer Research Association Trialists Group. J Clin Oncol, 2003; 21: 4510-4516.
• Dettenkofer M, Seegers S, Antes G, Motschall E, Schumacher M, Daschner FD: Does the architecture of hospital facilities influence nosocomial infection rates? A systematic review. Infect Cont Hosp Ep, 2004; 25 (1): 21-25.
• Dettenkofer M, Seegers S, Antes G, Motschall E, Schumacher M, Daschner FD: Does the architecture of hospital facilities influence nosocomial infection rates? A systematic review. Infect Cont Hosp Ep, 2004; 25: 21-25.
• Di Termini S, Hieke S, Schumacher M, Beyersmann J: Nonparametric inference for the cumulative incidence function of a competing risk, with an emphasis on confidence bands in the presence of left-truncation. Biometrical J, 2012; 54: 568-578. : http://dx.doi.org/10.1002/bimj.201100161
• Doerken S, Mockenhaupt M, Schumacher M, Sekula P: Assessment of the “Case-Chaos” design as an adjunct to the case-control design. Am J Epidemiol, 2014; 179: 775-780. : http://dx.doi.org/10.1093/aje/kwt310
• Dreier G, Hasselblatt H, Antes G, Schumacher M: Das Deutsche Register Klinischer Studien: Begründung, technische und inhaltliche Aspekte, internationale Einbindung. Bundesgesundheitsblatt, 2009; 52: 463-468. : http://dx.doi.org/10.1007/s00103-009-0833-5
• Ehlken B, Ihorst G, Lippert B, Rohwedder A, Petersen G, Schumacher M, Forster J, and for the PRIDE Study Group: Economic impact of community-acquired and nosocomial lower respiratory tract infections in young children in Germany. Eur J Pediatr, 2005; 1: 1432-1076.
• Eiermann W, Graf E, Ataseven B, Conrad B, Hilfrich J, Massinger-Biebl H, Vescia S, Loibl S, von Minckwitz G, Schumacher M, Kaufmannh M, and for the German Adjuvant Breast Cancer Group: Dose-intensified epirubicin versus standard-dose epirubicin/cyclophosphamide followed by CMF in breast cancer patients with 10 or more positive lymph nodes: Results of a randomised trial (GABG-IV E-93) – The German Adjuvant Breast Cancer Groupstar. Eur J Cancer, 2010; 46: 84-94. : http://dx.doi.org/10.1016/j.ejca.2009.10.001
• Els T, Klisch J, Orszagh M, Hetzel A, Schulte Mönting J, Schumacher M, Lücking CH: Hyperglycemia in patients with focal cerebral ischemia after intravenous thrombolysis: influence on clinical outcome and infarct size. Cerebrovasc Dis, 2002; 13 (2): 89-94.
• Engelhardt M, Ihorst G, Landgren O, Pantic M, Reinhardt H, Waldschmidt J, May AM, Schumacher M, Kleber M, Wäsch R: Large registry analysis to accurately define second malignancy rates and risks in a well-characterized cohort of 744 consecutive multiple myeloma patients followed-up for 25 years. Haematologica, 2015; 100: 1340-1349. : http://dx.doi.org/10.3324/haematol.2015.127548
• Feuerstein TJ, Roßner R, Schumacher M: How to express an effect mean as percentage of a control mean? Journal of Pharmacological and Toxicological Methods, 1997; 37: 187-190.
• Fogelman I, Blake GM, Palmer M, Sauerbrei W, Schumacher M, Serin D, Stewart A, Wilpshaar W: Bone mineral density in premenopasual women treated for node-positive early breast cancer with 2 years of goserelin or 6 months of cyclophosphamide, methotrexate and 5-fluorouracil (CMF). Osteoporosis Int, 2003; 14: 1001-1006.
• Forster J, Ihorst G, Rieger CHL, Stephan V, Frank H-D, Gurth H, Berner R, Rohwedder A, Werchau H, Schumacher M, Tsai T, Petersen G: Prospective population-based study of viral lower respiratory tract infections in children under 3 years of age (the PRID.DE study). Eur J Pediatr, 2004; 163: 709-716.
• Gastmeier P, Bräuer H, Hauer T, Schumacher M, Daschner F, Rüden H: How many nosocomial infections are missed if identification is restricted to patients with either microbiology reports or antibiotic administration? Infection Control and Hospital Epidemiology 20, 124-127, 1999; 20: 124-127.
• Gastmeier P, Kampf G, Hauer T, Schlingmann J, Schumacher M, Daschner F, Rüden H: Experience with two validation methods in a prevalence survey on nosocomial infections. Infection Control and Hospital Epidemiology, 1998; 19: 668-673.
• Gastmeier P, Kampf G, Wischnewski N, Hauer T, Schulgen G, Schumacher M, Daschner F, Rüden H: Prevalence of nosocomial infections in representative German hospitals. Journal of Hospital Infection, 1998; 38: 37-49.
• Gastmeier P, Kampf G, Wischnewski N, Schumacher M, Daschner F, Rüden H: Importance of the surveillance method: National prevalence studies on nosocomial infections and the limits of comparison. Infection Control and Hospital Epidemiology, 1998; 19: 661-667.
• Gastmeier P, Schumacher M, Daschner F, Rüden H: An analysis of two prevalence surveys of nosocomial infection in German intensive care units Journal of Hospital Infection, 1997; 35: 97-105.
• Gastmeier P, Sohr D, Forster D, Schulgen G, Schumacher M, Daschner F, Rüden H: Identifying outliers of antibiotic usage in prevalence studies on nosocomial infections Infect Cont Hosp Ep, 2000; 21: 324-328.
• Gastmeier P, Weist K, Schlingmann J, Schumacher M, Daschner F: Nosokomiale Infektionen in Deutschland - Erfassung und Prävention. Harnweginfektionen in deutschen Krankenhäusern und die Bedeutung der Harnwegkatheter. Der Urologe, 1997; 37: 360-365.
• Gastmeier P, Wischnewski N, Kampf G, Schumacher M, Daschner F, Rüden H: NIDEP - Studie, Teil 1: Wo steht die eigene Klinik? Klinikarzt, 1997; 26: 19-23.
• Gatzemeier W, Schumacher M, Schauer A, Sauer R, Rauschecker HF: Therapie des Kleinen Mammakarzinoms - flächendeckende Umsetzung der brusterhaltenden Behandlung in der BRD. 8-Jahres-Ergebnisse. Langenbecks Archiv für Chirurgie, 1997; Supplement II: 1212-1214.
• Genin E, Chen D-P, Hung S-I, Sekula P, Schumacher M, Chang P-Y, Tsai S-H, Wu T-L, Bellón T, Tamouza R, Fortier C, Toubert A, Charron D, Hovnanian A, Wolkenstein P, Chung W-H, Mockenhaupt M, Roujeau J-C: HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis. Pharmacogenomics J, 2014; 14: 281-288. : http://dx.doi.org/10.1038/tpj.2013.40
• Genin E, Schumacher M, Roujeau J-C, Naldi L, Liss Y, Kazma R, Sekula P, Hovnanian A, Mockenhaupt M: Genome-Wide Association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe. Orphanet J Rare Dis, 2011; 6 (online): 52. : http://dx.doi.org/10.1186/1750-1172-6-52
• Gerds TA, Cai T, Schumacher M: The performance of risk prediction models. Biometrical J, 2008; 50: 457-479.
• Gerds TA, Kattan MW, Schumacher M, Yu C: Estimating a time-dependent concordance index for survival prediction models with covariate dependent censoring. Stat Med, 2013; 32: 2173-2184. : http://dx.doi.org/10.1002/sim.5681
• Gerds TA, Schumacher M: On functional misspecification of covariates in the Cox regression model. Biometrika, 2001; 88 (2): 572-580.
• Gerds TA, Schumacher M: Consistent Estimation of the Expected Brier Score in General Survival Models with Right-Censored Event Times. Biometrical J, 2006; 48: 1029-1040.
• Gerds TA, Schumacher M: Efron-type measures of prediction error for survival analysis. Biometrics, 2007; 63: 1283-1287.
• Gerlinger C, Edler L, Friede T, Kieser M, Nakas CT, Schumacher M, Seldrup J, Victor N: Considerations on what constitutes a ‘qualified statistician’ in regulatory guidelines. Stat Med, 2012; 31: 1303-1305. : http://dx.doi.org/10.1002/sim.4345
• Graf E, Schmoor C, Sauerbrei W, Schumacher M: Assessment and comparison of prognostic classification schemes for survival data. Statistics in Medicine, 1999; 18: 2529-2545.
• Graf E, Schumacher M: An investigation on measures of explained variation in survival analysis. The Statistician, 1995; 44: 497-507.
• Grambauer N, Schumacher M, Beyersmann J: Proportional subdistribution hazards modeling offers a summary analysis, even if misspecified. Stat Med, 2010; 29: 885-895. : http://dx.doi.org/10.1002/sim.3786
• Grambauer N, Schumacher M, Dettenkofer M, Beyersmann J: Incidence densities in a competing events analysis. Am J Epidemiol, 2010; 172: 1077-1084. : http://dx.doi.org/10.1093/aje/kwq246
• Graw F, Gerds TA, Schumacher M: On pseudo-values for regression analysis in competing risks models. Lifetime Data Anal, 2009; 15: 241-255.
• Grüger J, Kay R, Schumacher M: The validity of inferences based on incomplete observations in disease state models. Biometrics, 1991; 40: 595-605.
• Grundmann H, Bärwolff S, Tami A, Behnke M, Schwab F, Geffers C, Halle E, Göbel UB, Schiller R, Jonas D, Klare I, Weist K, Witte W, Beck-Beilecke K, Schumacher M, Rüden H, Gastmeier P: How many infections are caused by patient-to-patient transmission in intensive care units? Crit Care Med, 2005; 33: 946-951.
