Scientific publications
Journal Articles:
- Abouassi T, Hannig C, Mahncke K, Karygianni L, Wolkewitz M, Hellwig E, Al-Ahmad1 A: Does human saliva decrease the antimicrobial activity of chlorhexidine against oral bacteria? BMC Research Notes, 2014; 7 (online): 711. : http://dx.doi.org/10.1186/1756-0500-7-711
- Abouassi T, Wolkewitz M, Hahn P: Effect of carbamide peroxide and hydrogen peroxide on enamel surface: an in vitro study. Clin Oral Invest, 2011; 15: 673-680. : http://dx.doi.org/10.1007/s00784-010-0439-1
- Al-Ahmad A, Roth D, Wolkewitz M, Wiedmann-Al-Ahmad M, Follo M, Ratka-Krüger P, Deimling D, Hellwig E, Hannig C: Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm. Clin Oral Invest, 2010; 14: 391-396. : http://dx.doi.org/10.1007/s00784-009-0318-9
- Al-Ahmad A, Wiedmann-Al-Ahmad M, Fackler A, Follo M, Hellwig E, Bächle M, Hannig C, Han J-S, Wolkewitz M, Kohal R: In vivo study of the initial bacterial adhesion on different implant materials. Arch Oral Biol, 2013; 58: 1139-1147. : http://dx.doi.org/10.1016/j.archoralbio.2013.04.011
- Al-Ahmad A, Wiedmann-Al-Ahmad M, Faust J, Bächle M, Follo M, Wolkewitz M, Hannig C, Hellwig E, Carvalho C, Kohal R: Biofilm formation and composition on different implant materials in vivo. J Biomed Mater Res B, 2010; 95: 101-109. : http://dx.doi.org/10.1002/jbm.b.31688
- Att W, Yajima N-D, Wolkewitz M, Witkowski S, Strub JR: Influence of preparation and wall thickness on the resistance to fracture of zirconia implant abutments. Clin Implant Dent R, 2012; 14 Suppl. 1: e196-e203. : http://dx.doi.org/10.1111/j.1708-8208.2011.00428.x
- Auschill TM, Koch CA, Wolkewitz M, Hellwig E, Arweiler NB: Occurrence and causing stimuli of postoperative sensitivity in composite restorations. Oper Dent, 2009; 34: 3-10. : http://dx.doi.org/10.2341/08-7
- Barnett AG, Beyersmann J, Allignol A, Rosenthal VD, Graves N, Wolkewitz M: The time-dependent bias and its effect on extra length of stay due to nosocomial infection. Value Health, 2011; 14: 381-386. : http://dx.doi.org/10.1016/j.jval.2010.09.008
- Bateli M, Kern M, Wolkewitz M, Strub JR, Att W: A retrospective evaluation of teeth restored with zirconia ceramic posts: 10-year results. Clin Oral Invest, 2014; 18: 1181-1187. : http://dx.doi.org/10.1007/s00784-013-1065-5
- Beyersmann J, Gastmeier P, Wolkewitz M, Schumacher M: An easy mathematical proof showed that time-dependent bias inevitably leads to biased effect estimation. J Clin Epidemiol, 2008; 61: 1216-1221. : http://dx.doi.org/10.1016/j.jclinepi.2008.02.008
- Beyersmann J, Wolkewitz M, Allignol A, Grambauer N, Schumacher M: Application of multistate models in hospital epidemiology: Advances and challenges. Biometrical J, 2011; 53: 332-350. : http://dx.doi.org/10.1002/bimj.201000146
- Beyersmann J, Wolkewitz M, Schumacher M: The impact of time-dependent bias in proportional hazards modelling. Stat Med, 2008; 27: 6439-6454. : http://dx.doi.org/10.1002/sim.3437
- De Angelis G, Allignol A, Murthy A, Wolkewitz M, Beyersmann J, Safran E, Schrenzel J, Pittet D, Harbarth S: Multistate modelling to estimate the excess length of stay associated with meticillin-resistant Staphylococcus aureus colonisation and infection in surgical patients. J Hosp Infect, 2011; 78: 86-91. : http://dx.doi.org/10.1016/j.jhin.2011.02.003
