Forschungsbericht für das Jahr 1980-2015

Institut für Medizinische Biometrie und Statistik

Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

Forschungsschwerpunkte

• Biometrische Methodologie
• Epidemiologische Studien
• Klinische Studien
• Multizentrische Therapiestudien

Wissenschaftliche Projekte und Forschungsvorhaben

• GAGB-4-Studie.
  • Projektleitung: Prof. Dr. M. Schumacher
  • Laufzeit: 1994 bis 1995
  • Details zum Projekt
• Immunmodulatoren i.d. Krebstherapie.
  • Projektleitung: Prof. M. Schumacher
  • Laufzeit: 1995
  • Details zum Projekt
• Schu 756/3-1.
  • Projektleitung: Prof. Dr. M. Schumacher
  • Laufzeit: 1994 bis 1995
  • Details zum Projekt

Wissenschaftliche Publikationen

• Abouassi T, Hannig C, Mahncke K, Karygianni L, Wolkewitz M, Hellwig E, Al-Ahmad1 A: Does human saliva decrease the antimicrobial activity of chlorhexidine against oral bacteria? BMC Research Notes, 2014; 7 (online): 711. : http://dx.doi.org/10.1186/1756-0500-7-711
• Abouassi T, Wolkewitz M, Hahn P: Effect of carbamide peroxide and hydrogen peroxide on enamel surface: an in vitro study. Clin Oral Invest, 2011; 15: 673-680. : http://dx.doi.org/10.1007/s00784-010-0439-1
• Ahlbom A, Feychting M, Koskenvuo M, Olsen J, Pukkala E, Schulgen G, Verkasalo P: Electromagnetic fields and childhood cancer. The Lancet, 1993; 342: 1295-1296.
• Ahlert T, Sauerbrei W, Bastert G, Ruhland S, Bartik B, Simiantonaki N, Schumacher J, Häcker B, Schumacher M, Schirrmacher V: Tumor-cell number and viability as quality and efficacy parameters of autologous virus-modified cancer vaccines in patients with breast or ovarian cancer. Journal of Clinical Oncology, 1997; 15: 1354-1366.
• Ahrens W, Timmer A, Vyberg M, Fletcher T, Guenel P, Merler E, Merletti F, Morales Maria, Olsson H, Olsen J, Hardell L, Kaerlev L, Raverdy N, Lynge E: Risk factors for extrahepatic biliary tract carcinoma in men: medical conditions and lifestyle: Results from a European multicentre case-control study. Eur J Gastroen Hepat, 2007; 19: 623-630.
• Akl EA, Meerpohl JJ, Raad D, Piaggio G, Mattioni M, Paggi MG, Gurtner A, Mattarocci S, Tahir R, Muti P, , Schüneman HJ: Effects of assessing the productivity of faculty in academic medical centres: a systematic review. Can Med Assoc J, 2012; 184 (online): E602-E612. : http://dx.doi.org/10.1503/cmaj.111123
• Al-Ahmad A, Bucher M, Anderson AC, Tennert C, Hellwig E, Wittmer A, Vach K, Karygianni L: Antimicrobial Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (VIS + wIRA) Alters In Situ Oral Biofilms. Plos One, 2015; 10 (online): e0132107. : http://dx.doi.org/10.1371/journal.pone.0132107
• Al-Ahmad A, Roth D, Wolkewitz M, Wiedmann-Al-Ahmad M, Follo M, Ratka-Krüger P, Deimling D, Hellwig E, Hannig C: Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm. Clin Oral Invest, 2010; 14: 391-396. : http://dx.doi.org/10.1007/s00784-009-0318-9
• Al-Ahmad A, Wiedmann-Al-Ahmad M, Fackler A, Follo M, Hellwig E, Bächle M, Hannig C, Han J-S, Wolkewitz M, Kohal R: In vivo study of the initial bacterial adhesion on different implant materials. Arch Oral Biol, 2013; 58: 1139-1147. : http://dx.doi.org/10.1016/j.archoralbio.2013.04.011
• Al-Ahmad A, Wiedmann-Al-Ahmad M, Faust J, Bächle M, Follo M, Wolkewitz M, Hannig C, Hellwig E, Carvalho C, Kohal R: Biofilm formation and composition on different implant materials in vivo. J Biomed Mater Res B, 2010; 95: 101-109. : http://dx.doi.org/10.1002/jbm.b.31688
• Aldegheishem A, Alfaer A, Brezavšček M, Vach K, Eliades G, Att W: Wear behavior of zirconia substrates against different antagonist materials. International Journal of Esthetic Dentistry, 2015; 10: 468-485.
• Allgaier HP, Deibert P, Zuber I, Olschewski M, Blum HE: Percutaneous radiofrequency interstitial thermal ablation of small hepatocelluar carcinoma. The Lancet, 1999; 353: 1676-1677.
• Allgaier HP, Galandi D, Olschewski M, Blum HE: Randomisierte kontrollierte Studie: Radiofrequenz-Thermoablation von Lebermetastasen kolorektaler Karzinome Deutsches Ärzteblatt, 2003; 100 (41): A2666-A2667.
• Allgaier HP, Galandi D, Olschewski M, Blum HE: Radiofrequenz-Thermoablation von Lebermetastasen kolorektaler Karzinome Deut Med Wochenschr, 2003; 128 (38): 1976-1977.
• Allgaier H-P, Deibert P, Olschewski M, Spamer C, Blum U, Gerok W, Blum HE: Survival benefit of patients with inoperable hepatocellular carcinoma treated by a combination of transarterial chemoembolization and percutaneous ethanol injection - a single-center analysis including 132 patients. International Journal of Cancer, 1998; 79: 601-605.
• Allgaier H-P, Galandi D, Olschewski M, Blum HE: Nicht-chirurgische Therapie des hepatozellulären Karzinoms. Schweiz Rundsch Med Prax, 2002; 91 (35): 1387-1392. : http://www.praxis.ch
• Allignol A, Beyersmann J, Schumacher M: mvna: An R Package for the Nelson–Aalen Estimator in Multistate Models. R News, 2008; 8: 48-50. : http://CRAN.R-project.org/doc/Rnews
• Allignol A, Schumacher M, Beyersmann J: A note on variance estimation of the Aalen-Johansen estimator of the cumulative incidence function in competing risks, with a view towards left-truncated data. Biometrical J, 2010; 52: 126-137. : http://dx.doi.org/10.1002/bimj.200900039
• Allignol A, Schumacher M, Beyersmann J: Estimating summary functionals in multistate models with an application to hospital infection data. Computation Stat, 2011; 26: 181-197. : http://dx.doi.org/10.1007/s00180-010-0200-x
• Allignol A, Schumacher M, Wanner C, Drechsler C, Beyersmann J: Understanding competing risks: a simulation point of view. Bmc Med Res Methodol, 2011; 11 (online): 86. (download: http://dx.doi.org/10.1186/1471-2288-11-86)
• Alt KW, Munz M, Vach W: Hallstattzeitliche Grabhügel im Spiegel ihrer biologischen und sozialen Strukturen am Beispiel des Hügelgräberfeldes von Dattingen, Kr. Breisgau-Hochschwarzwald. Germania, 1995; 73: 281-316.
• Alt KW, Vach W, Frifelt K, Kunter M: Familienanalyse in kupferzeitlichen Kollektivgräbern aus Umm an-Nar; Abu Dhabi. Arabian archaelogy and epigraphy, 1995; 6: 65-80.
• Alt KW, Pichler S, Vach W, Huckenbeck W, Stloukal M: Early Bronce Age family burial from Velké Pavlovice. Verification of kinship hypthesis by odontologic and other nonmetric traits.E HOMO, 1996; 3: 252-266.
• Altman DG, Lausen B, Sauerbrei W, Schumacher M: Danger of using "optimal" cutpoints in the evaluation of prognostic factors. Journal of the National Cancer Institute, 1994; 86: 829-835.
• Andrews J, Guyatt G, Oxman AD, Alderson P, Dahm P, Falck-Ytter Y, Nasser M, Meerpohl J, Post PN, Kunz R, Brozek J, Vist G, Rind D, Akl EA, Schünemann HJ: GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol, 2013; 66 (7): 719-725. : http://dx.doi.org/10.1016/j.jclinepi.2012.03.013
• Andrews JC, Schünemann HJ, Oxman AD, Pottie K, Meerpohl JJ, Coello PA, Rind D, Montori VM, Brito JP, Norris S, Elbarbary M, Post P, Nasser M, Shukla V, Jaeschke R, Brozek J, Djulbegovic B, Guyatt G: GRADE guidelines 15: Going from evidence to recommendation - determinants of a recommendation's direction and strength. J Clin Epidemiol, 2013; 66 (7): 726-735. : http://dx.doi.org/10.1016/j.jclinepi.2013.02.003
• Antes G, Augustin N, Beyersmann J, Caputo A, Falck-Ytter Y, Gerds T, Gerlach A, Graf E, Holländer N, Ihorst G, Lang B, Meier-Hirmer C, Musio M, Olschewski M, Roßner R, Sauerbrei W, Schlingmann J, Schmoor C, Schulgen G, Schulte Mönting J, Schwarzer G, Schumacher M: Freiburger Beiträge zur Biometrie und Klinischen Epidemiologie. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2004; 35: 74-122.
• Antes G, Dreier G, Hasselblatt H, Blümle A, Schumacher M: Register für klinische Studien - Einführung in das Thema und Hintergründe. Clinical trials registers - Introduction to the topic and backgrounds. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2009; 52: 459-462. : http://dx.doi.org/10.1007/s00103-009-0832-6
• Antes G, Lang B, Diener M: Das CONSORT-Statement. PM-Report, 2005; 12: 48-49.
• Arezzo A, Passera R, Salvai A, Arolfo S, Allaix ME, Schwarzer G, Morino M: Laparoscopy for rectal cancer is oncologically adequate: a systematic review and meta-analysis of the literature. Surg Endosc, 2015; 29: 334-348. : http://dx.doi.org/10.1007/s00464-014-3686-4
• Asbach S, Hartmann M, Wengenmayer T, Graf E, Bode C, Biermann J: Vector selection of a quadripolar left ventricular pacing lead affects acute hemodynamic response to cardiac resynchronization therapy: A randomized cross-over trial. Plos One, 2013; 8 (online): e67235. : http://dx.doi.org/10.1371/journal.pone.0067235
• Asbach S, Olschewski M, Faber TS, Zehender M, Bode C, Brunner M: Mortality in patients with atrial fibrillation has significantly decreased during the last three decades: 35 years of follow-up in 1627 pacemaker patients. Europace, 2008; 10: 391-394.
• Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O'Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer TT, Varonen H, Vist GE, Williams JW Jr, Zaza S, GRADE Working Group: Grading quality of evidence and strength of recommendations. Brit Med J, 2004; 328: 1490-1494.
• Att W, Yajima N-D, Wolkewitz M, Witkowski S, Strub JR: Influence of preparation and wall thickness on the resistance to fracture of zirconia implant abutments. Clin Implant Dent R, 2012; 14 Suppl. 1: e196-e203. : http://dx.doi.org/10.1111/j.1708-8208.2011.00428.x
• Augustin N, Sauerbrei W, Schumacher M: The practical utility of incorporating model selection uncertainty into prognostic models for survival data. Statistical Modelling, 2005; 5: 95-118.
• Augustin NH, Musio M, Wilpert von K, Kublin E, Wood SN, Schumacher M: Modeling spatiotemporal forest health monitoring data. J Am Stat Assoc, 2009; 104: 899-911. : http://dx.doi.org/10.1198/jasa.2009.ap07058
• Aumann K, Amann D, Gumpp V, Hauschke D, Kayser G, May AM, Wetterauer U, Werner M: Template-based synoptic reports improve the quality of pathology reports of prostatectomy specimens. Histopathology, 2012; 60: 634-644. : http://dx.doi.org/10.1111/j.1365-2559.2011.04119.x
• Aumann K, Frey A-V, May AM, Hauschke D, Kreutz C, Marx JP, Timmer J, Werner M, Pahl HL: Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates pre-fibrotic primary myelofibrosis from essential thrombocythemia. Blood, 2013; 122 (1): 93-99. : http://dx.doi.org/10.1182/blood-2012-11-463257
• Aumann K, Frey A-V, May AM, Hauschke D, Kreutz C, Marx JP, Timmer J, Werner M, Pahl HL: Differenzialdiagnose myelproliferativer Neoplasien. Pathologe, 2013; 34 Suppl. 2: 201-209. : http://dx.doi.org/10.1007/s00292-013-1824-8
• Aumann K, Kayser G, Amann D, Bronsert P, Hauschke D, Palade E, Passlick B, Werner M: The format type has impact on the quality of pathology reports of oncological lung resection specimens. Lung Cancer, 2013; 81: 382-387. : http://dx.doi.org/10.1016/j.lungcan.2013.05.017
• Aumann K, Lassmann S, Schöpflin A, May AM, Wöhrle FU, Zeiser R, Waller CF, Hauschke D, Werner M, Brummer T: The immunohistochemical staining pattern of Gab2 correlates with distinct stages of chronic myeloid leukemia. Hum Pathol, 2011; 42: 719-726. : http://dx.doi.org/10.1016/j.humpath.2010.09.012
• Auschill TM, Koch CA, Wolkewitz M, Hellwig E, Arweiler NB: Occurrence and causing stimuli of postoperative sensitivity in composite restorations. Oper Dent, 2009; 34: 3-10. : http://dx.doi.org/10.2341/08-7
• Baars JC, Ihorst G, Forster J, Frischer T, Karmaus W, Henschen M, Kühr J: Lungenfunktionsreferenzwerte im Schulalter. Pneumologie, 2001; 55: 72-78.
• Baghai M, Heilmann C, Beyersdorf F, Nakamura L, Geisen U, Olschewski M, Zieger B: Platelet dysfunction and acquired von Willebrand syndrome in patients with left ventricular assist devices. Eur J Cardio-thorac, 2015; 48: 421-427. : http://dx.doi.org/10.1093/ejcts/ezu510
• Barnett AG, Beyersmann J, Allignol A, Rosenthal VD, Graves N, Wolkewitz M: The time-dependent bias and its effect on extra length of stay due to nosocomial infection. Value Health, 2011; 14: 381-386. : http://dx.doi.org/10.1016/j.jval.2010.09.008