• Hasselblatt H, Dreier G, Antes G, Schumacher M: The German Clinical Trials Register: challenges and chances of implementing a bilingual registry. J Evid Based Med, 2009; 2 (1): 36-40. : http://dx.doi.org/10.1111/j.1756-5391.2009.01001.x
• Hauer T, Gastmeier P, Schulgen G, Schumacher M, Rüden H, Daschner F: Mikrobiologische Diagnostik, Antibiotikaprophylaxe und Antibiotikatherapie - eine Standortbestimmung in deutschen Kliniken Medizinische Klinik, 1996; 91: 681-686.
• Hauer T, Huzly D, Gastmeier P, Schlingmann J, Schumacher M, Rüden H, Daschner F: Krankenhausinfektion in Gynäkologie und Geburtshilfe. Geburtshilfe und Frauenheilkunde, 1996; 56: 546-549.
• Henke M, Sindlinger F, Ikenberg H, Gerds T, Schumacher M: Blood hemoglobin level and treatment outcome of early breast cancer. Strahlenther Onkol, 2004; 180: 45-51.
• Hieke S, Bertz H, Dettenkofer M, Schumacher M, Beyersmann J: Initially fewer bloodstream infections for allogeneic vs. autologous stem-cell transplants in neutropenic patients. Epidemiol Infect, 2013; 141: 158-164. : http://dx.doi.org/10.1017/S0950268812000283
• Hieke S, Binder H, Nieters A, Schumacher M: minPtest: a resampling based gene region-level testing procedure for genetic case-control studies. Computation Stat, 2014; 29: 51-63. : http://dx.doi.org/10.1007/s00180-012-0391-4
• Hieke S, Kleber M, König C, Engelhardt M, Schumacher M: Conditional Survival: A Useful Concept to Provide Information on How Prognosis Evolves over Time. Clin Cancer Res, 2015; 21: 1530-1536. : http://dx.doi.org/10.1158/1078-0432.CCR-14-2154
• Holländer N, Rzany B, Mockenhaupt M, Schöpf E, Schumacher M: Statistische Ansätze zur Beurteilung seltener Arzneimittelrisiken in einer Fallstudie. Informatik, Biometrie und Epidemiologie in Medizin und Biolo, 1995; 26: 154-165.
• Holländer N, Sauerbrei W, Schumacher M: Confidence intervals for the effect of a prognostic factor after selection of an 'optimal' cutpoint. Stat Med, 2004; 23: 1701-1713.
• Holländer N, Schumacher M: On the problem of using 'optimal' cutpoints in the assessment of quantitative prognostic factors. Onkologie, 2001; 24: 194-199.
• Holländer N, Schumacher M: Estimating the functional form of a continuous covariate's effect on survival time. Comput Stat Data An, 2006; 50: 1131-1151.
• Holtbrügge W, Schumacher M: A comparison of regrression models for the analysis of ordered categorial data. J Appl Stat, 1991; 40: 249-259.
• Ihorst G, Forster J, Petersen G, Schumacher M: Determination of the population size in an epidemiological study with children. Method Inform Med, 2004; 43: 479-482.
• Ihorst G, Forster J, Petersen G, Werchau H, Rohwedder A, Schumacher M: The use of imperfect diagnostic tests had an impact on prevalence estimation. J Clin Epidemiol, 2007; 60: 902-910.
• Ihorst G, Frischer T, Horak F, Schumacher M, Kopp M, Forster J, Mattes J, Kuehr J: Long- and medium-term ozone effects on lung growth including a broad spectrum of exposure. Eur Respir J, 2004; 23: 292-299.
• Jander N, Sommer H, Pingpoh C, Kienzle R-P, Martin G, Zeh W, Pache G, Siepe M, Beyersdorf F, Schumacher M, Neumann F-J, Minners J: The porcine valve type predicts obstructive thrombosis beyond the first three postoperative months in bioprostheses in the aortic position. Int J Cardiol, 2015; 199: 90-95. : http://dx.doi.org/10.1016/j.ijcard.2015.07.022
• Jena S, Antes G, Dreier G, Schumacher M: Transparenz bei Arzneimittel- und anderen klinischen Studien – kein gelöstes Problem! Deutsche Zeitschrift für Klinische Forschung, 2011; 1: 58-62.
• Jonat W, Kaufmann M, Sauerbrei W, Blamey R, Cuzick J, Namer M, Fogelman I, de Haes JC, de Matteis A, Stewart A, Eiermann W, Szakolczai I, Palmer M, Schumacher M, Geberth M, Lisboa B: Goserelin versus Cyclophosphamide, Methotrexate, and Fluorouracil as adjuvant therapy in premenopausal patients with node-positive breast cancer: The Zoladex Early Breast Cancer Research Association Study. J Clin Oncol, 2002; 20 (24): 4628-4635.
• Just H, Drexler H, Taylor SH, Diegrist J, Schulgen G, Schumacher M, for the CADS study group: Captopril versus digoxin in patients with coronary artery disease and mild heart failure. A Prospective, double-blind, placebo-controlled multicenter study. Herz, 1993; 18: 436-443.
• Kaier K, Wilson C, Chalkley M, Davey PG, Suetens C, Grundmann H, de Kraker M, Schumacher M, Wolkewitz M, Frank U: Health and economic impacts of antibiotic resistance in European hospitals – Outlook on the BURDEN project. Infection, 2008; 36: 492-494. : http://dx.doi.org/10.1007/s15010-008-7453-0
• Kaier K, Wilson C, Hulscher M, Wollersheim H, Huis A, Borg M, Scicluna E, Lambert M-L, Palomar M, Tacconelli E, De Angelis G, Schumacher M, Wolkewitz M, Kleissle E-M, Frank U: Implementing strategic bundles for infection prevention and management. Infection, 2012; 40: 225-228. : http://dx.doi.org/10.1007/s15010-011-0186-5
• Kampf G, Gastmeier P, Wischnewski N, Schlingmann J, Schumacher M: Analysis of risk factors for nosocomial infections - results from the first national prevalence survey in Germany (NIDEP-study, part 1). Journal of Hospital Infection, 1997; 37: 103-112.
• Kampf G, Wischnewski N, Schulgen G, Schumacher M, Daschner F: Prevalence and risk factors for nosocomial lower respiratory tract infections in German hospitals. Journal of Clinical Epidemiology, 1998; 51: 495-502.
• Kappstein I, Schulgen G, Beyer U, Schumacher M, Daschner FD: Prolongation of hospital stay and extra costs due to ventilator-associated pneumonia in an intensive care unit. European Journal of Clinical Microbiology & Infectious Diseases, 1992; 11: 504-508.
• Kappstein I, Schulgen G, Fraedrich G, Schlosser V, Schumacher M, Daschner F D: Added hospital stay due to wound infections following cardiac surgery. The Thoracic and Cardiovasvular Surgeon, 1992; 40: 148-151.
• Kappstein I, Schulgen G, Richtmann R, Farthmann EH, Schlosser V, Geiger K, Just H, Schumacher M, Daschner F: Verlängerung der Krnakenhausverweildauer durch nosokomiale Pneumonie und Wundinfektion. Deutsche Medizinische Wochenzeitschrift, 1992; 116: 281-287.
• Kaufmann M, Graf E, Jonat W, Eiermann W, Geberth M, Albert U-S, Gademann G, Conrad B, Stahl K, Minckwitz von G, Schumacher M: Tamoxifen versus control after adjuvant, risk-adapted chemotherapy in postmenopausal, receptor-negative patients with breast cancer: A randomized trial (GABG-IV D-93) - The German Adjuvant Breast Cancer Group. J Clin Oncol, 2005; 23: 7842-7848.
• Kaufmann M, Graf E, Jonat W, Eiermann W, Vescia S, Geberth M, Conrad B, Gademann G, Albert U-S, Loibl S, von Minckwitz G, Schumacher M: A randomised trial of goserelin versus control after adjuvant, risk-adapted chemotherapy in premenopausal patients with primary breast cancer – GABG-IV B-93. Eur J Cancer, 2007; 43: 2351-2358.
• Kaufmann M, Jonat W, Blamey R, Cuzick J, Namer M, Fogelman I, de Haes JC, Schumacher M, Sauerbrei W on behalf of the Zoladex Early Breast Cancer Research Association (ZEBRA) Trialists' Group: Survival analyses from the ZEBRA study: goserelin (Zoladex TM) versus CMF in premenopausal women with node-positive breast cancer. Eur J Cancer, 2003; 39: 1711-1717.
• Kleber, M, Hieke, S, Koch, B, Ihorst, G, Wasch, R, Moreau, P, Schumacher, M, Engelhardt, M: Conditional survival (CS) analysis in a large cohort of 816 multiple myeloma (MM) patients (pts). Onkologie, 2013; 36 Suppl. 7: 170.
• Knapstein PG, Beck T, Schumacher M, Kreienberg, R: Multizentrische randomisierte Phase III-Studie zur adjuvanten Therapie des operablen Cervix-carcinoms-kooperative Studie der AGP. Der Frauenarzt, 1994; 35: 9.
• Kröger N, Milde-Langosch K, Riethdorf S, Schmoor C, Schumacher M, Zander AR, Löning T: Prognostic and predictive effects of immunohistochemical factors in high-risk primary breast cancer patients. Clin Cancer Res, 2006; 12: 159-168.
• Kübler J, Schumacher M: Survival time models for analysing drug combination treatments. Stat Med, 1990; 9: 1527-1539.
• Lambert M-L, Suetens C, Savey A, Palomar M, Hiesmayr M, Morales I, Agodi A, Frank U, Mertens K, Schumacher M, Wolkewitz M: Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect Dis, 2011; 11: 30-38. : http://dx.doi.org/10.1016/S1473-3099(10)70258-9
• Lausen B, Hothorn T, Bretz F, Schumacher M: Assessment of optimal selected prognostic factors. Biometrical J, 2004; 46: 364-374.
• Lausen B, Lerche R, Schumacher M: Maximally selected rank statistics for dose-response problems. Biometrical J, 2002; 44 (2): 131-147.