- de Kraker MEA, Wolkewitz M, Davey PG, Grundmann H, on behalf of the BURDEN Study Group: Clinical impact of antimicrobial resistance in European hospitals: Excess mortality and length of hospital stay related to Methicillin-resistant staphylococcus aureus bloodstream infections. Antimicrob Agents Ch, 2011; 55: 1598-1605. : http://dx.doi.org/10.1128/AAC.01157-10
- Encke BS, Heydecke G, Wolkewitz M, Strub JR: Results of a prospective randomized controlled trial of posterior ZrSiO4-ceramic crowns. J Oral Rehabil, 2009; 36: 226-235. : http://dx.doi.org/10.1111/j.1365-2842.2008.01918.x
- Graves N, Barnett AG, Halton K, Crnich C, Cooper B, Beyersmann J, Wolkewitz M, Samore M, Harbarth S: The Importance of Good Data, Analysis, and Interpretation for Showing the Economics of Reducing Healthcare-Associated Infection. Infection Control and Hospital Epidemiology, 2011; 32: 927-928. : http://dx.doi.org/10.1086/661600 (download: http://www.jstor.org/stable/10.1086/661600)
- Guess PC, Kulis A, Witkowski S, Wolkewitz M, Zhang Y, Strub JR: Shear bond strengths between different zirconia cores and veneering ceramics and their susceptibility to thermocycling. Dent Mater, 2008; 24: 1556-1567. : http://dx.doi.org/10.1016/j.dental.2008.03.028
- Guess PC, Schultheis S, Wolkewitz M, Zhang Y, Strub JR: Influence of preparation design and ceramic thicknesses on fracture resistance and failure modes of premolar partial coverage restorations. J Prosthet Dent, 2013; 110: 264-273. : http://dx.doi.org/10.1016/S0022-3913(13)60374-1
- Guess PC, Strub JR, Steinhart N, Wolkewitz M, Stappert CFJ: All-ceramic partial coverage restorations—Midterm results of a 5-year prospective clinical splitmouth study. J Dent, 2009; 37: 627-637. : http://dx.doi.org/10.1016/j.jdent.2009.04.006
- Guess PC, Vagkopoulou T, Zhang Y, Wolkewitz M, Strub JR: Marginal and internal fit of heat pressed versus CAD/CAM fabricated all-ceramic onlays after exposure to thermo-mechanical fatigue. J Dent, 2014; 42: 199-209. : http://dx.doi.org/10.1016/j.jdent.2013.10.002
- Hahn P, Schondelmaier N, Wolkewitz M, Altenburger MJ, Polydorou O: Efficacy of tooth bleaching with and without light activation and its effect on the pulp temperature: an in vitro study. Odontology, 2013; 101: 67-74. : http://dx.doi.org/10.1007/s10266-012-0063-4
- Hannig C, Kupilas FJ, Wolkewitz M, Attin T: Die Validität von Entscheidungskriterien bei der Füllungserneuerung. Schweizerische Monatsschrift für Zahnmedizin (SMfZ), 2009; 119: 328-338.
- Heydecke G, Akkad AS, Wolkewitz M, Vogeler M, Türp JC, Strub JR: Patient ratings of chewing ability from a randomised crossover trial: lingualised vs. first premolar/canine-guided occlusion for complete dentures. Gerodontology, 2007; 24: 77-86.
- Heydecke G, Vogeler M, Wolkewitz M, Türp JC, Strub JR: Simplified versus comprehensive fabrication of complete dentures: Patient ratings of denture satisfaction from a randomized crossover trial. Quintessence Int, 2008; 39: 107-116.