• Barrachina-Diez J M, Tashkandi E, Stampf S, Att W: Long-term outcome of one-piece implants. Part I: Implant characteristics and loading protocols. A systematic literature review with Meta-Analysis. Int J Oral Max Impl, 2013; 28: 503-518. : http://dx.doi.org/10.11607/jomi.2790
• Barrachina-Diez J M, Tashkandi E, Stampf S, Att W: Long-term Outcome of One-Piece Implants. Part II: Prosthetic Outcomes. A Systematic Literature Review with Meta-Analysis. Int J Oral Max Impl, 2013; 28: 1470-1482. (download: http://www.quintpub.com/journals/omi/fulltext.php?article_id=13721)
• Bateli M, Kern M, Wolkewitz M, Strub JR, Att W: A retrospective evaluation of teeth restored with zirconia ceramic posts: 10-year results. Clin Oral Invest, 2014; 18: 1181-1187. : http://dx.doi.org/10.1007/s00784-013-1065-5
• Batsford S, Brundiers M, Schweier O, Horbach E, Schulte Mönting J: Antibody to streptococcal cysteine proteinase as a seromarker of group A streptococcal (Streptococcus pyogenes) infections. Scand J Infect Dis, 2002; 34 (6): 407-412.
• Bauer R, Gottfriedsen G-U, Binder H, Dobmeier M, Cording C, Hajak G, Spiessl H: Burden of caregivers of patients with bipolar affective disorders. Am J Orthopsychiat, 2011; 81: 139-148. : http://dx.doi.org/10.1111/j.1939-0025.2010.01081.x
• Baumann T, Ludwig U, Pache G, Gall C, Saueressig U, Fisch D, Stankovic Z, Bartholomae J-P, Honal M, Bley TA, Langer M, Schaefer O: Detection of pulmonary nodules with move-during-scan magnetic resonance imaging using a free-breathing turbo inversion recovery magnitude sequence. Invest Radiol, 2008; 43: 359-367.
• Becker G, Allgaier H-P, Olschewski M, Zähringer A, Blum HE for the HECTOR Study Group: Long-acting octreotide versus placebo for treatment of advanced HCC: A randomized controlled double-blind study. Hepatology, 2007; 45: 9-15.
• Becker G, Dausch V, Xander C, Olschewski M, Momm F, Blum HE: Palliativmedizinische Inhalte in deutschsprachigen medizinischen Lehrbüchern Deut Med Wochenschr, 2007; 132: 256-260.
• Becker G, Hatami I, Xander C, Dworschak-Flach B, Olschewski M, Momm F, Deibert P, Higginson IJ, Blum HE: Palliative cancer care: An epidemiologic study. J Clin Oncol, 2011; 29: 646-650. : http://dx.doi.org/10.1200/JCO.2010.29.2599
• Becker G, Kempf DE, Xander CJ, Momm F, Olschewski M, Blum HE: Four minutes for a patient, twenty seconds for a relative - an observational study at a university hospital. Bmc Health Serv Res, 2010; 10 (online): 94. : http://dx.doi.org/10.1186/1472-6963-10-94
• Becker G, Sarhatlic R, Olschewski M, Xander C, Momm F, Blum HE: End-of-life care hospital: Current practice and potenials for improvement. J Pain Symptom Manag, 2007; 33: 711-719.
• Becker G, Soezgen T, Olschewski M, Laubenberger J, Blum HE, Allgaier H-P: Combined TACE and PEI for palliative treatment of unresectable hepatocellular carcinoma. World J Gastroentero, 2005; 11: 6104-6109.
• Behringer B, Pitako JA, Kunzmann R, Schmoor C, Behringer D, Mertelsmann R, Lübbert M: Prognosis of older patients with acute myeloid leukemia receiving either induction or noncurative treatment: a single-center retrospective study. Ann Hematol, 2003; 82: 381-389.
• Bender BU, Eng C, Olschewski M, Berger DP, Laubenberger J, Altehöfer C, Kirste G, Orszagh M, Veltenhoven van V, Miosczka H, Schmidt D, Neumann HPH: VHL c.505 T>C mutation confers a high age related penetrance but no increased overall mortality. J Med Genet, 2001; 38: 508-514.
• Bertz H, Spyridonidis A, Ihorst G, Engelhardt M, Grüllich C, Wäsch R, Marks R, Finke J: Marrow versus blood-derived stem cell grafts for allogeneic transplantation from unrelated donors in patients with active myeloid leukemia or myelodysplasia. Biol Blood Marrow Tr, 2012; 18: 894-902. : http://dx.doi.org/10.1016/j.bbmt.2011.11.017
• Beussel S, Hasenburg A, Bogatyreva L, Hauschke D, Werner M, Lassmann S: Aurora-B protein expression is linked to initial response to taxane-based first-line chemotherapy in stage III ovarian carcinoma. J Clin Pathol, 2012; 65: 29-35. : http://dx.doi.org/10.1136/jclinpath-2011-200212
• Beyersmann J, Dettenkofer M, Bertz H, Schumacher M: A competing risks analysis of bloodstream infection after stem-cell transplantation using subdistribution hazards and cause-specific hazards. Stat Med, 2007; 26: 5360-5369.
• Beyersmann J, Di Termini S, Pauly M: Weak Convergence of the Wild Bootstrap for the Aalen–Johansen Estimator of the Cumulative Incidence Function of a Competing Risk. Scand J Stat, 2013; 40 (3): 387-402. : http://dx.doi.org/10.1111/j.1467-9469.2012.00817.x
• Beyersmann J, Gastmeier P, Grundmann H, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infection. Infect Cont Hosp Ep, 2006; 27: 493-499.
• Beyersmann J, Gastmeier P, Grundmann H, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Transmission-associated nosocomial infections: Prolongation of intensive care unit stay and risk factor analysis using multistate models: Am J Infect Control, 2008; 36: 98-103.
• Beyersmann J, Gastmeier P, Schumacher M: Incidence in ICU populations: how to measure and report it? Intens Care Med, 2014; 40: 871-876. : http://dx.doi.org/10.1007/s00134-014-3279-7
• Beyersmann J, Gastmeier P, Wolkewitz M, Schumacher M: An easy mathematical proof showed that time-dependent bias inevitably leads to biased effect estimation. J Clin Epidemiol, 2008; 61: 1216-1221. : http://dx.doi.org/10.1016/j.jclinepi.2008.02.008
• Beyersmann J, Kneib T, Schumacher M, Gastmeier P: Nosocomial infection, length of stay, and time‐dependent bias. Infect Cont Hosp Ep, 2009; 30: 273-276. : http://dx.doi.org/10.1086/596020
• Beyersmann J, Latouche A, Buchholz A, Schumacher M: Simulating competing risks data in survival analysis. Stat Med, 2009; 8: 956-971. : http://dx.doi.org/10.1002/sim.3516
• Beyersmann J, Schumacher M: Time-dependent covariates in the proportional subdistribution hazards model for competing risks. Biostatistics, 2008; 9: 765-776. : http://dx.doi.org/10.1093/biostatistics/kxn009
• Beyersmann J, Schumacher M: A note on nonparametric quantile inference for competing risks and more complex multistate models. Biometrika, 2008; 95: 1006-1008. : http://dx.doi.org/10.1093/biomet/asn044
• Beyersmann J, Wolkewitz M, Allignol A, Grambauer N, Schumacher M: Application of multistate models in hospital epidemiology: Advances and challenges. Biometrical J, 2011; 53: 332-350. : http://dx.doi.org/10.1002/bimj.201000146
• Beyersmann J, Wolkewitz M, Schumacher M: The impact of time-dependent bias in proportional hazards modelling. Stat Med, 2008; 27: 6439-6454. : http://dx.doi.org/10.1002/sim.3437
• Bierbaum S, Forster J, Berner R, Rücker G, Rohde G, Neumann-Haefelin D, Panning M: Detection of respiratory viruses using a multiplex real-time PCR assay in Germany, 2009/10. Arch Virol, 2014; 159: 669-676. : http://dx.doi.org/10.1007/s00705-013-1876-3
• Bierbaum S, Konigsfeld N, Besazza N, Blessing K, Rücker G, Kontny U, Berner R, Schumacher M, Forster J, Falcone V, van de Sand C, Essig A, Huzly D, Rohde G, Neumann-Haefelin D, Panning M: Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study). Eur J Clin Microbiol, 2012; 31 (10): 2851-2861. : http://dx.doi.org/10.1007/s10096-012-1639-1
• Biewer ES, Zurn C, Arnold R, Glockler M, Schulte-Monting J, Schlensak C, Dittrich S: Chylothorax after surgery on congenital heart disease in newborns and infants -risk factors and efficacy of MCT-diet. J Cardiothorac Surg, 2010; 5 (online): 127. : http://dx.doi.org/10.1186/1749-8090-5-127
• Binder H, Allignol A, Schumacher M, Beyersmann J: Boosting for high-dimensional time-to-event data with competing risks. Bioinformatics, 2009; 25: 890-896. : http://dx.doi.org/10.1093/bioinformatics/btp088
• Binder H, Benner A, Bullinger L, Schumacher M: Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures. Stat Med, 2013; 32: 1778-1791. : http://dx.doi.org/10.1002/sim.5490
• Binder H, Müller T, Schwender H, Golka K, Steffens M, Hengstler JG, Ickstadt K, Schumacher M: Cluster-Localized Sparse Logistic Regression for SNP Data. Stat Appl Genet Mol, 2012; 11 (online). : http://dx.doi.org/10.1515/1544-6115.1694
• Binder H, Porzelius C, Schumacher M: An overview of techniques for linking high-dimensional molecular data to time-to-event endpoints by risk prediction models. Biometrical J, 2011; 53: 170-189. : http://dx.doi.org/10.1002/bimj.201000152
• Binder H, Schumacher M: Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models. Bmc Bioinformatics, 2008; 9: 10-19.
• Binder H, Schumacher M: Adapting prediction error estimates for biased complexity selection in high-dimensional bootstrap samples. Statistical Applications in Genetics and Molecular Biology, 2008; 7 (1) (online): Article 12. : http://www.bepress.com/sagmb/vol7/iss1/art12
• Binder H, Schumacher M: Comment on ‘network-constrained regularization and variable selection for analysis of genomic data’. Bioinformatics, 2008; 24: 2566-2568. : http://dx.doi.org/10.1093/bioinformatics/btn412
• Binder H, Schumacher M: Incorporating pathway information into boosting estimation of high-dimensional risk prediction models. Bmc Bioinformatics, 2009; 10 (1) (online): 18. : http://dx.doi.org/10.1186/1471-2105-10-18
• Binder L, Pieske B, Olschewski M, Geibel A, Klostermann B, Reiner C, Konstantinides S: N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation, 2005; 112: 1573-1579.
• Binder N, Schumacher M: Missing information caused by death leads to bias in relative risk estimates. J Clin Epidemiol, 2014; 67: 1111-1120. : http://dx.doi.org/10.1016/j.jclinepi.2014.05.010
• Blettner M, Sauerbrei W: Influence of model-building strategies on the results of a case- control study. Stat Med, 1993; 12: 1325-1338.
• Blettner M, Sauerbrei W: Metaanalysen epidemiologischer Studien Medizinische Klinik, 1998; 93: 442-445.
• Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T, Friedenreich C: Vergleich von traditionellen Reviews, Metaanalysen und gepoolten Analysen zur Bewertung von Risikofaktoren. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1997; 28: 148-166.
• Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T, Friedenreich C: Traditional reviews, meta-analyses and pooled analyses in epidemiology. International Journal of Epidemiology, 1999; 28: 1-9.
• Blettner M, Schlehofer B, Sauerbrei W: Grenzen von Metaanalysen aus publizierten Daten bei epidemiologischen Fragestellungen. Sozial- und Präventivmedizin, 1997; 42: 95-104.
• Blümle A, Antes G, Schumacher M, Just H, von Elm E: Clinical research projects at a German medical faculty: follow-up from ethical approval to publication and citation by others J Med Ethics, 2008; 34 (online): e20. : http://dx.doi.org/10.1136/jme.2008.024521
• Blümle A, Meerpohl JJ, Rücker G, Antes G, Schumacher M, von Elm E: Reporting of eligibility criteria of randomised trials: cohort study comparing trial protocols with subsequent articles. Brit Med J, 2011; 342 (online): d1828 . : http://dx.doi.org/10.1136/bmj.d1828
• Blümle A, Meerpohl JJ, Schumacher M, von Elm E: Fate of clinical research studies after ethical approval – follow-up of study protocols until publication. Plos One, 2014; 9 (online): e87184. : http://dx.doi.org/10.1371/journal.pone.0087184
• Boettler P, Hartmann M, Watzl K, Maroula E, Schulte Mönting J, Knirsch W, Dittrich S, Kececioglu D: Heart rate effect on strain and strain rate in healthy children. J Am Soc Echocardiog, 2005; 18: 1121-1130.
• Bohlius J, Herbst C, Reiser M, Schwarzer G, Engert A: Granulopoiesis-stimulating factors to prevent adverse effects in the treatment of malignant lymphoma. Cochrane Db Syst Rev, 2008; 4 (online): CD003189. : http://dx.doi.org/10.1002/14651858.CD003189.pub4
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• Sauerbrei W, Abrahamowicz M, Altman DG, le Cessie S, Carpenter J, and on behalf of the STRATOS initiative: STRengthening Analytical Thinking for Observational Studies: the STRATOS initiative. Stat Med, 2014; 33: 5413-5432. : http://dx.doi.org/10.1002/sim.6265
• Sauerbrei W, Bastert G, Bojar H, Beyerle C, Neumann RLA, Schmoor C, Schumacher M for the German, Breast Cancer Study Group: Randomized 2x2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients: An update based on 10 years' follow-up. J Clin Oncol, 2000; 18: 94-101.