• Lausen B, Schumacher M: Maximally selected rank statistics. Biometrics, 1992; 48: 73-85.
• Leisser C, Kaufmann TA, Feltgen N, Schumacher M, Schmoor C, Meckel S: Distribution of internal carotid artery plaque locations among patients with central retinal artery occlusion in the Eagle study population. Graef Arch Clin Exp, 2015; 253 (8): 1227-1230. : http://dx.doi.org/10.1007/s00417-014-2804-2
• Lonjou C, Borot N, Sekula P, Ledger N, Thomas L, Halevy S, Naldi L, Bouwes-Bavinck J-N, Sidoroff A, de Toma C, Schumacher M, Roujeau J-C, Hovnanian A, Mockenhaupt M for the RegiSCAR study: A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs. Pharmacogenet Genom, 2008; 18: 99-107.
• Lonjou C, Thomas L, Borot N, Ledger N, Toma de C, LeLouet H, Graf E, Schumacher M, Hovnanian A, Mockenhaupt M, Roujeau J-C, (for the RegiSCAR group): A marker for Stevens-Johnson syndrome ...: ethnicity matters. The Pharmacogenomics Journal, 2006; 6: 1-4.
• Marx D, Schauer A, Reiche C, May A, Umenhofer L, Reles A, Rauschecker H, Sauer R, Schumacher M: C-erbB2 expression in corelation to other biological parameters of breast cancer J Cancer Res Clin, 1990; 116: 15-20.
• Maurer TB, Ochsner PE, Schwarzer G, Schumacher M: Increased loosening of cemented straight stem prostheses made from titanium alloys. An analysis and comparison with prostheses made of cobalt-chromium-nickel alloy. Int Orthop, 2001; 25: 77-80.
• Meerpohl HG, Sauerbrei W, Kühnle H, Schumacher M, Pfleiderer A for the German, Ovarian Cancer Study Group: Randomized study comparing carboplatin/cyclophosphamide and cisplatin/cyclophosphamide as first-line treatment in patients with stage III/IV epithelial ovarian cancer and small volume disease Gynecologic Oncology, 1997; 66: 75-84.
• Meier-Hirmer C, Schumacher M: Multi-state model for studying an intermediate event using time-dependent covariates: application to breast cancer. Bmc Med Res Methodol, 2013; 13 (online): 80. : http://dx.doi.org/10.1186/1471-2288-13-80
• Meyer E, Beyersmann J, Bertz H, Wenzler-Röttele S, Babikir R, Schumacher M, Daschner FD, Rüden H, Dettenkofer M the ONKO-KISS Study Group: Risk factor analysis of blood stream infection and pneumonia in neutropenic patients after peripheral blood stem-cell transplantation. Bone Marrow Transpl, 2007; 39: 173-178.
• Momm F, Kaden M, Tannock I, Schumacher M, Hasse J, Henke M: Dose escalation of gemcitabine concomitant with radiation and cisplatin for nonsmall cell lung cancer. A phase 1-2 study. Cancer, 2010; 116: 4833-4839. (download: http://dx.doi.org/10.1002/cncr.25366)
• Mross K, Holländer N, Hauns B, Schumacher M, Maier-Lenz H: The pharmacokinetics of a 1-h paclitaxel infusion. Cancer Chemoth Pharm, 2000; 45: 463-470.
• Müller C, Caputo A, Schumacher M, Raab G, Schütte M, Hilfrich J, Kaufmann M, von Minckwitz G: Clinical response by palpation during primary systemic therapy with four dose-dense cycles doxorubicin and docetaxel in patients with operable breast cancer: Further results from a randomised controlled trial. Eur J Cancer, 2007; 43: 1654-1661.
• Nieminen P, Carpenter JR, Rücker G, Schumacher M: The relationship between quality of research and citation frequency. BMC Medical Research Methodology, 2006; 6 (42): 1-8.
• Nieminen P, Rücker G, Miettunen J, Carpenter J, Schumacher M: Statistically significant papers in psychiatry were cited more often than others. J Clin Epidemiol, 2007; 60: 939-946.
• Ohneberg K, Wolkewitz M, Beyersmann J, Palomar-Martinez M, Olaechea-Astigarraga P, Alvarez-Lerma F, Schumacher M: Analysis of Clinical Cohort Data Using Nested Case-control and Case-cohort Sampling Designs: A Powerful and Economical Tool. Method Inform Med, 2015; 54: 505-514. : http://dx.doi.org/10.3414/ME14-01-0113
• Olschewski M, Schulgen G, Schumacher M: Contribution to the discussion on the paper of D.R. Cox et al. on "Quality-of-life assessment: Can we keep it simple?". Journal of the Royal Statistical Society A, 1992; 155: 385-386.
• Olschewski M, Schulgen G, Schumacher M, Altman DG: Quality of life assessment in clinical research. British Journal of Cancer, 1994; 70: 1-5.
• Olschewski M, Schumacher M: 'Lebensqualität' als Kriterium in der Therapieforschung. Intensivmedizin und Notfallmedizin, 1993; 30: 522-527.
• Olschewski M, Schumacher M, Davis K: Analysis of randomized and nonrandomized patients in clinical trials using the comprehensive cohort follow-up study design. Controlled Clinical Trials, 1992; 13: 226-239.
• Pfleiderer A, Meerpohl HG, Sauerbrei W, Teufel G, Schumacher M: Are there different types of ovarian cancer? J Cancer Res Clin, 1990; 116: 1077.
• Pielen A, Pantenburg S, Schmoor C, Schumacher M, Feltgen N, Junker B, Callizo J, for the EAGLE Study Group: Predictors of prognosis and treatment outcome in central retinal artery occlusion: local intra-arterial fibrinolysis vs. conservative treatment. Neuroradiology, 2015; 57: 1055-1062. : http://dx.doi.org/10.1007/s00234-015-1588-3
• Porzelius C, Binder H, Schumacher M: Parallelized prediction error estimation for evaluation of high-dimensional models. Bioinformatics, 2009; 25: 827-829. : http://dx.doi.org/10.1093/bioinformatics/btp062
• Porzelius C, Schumacher M, Binder H: A general, prediction error-based criterion for selecting model complexity for high-dimensional survival models. Stat Med, 2010; 29: 830-838. : http://dx.doi.org/10.1002/sim.3765
• Porzelius C, Schumacher M, Binder H: Sparse regression techniques in low-dimensional survival data settings. Stat Comput, 2010; 20: 151-163. : http://dx.doi.org/10.1007/s11222-009-9155-6
• Porzelius C, Schumacher M, Binder H: The benefit of data-based model complexity selection via prediction error curves in time-to-event data. Computation Stat, 2011; 26: 293-302. : http://dx.doi.org/10.1007/s00180-011-0236-6
• Rauschecker HF, Gatzemeier W, Sauer R, Seegenschmiedt M, Schauer A, Ummenhofer L, Sauerbrei W, Schmoor C, Schumacher M: German Breast Cancer Study Group study on therapy of small breast cancer. Four-year results. Breast Cancer Res Tr, 1993; 27: 142.
• Rauschecker HF, Gatzemeier W, Sauer R, Seegenschmiedt MH, Schauer A, Ummenhofer L, Sauerbrei W, Schmoor C, Schumacher M: Erste Ergebnisse des Projekts der Deutschen Brustkrebsstudiengruppe (GBSG) zur "Brusterhaltenden Therapie des kleinen Mammacarcinoms". Der Chirurg, 1992; 63: 495-500.
• Rauschecker HF, Gatzemeier W, Schumacher M, Sauerbrei W, Schmoor C, Sauer R, Seegenschmidt MH, Schauer A, Ummenhofer L, Scheurlen H: Concept and first results related to the structural relationship of various prognostic factors Tumor Diagnostik und Therapie, 1990; 11: 243-248.
• Rauschecker HF, Sauerbrei W, Gatzemeier W, Sauer R, Schauer A, Schmoor C, Schumacher M for the German, Breast Cancer Study Group: Eight-year results of a prospective non-randomised study on therapy of small breast cancer. European Journal of Cancer, 1998; 34: 315-323.
• Rauschecker HF, Sauer R, Schauer A, Schumacher M., Olschewski M, Sauerbrei W, Seegenschmiedt MH, Schmoor C: Therapy of small breast cancer - Four-year results of a prospectiv non-randomized study. Breast Cancer Research and Treatment, 1995; 34: 1-13.
• Reiser V, Porzelius C, Stampf S, Schumacher M, Binder H: Can matching improve the performance of boosting for identifying important genes in observational studies? Computation Stat, 2013; 28: 37-49. (download: http://dx.doi.org/10.1007/s00180-012-0306-4)
• Rücker G, Reiser V, Motschall E, Binder H, Meerpohl JJ, Antes G, Schumacher M: Boosting qualifies capture–recapture methods for estimating the comprehensiveness of literature searches for systematic reviews. J Clin Epidemiol, 2011; 64: 1364-1372. : http://dx.doi.org/10.1016/j.jclinepi.2011.03.008
• Rücker G, Schoop R, Beyersmann J, Schumacher M, Zuschneid I: Are KISS data representative of German intensive care units? - Statistical issues. Method Inform Med, 2006; 45: 424-429.
• Rücker G, Schumacher M: Simpson's paradox visualized: The example of the Rosiglitazone meta-analysis. BMC Medical Research Methodology, 2008; 8:34 (online). : http://doi: 10.1186/1471-2288-8-34
• Rücker G, Schumacher M: Summary ROC curve based on a weighted Youden index for selecting an optimal cutpoint in meta-analysis of diagnostic accuracy. Stat Med, 2010; 29: 3069-3078. : http://dx.doi.org/10.1002/sim.3937
• Rücker G, Schwarzer G, Carpenter JR, Binder H, Schumacher M: Treatment-effect estimates adjusted for small-study effects via a limit meta-analysis. Biostatistics, 2011; 12: 122-142. : http://dx.doi.org/10.1093/biostatistics/kxq046
• Rücker G, Schwarzer G, Carpenter JR, Schumacher M: Undue reliance on I^2 in assessing heterogeneity may mislead. BMC Medical Research Methodology, 2008; 8 (online). : http://dx.doi.org/doi:10.1186/1471-2288-8-79
• Rüden H, Gastmeier P, Daschner F, Schumacher M: Nosokomiale Infektionen in Deutschland. Epidemiologie in den alten und neuen Bundesländern Deutsche Medizinische Wochenschrift, 1996; 42: 1281-1287.