- Horvath SD, Altenburger MJ, Naumann M, Wolkewitz M, Schirrmeister JF: Cleanliness of dentinal tubules following gutta-percha removal with and without solvents: a scanning electron microscopic study. Int Endod J, 2009; 42: 1032-1038. : http://dx.doi.org/10.1111/j.1365-2591.2009.01616.x
- Kaier K, Lambert ML, Frank UK, Vach W, Wolkewitz M, Tacconelli E, Rello J, Theuretzbacher U, Martin M: Impact of availability of guidelines and active surveillance in reducing the incidence of ventilator-associated pneumonia in Europe and worldwide. Bmc Infect Dis, 2014; 14 (online): 199. : http://dx.doi.org/10.1186/1471-2334-14-199
- Kaier K, Wilson C, Chalkley M, Davey PG, Suetens C, Grundmann H, de Kraker M, Schumacher M, Wolkewitz M, Frank U: Health and economic impacts of antibiotic resistance in European hospitals – Outlook on the BURDEN project. Infection, 2008; 36: 492-494. : http://dx.doi.org/10.1007/s15010-008-7453-0
- Kaier K, Wilson C, Hulscher M, Wollersheim H, Huis A, Borg M, Scicluna E, Lambert M-L, Palomar M, Tacconelli E, De Angelis G, Schumacher M, Wolkewitz M, Kleissle E-M, Frank U: Implementing strategic bundles for infection prevention and management. Infection, 2012; 40: 225-228. : http://dx.doi.org/10.1007/s15010-011-0186-5
- Karygianni L, Wiedmann-Al-Ahmad M, Finkenzeller G, Sauerbier S, Wolkewitz M, Hellwig E, Al-Ahmad A: Enterococcus faecalis affects the proliferation and differentiation of ovine osteoblast-like cells. Clin Oral Invest, 2012; 16: 879-887. : http://dx.doi.org/10.1007/s00784-011-0563-6
- Karygiann L, Follo M, Hellwig E, Burghardt D, Wolkewitz M, Anderson A, Al-AhmaD A: Microscope-based imaging platform for large-scale analysis of oral biofilms. Appl Environ Microb, 2012; 78: 8703-8711. : http://dx.doi.org/10.1128/AEM.02416-12
- Kohal RJ, Wolkewitz M, Hinze M, Han J-S, Bächle M, Butz F: Biomechanical and histological behavior of zirconia implants: an experiment in the rat. Clin Oral Implan Res, 2009; 20: 333-339. : http://dx.doi.org/10.1111/j.1600-0501.2008.01656.x
- Kohal RJ, Wolkewitz M, Tsakona A: The effects of cyclic loading and preparation on the fracture strength of zirconium-dioxide implants: an in vitro investigation. Clin Oral Implan Res, 2011; 22: 808-814. (download: http://dx.doi.org/10.1111/j.1600-0501.2010.02067.x)
- Kohal R-J, Wolkewitz M, Mueller C: Alumina-reinforced zirconia implants: survival rate and fracture strength in a masticatory simulation trial. Clin Oral Implan Res, 2010; 21: 1345-1352. : http://dx.doi.org/10.1111/j.1600-0501.2010.01954.x
- Kraker de MEA, Wolkewitz M, Davey PG, KollerW, Berger J, Nagler J, Icket C, Kalenic S, Horvatic J, Seifert H, Kaasch A, Paniara O, Argyropoulou A, Bompola M, Smyth E, Skally M, Raglio A, Dumpis U, Melbarde Kelmere A, Borg M, Xuereb D, Ghita MC, Noble M, Kolman J, Grabljevec S, Turner D, Lansbury L, Grundmann H: Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporins. J Antimicrob Chemoth, 2011; 66: 398-407. : http://dx.doi.org/10.1093/jac/dkq412
- Kruse E-B, Conrad A, Wenzler-Röttele S, Jonas D, Dettenkofer M, Wolkewitz M, Meyer E, Serr A: Extended-spectrum beta-lactamase-producing Enterobacter cloacae in mobile dialysis units in the medical and surgical departments of a university hospital: a case-control study. J Hosp Infect, 2010; 75: 33-36. : http://dx.doi.org/10.1016/j.jhin.2010.01.015
- Lambert M-L, Suetens C, Savey A, Palomar M, Hiesmayr M, Morales I, Agodi A, Frank U, Mertens K, Schumacher M, Wolkewitz M: Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect Dis, 2011; 11: 30-38. : http://dx.doi.org/10.1016/S1473-3099(10)70258-9
- Nikolaus F, Wolkewitz M, Hahn P: Bond strength of composite resin to glass ceramic after saliva contamination. Clin Oral Invest, 2013; 17: 751-755. : http://dx.doi.org/10.1007/s00784-012-0768-3
- Nova V, Karygianni L, Altenburger MJ, Wolkewitz M, Kielbassa AM, Wrbas K-T: Pull-out bond strength of a fibre-reinforced composite post system luted with self-adhesive resin cements. J Dent, 2013; 41: 1020-1026. : http://dx.doi.org/10.1016/j.jdent.2013.08.011
- Polydorou O, Huberty C, Wolkewitz M, Bolek R, Hellwig E, Kümmerer K: The effect of storage medium on the elution of monomers from composite materials. J Biomed Mater Res B, 2012; 100: 68-74. : http://dx.doi.org/10.1002/jbm.b.31923
- Polydorou O, König A, Altenburger MJ, Wolkewitz M, Hellwig E, Kümmerer K: Release of monomers from four different composite materials after halogen and LED curing. Am J Dent, 2011; 24: 315-321.