• Sauerbrei W, Blettner M: Interpretation der Ergebnisse von 2×2-Tafeln: Teil 9 der Serie zur Bewertung wissenschaftlicher Publikationen. Interpreting Results in 2×2 Tables: Part 9 of a Series on Evaluation of Scientific Publications. Deutsches Ärzteblatt International, 2009; 106: 795-800. : http://dx.doi.org/10.3238/arztebl.2009.0795
• Sauerbrei W, Blettner M, Schmoor C, Bojar H, Schumacher M for the German, Breast Cancer Study Group: The effect of oral contraceptive use on the prognosis of node positive breast cancer patients. European Journal of Cancer, 1998; 34: 1348-1351.
• Sauerbrei W, Blettner M, Schumacher M: Letters Re: Meta-analysis comparing cisplatin total dose intensity and survifal: a critical reappraisal Gynecologic Oncology, 1996; 62: 427-429.
• Sauerbrei W, Blettner M, Schumacher M: The importance of basic statistical principles for the intepretation of epidemiological data Onkologie, 1997; 20: 455-460.
• Sauerbrei W, Graf E, Schumacher M: Randomisation und Patientenaufklärung. Notwendigkeit der Randomisation aus methodischer Sicht Onkologie, 1996; 19: 184-190.
• Sauerbrei W, Hübner K, Schmoor C, Schumacher M for the German, Breast Cancer Study Group: Validation of existing and development of new prognostic classification schemes in node negative breast cancer. Breast Cancer Research and Treatment, 1997; 42: 149-163.
• Sauerbrei W, Royston P, Bojar H, Schmoor C, Schumacher M and the German Br: Modelling the effects of standard prognostic factors in node-positive breast cancer. British Journal of Cancer, 1999; 79: 1752-1760.
• Sauerbrei W, Royston P, Look M: A new proposal for multivariable modelling of time-varying effects in survival data based on fractional polynomial time-transformation. Biometrical J, 2007; 49: 453-473.
• Sauerbrei W, Schmoor c, Schumacher M, for the GBSG: Identification of high and low risk groups in node negative breast cancer patients. Development and validation of indices. Breast Cancer Res Tr, 1993; 27: 139.
• Sauerbrei W, Schumacher M: A bootstrap resampling procedure for model building: Application to the Cox regression model. Stat Med, 1992; 11: 2093-2109.
• Sauerbrei W, Schumacher M: Basic statistical principles for the evaluation of risk factors. 8th International congress on the ultrasonic examination of the breast, Heidelberg, 1.-4.7.1993. Bildgebung - Imaging, 1993; 60: 5.
• Sauerbrei W, Schumacher M: Aspekte der statistischen Evaluation neuer Prognosefaktoren: Illustration bei Studien in der Onkologie. Geburtshilfe und Frauenheilkunde, 1999; 59: 483-487.
• Sauer R, Rauschecker HF, Schauer A, Schumacher M, Seegenschmiedt MH: Brusterhaltende Therapie des frühen Mammakarzinoms: vorlaäufige Ergebnisse der deutschen Brustkrebs-Studie-1. tagungsbericht 71. deutscher Röntgenkongreß, Karlsruhe 1990 Zentralblatt für Radiologie, 1990; 141: 351.
• Sauer R, Rauschecker HP, Gatzemeier W, Schumacher M, Sauerbrei W, Seegenschmiedt MH, Schauer A, Marx D: Therapy of small breast cancer - comparison between mastectomy and breast preserving therapy. International Journal Radiation Oncology Biol. Phys., 1991; 21 Suppl. 1: 129-130.
• Sauer R, Schauer A, Rauschecker HF, Schumacher M, Gatzemeier W, Sauerbrei W, Dunst J, Seegenschmiedt MH, Marx D, for the German Breast Cancer Study Group:: Breast preservation versus mastectomy in early breast cancer - 1991 update of the GBSG 1 - protocol and prognostic factors. Strahlentherapie und Onkologie, 1992; 168: 191-202.
• Sauer R, Schauer A, Rauschecker HF, Schumacher M, Gatzemeier W, Schmoor C, Dunst J, Seegenschmidt MH, Marx D: Therapy of small breast cancer: A prospective study on 1036 patients with special emphasis on prognostic factors. International Journal Radiation Oncology Biol. Phys., 1992; 23: 907-914.
• Schachinger V, Allert M, Kasper W, Just H, Vach W, Zeiher AM: Adjunctive intracoronary infusion of antithrombin III during percutaneous transluminal coronary angioplasty. Results of a prospective, randomized trial. Circulation, 1994; 90: 2258-2266.
• Schädel-Höpfner M, Windolf J, Antes G, Sauerland S, Diener MK: Evidence-based hand surgery: The role of cochrane reviews. J Hand Surg-eur Vol, 2008; 33: 110-117. : http://dx.doi.org/10.1177/1753193407087510
• Schäfer H, Berger J, Biebler K-E, Feldmann U, Greiser E, Jöckel K-H, Michaelis J, Neiss A, Raspe HH, Robra B-P, Schumacher M, Trampisch H-J, Victor N, Windeler J: Empfehlungen für die Erstellung von Studienprotokollen (Studienplänen) für klinische Studien. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1999; 30: 141-154.
• Schauer A, Korabiowska M, Kellner S, Schumacher M, Sauer R, Bojar H, Rauschecker H: Grading system for breast cancer. Anticancer Research, 1998; 18: 2139-2144.
• Schauer A, Marx D, Ummenhofer L, Rauschecker HF, Gatzemeier W, Sauer R, Schumacher M, Sauerbrei W: Die Multicenterstudie Kleines Mammakarzinom: Vorläufige Ergebnisse - Neue Aspekte. Deutsches Ärzteblatt, 1990; 87: C2125-C2130.
• Schempp CM, Winghofer B, Müller K, Schulte Mönting J, Mannel M, Schöpf E, Simon JC: Effect of oral administration of Hypericum perforatum extract (St. John's Wort) on skin erythema and pigmentation induced by UVB, UVA, visible light and solar simulated radiation. Phytother Res, 2003; 17: 141-146.
• Schimek-Jasch T, Troost EGC, Rücker G, Prokic V, Avlar M, Duncker-Rohr V, Mix M, Doll C, Grosu A-L, Nestle U: A teaching intervention in a contouring dummy run improved target volume delineation in locally advanced non-small cell lung cancer. Strahlenther Onkol, 2015; 191: 525-533. : http://dx.doi.org/10.1007/s00066-015-0812-8
• Schindler TH, Cadenas J, Facta AD, Li Y, Olschewski M, Sayre J, Goldin J, Schelbert HR: Improvement in coronary endothelial function is independently associated with a slowed progression of coronary artery calcification in type 2 diabetes mellitus. Eur Heart J, 2009; 30: 3064-3073. : http://dx.doi.org/10.1093/eurheartj/ehp482
• Schindler TH, Campisi R, Dorsey D, Prior JO, Olschewski M, Sayre J, Schelbert HR: Effect of hormone replacement therapy on vasomotor function of the coronary microcirculation in post-menopausal women with medically treated cardiovascular risk factors. Eur Heart J, 2009; 30: 978-986. : http://dx.doi.org/10.1093/eurheartj/ehp013
• Schindler TH, Hornig B, Buser PT, Olschewski M, Magosaki N, Pfisterer M, Nitzsche EU, Solzbach U, Just J: Prognostic value of abnormal vasoreactivity of epicardial coronary arteries to sympathetic stimulation in patients with normal coronary angiograms. Arterioscl Throm Vas, 2003; 23: 495-501.
• Schindler TH, Lewandowski E, Olschewski M, Hasler K, Solzbach U, Just H: Wirkung von Vitamin C auf die Thrombozytenaggregation bei Rauchern und Nichtrauchern. Med Klin, 2002; 97: 263-269.
• Schindler TH, Magosaki N, Jeserich M, Olschewski M, Nitzsche E, Holubarsch C, Solzbach U, Just H: Effect of ascorbic acid on endothelial dysfunction of epicardial coronary arteries in chronic smokers assessed by cold pressor testing. Cardiology, 2000; 94: 239-246.
• Schindler TH, Nitzsche E, Magosaki N, Brink I, Mix M, Olschewski M, Solzbach U, Just H: Regional myocardial perfusion defects during exercise, as assessed by three dimensional integration of morphology and function, in relation to abnormal endothelium dependent vasoreactivity of the coronary microcirculation. Heart, 2003; 89: 517-526.
• Schindler TH, Nitzsche EU, Munzel T, Olschewski M, Brink I, Jeserich M, Mix M, Buser PT, Pfisterer M, Solzbach U, Just H: Coronary vasoregulation in patients with various risk factors in response to cold pressor testing. J Am Coll Cardiol, 2003; 42: 814-822.
• Schindler TH, Nitzsche EU, Olschewski M, Brink I, Mix M, Prior J, Facta A, Inubushi M, Just H, Schelbert H: PET-measured responses of MBF to cold pressor testing correlate with indices of coronary vasomotion on quantitative coronary angiography. J Nucl Med, 2004; 45: 419-428.
• Schindler TH, Nitzsche EU, Olschewski M, Magosaki N, Mix M, Prior JO, Facta AD, Solzbach U, Just H, Schelbert HR: Chronic inflammation and impaired coronary vasoreactivity in patients with coronary risk factors. Circulation, 2004; 110: 1069-1075.
• Schindler TH, Nitzsche EU, Schelbert HR, Olschewski M, Sayre J, Mix M, Brink I, Zhang X-L, Kreissl M, Magosaki N, Just H, Solzbach U: Positron emission tomography-measured abnormal responses of myocardial blood flow to sympathetic stimulation are associated with the risk of developing cardiovascular events. J Am Coll Cardiol, 2005; 45: 1505-1512.
• Schmidt B, Brunner M, Olschewski M, Hummel C, Faber TS, Grom A, Giesler U, Bode C, Zehender M: Pacemaker therapy in very elderly patients: Long-term survival and prognostic parameters. Am Heart J, 2003; 146: 908-913.
• Schmidt DP, Schulte Mönting J, Schumacher M: Prognosis of central retinal artery occlusion: Local intraarterial fibrinolysis versus conservative treatment. Am J Neuroradiol, 2002; 23 (8): 1301-1307.
• Schmidt-Trucksass A, Cheng DC, Sandrock M, Schulte-Monting J, Rauramaa R, Huonker M, Burkhardt H: Computerized analysing system using the active contour in ultrasound measurement of carotid artery intima-media thickness. Clin Physiol, 2001; 21 (5): 561-569.
• Schmitt-Graeff A, Ertelt-Heitzmann V, Allgaier H-P, Olschewski M, Nitschke R, Haxelmans S, Koelble K, Behrens J, Blum HE: Coordinated expression of cyclin D1 and LEF-1/TCF transcription factor is restricted to a subset of hepatocellular carcinoma. Liver Int, 2005; 25: 839-847.
• Schmitt-Graeff A, Koeninger A, Olschewski M, Haxelmans S, Nitschke R, Bochaton-Piallat M-L, Lifschitz-Mercer B, Gabbiani G, Langbein L, Czernobilsky B: The Ki67+ proliferation index correlates with increased cellular retinol-binding protein-1 and the coordinated loss of plakophilin-1 and desmoplakin during progression of cervical squamous lesions. Histopathology, 2007; 51: 87-97.
• Schmitt-Graeff AH, Teo S-S, Olschewski M, Schaub F, Haxelmans S, Kirn A, Reinecke P, Germing U, Skoda RC: JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Haematol-hematol J, 2008; 93: 34-40.
• Schmitt-Gräff A, Ertelt V, Allgaier H-P, Koelble K, Olschewski M, Nitschke R, Bochaton-Piallat M-L, Gabbiani G, Blum HE: Cellular retinol-binding protein-1 in hepatocellular carcinoma correlates with beta-catenin, Ki67 index, and patient survival. Hepatology, 2003; 38: 471-480.
• Schmoor, C, Sauerbrei, W, Schumacher, M: Sample size considerations for the evaluation of prognostic factors in survival analysis Stat Med, 2000; 19: 441-452.
• Schmoor C, Bastert G, Dunst J, Bojar H, Christmann D, Unbehaun V, Tümmers G, Bauer W, Sauerbrei W, Schumacher M for the German Breast Cancer Study Group: Randomized trial on the effect of radiotherapy in addition to 6 cycles of CMF in node positive breast cancer patients Int J Cancer, 2000; 86: 408-415.
• Schmoor C, Caputo A, Schumacher M: Evidence from nonrandomized studies: A case study on the estimation of causal effects. Am J Epidemiol, 2008; 167: 1120-1129.
• Schmoor C, Eisele C, Graf E, Sauerbrei W, Klingele B, Hellmer A, Rossner R, Schumacher M: Arbeitsweisen des Methodischen Zentrums am Institut für Medizinische Biometrie und Medizinische Informatik der Universität Freiburg bei der biometrischen Betreuung klinischer Studien Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 1997; 28: 253-274.
• Schmoor C, Olschewski M, Sauerbrei W, Schumacher M: Long-term follow-up of patients in four prospective studies of the German Breast Cancer Study Group (GBSG): A summary of key results. Onkologie, 2002; 25: 143-150.
• Schmoor C, Olschewski M, Schumacher M: Randomized and non-randomized patients in clinical trials: experiences with comprehensive cohort studies Statistics in Medicine, 1996; 15: 263-271.
• Schmoor C, Sauerbrei W, Baster G, Schumacher M for the German, Breast Cancer Study Group, (GBSG): Role of isolated locoregional recurrence of breast cancer: results of four prospective studies. Journal of Clinical Oncology, 2000; 18: 1696-1708.
• Schmoor C, Sauerbrei W, Bastert G, Bojar H, Schumacher M for the German Breast Cancer Study Group (GBSG): Long-term prognosis of breast cancer patients with 10 or more positive lymph nodes treated with CMF. Eur J Cancer, 2001; 37: 1123-1131.