• Rüden H, Gastmeier P, Daschner F, Schumacher M: Nosokomiale Infektionen in Deutschland. Epidemiologie in den alten und neuen Bundesländern. Deutsche Medizinische Wochenschrift, 1996; 42: 1281-1287.
• Rüden H, Gastmeier P, Daschner F, Schumacher M: Nosocomial and community-acquired infections in Germany. Summary of the results of the first national prevalence study (NIDEP). Infection, 1997; 25: 199-202.
• Sariyar M, Schumacher M, Binder H: A boosting approach for adapting the sparsity of risk prediction signatures based on different molecular levels. Stat Appl Genet Mol, 2014; 13: 343-357. : http://dx.doi.org/10.1515/sagmb-2013-0050
• Sauerbrei W, Bastert G, Bojar H, Beyerle C, Neumann RLA, Schmoor C, Schumacher M for the German, Breast Cancer Study Group: Randomized 2x2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients: An update based on 10 years' follow-up. J Clin Oncol, 2000; 18: 94-101.
• Sauerbrei W, Blettner M, Schmoor C, Bojar H, Schumacher M for the German, Breast Cancer Study Group: The effect of oral contraceptive use on the prognosis of node positive breast cancer patients. European Journal of Cancer, 1998; 34: 1348-1351.
• Sauerbrei W, Blettner M, Schumacher M: Letters Re: Meta-analysis comparing cisplatin total dose intensity and survifal: a critical reappraisal Gynecologic Oncology, 1996; 62: 427-429.
• Sauerbrei W, Blettner M, Schumacher M: The importance of basic statistical principles for the intepretation of epidemiological data Onkologie, 1997; 20: 455-460.
• Sauerbrei W, Graf E, Schumacher M: Randomisation und Patientenaufklärung. Notwendigkeit der Randomisation aus methodischer Sicht Onkologie, 1996; 19: 184-190.
• Sauerbrei W, Hübner K, Schmoor C, Schumacher M for the German, Breast Cancer Study Group: Validation of existing and development of new prognostic classification schemes in node negative breast cancer. Breast Cancer Research and Treatment, 1997; 42: 149-163.
• Sauerbrei W, Royston P, Bojar H, Schmoor C, Schumacher M and the German Br: Modelling the effects of standard prognostic factors in node-positive breast cancer. British Journal of Cancer, 1999; 79: 1752-1760.
• Sauerbrei W, Schmoor c, Schumacher M, for the GBSG: Identification of high and low risk groups in node negative breast cancer patients. Development and validation of indices. Breast Cancer Res Tr, 1993; 27: 139.
• Sauerbrei W, Schumacher M: A bootstrap resampling procedure for model building: Application to the Cox regression model. Stat Med, 1992; 11: 2093-2109.
• Sauerbrei W, Schumacher M: Basic statistical principles for the evaluation of risk factors. 8th International congress on the ultrasonic examination of the breast, Heidelberg, 1.-4.7.1993. Bildgebung - Imaging, 1993; 60: 5.
• Sauerbrei W, Schumacher M: Aspekte der statistischen Evaluation neuer Prognosefaktoren: Illustration bei Studien in der Onkologie. Geburtshilfe und Frauenheilkunde, 1999; 59: 483-487.
• Sauer R, Rauschecker HF, Schauer A, Schumacher M, Seegenschmiedt MH: Brusterhaltende Therapie des frühen Mammakarzinoms: vorlaäufige Ergebnisse der deutschen Brustkrebs-Studie-1. tagungsbericht 71. deutscher Röntgenkongreß, Karlsruhe 1990 Zentralblatt für Radiologie, 1990; 141: 351.
• Sauer R, Rauschecker HP, Gatzemeier W, Schumacher M, Sauerbrei W, Seegenschmiedt MH, Schauer A, Marx D: Therapy of small breast cancer - comparison between mastectomy and breast preserving therapy. International Journal Radiation Oncology Biol. Phys., 1991; 21 Suppl. 1: 129-130.
• Sauer R, Schauer A, Rauschecker HF, Schumacher M, Gatzemeier W, Sauerbrei W, Dunst J, Seegenschmiedt MH, Marx D, for the German Breast Cancer Study Group:: Breast preservation versus mastectomy in early breast cancer - 1991 update of the GBSG 1 - protocol and prognostic factors. Strahlentherapie und Onkologie, 1992; 168: 191-202.
• Sauer R, Schauer A, Rauschecker HF, Schumacher M, Gatzemeier W, Schmoor C, Dunst J, Seegenschmidt MH, Marx D: Therapy of small breast cancer: A prospective study on 1036 patients with special emphasis on prognostic factors. International Journal Radiation Oncology Biol. Phys., 1992; 23: 907-914.
• Schäfer H, Berger J, Biebler K-E, Feldmann U, Greiser E, Jöckel K-H, Michaelis J, Neiss A, Raspe HH, Robra B-P, Schumacher M, Trampisch H-J, Victor N, Windeler J: Empfehlungen für die Erstellung von Studienprotokollen (Studienplänen) für klinische Studien. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1999; 30: 141-154.
• Schauer A, Korabiowska M, Kellner S, Schumacher M, Sauer R, Bojar H, Rauschecker H: Grading system for breast cancer. Anticancer Research, 1998; 18: 2139-2144.
• Schauer A, Marx D, Ummenhofer L, Rauschecker HF, Gatzemeier W, Sauer R, Schumacher M, Sauerbrei W: Die Multicenterstudie Kleines Mammakarzinom: Vorläufige Ergebnisse - Neue Aspekte. Deutsches Ärzteblatt, 1990; 87: C2125-C2130.
• Schmidt DP, Schulte Mönting J, Schumacher M: Prognosis of central retinal artery occlusion: Local intraarterial fibrinolysis versus conservative treatment. Am J Neuroradiol, 2002; 23 (8): 1301-1307.
• Schmoor, C, Sauerbrei, W, Schumacher, M: Sample size considerations for the evaluation of prognostic factors in survival analysis Stat Med, 2000; 19: 441-452.
• Schmoor C, Bastert G, Dunst J, Bojar H, Christmann D, Unbehaun V, Tümmers G, Bauer W, Sauerbrei W, Schumacher M for the German Breast Cancer Study Group: Randomized trial on the effect of radiotherapy in addition to 6 cycles of CMF in node positive breast cancer patients Int J Cancer, 2000; 86: 408-415.
• Schmoor C, Caputo A, Schumacher M: Evidence from nonrandomized studies: A case study on the estimation of causal effects. Am J Epidemiol, 2008; 167: 1120-1129.
• Schmoor C, Eisele C, Graf E, Sauerbrei W, Klingele B, Hellmer A, Rossner R, Schumacher M: Arbeitsweisen des Methodischen Zentrums am Institut für Medizinische Biometrie und Medizinische Informatik der Universität Freiburg bei der biometrischen Betreuung klinischer Studien Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1997; 28: 253-274.
• Schmoor C, Olschewski M, Sauerbrei W, Schumacher M: Long-term follow-up of patients in four prospective studies of the German Breast Cancer Study Group (GBSG): A summary of key results. Onkologie, 2002; 25: 143-150.
• Schmoor C, Olschewski M, Schumacher M: Randomized and non-randomized patients in clinical trials: experiences with comprehensive cohort studies Statistics in Medicine, 1996; 15: 263-271.
• Schmoor C, Sauerbrei W, Baster G, Schumacher M for the German, Breast Cancer Study Group, (GBSG): Role of isolated locoregional recurrence of breast cancer: results of four prospective studies. Journal of Clinical Oncology, 2000; 18: 1696-1708.
• Schmoor C, Sauerbrei W, Bastert G, Bojar H, Schumacher M for the German Breast Cancer Study Group (GBSG): Long-term prognosis of breast cancer patients with 10 or more positive lymph nodes treated with CMF. Eur J Cancer, 2001; 37: 1123-1131.
• Schmoor C, Schumacher M: Adaptive statistical procedures for the analysis of nonmonotone dose-response relationships. Biometrie und Informatik in Medizin und Biologie, 1992; 23: 113-126.
• Schmoor C, Schumacher M: High-dose chemotherapy as adjuvant treatment for breast cancer - some statistical arguments Onkologie, 1996; 19: 78-80.
• Schmoor C, Schumacher M: Effects of covariate omission and categorization when analysing randomized trials with the Cox model. Statistics in Medicine, 1997; 16: 225-237.
• Schmoor C, Schumacher M: Methodological arguments for the necessity of randomized trials in high-dose chemotherapy for breast cancer. Breast Cancer Research and Treatment, 1999; 54: 31-38.
• Schmoor C, Schumacher M, Finke J, Beyersmann J: Competing risks and multistate models. Clin Cancer Res, 2013; 19: 12-21. : http://dx.doi.org/10.1158/1078-0432.CCR-12-1619
• Schmoor C, Ulm K, Schumacher M: Comparison of the Cox-model anf the regression tree procedure in analyzing a randomized clinical trial. Stat Med, 1993; 12: 2351-2366.
• Schoop R, Beyersmann J, Schumacher M, Binder H: Quantifying the predictive accuracy of time-to-event models in the presence of competing risks. Biometrical J, 2011; 53: 88-112. : http://dx.doi.org/10.1002/bimj.201000073
• Schoop R, Graf E, Schumacher M: Quantifying the predictive performance of prognostic models for censored survival data with time-dependent covariates. Biometrics, 2008; 64: 603-610.