- Polydorou O, Rogatti P, Bolek R, Wolkewitz M, Kümmerer K, Hellwig E: Elution of monomers from three different bonding systems and their antibacterial effect. Odontology, 2013; 101: 170-176. : http://dx.doi.org/10.1007/s10266-012-0071-4
- Polydorou O, Wirsching M, Wolkewitz M, Hahn P: Three-Month Evaluation of Vital Tooth Bleaching Using Light Units—A Randomized Clinical Study. Oper Dent, 2013; 38 (1): 21-32. : http://dx.doi.org/10.2341/12-041-C
- Proksch S, Steinberg T, Keller C, Wolkewitz M, Wiedmann-Al-Ahmad M, Finkenzeller G, Hannig C, Hellwig E, Al-Ahmad A: Human saliva exposure modulates bone cell performance in vitro. Clin Oral Invest, 2012; 16: 69-77. : http://dx.doi.org/10.1007/s00784-010-0506-7
- Sauerbier S, Gutwald R, Wiedmann-Al-Ahmad M, Wolkewitz M, Haberstroh J, Obermeyer J, Kuenz A, Betz H, Wolter F, Duttenhöfer F, Schmelzeisen R, Nagursky H, Proksch S, Al-Ahmad A: Effect of gabapentin-lactam and gamma-aminobutyric acid/lactam analogs on proliferation and phenotype of ovine mesenchymal stem cells. Int J Oral Max Impl, 2013; 28 (online): e230-e238. : http://dx.doi.org/10.11607/jomi.te02
- Schumacher M, Allignol A, Beyersmann J, Binder N, Wolkewitz M: Hospital-acquired infections—appropriate statistical treatment is urgently needed! Int J Epidemiol, 2013; 42: 1502-1508. : http://dx.doi.org/10.1093/ije/dyt111
- Schumacher M, Wangler M, Wolkewitz M, Beyersmann J: Attributable mortality due to nosocomial infections - A simple and useful application of multistate models. Method Inform Med, 2007; 46: 595-600.
- Tchorz Jp, Doll R, Wolkewitz M, Hellwig E, Hannig C: Microhardness of composite materials with different organic phases in deep class II cavities: An in vitro study. Oper Dent, 2011; 36: 502-511. : http://dx.doi.org/10.2341/10-325-L
- Witkowski S, Yajima N-D, Wolkewitz M, Strub JR: Reliability of shade selection using an intraoral spectrophotometer. Clin Oral Invest, 2012; 16: 945-949. : http://dx.doi.org/10.1007/s00784-011-0590-3
- Wolkewitz M, Allignol A, Graves N, Barnett AG: Is 27 really a dangerous age for famous musicians? Retrospective cohort study. Brit Med J, 2011; 343 (online): d7799. : http://dx.doi.org/10.1136/bmj.d7799
- Wolkewitz M, Allignol A, Harbarth S, de Angelis G, Schumacher M, Beyersmann J: Time-dependent study entries and exposures in cohort studies can easily be sources of different and avoidable types of bias. J Clin Epidemiol, 2012; 65: 1171-1180. : http://dx.doi.org/10.1016/j.jclinepi.2012.04.008
- Wolkewitz M, Allignol A, Schumacher M, Beyersmann J: Two pitfalls in survival analyses of time-dependent exposure: a case study in a cohort of Oscar Nominees. Am Stat, 2010; 64: 205-211. : http://dx.doi.org/10.1198/tast.2010.08259
- Wolkewitz M, Barnett AG, Palomar Martinez M, Frank U, Schumacher M, IMPLEMENT Study Group: Interventions to control nosocomial infections: study designs and statistical issues. J Hosp Infect, 2014; 86: 77-82. : http://dx.doi.org/10.1016/j.jhin.2013.09.015
- Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Modeling the effect of time-dependent exposure on intensive care unit mortality. Intens Care Med, 2009; 35: 826-832. : http://dx.doi.org/10.1007/s00134-009-1423-6
- Wolkewitz M, Beyersmann J, Gastmeier P, Schumacher M: Efficient risk set sampling when a time-dependent exposure is present.