• Schmoor C, Schumacher M: Adaptive statistical procedures for the analysis of nonmonotone dose-response relationships. Biometrie und Informatik in Medizin und Biologie, 1992; 23: 113-126.
• Schmoor C, Schumacher M: High-dose chemotherapy as adjuvant treatment for breast cancer - some statistical arguments Onkologie, 1996; 19: 78-80.
• Schmoor C, Schumacher M: Effects of covariate omission and categorization when analysing randomized trials with the Cox model. Statistics in Medicine, 1997; 16: 225-237.
• Schmoor C, Schumacher M: Methodological arguments for the necessity of randomized trials in high-dose chemotherapy for breast cancer. Breast Cancer Research and Treatment, 1999; 54: 31-38.
• Schmoor C, Schumacher M, Finke J, Beyersmann J: Competing risks and multistate models. Clin Cancer Res, 2013; 19: 12-21. : http://dx.doi.org/10.1158/1078-0432.CCR-12-1619
• Schmoor C, Ulm K, Schumacher M: Comparison of the Cox-model anf the regression tree procedure in analyzing a randomized clinical trial. Stat Med, 1993; 12: 2351-2366.
• Schmucker C, Antes G, Lelgemann M: Position paper: The need for head-to-head studies comparing Avastin versus Lucentis. Surv Ophthalmol, 2009; 54: 70-707. : http://dx.doi.org/doi:10.1016/j.survophthal.2009.08.002
• Schmucker C, Bluemle A, Briel M, Portalupi S, Lang B, Motschall E, Schwarzer G, Bassler D, Mueller KF, von Elm E, Meerpohl JJ, on behalf of the OPEN Consortium: A protocol for a systematic review on the impact of unpublished studies and studies published in the gray literature in meta-analyses. Systematic Reviews, 2013; 2 (online): 24. : http://dx.doi.org/10.1186/2046-4053-2-24
• Schmucker C, Ehlken C, Agostini HT, Antes G, Ruecker G, Lelgemann M, Loke YK: A Safety Review and Meta-Analyses of Bevacizumab and Ranibizumab: Off-Label versus Goldstandard. Plos One, 2012; 7 (online): e42701. : http://dx.doi.org/10.1371/journal.pone.0042701
• Schmucker C, Ehlken C, Hanse LL, Antes G, Agostini HT, Lelgemann M: Intravitreal bevacizumab (Avastin) vs. ranibizumab (Lucentis) for the treatment of age-related macular degeneration: a systematic review. Curr Opin Ophthalmol, 2010; 21: 218-226. : http://dx.doi.org/10.1097/ICU.0b013e3283386783
• Schmucker C, Loke YK, Ehlken C, Agostini HT, Hansen LL, Antes G, Lelgemann M: Intravitreal bevacizumab (Avastin) versus ranibizumab (Lucentis) for the treatment of age-related macular degeneration: a safety review. Brit J Ophthalmol, 2011; 95: 308-317. : http://dx.doi.org/10.1136/bjo.2009.178574
• Schneck J, Fagot J-P, Sekula P, Sassolas B, Roujeau JC, Mockenhaupt M: Effects of treatments on the mortality of Stevens-Johnson syndrome and toxic epidermal necrolysis: A retrospective study on patients included in the prospective EuroSCAR Study. J Am Acad Dermatol, 2008; 58: 33-40.
• Schoenthaler M, Miernik A, Offner K, Karcz WK, Hauschke D, Sevcenco S, Kuehhas FE, Bach C, Buchholz N, Wilhelm K: The cumulative analgesic consumption score (CACS): evaluation of a new score to describe postsurgical analgesic consumption as a surrogate parameter for postoperative pain and invasiveness of surgical procedures. Int Braz J Urol, 2014; 40: 330-336. : http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.03.06
• Schoop R, Beyersmann J, Schumacher M, Binder H: Quantifying the predictive accuracy of time-to-event models in the presence of competing risks. Biometrical J, 2011; 53: 88-112. : http://dx.doi.org/10.1002/bimj.201000073
• Schoop R, Graf E, Schumacher M: Quantifying the predictive performance of prognostic models for censored survival data with time-dependent covariates. Biometrics, 2008; 64: 603-610.
• Schoop R, Schumacher M, Graf E: Measures of prediction error for survival data with longitudinal covariates. Biometrical J, 2011; 53: 275-293. : http://dx.doi.org/10.1002/bimj.201000145
• Schreyer AG, Gölder S, Scheibl K, Volk M, Lenhart M, Timmer A, Scholmerich J, Feuerbach S, Rogler G, Herfarth H, Seitz J: Dark lumen magnetic resonance enteroclysis in combination with MRI colonography for whole bowel assessment in patients with Crohn's disease: first clinical experience. Inflamm Bowel Dis, 2005; 11: 388-394.
• Schröder T, Schumacher M: Graphical aids for the analysis of drug cumulation and deviations from planned treatment schedule in cyclic chemotherapy Onkologie, 1997; 20: 113-116.
• Schuler P, Assefa D, Basler N, Olschewski M, Ahrens I, Nordt T, Bode C, Peter K: Adhesion of monocytes to medical steel as used for vascular stents is mediated by the integrin receptor Mac-1 (CD11b/CD18; alphaM beta2) and can be inhibited by semiconductor coating. Cell Commun Adhes, 2003; 10: 17-26.
• Schulgen G, Kropec A, Kappstein I, Daschner F, Schumacher M: Estimation of extra hospital stay attributable to nosocomial infections: heterogeneity and timing of events J Clin Epidemiol, 2000; 53: 409-417.
• Schulgen G, Lausen B, Olsen J, Schumacher M: Outcome-oriented cutpoints in analysis of quantitative exposures. American Journal of Epidemiology, 1994; 140: 172-184.
• Schulgen G, Olschewski M, Krane V, Wanner C, Ruf G, Schumacher M: Sample sizes for clinical trials with time-to-event endpoints and competing risks. Contemp Clin Trials, 2005; 26: 386-395.
• Schulgen G, Schmoor C, Sauerbrei W, Schumacher M: A note on estimating local recurrence rates in clinical trials on the treatment of breast cancer Breast Cancer Research and Treatment, 1998; 49: 87-91.
• Schulgen G, Schumacher M: Estimation of prolongation of hospital stay attributable to nosocomial infections: New approaches based on multistate models Lifetime Data Analysis, 1996; 2: 219-240.
• Schulz H, Bohlius JF, Trelle S, Skoetz N, Reiser M, Kober T, Schwarzer G, Herold M, Dreyling M, Hallek M, Engert A: Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis. J Natl Cancer I, 2007; 99: 706-714.
• Schumacher M: Evaluation of nonproportional treatment effects in cancer clinical trials. Cancer Invest, 1990; 8: 91-98.
• Schumacher M: Methodische Grundlagen klinischer Forschung - Reminiszenzen an Herbert Immich und seine Beiträge zur Medizinischen Statistik. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2004; 35: 44-53.
• Schumacher M: Wie die Medizinische Statistik nach Freiburg kam. - Eine historische Perspektive. GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005; 1 (2): DOC-07.
• Schumacher M, Allignol A, Beyersmann J, Binder N, Wolkewitz M: Hospital-acquired infections—appropriate statistical treatment is urgently needed! Int J Epidemiol, 2013; 42: 1502-1508. : http://dx.doi.org/10.1093/ije/dyt111
• Schumacher M, Bastert G, Bojar H, Hübner K, Olschewski M, Sauerbrei W, Schmoor C., Beyerle C., Neumann R.L.A., Rauschecker H.F. for the Germ, Cancer Study Group (GBSG): Randomized 2x2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients. Journal of Clinical Oncology, 1994; 12: 2086-2093.
• Schumacher M, Bastert G, Bojar H, Hübner K, Sauerbrei W, Schmoor C, Olschewski M, for the German Breast Cancer Study Group: A randomized clinical trial evaluating the duration of chemotherapy in patients with primary, node-positive breast cancer. The Breast, 1993; 2: 194.
• Schumacher M, Beck M, Roßner R: European Cancer Clinical Trial Register (ECCTR) - eine aktuelle, europaweite Informationsquelle über Theapiestudien in der Onkologie Forum DKG, 1996; 11: 220-223.
• Schumacher M, Binder H, Gerds T: Assessment of survival prediction models based on microarray data. Bioinformatics, 2007; 23: 1768-1774.
• Schumacher M, Graf E, Gerds T: How to assess prognostic models for survival data: a case study in oncology. Method Inform Med, 2003; 42: 564-571.
• Schumacher M, Holländer N, Sauerbrei W: Resampling and cross-validation techniques: A tool to reduce bias caused by model building? Statistics in Medicine, 1997; 16: 2813-2827.
• Schumacher M, Olschewski M: Statistical analysis of quality of life data in cancer clinical trials. Stat Med, 1990; 9: 749-763.
• Schumacher M, Olschewski M, Sauerbrei W: On the importance of controlled clinical trials in oncology. Journal of Cancer Research and Clinical Oncology, 1992; 118: R 159.
• Schumacher M, Olschewski M, Schulgen G: Assessment of quality of life in clinical trials. Stat Med, 1991; 10: 1915-1930.
• Schumacher M, Roßner R, Vach W: Neural networks and logistic regression: Part I Computational Statistics & Data Analysis, 1996; 21: 661-682.
• Schumacher M, Sauerbrei W, Schmoor C: Prognostische Faktoren in den GBSG-Mammakarzinomstudien I-III. Zentralblatt Radiologie, 1993; 147: 793.
• Schumacher M, Schmidt D, Jurklies B, Gall C, Wanke I, Schmoor C, Maier-Lenz H, Solymosi L, Brueckmann H, Neubauer AS, Wolf A, Feltgen N, and EAGLE-Study Group: Central retinal artery occlusion: Local intra-arterial fibrinolysis versus conservative treatment, a multicenter randomized trial. Ophthalmology, 2010; 117: 1367-1375. : http://dx.doi.org/10.1016/j.ophtha.2010.03.061
• Schumacher M, Schmoor C, Plog A, Schwarzwald R, Taschner Ch, Echternach M, Richter B, Spahn C: Motor functions in trumpet playing-a real-time MRI analysis. Neuroradiology, 2013; 55 (9): 1171-1181. : http://dx.doi.org/10.1007/s00234-013-1218-x
• Schumacher M, Schmoor C, Sauerbrei W, Schauer A, Umenhofer L, Gatzemeier W, Rauschecker HF: The prognostic effect of histological tumor grade in node-negative breast cancer patients. Breast Cancer Res Tr, 1993; 25: 235-245.
• Schumacher M, Schmoor C, Sauerbrei W, Schauer A, Umenhofer L, Gatzemeier W, Rauschecker HF, fot the German Breast Cancer Study Group (GBSG): The prognostic effect of histological tumor grade in noce-negative breast cancer patients. The Breast, 1993; 2: 205.
• Schumacher M, Schulte Mönting J, Stoeter P, Warmuth-Metz M, Sloymosi L: Magnetic resonance imaging compared with biopsy in the diagnosis of brainstem diseases of childhood: a multicenter review. J Neurosurg, 2007; 106 Suppl. 2: 111-119.
• Schumacher M, Wangler M, Wolkewitz M, Beyersmann J: Attributable mortality due to nosocomial infections - A simple and useful application of multistate models. Method Inform Med, 2007; 46: 595-600.
• Schumacher Y O, Wenning M, Robinson N, Sottas P-E, Ruecker G, Pottgiesser T: Diurnal and exercise-related variability of haemoglobin and reticulocytes in athletes . Int J Sports Med, 2010; 31: 225-230. : http://dx.doi.org/10.1055/s-0029-1243617
• Schünemann HJ, Langer G, Meerpohl JJ, Ollenschläger G, Perleth M: Das GRADE-System: Ein Prolog zur Artikelserie in der ZEFQ. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen, 2012; 106: 354-356. : http://dx.doi.org/10.1016/j.zefq.2012.05.016
• Schünemann HJ, Wiercioch W, Etxeandia I, Falavigna M, Santesso N, Mustafa R, Ventresca M, Brignardello-Petersen R, Laisaar KT, Kowalski S, Baldeh T, Zhang Y, Raid U, Neumann I, Norris SL, Thornton J, Harbour R, Treweek S, Guyatt G, Alonso-Coello P, Reinap M, Brozek J, Oxman A, Akl EA: Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. Can Med Assoc J, 2014; 186 (3): E123-E142. : http://dx.doi.org/10.1503/cmaj.131237
• Schwacha H, Allgaier H-P, Deibert P, Olschewski M, Allgaier U, Blum HE: A sphincterotome-based technique for selective transpapillary common bile duct cannulation Gastrointest Endosc, 2000; 52 (3): 387-391.
• Schwarzer G, Antes G, Schumacher M: Inflation of type I error rate in two statistical tests for the detection of publication bias in meta-analyses with binary outcomes. Stat Med, 2002; 21: 2465-2477.
• Schwarzer G, Antes G, Schumacher M: A test for publication bias in meta-analysis with sparse binary data. Stat Med, 2007; 26: 721-733.
• Schwarzer G, Galandi D, Antes G, Schumacher M: Meta-Analyse randomisierter klinischer Studien, Publikations-Bias und Evidence-Based Medicine (EBM) Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2000; 31: 1-21.
• Schwarzer G, Nagata T, Mattern D, Schmelzeisen R, Schumacher M: Comparison of fuzzy inference, logistic regression, and classification trees (CART) for the prediction of cervical lymph node metastasis in carcinoma of the tongue. Method Inform Med, 2003; 42 (5): 572-577.