• Schoop R, Schumacher M, Graf E: Measures of prediction error for survival data with longitudinal covariates. Biometrical J, 2011; 53: 275-293. : http://dx.doi.org/10.1002/bimj.201000145
• Schröder T, Schumacher M: Graphical aids for the analysis of drug cumulation and deviations from planned treatment schedule in cyclic chemotherapy Onkologie, 1997; 20: 113-116.
• Schulgen G, Kropec A, Kappstein I, Daschner F, Schumacher M: Estimation of extra hospital stay attributable to nosocomial infections: heterogeneity and timing of events J Clin Epidemiol, 2000; 53: 409-417.
• Schulgen G, Lausen B, Olsen J, Schumacher M: Outcome-oriented cutpoints in analysis of quantitative exposures. American Journal of Epidemiology, 1994; 140: 172-184.
• Schulgen G, Olschewski M, Krane V, Wanner C, Ruf G, Schumacher M: Sample sizes for clinical trials with time-to-event endpoints and competing risks. Contemp Clin Trials, 2005; 26: 386-395.
• Schulgen G, Schmoor C, Sauerbrei W, Schumacher M: A note on estimating local recurrence rates in clinical trials on the treatment of breast cancer Breast Cancer Research and Treatment, 1998; 49: 87-91.
• Schulgen G, Schumacher M: Estimation of prolongation of hospital stay attributable to nosocomial infections: New approaches based on multistate models Lifetime Data Analysis, 1996; 2: 219-240.
• Schumacher M: Evaluation of nonproportional treatment effects in cancer clinical trials. Cancer Invest, 1990; 8: 91-98.
• Schumacher M: Methodische Grundlagen klinischer Forschung - Reminiszenzen an Herbert Immich und seine Beiträge zur Medizinischen Statistik. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2004; 35: 44-53.
• Schumacher M: Wie die Medizinische Statistik nach Freiburg kam. - Eine historische Perspektive. GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005; 1 (2): DOC-07.
• Schumacher M, Allignol A, Beyersmann J, Binder N, Wolkewitz M: Hospital-acquired infections—appropriate statistical treatment is urgently needed! Int J Epidemiol, 2013; 42: 1502-1508. : http://dx.doi.org/10.1093/ije/dyt111
• Schumacher M, Bastert G, Bojar H, Hübner K, Olschewski M, Sauerbrei W, Schmoor C., Beyerle C., Neumann R.L.A., Rauschecker H.F. for the Germ, Cancer Study Group (GBSG): Randomized 2x2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients. Journal of Clinical Oncology, 1994; 12: 2086-2093.
• Schumacher M, Bastert G, Bojar H, Hübner K, Sauerbrei W, Schmoor C, Olschewski M, for the German Breast Cancer Study Group: A randomized clinical trial evaluating the duration of chemotherapy in patients with primary, node-positive breast cancer. The Breast, 1993; 2: 194.
• Schumacher M, Beck M, Roßner R: European Cancer Clinical Trial Register (ECCTR) - eine aktuelle, europaweite Informationsquelle über Theapiestudien in der Onkologie Forum DKG, 1996; 11: 220-223.
• Schumacher M, Binder H, Gerds T: Assessment of survival prediction models based on microarray data. Bioinformatics, 2007; 23: 1768-1774.
• Schumacher M, Graf E, Gerds T: How to assess prognostic models for survival data: a case study in oncology. Method Inform Med, 2003; 42: 564-571.
• Schumacher M, Holländer N, Sauerbrei W: Resampling and cross-validation techniques: A tool to reduce bias caused by model building? Statistics in Medicine, 1997; 16: 2813-2827.
• Schumacher M, Olschewski M: Statistical analysis of quality of life data in cancer clinical trials. Stat Med, 1990; 9: 749-763.
• Schumacher M, Olschewski M, Sauerbrei W: On the importance of controlled clinical trials in oncology. Journal of Cancer Research and Clinical Oncology, 1992; 118: R 159.
• Schumacher M, Olschewski M, Schulgen G: Assessment of quality of life in clinical trials. Stat Med, 1991; 10: 1915-1930.
• Schumacher M, Roßner R, Vach W: Neural networks and logistic regression: Part I Computational Statistics & Data Analysis, 1996; 21: 661-682.
• Schumacher M, Sauerbrei W, Schmoor C: Prognostische Faktoren in den GBSG-Mammakarzinomstudien I-III. Zentralblatt Radiologie, 1993; 147: 793.
• Schumacher M, Schmidt D, Jurklies B, Gall C, Wanke I, Schmoor C, Maier-Lenz H, Solymosi L, Brueckmann H, Neubauer AS, Wolf A, Feltgen N, and EAGLE-Study Group: Central retinal artery occlusion: Local intra-arterial fibrinolysis versus conservative treatment, a multicenter randomized trial. Ophthalmology, 2010; 117: 1367-1375. : http://dx.doi.org/10.1016/j.ophtha.2010.03.061
• Schumacher M, Schmoor C, Plog A, Schwarzwald R, Taschner Ch, Echternach M, Richter B, Spahn C: Motor functions in trumpet playing-a real-time MRI analysis. Neuroradiology, 2013; 55 (9): 1171-1181. : http://dx.doi.org/10.1007/s00234-013-1218-x
• Schumacher M, Schmoor C, Sauerbrei W, Schauer A, Umenhofer L, Gatzemeier W, Rauschecker HF: The prognostic effect of histological tumor grade in node-negative breast cancer patients. Breast Cancer Res Tr, 1993; 25: 235-245.
• Schumacher M, Schmoor C, Sauerbrei W, Schauer A, Umenhofer L, Gatzemeier W, Rauschecker HF, fot the German Breast Cancer Study Group (GBSG): The prognostic effect of histological tumor grade in noce-negative breast cancer patients. The Breast, 1993; 2: 205.
• Schumacher M, Schulte Mönting J, Stoeter P, Warmuth-Metz M, Sloymosi L: Magnetic resonance imaging compared with biopsy in the diagnosis of brainstem diseases of childhood: a multicenter review. J Neurosurg, 2007; 106 Suppl. 2: 111-119.
• Schumacher M, Wangler M, Wolkewitz M, Beyersmann J: Attributable mortality due to nosocomial infections - A simple and useful application of multistate models. Method Inform Med, 2007; 46: 595-600.
• Schwarzer G, Antes G, Schumacher M: Inflation of type I error rate in two statistical tests for the detection of publication bias in meta-analyses with binary outcomes. Stat Med, 2002; 21: 2465-2477.
• Schwarzer G, Antes G, Schumacher M: A test for publication bias in meta-analysis with sparse binary data. Stat Med, 2007; 26: 721-733.
• Schwarzer G, Galandi D, Antes G, Schumacher M: Meta-Analyse randomisierter klinischer Studien, Publikations-Bias und Evidence-Based Medicine (EBM) Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2000; 31: 1-21.
• Schwarzer G, Nagata T, Mattern D, Schmelzeisen R, Schumacher M: Comparison of fuzzy inference, logistic regression, and classification trees (CART) for the prediction of cervical lymph node metastasis in carcinoma of the tongue. Method Inform Med, 2003; 42 (5): 572-577.
• Schwarzer G, Schumacher M: Statistische Tests zum Vergleich zweier Behandlungsmethoden. Klassisches Testverfahren oder Äquivalenztest? Nervenheilkunde, 1997; 16: 442-446.
• Schwarzer G, Schumacher M: Artificial neural networks for diagnosis and prognosis in prostate cancer. Seminars in Urologic Oncology, 2002; 20 (2): 89-95.
• Schwarzer G, Schumacher M, Maurer TB, Ochsner PE: Statistical analysis of failure times in total joint replacement. J Clin Epidemiol, 2001; 54: 997-1003.
• Schwarzer G, Vach W, Schumacher M: On the misuses of artificial neural networks for prognostic and diagnostic classification in oncology Stat Med, 2000; 19: 541-561.
• Schwarzer G., Galandi D., Antes G., Schumacher M.: Meta-Analyse randomisierter klinischer Studien, Publikations-Bias und Evidence-Based Medicine (EBM) Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2000; 31: 1-21.
• Seegenschmiedt M, Sauerbrei W, Sauer R, for the Gerrman Breast Study Group (GBSG): Schumacher M, Schauer A, Rauschecker HF, for participating institutions within the GBSG: Dinkloh H, Dühmke E, Haase KD, Haase W, Heisen E, Heinze HG, Janik I, Szepesi S: Quality control review for radiotherapy of small breast cancer: Analysis of 708 patients in the GBSG 1 trial. Stahlentherapie und Onkologie, 1993; 6: 339-350.
• Seegenschmiedt MH, Sauer R, Sauerbrei W, Schumacher M, Gatzemeier W, Rauschecker HF: Qualitätskontrolle (QC) der perkutanen Radiotherapie (RT) beim kleinen Mammakarzinom: Ergebnisse bei 708 Patienten in der GBSG 1 Studie. Zentralblatt Radiologie, 1993; 147: 940-941.
• Seegenschmiedt MH, Sauer R, Sauerbrei W, Schumacher M, Gatzemeier W, Rauschecker HF: Spätfolgen nach perkutaner Radiotherapie beim kleinen Mammakarzinom. Erste Ergebnisser der GBSG 1 Studie. Zentralblatt für Radiologie, 1993; 147: 941.
• Seegenschmiedt MH, Sauer R, Schumacher M, Sauerbrei W, Rauschecker HF, Gatzemeier W: Quality control for external beam radiotherapy of small breast cancer. Radiology, 1992; 185: 295.