Matching for time to exposure versus exposure density sampling. Method Inform Med, 2009; 48: 438-443. : http://dx.doi.org/10.3414/ME9241
- Wolkewitz M, Beyersmann J, Schumacher M: A note on statistical association and causality derived from epidemiological ICU data. Intens Care Med, 2010; 36: 549. : http://dx.doi.org/10.1007/s00134-009-1721-z
- Wolkewitz M, Bruckner T, Schumacher M: Accurate variance estimation for prevalence ratios. Method Inform Med, 2007; 46: 567-571.
- Wolkewitz M, Cooper B, Barnett AG, Binder N, Schumacher M: Treatment of hospital-acquired pneumonia. Lancet Infect Dis, 2011; 11: 729. : http://dx.doi.org/10.1016/S1473-3099(11)70262-6
- Wolkewitz M, Cooper B, Palomar-Martinez M, Olaechea-Astigarraga P, Alvarez-Lerma F, Schumacher M: Nested case-control studies in cohorts with competing events. Epidemiology, 2014; 25: 122-125. : http://dx.doi.org/10.1097/EDE.0000000000000029
- Wolkewitz M, Cooper BS, Bonten MJM, Barnett AG, Schumacher M: Interpreting and comparing risks in the presence of competing events. Bmj-brit Med J, 2014; 349 (online): g5060. : http://dx.doi.org/10.1136/bmj.g5060
- Wolkewitz M, Cooper BS, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Barnett AG, Harbarth S, Schumacher M: Multilevel competing risk models to evaluate the risk of nosocomial infection. Crit Care, 2014; 18 (online): R64. : http://dx.doi.org/10.1186/cc13821
- Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Environmental contamination as an important route for the transmission of the hospital pathogen VRE: Modeling and prediction of classical interventions. Infectious Diseases: Research and Treatment, 2008; 1: 3-11.
- Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J: Statistical epidemic modeling with hospital outbreak data. Stat Med, 2008; 27: 6522-6531. : http://dx.doi.org/10.1002/sim.3419
- Wolkewitz M, Frank U, Philips G, Schumacher M, Davey P, on behalf of the BURDEN study group†: Mortality associated with in-hospital bacteraemia caused by Staphylococcus aureus: a multistate analysis with follow-up beyond hospital discharge. J Antimicrob Chemoth, 2011; 66: 381-386. : http://dx.doi.org/10.1093/jac/dkq424
- Wolkewitz M, Rothebacher D, Low M, Stegmaier C, Ziegler H, Radulescu M, Brenner H, Diepgen TL: Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly subjects: results of the ESTHER study. Brit J Dermatol, 2007; 156: 693-697.
- Wolkewitz M, Schumacher M: Simulating and analysing infectious disease data in a heterogeneous population with migration. Comput Meth Prog Bio, 2011; 104: 29-36. : http://dx.doi.org/10.1016/j.cmpb.2010.05.007
- Wolkewitz M, Vonberg RP, Grundmann H, Beyersmann J, Gastmeier P, Bärwolff S, Geffers C, Behnke M, Rüden H, Schumacher M: Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care, 2008; 12 (online): R44. : http://dx.doi.org/10.1186/cc6852
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