• Schwarzer G, Schumacher M: Statistische Tests zum Vergleich zweier Behandlungsmethoden. Klassisches Testverfahren oder Äquivalenztest? Nervenheilkunde, 1997; 16: 442-446.
• Schwarzer G, Schumacher M: Artificial neural networks for diagnosis and prognosis in prostate cancer. Seminars in Urologic Oncology, 2002; 20 (2): 89-95.
• Schwarzer G, Schumacher M, Maurer TB, Ochsner PE: Statistical analysis of failure times in total joint replacement. J Clin Epidemiol, 2001; 54: 997-1003.
• Schwarzer G, Vach W, Schumacher M: On the misuses of artificial neural networks for prognostic and diagnostic classification in oncology Stat Med, 2000; 19: 541-561.
• Seegenschmiedt M, Sauerbrei W, Sauer R, for the Gerrman Breast Study Group (GBSG): Schumacher M, Schauer A, Rauschecker HF, for participating institutions within the GBSG: Dinkloh H, Dühmke E, Haase KD, Haase W, Heisen E, Heinze HG, Janik I, Szepesi S: Quality control review for radiotherapy of small breast cancer: Analysis of 708 patients in the GBSG 1 trial. Stahlentherapie und Onkologie, 1993; 6: 339-350.
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• Wolkewitz M, Allignol A, Harbarth S, de Angelis G, Schumacher M, Beyersmann J: Time-dependent study entries and exposures in cohort studies can easily be sources of different and avoidable types of bias. J Clin Epidemiol, 2012; 65: 1171-1180. : http://dx.doi.org/10.1016/j.jclinepi.2012.04.008
• Wolkewitz M, Allignol A, Schumacher M, Beyersmann J: Two pitfalls in survival analyses of time-dependent exposure: a case study in a cohort of Oscar Nominees. Am Stat, 2010; 64: 205-211. : http://dx.doi.org/10.1198/tast.2010.08259
• Wolkewitz M, Barnett AG, Palomar Martinez M, Frank U, Schumacher M, IMPLEMENT Study Group: Interventions to control nosocomial infections: study designs and statistical issues. J Hosp Infect, 2014; 86: 77-82. : http://dx.doi.org/10.1016/j.jhin.2013.09.015
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Modeling the effect of time-dependent exposure on intensive care unit mortality. Intens Care Med, 2009; 35: 826-832. : http://dx.doi.org/10.1007/s00134-009-1423-6
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Efficient risk set sampling when a time-dependent exposure is present. Matching for time to exposure versus exposure density sampling. Method Inform Med, 2009; 48: 438-443. : http://dx.doi.org/10.3414/ME9241
• Wolkewitz M, Beyersmann J, Schumacher M: A note on statistical association and causality derived from epidemiological ICU data. Intens Care Med, 2010; 36: 549. : http://dx.doi.org/10.1007/s00134-009-1721-z
• Wolkewitz M, Bruckner T, Schumacher M: Accurate variance estimation for prevalence ratios. Method Inform Med, 2007; 46: 567-571.
• Wolkewitz M, Cooper B, Barnett AG, Binder N, Schumacher M: Treatment of hospital-acquired pneumonia. Lancet Infect Dis, 2011; 11: 729. : http://dx.doi.org/10.1016/S1473-3099(11)70262-6
• Wolkewitz M, Cooper B, Palomar-Martinez M, Olaechea-Astigarraga P, Alvarez-Lerma F, Schumacher M: Nested case-control studies in cohorts with competing events. Epidemiology, 2014; 25: 122-125. : http://dx.doi.org/10.1097/EDE.0000000000000029
• Wolkewitz M, Cooper BS, Bonten MJM, Barnett AG, Schumacher M: Interpreting and comparing risks in the presence of competing events. Bmj-brit Med J, 2014; 349 (online): g5060. : http://dx.doi.org/10.1136/bmj.g5060
• Wolkewitz M, Cooper BS, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Barnett AG, Harbarth S, Schumacher M: Multilevel competing risk models to evaluate the risk of nosocomial infection. Crit Care, 2014; 18 (online): R64. : http://dx.doi.org/10.1186/cc13821
• Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Environmental contamination as an important route for the transmission of the hospital pathogen VRE: Modeling and prediction of classical interventions. Infectious Diseases: Research and Treatment, 2008; 1: 3-11.
• Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Statistical epidemic modeling with hospital outbreak data. Stat Med, 2008; 27: 6522-6531. : http://dx.doi.org/10.1002/sim.3419
• Wolkewitz M, Frank U, Philips G, Schumacher M, Davey P, on behalf of the BURDEN study group†: Mortality associated with in-hospital bacteraemia caused by Staphylococcus aureus: a multistate analysis with follow-up beyond hospital discharge. J Antimicrob Chemoth, 2011; 66: 381-386. : http://dx.doi.org/10.1093/jac/dkq424
• Wolkewitz M, Rothebacher D, Low M, Stegmaier C, Ziegler H, Radulescu M, Brenner H, Diepgen TL: Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly subjects: results of the ESTHER study. Brit J Dermatol, 2007; 156: 693-697.
• Wolkewitz M, Schumacher M: Simulating and analysing infectious disease data in a heterogeneous population with migration. Comput Meth Prog Bio, 2011; 104: 29-36. : http://dx.doi.org/10.1016/j.cmpb.2010.05.007
• Wolkewitz M, Vonberg RP, Grundmann H, Beyersmann J, Gastmeier P, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care, 2008; 12 (online): R44. : http://dx.doi.org/10.1186/cc6852
• Württemberger G, Olschewski M, Zielinski J, sliwinski P, Auw-Haedrich C, Klein G, Matthys H: Determinanten des Akut- und Langzeiterfolges einer antiarrhytmischen Therapie mit Klasse-I-Substanzen. Zeitschrift für Kardiologie, 1990; 79: 154.
• Zander AR, Kröger N, Schmoor C, Krüger W, Möbus V, Frickhofen N, Metzner B, Schultze W, Berdel WE, Köenigsmann M, Thiel E, Wandt H, Possinger K, Trümer L, Kreienberg R, Carstensen M, Schmidt EH, Jänicke F, Schumacher M, Jonat W: High-dose chemotherapy with autologous hematopoietic stem-cell support compared with standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: First results of a randomized trial. J Clin Oncol, 2004; 22: 2273-2283.
• Zander AR, Schmoor C, Kröger N, Krüger W, Möbus V, Frickhofen N, Metzner B, Berdel WE, Koenigsmann M, Thiel E, Wandt H, Possinger K, Kreienberg R, Schumacher M, Jonat W: Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up. Ann Oncol, 2008; 19: 1082-1089.
• Zehender M, Furtwängler A, Hohnloser S, Eppinger S, Olschewski M, Meinertz T, Just H: Loss of efficacy, proarrhytmic agents - multivariate regression analysis. J Am Coll Cardiol, 1992; 19: 386 A.
• Zehender M, Furtwängler A, Hohnloser S, Eppinger S, Olschewski M, Meinertz T, Just H: Loss of efficacy, proarrhythmia and side effects during longterm therapy with 3 class I antiarrhythmic agents - multivariate regression analysis. Eur Heart J, 1992; 13: 209.
• Zehender M, Hohnloser S, Geibel A, Furtwängler A, Olschewski M, Meinertz T, Just H: Short-term and long-term treatment with propaphenone: determinants of arrhythmia supression, persistence of efficacy, arrhythmogegesis, and side effects in patients with symptoms. British Heart Journal, 1992; 67: 491-497.
• Zehender M, Kasper W, Kauder E, Geibel A, Schönthaler M, Olschewski M, Just H: Eligibility for and benefit of thrombolytic therapy in inferior myocardial infarction - focus on the prognostic importance of right ventricular infarction. Journal of the American College of Cardiology, 1994; 24: 362-369.
• Zehender M, Kasper W, Kauder E, Schönthaler M, Geibel A, Olschewski M, Just H: Right ventricular infarction as an independent predictor of prognosis after acute inferior myocardial infarction. New Engl J Med, 1993; 328: 981-988.
• Zehender M, Kasper W, Kauder E, Schönthaler M, Geibel A, Olschewski M, Just H: Der akute rechtsventrikuläre Myokardinfarkt. Neue diagnostische und therapeutische Ansätze bei einem prognostisch ungünstigen Krankheitsbild. Medizinische Klinik, 1994; 89: 351-359.
• Zehender M, Kasper W, Kauder E, Schönthaler M, Olschewski M, Just H: Comparison of the diagnostic accuracy, time dependency and prognostic impact of abnormal Q waves, combined ECG Criteria and ST-segment abnormalities commonly used to evidence right ventricular infarction. British Heart Journal, 1994; 72: 119-124.
• Zehender M, Kasper W, Krause Th, Granzow H, Olschewski M, Moser E, Just H: Prevalence, characteristics, and risk stratification of electrocardiographic and symptomatic silence of myocardial ischemia despite scintigraphically, evidenced ischemia in symptomatic patients presenting with severe coronary artery stenosis. Clinical Cardiology, 1995; 18: 150-156.
• Zehender M, Kasper W, Schönthaler M, Kauder E, Olschewski M, Just H: Thrombolytische Therapie bei akutem Hinterwandinfarkt - prognostische Bedeutung einer rechtsventrikulären Infarktbeteiligung. Zeitschrift für Kardiologie, 1992; 81: 49.
• Zehender M, Kasper W, Schönthaler M, Krause T, Kauder E, Olschewski M, Just H: Prognostic impact of five diagnostic strategies predicting brady- and tachyarrhythmic complications due to right ventricular infarction complicating acute inferior mycoardial infarction. British Heart Journal, 1994; 15: 414.
• Zehender M, Kasper W, Schönthaler M, Olschewski M, Just H: Thrombolytic therapy in acute inferior myocardial infarction - Importance of right ventricular involvement to improve prognosis. Intens Care Med, 1992; 18: 116.
• Zehender M, Kasper W, Schönthaler M, Olschewski M, Just H: Thrombolytische Therapie bei akutem Hinterwandinfarkt - Prognostische Bedeutung einer rechtsventrikulären Infarktbeteiligung. Intensivmedizin, 1992; 29: 382.
• Zehender M, Meinertz T, Hohnloser S, Geibel A, Gerisch U, Olschewski M, Just H: Prevalence of circadian variations and spontaneous variability of cardiac disorders and ECG changes suggestive of myocardial ischemia in systemic arterial hypertension. Circulation, 1992; 85: 1808-1815.
• Zehender M, Schönthaler M, Olschewski M: Right ventricular infarction - A strong, independent prognostic parameter for life-threatening tachyarrhythmias and AV block after acute inferior myocardial infarction. Circulation, 1992; 86: 454.
• Zeiser R, Burchert A, Lengerke C, Verbeek M, Maas-Bauer K, Metzelder SK, Spoerl S, Ditschkowski M, Ecsedi M, Sockel K, Ayuk F, Ajib S, de Fontbrune FS, Na I-K, Penter L, Holtick U, Wolf D, Schuler E, Meyer E, Apostolova P, Bertz H, Marks R, Lübbert M, Wäsch R, Scheid C, Stölzel F, Ordemann R, Bug G, Kobbe G, Negrin R, Brune M, Spyridonidis A, Schmitt-Gräff A, van der Velden W, Huls G, Mielke S, Grigoleit GU, Kuball J, Flynn R, Ihorst G, Du J, Blazar BR, Arnold R, Kröger N, Passweg J, Halter J, Socié G, Beelen D, Peschel C, Neubauer A, Finke J, Duyster J, von Bubnoff N: Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey. Leukemia, 2015; 29: 2062-2068. : http://dx.doi.org/10.1038/leu.2015.212
• Zeiser R, Burger JA, Bley TA, Windfuhr-Blum M, Schulte Mönting J, Behringer D: Clinical follow-up indicates differential accuracy of magnetic resonance imaging and immuncytology of the cerebral spinal fluid for the diagnosis of neoplastic meningitis - single centre experience. Brit J Haematol, 2004; 124: 762-768.
• Zhao M, Stampf S, Valina C, Kienzle R-P, Ferenc M, Gick M, Essang E, Nührenberg T, Büttner HJ, Schumacher M, Neumann F-J: Role of euroSCORE II in predicting long-term outcome after percutaneous catheter intervention for coronary triple vessel disease or left main stenosis. Int J Cardiol, 2013; 168 (4): 3273-3279. : http://dx.doi.org/10.1016/j.ijcard.2013.04.136
• Zlei M, Egert S, Wider D, Ihorst G, Wasch R, Engelhardt M: Characterization of in vitro growth of multiple myeloma cells. Exp Hematol, 2007; 35: 1550-1561.
• Zocher M, Czub S, Schulte Mönting J, Torre de la JC, Sauder C: Alterations in neurotrophin and neurothrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. J Neurovirol, 2000; 6: 462-477.
• Zuschneid I, Geffers C, Sohr D, Kohlhase C, Schumacher M, Rüden H, Gastmeier P: Validation of surveillance in the intensive care unit component of the German Nosocomial Infections Surveillance System. Infection Control and Hospital Epidemiology, 2007; 28: 496-499.
• Zuschneid I, Rücker G, Schoop R, Beyersmann J, Schumacher M, Geffers C, Rüden H, Gastmeier P: Representativeness of the surveillance data in the intensive care unit component of the German Nosocomial Infections Surveillance System. Infect Cont Hosp Ep, 2010; 31: 934-938. : http://dx.doi.org/10.1086/655462