• Sekula P, Caputo A, Dunant A, Roujeau J-C, Mockenhaupt M, Sidoroff A, Schumacher M: An application of propensity score methods to estimate the treatment effect of corticosteroids in patients with severe cutaneous adverse reactions. Pharmacoepidem Dr S, 2010; 19: 10-18. : http://dx.doi.org/10.1002/pds.1863
• Sekula P, Dunant A, Mockenhaupt M, Naldi L, Bouwes Bavinck JN, Halevy S, Kardaun S, Sidoroff A, Liss Y, Schumacher M, Roujeau J-C, for the RegiSCAR study group: Comprehensive survival analysis of a cohort of patients with Stevens–Johnson syndrome and toxic epidermal necrolysis. J Invest Dermatol, 2013; 133: 1197-1204. : http://dx.doi.org/10.1038/jid.2012.510
• Sekula P, Liss Y, Davidovici B, Dunant A, Roujeau J-C, Kardaun S, Naldi L, Schumacher M, Mockenhaupt M: Evaluation of SCORTEN on a cohort of patients with Stevens-Johnson Syndrome and toxic epidermal necrolysis included in the RegiSCAR Study. J Burn Care Res, 2011; 32: 237-245. : http://dx.doi.org/10.1097/BCR.0b013e31820aafbc
• Sreseli RT, Binder H, Kuhn M, Digel W, Veelken H, Sienel W, Passlick B, Schumacher M, Martens UM, Zimmermann S: Identification of a 17-protein signature in the serum of lung cancer patients. Oncol Rep, 2010; 24: 263-270.
• Stampf S, Graf E, Schmoor C, Schumacher M: Estimators and confidence intervals for the marginal odds ratio using logistic regression and propensity score stratification. Stat Med, 2010; 29: 760-769. : http://dx.doi.org/10.1002/sim.3811
• Stollhoff R, Sauerbrei W, Schumacher M: An experimental evaluation of boosting methods for classification. Method Inform Med, 2010; 3: 219-229. : http://dx.doi.org/10.3414/ME0543
• Ulm, K, Schmoor C, Sauerbrei W, Kemmler G, Aydemir Ü, Müller B, Schumacher M: Strategien zur Auswertung einer Therapiestudie mit der Überlebenszeit als Zielkriterium. Biometrie und Informatik in Medizin und Biologie, 1989; 20: 171-205.
• Vach K, Sauerbrei W, Schumacher M: Variable selection and shrinkage: comparison of some approaches. Stat Neerl, 2001; 55: 53-75.
• Vach W, Roßner R, Schumacher M: Neural networks and logistic regression: Part II Computational Statistics & Data Analysis, 1996; 21: 683-701.
• Vach W, Schumacher M: Logistic regression with incompletely abserved categorical covariates: A comparison of three approaches. Biometrika, 1993; 80: 353-362.
• Vach W, Schumacher M: Behandlung von fehlenden Werten in den Einflußgrößen von Regressionsmodellen - Ein Überblick Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1996; 27: 48-66.
• Wangler M, Beyersmann J, Schumacher M: changeLOS: An R-package for change in length of hospital stay based on the Aalen-Johansen estimator R News, 2006; 6: 31-35.
• Wehberg S, Schumacher M: A comparison of nonparametric error rate estimation methods in classification problems. Biometrical J, 2004; 46: 35-47.
• Winzer K-J, Sauerbrei W, Braun M, Liersch T, Dunst J, Guski H, Schumacher M, and for the German Breast Cancer Study Group (GBSG): Radiation therapy and tamoxifen after breast conserving surgery: updated results of a 2×2 randomized clinical trial in patients with low risk of recurrence. Eur J Cancer, 2010; 46: 95-101. : http://dx.doi.org/10.1016/j.ejca.2009.10.007
• Winzer K-J, Sauer R, Sauerbrei W, Schneller E, Jaeger W, Braun M, Dunst J, Liersch T, Zedelius M, Brunnert K, Guski H, Schmoor C, Schumacher M for the German Breast Cancer Study Group (GBSG): Radiation therapy after breast-conserving surgery - first results of a randomised clinical trial in patients with low risk of recurrence. Eur J Cancer, 2004; 40: 998-1005.
• Wischnewski N, Kampf G, Gastmeier P, Schlingmann J, Daschner F, Schumacher M, Rüden H: Prevalence of primary bloodstream infections in representativ German hospitals and their association with central and peripheral vascular catheters. Zentralblatt für Bakteriologie, 1998; 287: 93-103.
• Wischnewski N, Kampf G, Gastmeier P, Schlingmann J, Schumacher M, Daschner F, Rüden H: Nosocomial wound infections: A prevalence study and analysis of risk factors. International Surgery, 1998; 83: 93-97.
• Wolf A, Schumacher M, Neubauer AS, Schmoor C, Gall C, Jurklies B, Wanke I, Solymosi L, Brückmann H, Schmidt D, et al.: Vergleich der superselektiven intraarteriellen Fibrinolyse mit konservativer Therapie. Einsatz bei Patienten mit akutem nichtarteriitischem Zentralarterienverschluss. Ophthalmologe, 2010; 107: 799-805. : http://dx.doi.org/10.1007/s00347-010-2247-z
• Wolkewitz M, Allignol A, Harbarth S, de Angelis G, Schumacher M, Beyersmann J: Time-dependent study entries and exposures in cohort studies can easily be sources of different and avoidable types of bias. J Clin Epidemiol, 2012; 65: 1171-1180. : http://dx.doi.org/10.1016/j.jclinepi.2012.04.008
• Wolkewitz M, Allignol A, Schumacher M, Beyersmann J: Two pitfalls in survival analyses of time-dependent exposure: a case study in a cohort of Oscar Nominees. Am Stat, 2010; 64: 205-211. : http://dx.doi.org/10.1198/tast.2010.08259
• Wolkewitz M, Barnett AG, Palomar Martinez M, Frank U, Schumacher M, IMPLEMENT Study Group: Interventions to control nosocomial infections: study designs and statistical issues. J Hosp Infect, 2014; 86: 77-82. : http://dx.doi.org/10.1016/j.jhin.2013.09.015
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Modeling the effect of time-dependent exposure on intensive care unit mortality. Intens Care Med, 2009; 35: 826-832. : http://dx.doi.org/10.1007/s00134-009-1423-6
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Efficient risk set sampling when a time-dependent exposure is present. Matching for time to exposure versus exposure density sampling. Method Inform Med, 2009; 48: 438-443. : http://dx.doi.org/10.3414/ME9241
• Wolkewitz M, Beyersmann J, Schumacher M: A note on statistical association and causality derived from epidemiological ICU data. Intens Care Med, 2010; 36: 549. : http://dx.doi.org/10.1007/s00134-009-1721-z
• Wolkewitz M, Bruckner T, Schumacher M: Accurate variance estimation for prevalence ratios. Method Inform Med, 2007; 46: 567-571.
• Wolkewitz M, Cooper B, Barnett AG, Binder N, Schumacher M: Treatment of hospital-acquired pneumonia. Lancet Infect Dis, 2011; 11: 729. : http://dx.doi.org/10.1016/S1473-3099(11)70262-6
• Wolkewitz M, Cooper B, Palomar-Martinez M, Olaechea-Astigarraga P, Alvarez-Lerma F, Schumacher M: Nested case-control studies in cohorts with competing events. Epidemiology, 2014; 25: 122-125. : http://dx.doi.org/10.1097/EDE.0000000000000029
• Wolkewitz M, Cooper BS, Bonten MJM, Barnett AG, Schumacher M: Interpreting and comparing risks in the presence of competing events. Bmj-brit Med J, 2014; 349 (online): g5060. : http://dx.doi.org/10.1136/bmj.g5060
• Wolkewitz M, Cooper BS, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Barnett AG, Harbarth S, Schumacher M: Multilevel competing risk models to evaluate the risk of nosocomial infection. Crit Care, 2014; 18 (online): R64. : http://dx.doi.org/10.1186/cc13821
• Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Environmental contamination as an important route for the transmission of the hospital pathogen VRE: Modeling and prediction of classical interventions. Infectious Diseases: Research and Treatment, 2008; 1: 3-11.
• Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Statistical epidemic modeling with hospital outbreak data. Stat Med, 2008; 27: 6522-6531. : http://dx.doi.org/10.1002/sim.3419
• Wolkewitz M, Frank U, Philips G, Schumacher M, Davey P, on behalf of the BURDEN study group†: Mortality associated with in-hospital bacteraemia caused by Staphylococcus aureus: a multistate analysis with follow-up beyond hospital discharge. J Antimicrob Chemoth, 2011; 66: 381-386. : http://dx.doi.org/10.1093/jac/dkq424
• Wolkewitz M, Schumacher M: Simulating and analysing infectious disease data in a heterogeneous population with migration. Comput Meth Prog Bio, 2011; 104: 29-36. : http://dx.doi.org/10.1016/j.cmpb.2010.05.007
• Wolkewitz M, Vonberg RP, Grundmann H, Beyersmann J, Gastmeier P, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care, 2008; 12 (online): R44. : http://dx.doi.org/10.1186/cc6852
• Zander AR, Kröger N, Schmoor C, Krüger W, Möbus V, Frickhofen N, Metzner B, Schultze W, Berdel WE, Köenigsmann M, Thiel E, Wandt H, Possinger K, Trümer L, Kreienberg R, Carstensen M, Schmidt EH, Jänicke F, Schumacher M, Jonat W: High-dose chemotherapy with autologous hematopoietic stem-cell support compared with standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: First results of a randomized trial. J Clin Oncol, 2004; 22: 2273-2283.
• Zander AR, Schmoor C, Kröger N, Krüger W, Möbus V, Frickhofen N, Metzner B, Berdel WE, Koenigsmann M, Thiel E, Wandt H, Possinger K, Kreienberg R, Schumacher M, Jonat W: Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up. Ann Oncol, 2008; 19: 1082-1089.
• Zhao M, Stampf S, Valina C, Kienzle R-P, Ferenc M, Gick M, Essang E, Nührenberg T, Büttner HJ, Schumacher M, Neumann F-J: Role of euroSCORE II in predicting long-term outcome after percutaneous catheter intervention for coronary triple vessel disease or left main stenosis. Int J Cardiol, 2013; 168 (4): 3273-3279. : http://dx.doi.org/10.1016/j.ijcard.2013.04.136
• Zuschneid I, Geffers C, Sohr D, Kohlhase C, Schumacher M, Rüden H, Gastmeier P: Validation of surveillance in the intensive care unit component of the German Nosocomial Infections Surveillance System. Infection Control and Hospital Epidemiology, 2007; 28: 496-499.
• Zuschneid I, Rücker G, Schoop R, Beyersmann J, Schumacher M, Geffers C, Rüden H, Gastmeier P: Representativeness of the surveillance data in the intensive care unit component of the German Nosocomial Infections Surveillance System. Infect Cont Hosp Ep, 2010; 31: 934-938. : http://dx.doi.org/10.1086/655462

• Hauer, T, Lacour, M, Gastmeier, Schulgen G, Schumacher M, Rüden H, Daschner F: Nosokomiale Infektionen auf Intensivstationen. Eine bundesweite Prävalenzstudie (NIDEP). Anaesthesist, 1996; 45: 1184-1191.
• Hauer T, Huzly D, Gastmeier P, Schlingmann J, Schumacher M: Krankenhausinfektion in Gynäkologie und Geburtshilfe. Geburtshilfe und Frauenheilkunde, 1996; 56: 546-549.
• Kampf G, Gastmeier P, Wischnewski N, Schlingmann J, Schumacher M: Nosokomiale Infektionen in Deutschland - Erfassung und Prävention. NIDEP-Studie, Teil 1: Zur Prävalenz in der Chirurgie. Chirurg, 1996; 67: 637-642.
• Kampf G, Schumacher M, Daschner F, Rüden H: Postoperative Wundinfektionen in der Chirurgie - Prävalenz in Deutschland (NIDEP-Studie). Langenbecks Archiv für Chirurgie, Supplement II, 1996: 698-703.
• Kropec A, Schulgen G, Just H, Geiger K, Schumacher M: Scoring system for nosocomial pneumonia in ICUs. Intensive Care Medicine, 1996; 22: 1155-1161.
• Kropec A, Schulgen G, Schumacher M, Just H, Geiger K: Entwicklung eines Risiko Scores für nosokomiale Sepsis bei Intensivpflegepatienten Intensivmedizin, 1996; 33: 126-132.
• Lausen B, Schumacher M: Evaluating the effect of optimized cutoff values in the assessment of prognostic factors. Computational Statistics & Data Analysis, 1996; 21: 307-326.
• Rüden H, Daschner F, Schumacher M: Gegendarstellung der Studienleiter der NIDEPStudie zum Kommentar: Ist die NIDEPStudie geeignet zur Häufigkeitsbeurteilung und Bewertung Hygiene und Medizin, 1996; 21: 445-448.

• Beyersmann J, Allignol A, Schumacher M: Competing Risks and Multistate Models with R (Use R!)Springer Verlag, 2012 (Use R!). : http://www.springer.com/statistics/statistical+theory+and+methods/book/978-1-4614-2034-7
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., Heidelberg: Springer Verlag, 1. Auflage, 2002.
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., Berlin Heidelberg: Springer Verlag, 2. Auflage, 2007.
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., New York - Heidelberg: Springer, 3. Auflage, 2008 (Statistik und ihre Anwendungen). : http://dx.doi.org/10.1007/978-3-540-85136-3

• Binder H, Gerds T, Schumacher M: Sirivival Risk Prediction Using High-Dimensional Molecular Data. In: Shigeyuki Matsui, Marc Buyse, Richard Simon (Hrsg.): Design and Analysis of Clinical Trials for Predicitive Medicine. New York: Chapman & Hall/CRC Biostatistics Series, 2015; 271-294.
• Gerlach A, Holländer N, Ihorst G, Olschewski M, Sauerbrei W, Schlingmann J, Schmoor C, Schulgen G, Schwarzer G, Schumacher M: Freiburg contributions to biometry and clinical epidemiology. In: Joachim Kunert und Götz Trenkler (Hrsg.): Mathematical Statistics with Applications in Biometry, 1. Auflage. Lohmar Köln: Josef Eul Verlag, 2001; 49-70.
• Graf E, Sauerbrei W, Schumacher M, Schmoor C: Berücksichtigung prognostischer Faktoren bei der Planung von Therapiestudien. In: Kunath, H., Lochmann, U., Straube, R., Jöckel, K.H., Köhler, C.O. (Hrsg.): Medizinische Informatik, Biometrie und Epidemiologie. , 1995; 475-480.
• Lausen B, Sauerbrei W, Schumacher M: Classification and regression trees used for the exploration of prognostic factors measured on different scales. In: Dirschedl, P., Ostermann, R. (Hrsg.): Computational Statistics. Physica-Verlag, Heidelberg, 1994; 483-496.
• Ohneberg K, Schumacher M: Sample Size Calculation for Clinical Trials. In: John P. Klein, Joseph G. Ibrahim, Thomas Scheike (Hrsg.): Handbook of Survival Analysis, 1. Auflage. Boca Raton: Chapman and Hall/CRC, 2013; 571-594 (Handbooks of Modern Statistical Methods).
• Rüden H, Daschner F, Schumacher, M: Nosokomiale Infektionen in Deutschland - Erfassung und Prävention (NIDEP-Studie), Teil 1 Abschlußbericht und Anhänge. In: Bundesministerium für Gesundheit (Hrsg.): NOMOS Verlagsgesellschaft Baden-Baden, 1995.
• Sauerbrei W, Blettner M, Schumacher M: Basic statistical principles for the evaluation of risk factors. In: Madjar, H., Teubner, J., Hackelöer B-J (Hrsg.): Breast Ultrasound Update. Basel, Karger, 1994; 1-12.
• Sauerbrei W, Schumacher M: Klinische Studien als wichtiger Bestandtteil medizinischer Forschung: Aspekte der Planung, Durchführung und Auswertung In: Steiner W, Reck R, Dühmke E (Hrsg.): Funktonserhaltende Therapie des frühen Larynxkarzinoms Stuttgart New York: Thieme, 1990; 147-159.
• Sauerbrei W, Schumacher M: Boostrap and cross-validation to assess complexity of data-driven regression models In: Brause, RW and Hanisch, E (Hrsg.): Medical Data Analysis: first international symposium; proceedings Springer Berlin, 2000; 234-241.
• Sauerbrei W, Zaiss A, Lausen B, Schumacher M: Evaluierung prognostischer homogener Subpopulationen mit Hilfe der Methode der Klassifikationabäume. In: Guggenmoos-Holzmann I (Hrsg.): Quantitative Methoden in der Epidemiologie. Berlin - Heidelberg - New York: Springer, 1991; 229-234.
• Schauer A, Marx D, Lipp I, Meden H, Schumacher M, Sauerbrei W, Sauer R, Rauschecker H: Clinical and scientific aspects of HER 2/NEU erb B2-oncogenes: Biological relevance of c-erb B2-oncogene in malignant epithelial tumors. In: Löning J (Hrsg.): Clinical and scientific aspects of HER 2/NEU erb. International Symposium Hamburg 1991. Berlin: Springer, 1992.
• Schmoor C, Olschewski M, Schumacher M: Randomisierte und nicht-randomisierte Patienten in klinischen Therapiestudien: Erfahrungen mit dem CCS-Design. In: Kunath, H, Lochmann, U, Straube, R, Jöckel, KH, Köhler, CO (Hrsg.): Medizinische Informatik, Biometrie und Epidemiologie. , 1995; 444-449.
• Schmoor C, Schulgen G, Schumacher M: Studiendesign - Eine Einführung. In: Bassler D, Forster J, Antes G (Hrsg.): Evidenz-basierte Pädiatrie. Praxisnahes EBM-Handbuch für pädiatrische Diagnostik und Therapie Stuttgart, New York: Georg Thieme Verlag, 2001.
• Schröder T, Schumacher M: Graphische Methoden zur Analyse der Wirkstoffkumulation und Modifikation des Therapieschemas bei zyklischen Chemotherapien In: Medizinische Informatik, Biometrie und Epidemiologie GMDS , 1997; 378-381.
• Schumacher M: The Freiburg center of data analysis and model building (FDM): an interim report about an interdisciplinary cooperation. In: Klar, R, Opitz, O (Hrsg.): Classification and Knowledge Organization Springer-Verlag, 1997; 539-546.
• Schumacher M, Antes G, Olschewski M, Schmoor C: Überlebenszeitanalyse In: Rasch, D, Herrendörfer, G, Bock, J, Victor, N, Guiard, V (Hrsg.): Verfahrensbibliothek. Versuchsplanung und -auswertung. R. Oldenbourg Verlag, München Wien, 1998; 800-830.
• Schumacher M, Bastert G, Bojar H, Hübner K, Olschewski M, sauerbrei W, Schmoor C, for the German Breast Cancer Study Group (GBSG): A randomized clinical trial evaluating the duration of chemotherapy in patients with primary, node-positive breast cancer. In: Salmon SF (Hrsg.): Adjuvant therapy of cancer VII. Philadelphia: Lippincott, 1993; 193-203.
• Schumacher M, Holländer N, Schwarzer G, Binder H, Sauerbrei W: Prognostic Factor Studies. In: Crowley J, Hoering A (Hrsg.): Handbook of Statistics in Clinical Oncology, Third Edition. Chapman and Hall/CRC, 2012; 415-470.
• Schumacher M, Holländer N, Schwarzer G, Sauerbrei W: Prognostic Factor Studies. In: John Crowley (Hrsg.): Handbook of Statistics in Clinical Oncology New York - Basel: Marcel Dekker, Inc., 2001; 321-378.
• Schumacher M, Holländer N, Schwarzer G, Sauerbrei W: Prognostic Factor Studies. In: John Crowley and Donna Pauler Ankerst (Hrsg.): Handbook of Statistics in Clinical Oncology., 2. Auflage. Boca Raton, FL: Chapman & Hall /CRC, 2006; 289-333.