• Brożek JL, Akl EA, Compalati E, Kreis J, Terracciano L, Fiocchi A, Ueffing E, Andrews J, Alonso-Coello P, Meerpohl JJ, Lang DM, Jaeschke R, Williams JW Jr, Phillips B, Lethaby A, Bossuyt P, Glasziou P, Helfand M, Watine J, Afilalo M, Welch V, Montedori A, Abraha I, Horvath AR, Bousquet J, Guyatt GH, Schünemann HJ, for the GRADE Working Group: Grading quality of evidence and strength of recommendations in clinical practice guidelines Part 3 of 3. The GRADE approach to developing recommendations. Allergy, 2011; 66: 588-595. : http://dx.doi.org/10.1111/j.1398-9995.2010.02530.x
• Brożek JL, Akl EA, Jaeschke R, Lang DM, Bossuyt P, Glasziou P, Helfand M, Ueffing E, Alonso-Coello P, Meerpohl J, Phillips B, Horvath AR, Bousquet J, Guyatt GH, Schünemann HJ: Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies. Allergy, 2009; 64: 1109-1116. : http://dx.doi.org/10.1111/j.1398-9995.2009.02083.x
• Handke M, Geibel A, Kasper W, Olschewski M, Simon I: Diagnostischer Stellenwert verschiedener echo- und Dopplerechokardiographischer Methoden in der Quantifizierung von Mitralklappenstenosen. Zeitschrift für Kardiologie, 1996; 93: 1346-1353.
• Hauer, T, Lacour, M, Gastmeier, Schulgen G, Schumacher M, Rüden H, Daschner F: Nosokomiale Infektionen auf Intensivstationen. Eine bundesweite Prävalenzstudie (NIDEP). Anaesthesist, 1996; 45: 1184-1191.
• Hauer T, Huzly D, Gastmeier P, Schlingmann J, Schumacher M: Krankenhausinfektion in Gynäkologie und Geburtshilfe. Geburtshilfe und Frauenheilkunde, 1996; 56: 546-549.
• Heitzer T, Ylaherttuala S, Luoma J, Kurz S, Münzel T, Just H, Olschewski M, Drexler H: Cigarette smoking potentiates endothelial dysfunction of forearm resistance vessels in patients with hypercholesterolemia. Circulation, 1996; 93: 1346-1353.
• Ikenberg, H, Wiegering, I, Pfisterer J, Kiechle-Schwarz M, Schmitt B, Sauerbrei W, Pfleiderer A: Human Papillomavirus DNA in tumorfree regional lymph nodes - A potential prognostic marker in cervical carcinoma Cancer Journal from Scientific American, 1996; 2: 28-34.
• Kampf G, Gastmeier P, Wischnewski N, Schlingmann J, Schumacher M: Nosokomiale Infektionen in Deutschland - Erfassung und Prävention. NIDEP-Studie, Teil 1: Zur Prävalenz in der Chirurgie. Chirurg, 1996; 67: 637-642.
• Kampf G, Schumacher M, Daschner F, Rüden H: Postoperative Wundinfektionen in der Chirurgie - Prävalenz in Deutschland (NIDEP-Studie). Langenbecks Archiv für Chirurgie, Supplement II, 1996: 698-703.
• Krauss JK, Droste DW, Vach W, Regel JP, Orszagh M: Cerebrospinal fluid shunting in idiopathic normal-pressure hydrocephalus of the elderly: effect of periventricular and deep white matter lesions. Neurosurgery, 1996; 39: 292-299.
• Kropec A, Schulgen G, Just H, Geiger K, Schumacher M: Scoring system for nosocomial pneumonia in ICUs. Intensive Care Medicine, 1996; 22: 1155-1161.
• Kropec A, Schulgen G, Schumacher M, Just H, Geiger K: Entwicklung eines Risiko Scores für nosokomiale Sepsis bei Intensivpflegepatienten Intensivmedizin, 1996; 33: 126-132.
• Kunath F, Pittler M, Grobe H, Wullich B, Antes G: Die Arbeit der „Cochrane Collaboration“ in der Urologie. The work of the Cochrane Collaboration in urology. Urologe, 2011; 50: 328-332. : http://dx.doi.org/10.1007/s00120-010-2490-6
• Lausen B, Schumacher M: Evaluating the effect of optimized cutoff values in the assessment of prognostic factors. Computational Statistics & Data Analysis, 1996; 21: 307-326.
• Münzel T, Heitzer T, Kurz S, Harrison DG, Luhmann C, Pape L, Olschewski M, Just H: Dissociation of coronary vascular tolerance and neurohormonal adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease. Journal of the American College of Cardiology, 1996; 27: 297-303.
• Pfisterer J, Kommoss F, Sauerbrei W, Baranski B, Kiechle M: DNA flow cytometry in stage IB and II cervical carcinoma. International Journal of Gynecological Cancer, 1996; 6: 54-60.
• Pieske B, Sütterlin M, Schmidt-Schweda S, Miname K, Meyer M, Olschewski M, Holubarsch C, Just H, Hasenfuss G: Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy. Functional evidence for alterations in intracelluar Ca2+ handling. Journal of Clinical Investigation, 1996; 98: 764-776.
• Rüden H, Daschner F, Schumacher M: Gegendarstellung der Studienleiter der NIDEPStudie zum Kommentar: Ist die NIDEPStudie geeignet zur Häufigkeitsbeurteilung und Bewertung Hygiene und Medizin, 1996; 21: 445-448.
• Vandenbroucke JP, von Elm E, Altman DG, Gotzsche PC, Mulrow CD, Pocock SJ, Poole C, Schlesselman JJ, Egger M: Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration Epidemiology, 2007; 18 (6): 805-835.

• Beyersmann J, Allignol A, Schumacher M: Competing Risks and Multistate Models with R (Use R!)Springer Verlag, 2012 (Use R!). : http://www.springer.com/statistics/statistical+theory+and+methods/book/978-1-4614-2034-7
• Haes de JCM, Olschewski M, Fayers P, Visser MRM, Cull A: Measuring the quality of life of cancer patients with the Rotterdam Symptom Checklist (RSCL): A manual., hrsg. von Northern Centre for Healthcare Research, NCH series 9, Groningen, 1996.
• Perleth M, Antes G: Evidenzbasierte Medizin. Wissenschaft im Praxisalltag., München: Urban und Vogel, 3. Auflage, 2002.
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., Heidelberg: Springer Verlag, 1. Auflage, 2002.
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., Berlin Heidelberg: Springer Verlag, 2. Auflage, 2007.
• Schumacher M, Schulgen G: Methodik klinischer Studien. Methodische Grundlagen der Planung, Durchführung und Auswertung., New York - Heidelberg: Springer, 3. Auflage, 2008 (Statistik und ihre Anwendungen). : http://dx.doi.org/10.1007/978-3-540-85136-3

• Allgaier H-P, Galandi D, Becker G, Zuber I, Olschewski M, Blum HE: Natural course of hepatocellular carcinoma and non-surgical therapeutic options. In: Kamberts SWJ and Dogliotti L (Hrsg.): The expanding role of octeotride I: Advances in oncology BioScientifica, 2002; 157-179.
• Allgaier H-P, Olschewski M: HCC-Stadien und Prognose. In: Allgaier H-P (Hrsg.): Das hepatozelluläre Karzinom, 1. Auflage. Bremen: Uni-Med Verlag AG, 2002; 64-70.: http://www.uni-med.de
• Berger M, Antes G, Hecht H: Die Lehrbuchrelevanz von evidenzbasierter Medizin und der Cochrane Collaboration. In: Matthias Berger (Hrsg.): Psychische Erkrankungen. Klinik und Therapie., 2.. Auflage. München: Urban & Fischer, 2004; 4-16.
• Binder H, Gerds T, Schumacher M: Sirivival Risk Prediction Using High-Dimensional Molecular Data. In: Shigeyuki Matsui, Marc Buyse, Richard Simon (Hrsg.): Design and Analysis of Clinical Trials for Predicitive Medicine. New York: Chapman & Hall/CRC Biostatistics Series, 2015; 271-294.
• Blettner M, Sauerbrei W: Methodologische Aspekte bei der Untersuchung von Spontanremissionen von Tumoren. In: Heim, M.E. und Schwarz, R. (Hrsg.): Spontanremission in der Onkologie: theoretische Modelle und klinische Befunde; mit 20 Tabellen , 1998; 29-38.
• Feufel MA, Antes G, Steurer J, Gigerenzer G, Gray JAM, Mäkelä M, Mulley AG, Nelson DE, Schulkin J, Schünemann H, Wennberg JE, Wild C: What is needed for better health care: Better systems, better patients or both? In: G. Gigerenzer & J. A. M. Gray (Hrsg.): Better doctors, better patients, better decisions: Envisioning health care 2020. Cambridge: MA: MIT Press, 2011; 117-134 (Strüngmann Forum reports.).
• Gerlach A, Holländer N, Ihorst G, Olschewski M, Sauerbrei W, Schlingmann J, Schmoor C, Schulgen G, Schwarzer G, Schumacher M: Freiburg contributions to biometry and clinical epidemiology. In: Joachim Kunert und Götz Trenkler (Hrsg.): Mathematical Statistics with Applications in Biometry, 1. Auflage. Lohmar Köln: Josef Eul Verlag, 2001; 49-70.
• Graf E, Sauerbrei W, Schumacher M, Schmoor C: Berücksichtigung prognostischer Faktoren bei der Planung von Therapiestudien. In: Kunath, H., Lochmann, U., Straube, R., Jöckel, K.H., Köhler, C.O. (Hrsg.): Medizinische Informatik, Biometrie und Epidemiologie. , 1995; 475-480.
• Kommoss F, Pfisterer J, Thome M, Sauerbrei W, Pfleiderer A: Steroid Rezeptoren beim Ovarialkarzinom: Die immunhistochemische Bestimmung birgt neue Perspektiven. In: Meerpohl HG, Pfleiderer A, Profous CZ (Hrsg.): Das Ovarialkarzinom. Berlin - Heiderlberg: Springer, 1993; 119-129 (Bd 1 Tumorbiologie Screening, Staging.).
• Lausen B, Sauerbrei W, Schumacher M: Classification and regression trees used for the exploration of prognostic factors measured on different scales. In: Dirschedl, P., Ostermann, R. (Hrsg.): Computational Statistics. Physica-Verlag, Heidelberg, 1994; 483-496.
• Ohneberg K, Schumacher M: Sample Size Calculation for Clinical Trials. In: John P. Klein, Joseph G. Ibrahim, Thomas Scheike (Hrsg.): Handbook of Survival Analysis, 1. Auflage. Boca Raton: Chapman and Hall/CRC, 2013; 571-594 (Handbooks of Modern Statistical Methods).
• Olschewski M: Aspects of data management and statistical analysis. In: Zittoun R (Hrsg.): Quality of life of cancer patients: A review. Beaune: Laboratoire Roger Bellon, 1992; 103-111.
• Olschewski M: Quality of life and survival analysis. In: Armitage, P, Colton T (Hrsg.): Encyclopedia of Biostatistics John Wiley & Sons, 1998; 3613-3618.
• Rüden H, Daschner F, Schumacher, M: Nosokomiale Infektionen in Deutschland - Erfassung und Prävention (NIDEP-Studie), Teil 1 Abschlußbericht und Anhänge. In: Bundesministerium für Gesundheit (Hrsg.): NOMOS Verlagsgesellschaft Baden-Baden, 1995.
• Sauerbrei W, Blettner M: Issues of Reviews and Meta-Analyses of Observational Studies. In: Ralf Schulze, Heinz Holling, Dankmar Böhning (Hrsg.): Meta-Analysis. New Developments and Applications in Medical and Social Sciences. Göttingen: Hogrefe & Huber, 2003; 79-96.
• Sauerbrei W, Blettner M, Schumacher M: Basic statistical principles for the evaluation of risk factors. In: Madjar, H., Teubner, J., Hackelöer B-J (Hrsg.): Breast Ultrasound Update. Basel, Karger, 1994; 1-12.
• Sauerbrei W, Schumacher M: Klinische Studien als wichtiger Bestandtteil medizinischer Forschung: Aspekte der Planung, Durchführung und Auswertung In: Steiner W, Reck R, Dühmke E (Hrsg.): Funktonserhaltende Therapie des frühen Larynxkarzinoms Stuttgart New York: Thieme, 1990; 147-159.
• Sauerbrei W, Schumacher M: Boostrap and cross-validation to assess complexity of data-driven regression models In: Brause, RW and Hanisch, E (Hrsg.): Medical Data Analysis: first international symposium; proceedings Springer Berlin, 2000; 234-241.
• Sauerbrei W, Zaiss A, Lausen B, Schumacher M: Evaluierung prognostischer homogener Subpopulationen mit Hilfe der Methode der Klassifikationabäume. In: Guggenmoos-Holzmann I (Hrsg.): Quantitative Methoden in der Epidemiologie. Berlin - Heidelberg - New York: Springer, 1991; 229-234.
• Schauer A, Marx D, Lipp I, Meden H, Schumacher M, Sauerbrei W, Sauer R, Rauschecker H: Clinical and scientific aspects of HER 2/NEU erb B2-oncogenes: Biological relevance of c-erb B2-oncogene in malignant epithelial tumors. In: Löning J (Hrsg.): Clinical and scientific aspects of HER 2/NEU erb. International Symposium Hamburg 1991. Berlin: Springer, 1992.
• Schmoor C, Olschewski M, Schumacher M: Randomisierte und nicht-randomisierte Patienten in klinischen Therapiestudien: Erfahrungen mit dem CCS-Design. In: Kunath, H, Lochmann, U, Straube, R, Jöckel, KH, Köhler, CO (Hrsg.): Medizinische Informatik, Biometrie und Epidemiologie. , 1995; 444-449.
• Schmoor C, Schulgen G, Schumacher M: Studiendesign - Eine Einführung. In: Bassler D, Forster J, Antes G (Hrsg.): Evidenz-basierte Pädiatrie. Praxisnahes EBM-Handbuch für pädiatrische Diagnostik und Therapie Stuttgart, New York: Georg Thieme Verlag, 2001.
• Schröder T, Schumacher M: Graphische Methoden zur Analyse der Wirkstoffkumulation und Modifikation des Therapieschemas bei zyklischen Chemotherapien In: Medizinische Informatik, Biometrie und Epidemiologie GMDS , 1997; 378-381.
• Schumacher M: The Freiburg center of data analysis and model building (FDM): an interim report about an interdisciplinary cooperation. In: Klar, R, Opitz, O (Hrsg.): Classification and Knowledge Organization Springer-Verlag, 1997; 539-546.
• Schumacher M, Antes G, Olschewski M, Schmoor C: Überlebenszeitanalyse In: Rasch, D, Herrendörfer, G, Bock, J, Victor, N, Guiard, V (Hrsg.): Verfahrensbibliothek. Versuchsplanung und -auswertung. R. Oldenbourg Verlag, München Wien, 1998; 800-830.
• Schumacher M, Bastert G, Bojar H, Hübner K, Olschewski M, sauerbrei W, Schmoor C, for the German Breast Cancer Study Group (GBSG): A randomized clinical trial evaluating the duration of chemotherapy in patients with primary, node-positive breast cancer. In: Salmon SF (Hrsg.): Adjuvant therapy of cancer VII. Philadelphia: Lippincott, 1993; 193-203.
• Schumacher M, Holländer N, Schwarzer G, Binder H, Sauerbrei W: Prognostic Factor Studies. In: Crowley J, Hoering A (Hrsg.): Handbook of Statistics in Clinical Oncology, Third Edition. Chapman and Hall/CRC, 2012; 415-470.
• Schumacher M, Holländer N, Schwarzer G, Sauerbrei W: Prognostic Factor Studies. In: John Crowley (Hrsg.): Handbook of Statistics in Clinical Oncology New York - Basel: Marcel Dekker, Inc., 2001; 321-378.
• Schumacher M, Holländer N, Schwarzer G, Sauerbrei W: Prognostic Factor Studies. In: John Crowley and Donna Pauler Ankerst (Hrsg.): Handbook of Statistics in Clinical Oncology., 2. Auflage. Boca Raton, FL: Chapman & Hall /CRC, 2006; 289-333.
• Schumacher M, Olschewski M: Evaluierung von Lebensqualität in klinischen Studien. In: Meerpohl HG, Pfleiderer A, Profous CZ (Hrsg.): Das Rezidiv in der Gynäkologischen Onkologie. Berlin - Heiderlberg - New York: Springer-Verlag, 1990; 267-275.
• Schumacher M, Olschewski M: Auswertung randomisierter und nicht-randomisierter Patienten in klinischen Studien. In: Giani G, Repges R (Hrsg.): Biometrie und Informatik - neue Wege zur Erkenntnisgewinnung. Heidelberg: Springer-Verlag, 1990; 61-71.
• Schumacher M, Sauerbrei W: Statistische Aspekte der Planung, Durchführung und (Meta-) Analyse. In: Meerpohl HG, Pfleiderer A, Profous CZ (Hrsg.): Das Ovarialkarzinom. Bd. 2 Therapie. Berlin - Heidelberg: Springer-Verlag, 1993; 71-85.
• Schumacher M, Schmoor C: Statistical Analysis af the Ames assay. In: Hothorn L (Hrsg.): Statistical methods in toxicology. Berlin - Heidelberg - New York: Springer, 1991; 5-19.
• Schwarzer G, Antes G, Schumacher M: Statistical tests for the detection of bias in meta-analysis. In: Ralf Schulze, Heinz Holling, Dankmar Böhning (Hrsg.): Meta-Analysis. New Developments and Applications in Medical and Social Sciences. Göttingen: Hogrefe & Huber, 2003; 72-78.
• Schwarzer G, Vach W, Schumacher M: On the misuses of artificial neural networks for prognostic and diagnostic classification in oncology. In: Haux R, Kulikowski C (Hrsg.): Yearbook of Medical Informatics 2002 Stuttgart: Schattauer Verlagsgesellschaft mbH, 2002; 501-521.
• Timmer A, Gross M: Evidenz in der Gynäkologie und Geburtshilfe. In: Wacker J, Sillem M, Bastert G, Beckmann MW (Hrsg.): Therapiehandbuch Gynäkologie und Geburtshilfe. Heidelberg: Springer, 2007; 3-18.
• Vach W, Blettner M: Missing data in epidemiological studies. In: Armitage, P, Colton T (Hrsg.): Encyclopedia of Biostatistics John Wiley & Sons, 1998; 2641-2654.
• Vach W, Schumacher M: Logistic regression with incompletely observed covariates. In: Schach S, Trenkler G (Hrsg.): Data analysis and statistical inference - Festschrift in Honour of Friedhelm Eicker. Bergisch-Gladbach: Eul-Verlag, 1992; 219-138.