• Schumacher M, Olschewski M: Evaluierung von Lebensqualität in klinischen Studien. In: Meerpohl HG, Pfleiderer A, Profous CZ (Hrsg.): Das Rezidiv in der Gynäkologischen Onkologie. Berlin - Heiderlberg - New York: Springer-Verlag, 1990; 267-275.
• Schumacher M, Olschewski M: Auswertung randomisierter und nicht-randomisierter Patienten in klinischen Studien. In: Giani G, Repges R (Hrsg.): Biometrie und Informatik - neue Wege zur Erkenntnisgewinnung. Heidelberg: Springer-Verlag, 1990; 61-71.
• Schumacher M, Sauerbrei W: Statistische Aspekte der Planung, Durchführung und (Meta-) Analyse. In: Meerpohl HG, Pfleiderer A, Profous CZ (Hrsg.): Das Ovarialkarzinom. Bd. 2 Therapie. Berlin - Heidelberg: Springer-Verlag, 1993; 71-85.
• Schumacher M, Schmoor C: Statistical Analysis af the Ames assay. In: Hothorn L (Hrsg.): Statistical methods in toxicology. Berlin - Heidelberg - New York: Springer, 1991; 5-19.
• Schwarzer G, Antes G, Schumacher M: Statistical tests for the detection of bias in meta-analysis. In: Ralf Schulze, Heinz Holling, Dankmar Böhning (Hrsg.): Meta-Analysis. New Developments and Applications in Medical and Social Sciences. Göttingen: Hogrefe & Huber, 2003; 72-78.
• Schwarzer G, Vach W, Schumacher M: On the misuses of artificial neural networks for prognostic and diagnostic classification in oncology. In: Haux R, Kulikowski C (Hrsg.): Yearbook of Medical Informatics 2002 Stuttgart: Schattauer Verlagsgesellschaft mbH, 2002; 501-521.
• Vach W, Schumacher M: Logistic regression with incompletely observed covariates. In: Schach S, Trenkler G (Hrsg.): Data analysis and statistical inference - Festschrift in Honour of Friedhelm Eicker. Bergisch-Gladbach: Eul-Verlag, 1992; 219-138.

• Meerpohl HG, Sauerbrei W, Schumacher M, Pfleiderer A (Hrsg.): Welche Parameter beeinflussen die Größe des postoperativen Tumorrestes beim fortgeschrittenen Ovarialkarzinom?, Berlin: Springer-Verlag, 1990 (Berichte Gynäkologie Geburtshilfe 127).

• Beyersmann J, Gerds T, Schumacher M: Letters to the Editor. Snapinn, S.M., Jiang, Q., and Iglewicz, B. (2005), "Illustrating the impact of a time-varying covariate with an extended Kaplan-Meier estimator", The American Statistician, 59, 301-307: Comment by Beyersmann, Gerds, and Schumacher and Response. Am Stat, 2006; 60: 295-297.
• Beyersmann J, Meerpohl J, Dettenkofer M, Wolkewitz M, Schumacher M: Risk factors disrupting mucosal integrity and subsequent vancomycin-resistant enterococcus infection. Pediatr Blood Cancer, 2010; 54: 184. : http://dx.doi.org/10.1002/pbc.22268
• Beyersmann J, Schumacher M: Misspecified regression model for the subdistribution hazard of a competing risk Latouche A, Boisson V, Chevret S and Porcher R. Stat Med, 2007; 26: 1649-1651.
• Binder N, Schumacher M, Joly P: Re: “Incidence of Dementia Among Participants and Nonparticipants in a Longitudinal Study of Cognitive Aging” Am J Epidemiol, 2015; 181: 290-292. : http://dx.doi.org/10.1093/aje/kwu475
• Graf E, Schumacher M: Comments on 'The performance of different propensity score methods for estimating marginal odds ratios' by Peter C. Austin, Statistics in Medicine 2007; 26(16):3078-3094. Stat Med, 2008; 27: 3915-3917. : http://dx.doi.org/10.1002/sim.3271
• Höfling H, Eckert C, Schumacher M: "Classification of therapy resistance based on longitudinal biomarker profiles" by M. Kohlmann, L. Held and V. P. Grunert Biometrical Journal (2009) 51(4):610–626 Article: http://dx.doi.org/10.1002/bimj.200800157. Authors' reply: http://dx.doi.org/10.1002/bimj.201000119 Biometrical J, 2010; 52: 562-566. : http://dx.doi.org/10.1002/bimj.201000054
• Ihorst G, Waldschmidt J, Schumacher M, Wäsch R, Engelhardt M: Analysis of survival by tumor response: have we learnt any better? Ann Hematol, 2015; 94: 1615-1616. : http://dx.doi.org/10.1007/s00277-015-2426-8
• Jena S, Dreier G, Antes G, Schumacher M: Clinical trials. More transparency in EU testing? European Biotechnology News, 2010; 9 (5-6): 28-30.
• Rücker G, Graf E, Schumacher M: Letter to the editor concerning Shadish WR, Clark MH, Steiner PM: Can Nonrandomized Experiments Yield Accurate Answers? A Randomized Experiment Comparing Random and Nonrandom Assignments. Journal of the American Statistical Association. December 1, 2008, 103(484): 1334-1344. doi:10.1198/016214508000000733. [Website: http://pubs.amstat.org/doi/abs/10.1198/016214508000000733]. J Am Stat Assoc, 2010 (online): 1-6. : http://pubs.amstat.org/doi/suppl/10.1198/016214508000000733/suppl_file/Letter.pdf
• Rücker G, Schumacher M: Letter to the editor. Biostatistics, 2009; 10: 806-807. : http://dx.doi.org/10.1093/biostatistics/kxp021
• Rücker G, Schumacher M: Procalcitonin as a diagnostic marker for sepsis. Lancet Infect Dis, 2013; 13: 1012-1013. : http://dx.doi.org/10.1016/S1473-3099(13)70303-7
• Rücker G, Schwarzer G, Carpenter J, Schumacher M: Comments on ‘Empirical vs natural weighting in random effects meta-analysis’ by JJ Shuster, Statistics in Medicine 2009; 26, Published online, DOI: 10.1002/sim.3607. Stat Med, 2010; 29: 2963-2966. : http://dx.doi.org/10.1002/sim.3957
• Rücker G, Schwarzer G, Schumacher M, Carpenter J: Are large trials less reliable than small trials? J Clin Epidemiol, 2009; 62: 886-889. : http://dx.doi.org/10.1016/j.jclinepi.2009.03.007
• Sauerbrei W, Royston P, Schumacher M: Austin, P.C., and Tu, J.V. (2004), "Bootstrap Methods for developing predictive models", The American Statistician,58, 131-137: Comment by Sauerbrei, Royston, and Schumacher to reply. Am Stat, 2005; 59: 116-118.
• Sauerbrei W, Royston P, Schumacher M: Comments on ‘Performance of using multiple stepwise algorithms for variable selection’ by Ryan E. Wiegand, Statistics in Medicine 2010; 29:1647–1659. Stat Med, 2011; 30: 892-894. : http://dx.doi.org/10.1002/sim.4083
• Schumacher M, Rücker G, Schwarzer G: Meta-Analysis and the Surgeon General's Report on Smoking and Health. New Engl J Med, 2014; 370: 186-188. : http://dx.doi.org/10.1056/NEJMc1315315
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Regression modelling in hospital epidemiology: a statistical note. Crit Care, 2008; 12: 427. : http://dx.doi.org/10.1186/cc6991
• Wolkewitz M, Beyersmann J, Schumacher M: Consequences of immortal time bias on extra length of hospital stay due to nosocomial infections. Rapid Response to: Lévesque LE, Hanley JA, Kezouh A, Suissa S: Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ 2010; 340: b5087 [http://www.bmj.com/content/340/bmj.b5087.long/reply#bmj_el_233676]. Brit Med J, 2010 (online): 30 Mar. : http://www.bmj.com/content/340/bmj.b5087.long/reply#bmj_el_233676
• Wolkewitz M, Di Termini S, Cooper B, Meerpohl J, Schumacher M: Paediatric hospital-acquired bacteraemia in developing countries. Lancet, 2012; 379: 1484. : http://dx.doi.org/10.1016/S0140-6736(12)60624-2
• Wolkewitz M, Schumacher M: Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality. The Lancet Respiratory Medicine, 2014; 2 (online): e8-e9. : http://dx.doi.org/10.1016/S2213-2600(14)70115-8
• Wolkewitz M, Tacconelli E, Schumacher M: Aggressive versus conservative initiation of antibiotics. Lancet Infect Dis, 2013; 13: 387-388. : http://dx.doi.org/10.1016/S1473-3099(13)70063-X

• Bluemle A, Meerpohl J, Ruecker G, Antes G, Schumacher M, von Elm E: Reporting of eligibility criteria of randomised trials: empirical study comparing trial protocols to subsequent articles. J Epidemiol Commun H, 2011; 65: A216-A216. : http://dx.doi.org/10.1136/jech.2011.142976h.28
• Holländer N, Schumacher M: Zum Einfluss der Modellbildung auf die Schätzung von Konfidenzintervallen für prognostische Faktoren am Beispiel des Cutpointmodells. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2001; 32 (2-3): 177 (46. Jahrestagung der GMDS), Urban & Fischer (Hrsg). : http://www.urbanfischer.de/journals/ibe
• Motschall E, Rücker G, Antes G, Schumacher M: The number needed to read: are capture-recapture techniques feasible in searching literature of systematic reviews? Cochrane Db Syst Rev, 2009; 3 (online): CD000001. : http://onlinelibrary.wiley.com/o/cochrane/clcmr/articles/CMR-14037/frame.html

• Henderson R, Schumacher M: Clinical epidemiology and individualized medicine. Biometrical J, 2011; 53: 167-169. : http://dx.doi.org/10.1002/bimj.201000257
• Schumacher M: Probability estimation and machine learning—Editorial. Biometrical J, 2014; 56: 531-533. : http://dx.doi.org/10.1002/bimj.201400075