• Meerpohl HG, Sauerbrei W, Schumacher M, Pfleiderer A (Hrsg.): Welche Parameter beeinflussen die Größe des postoperativen Tumorrestes beim fortgeschrittenen Ovarialkarzinom?, Berlin: Springer-Verlag, 1990 (Berichte Gynäkologie Geburtshilfe 127).

• Merger M, Andus T, Schlottmann K, Timmer A, Scholmerich J, Messmann H, Marienhagen J, Rummle P, Krolak C: A rare case of hypalbuminaemic oedema. Gut, 2005; 54: 320-335.

• Antes G, Clarke M: Knowledge as a key resource for health challenges. Lancet, 2012; 379: 195-196. : http://dx.doi.org/10.1016/S0140-6736(12)60084-1
• Beyersmann J, Gerds T, Schumacher M: Letters to the Editor. Snapinn, S.M., Jiang, Q., and Iglewicz, B. (2005), "Illustrating the impact of a time-varying covariate with an extended Kaplan-Meier estimator", The American Statistician, 59, 301-307: Comment by Beyersmann, Gerds, and Schumacher and Response. Am Stat, 2006; 60: 295-297.
• Beyersmann J, Meerpohl J, Dettenkofer M, Wolkewitz M, Schumacher M: Risk factors disrupting mucosal integrity and subsequent vancomycin-resistant enterococcus infection. Pediatr Blood Cancer, 2010; 54: 184. : http://dx.doi.org/10.1002/pbc.22268
• Beyersmann J, Schumacher M: Misspecified regression model for the subdistribution hazard of a competing risk Latouche A, Boisson V, Chevret S and Porcher R. Stat Med, 2007; 26: 1649-1651.
• Binder N, Schumacher M, Joly P: Re: “Incidence of Dementia Among Participants and Nonparticipants in a Longitudinal Study of Cognitive Aging” Am J Epidemiol, 2015; 181: 290-292. : http://dx.doi.org/10.1093/aje/kwu475
• Clarke M, Antes G, Moher D: 4,000 high quality reviews and counting: a vast wealth of knowledge in The cochrane Library. Cochrane News, 2009; 47: 1-2.
• Graf E, Schumacher M: Comments on 'The performance of different propensity score methods for estimating marginal odds ratios' by Peter C. Austin, Statistics in Medicine 2007; 26(16):3078-3094. Stat Med, 2008; 27: 3915-3917. : http://dx.doi.org/10.1002/sim.3271
• Höfling H, Eckert C, Schumacher M: "Classification of therapy resistance based on longitudinal biomarker profiles" by M. Kohlmann, L. Held and V. P. Grunert Biometrical Journal (2009) 51(4):610–626 Article: http://dx.doi.org/10.1002/bimj.200800157. Authors' reply: http://dx.doi.org/10.1002/bimj.201000119 Biometrical J, 2010; 52: 562-566. : http://dx.doi.org/10.1002/bimj.201000054
• Ihorst G, Waldschmidt J, Schumacher M, Wäsch R, Engelhardt M: Analysis of survival by tumor response: have we learnt any better? Ann Hematol, 2015; 94: 1615-1616. : http://dx.doi.org/10.1007/s00277-015-2426-8
• Jena S, Dreier G, Antes G, Schumacher M: Clinical trials. More transparency in EU testing? European Biotechnology News, 2010; 9 (5-6): 28-30.
• Lambert M-L, Suetens C, Frank U, Wolkewitz M: Clinical impact of antimicrobial resistance: design matters – Authors' reply. Lancet Infect Dis, 2011; 11: 344-345. : http://dx.doi.org/10.1016/S1473-3099(11)70108-6
• McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM: Re: Reporting recommendations for tumor marker prognostic studies (REMARK), Response of Authors. J Natl Cancer I, 2005; 97: 1855-1856.
• Rücker G, Graf E, Schumacher M: Letter to the editor concerning Shadish WR, Clark MH, Steiner PM: Can Nonrandomized Experiments Yield Accurate Answers? A Randomized Experiment Comparing Random and Nonrandom Assignments. Journal of the American Statistical Association. December 1, 2008, 103(484): 1334-1344. doi:10.1198/016214508000000733. [Website: http://pubs.amstat.org/doi/abs/10.1198/016214508000000733]. J Am Stat Assoc, 2010 (online): 1-6. : http://pubs.amstat.org/doi/suppl/10.1198/016214508000000733/suppl_file/Letter.pdf
• Rücker G, Schumacher M: Letter to the editor. Biostatistics, 2009; 10: 806-807. : http://dx.doi.org/10.1093/biostatistics/kxp021
• Rücker G, Schumacher M: Procalcitonin as a diagnostic marker for sepsis. Lancet Infect Dis, 2013; 13: 1012-1013. : http://dx.doi.org/10.1016/S1473-3099(13)70303-7
• Rücker G, Schwarzer G, Carpenter J, Schumacher M: Comments on ‘Empirical vs natural weighting in random effects meta-analysis’ by JJ Shuster, Statistics in Medicine 2009; 26, Published online, DOI: 10.1002/sim.3607. Stat Med, 2010; 29: 2963-2966. : http://dx.doi.org/10.1002/sim.3957
• Rücker G, Schwarzer G, Schumacher M, Carpenter J: Are large trials less reliable than small trials? J Clin Epidemiol, 2009; 62: 886-889. : http://dx.doi.org/10.1016/j.jclinepi.2009.03.007
• Sauerbrei W, Royston P, Schumacher M: Austin, P.C., and Tu, J.V. (2004), "Bootstrap Methods for developing predictive models", The American Statistician,58, 131-137: Comment by Sauerbrei, Royston, and Schumacher to reply. Am Stat, 2005; 59: 116-118.
• Sauerbrei W, Royston P, Schumacher M: Comments on ‘Performance of using multiple stepwise algorithms for variable selection’ by Ryan E. Wiegand, Statistics in Medicine 2010; 29:1647–1659. Stat Med, 2011; 30: 892-894. : http://dx.doi.org/10.1002/sim.4083
• Schmucker C, Antes G, Lelgemann M: A systematic review on the effect of bevacizumab in exudative age-related macular degeneration. Graef Arch Clin Exp, 2010; 248 (3): 451-452. : http://dx.doi.org/10.1007/s00417-009-1249-5
• Schneck J, Fagot J-P, Sekula P, Sassolas B, Roujeau JC, Mockenhaupt M: Reply: The EuroSCAR study: Cannot agree with the conclusions. J Am Acad Dermatol, 2008; 59: 899-900. : http://dx.doi.org/10.1016/j.jaad.2008.07.005
• Schumacher M, Rücker G, Schwarzer G: Meta-Analysis and the Surgeon General's Report on Smoking and Health. New Engl J Med, 2014; 370: 186-188. : http://dx.doi.org/10.1056/NEJMc1315315
• Winterfeld U, Allignol A, Panchaud A, Rothuizen LE, Merlob P, Cuppers-Maarschalkerweerd B, Vial T, Stephens S, Clementi M, De Santis M, Pistelli A, Berlin M, Eleftheriou G, Maňáková E, Buclin T: Authors' response to: Statins in pregnancy: safety and perspectives of therapeutic applications. Bjog-int J Obstet Gy, 2013; 120: 1440. : http://dx.doi.org/10.1111/1471-0528.12280
• Witkowski S, Yajima N-D, Wolkewitz M, Strub JR: Responding to manuscript CLOI-D-10-00562: Reliability of shade selection using an intraoral spectrophotometer. Clin Oral Invest, 2013; 17: 1027-1028. : http://dx.doi.org/10.1007/s00784-013-0931-5
• Wolkewitz M: Avoidable statistical pitfalls in analyzing length of stay in intensive care units or hospitals. Crit Care, 2014; 18: 408. : http://dx.doi.org/10.1186/cc13735
• Wolkewitz M: Estimating the Risk of Ventilator-associated Pneumonia as a Function of Time. American Journal of Respiratory and Critical Care Medicine, 2015; 192: 640-641. : http://dx.doi.org/10.1164/rccm.201502-0282LE
• Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Regression modelling in hospital epidemiology: a statistical note. Crit Care, 2008; 12: 427. : http://dx.doi.org/10.1186/cc6991
• Wolkewitz M, Beyersmann J, Schumacher M: Consequences of immortal time bias on extra length of hospital stay due to nosocomial infections. Rapid Response to: Lévesque LE, Hanley JA, Kezouh A, Suissa S: Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ 2010; 340: b5087 [http://www.bmj.com/content/340/bmj.b5087.long/reply#bmj_el_233676]. Brit Med J, 2010 (online): 30 Mar. : http://www.bmj.com/content/340/bmj.b5087.long/reply#bmj_el_233676
• Wolkewitz M, Di Termini S, Cooper B, Meerpohl J, Schumacher M: Paediatric hospital-acquired bacteraemia in developing countries. Lancet, 2012; 379: 1484. : http://dx.doi.org/10.1016/S0140-6736(12)60624-2
• Wolkewitz M, Harbarth S, Beyersmann J: Daily chlorhexidine bathing and hospital-acquired infection. New Engl J Med, 2013; 368: 2330. : http://dx.doi.org/10.1056/NEJMc1304820
• Wolkewitz M, Schumacher M: Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality. The Lancet Respiratory Medicine, 2014; 2 (online): e8-e9. : http://dx.doi.org/10.1016/S2213-2600(14)70115-8
• Wolkewitz M, Sommer H: Evaluating mortality in an intensive care unit requires extended survival models. Crit Care, 2014; 18: 415. : http://dx.doi.org/10.1186/cc13757
• Wolkewitz M, Tacconelli E, Schumacher M: Aggressive versus conservative initiation of antibiotics. Lancet Infect Dis, 2013; 13: 387-388. : http://dx.doi.org/10.1016/S1473-3099(13)70063-X

• Bluemle A, Meerpohl J, Ruecker G, Antes G, Schumacher M, von Elm E: Reporting of eligibility criteria of randomised trials: empirical study comparing trial protocols to subsequent articles. J Epidemiol Commun H, 2011; 65: A216-A216. : http://dx.doi.org/10.1136/jech.2011.142976h.28
• Blümle A, Kasenda B, Saccilotto R, Briel M, von Elm E: P2B219: Epidemiology and publication history of randomized controlled trials that were discontinued. 2011 (19. Cochrane Colloquium, Madrid). (download: http://2011.colloquium.cochrane.org/scientific-programme/posters-session-2)
• Cameron M, Chrubasik S, Parsons T, Gagnier JJ, Blümle A, Little C: Herbal therapy for treating osteoarthritis: update of a cochrane review. Ann Rheum Dis, 2007; 66 Suppl. 2: 494.
• Cameron M, Gagnier JJ, Chrubasik S, Blümle A, Parsons T, Little C: Herbal therapy for treating rheumatoid arthritis: update of a cochrane review. Ann Rheum Dis, 2007; 66 Suppl. 2: 602.
• Holländer N, Schumacher M: Zum Einfluss der Modellbildung auf die Schätzung von Konfidenzintervallen für prognostische Faktoren am Beispiel des Cutpointmodells. Informatik, Biometrie und Epidemiologie in Medizin und Biologie, 2001; 32 (2-3): 177 (46. Jahrestagung der GMDS), Urban & Fischer (Hrsg). : http://www.urbanfischer.de/journals/ibe
• Motschall E, Rücker G, Antes G, Schumacher M: The number needed to read: are capture-recapture techniques feasible in searching literature of systematic reviews? Cochrane Db Syst Rev, 2009; 3 (online): CD000001. : http://onlinelibrary.wiley.com/o/cochrane/clcmr/articles/CMR-14037/frame.html
• Muth C, Aksamit N, von Büdingen F, Motschall E, van Den Akker M, Blom JW, Beyer M, Kühlein T, Lang B: Patientenpräferenzen bei Multimorbidität und Multimedikation – Pilotierung einer Evidence Map. GMS German Medical Science, 2015 (online): Doc15 (49. Kongress für Allgemeinmedizin und Familienmedizin, 17. - 19.09.2015, Bozen, Italien. Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM)). : http://dx.doi.org/10.3205/15degam118
• Porter J, Walter P, Neumayr L, Evans P, Weyhmiller M, Harmatz P, Wood J, Miller J, Weiss G, Yuan Q, Wang Z, Grosse R, Schoennagel B, Meerpohl J, Fischer R, Nielsen P, Seifert M, Vichinsky E: BIO-MARKERS OF IRON TRAFFICKING AND DISTRIBUTION IN TRANSFUSIONAL OVERLOAD: INSIGHTS FROM COMPARING DIOND BLACKFAN ANEMIA WITH SICKLE CELL DISEASE AND THALASSEMIA (MCSIO PILOT STUDY) Am J Hematol, 2013; 88 (5): E46-E47. : http://dx.doi.org/10.1002/ajh.23453
• Simmonds L, Clarke M, et al.: Are you listening? Podcasts from The Cochrane Library; a review. Supplement, 2010: 115 (18th Cochrane Colloquium and 10th Campbell Colloquium. Keystone, Colorado, USA), John Wiley & Sons, Ltd. (Hrsg).
• Wolkewitz M, Schmacher M: Analysing outbreak data in a heterogeneous population with migration. IFAC Proceedings, 2009; 7 (1) (online): 309-312 (7th IFAC Symposium on Modelling and Control in Biomedical Systems). : http://dx.doi.org/10.3182/20090812-3-DK-2006.00054

• Bohlius J, Reiser M, Schwarzer G, Engert A: Granulopoiesis-stimulating factors in the prevention for adverse effects in the therapeutic treatment of malignant lymphoma (Cochrane Review). Update Software, Oxford. In The Cochrane Library, 2002; 4.
• Henderson R, Schumacher M: Clinical epidemiology and individualized medicine. Biometrical J, 2011; 53: 167-169. : http://dx.doi.org/10.1002/bimj.201000257
• Kasenda B, Sauerbrei W, Royston P, Briel M: Investigation of continuous effect modifiers of higheror lower PEEP in mechanically ventilated patients with acute lung injury or ARDS – ICEMstudy. 2012. : http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012003129
• Klemperer D, Lang B, Koch K, Bastian H, Brunsmann F, Burkhardt M, Dierks M-L, Ehrmann U, Günther J, Härter M, Mühlhauser I, Sänger S, Simon D, Steckelberg A: Die ‚Gute Praxis Gesundheitsinformation’. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen, 2010; 104: 66-68. : http://dx.doi.org/10.1016/j.zefq.2009.12.018
• Langensiepen S, Bohlius J, Seidenfeld J, Piper M, Bennett C, Schwarzer G, Engert A: Erythropoietin for patients with malignant disease (Protocol for a Cochrane Review). Cochrane Library, 2003; 2: ---. : http://Update Software, Oxford
• Schumacher M: Probability estimation and machine learning—Editorial. Biometrical J, 2014; 56: 531-533. : http://dx.doi.org/10.1002/bimj.201400075

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten

• Holländer N: Estimating the functional form of the effect of a continuous covariate on survival time. (Erstgutachter/in Prof. Dr. M. Schumacher, Zweitgutachter/in Prof. Dr. W. Urfer), 2002.
• Schwarzer G: Statistical tests for bias in meta-analysis with binary outcomes. (Erstgutachter/in Prof. Dr. Joachim Hartung, Zweitgutachter/in Prof. Dr. Wolfgang Urfer), 2004.

• Meier-Hirmer C: Multi-State Models for the Long-Term Prognosis of Breast-Cancer (Erstgutachter/in Prof. Dr. M. Schumacher, Zweitgutachter/in Prof. Dr. H. R. Lerche), 2002.