Forschungsbericht für das Jahr 2014

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Abouassi T, Hannig C, Mahncke K, Karygianni L, Wolkewitz M, Hellwig E, Al-Ahmad1 A: Does human saliva decrease the antimicrobial activity of chlorhexidine against oral bacteria? BMC Research Notes, 2014; 7 (online): 711. : http://dx.doi.org/10.1186/1756-0500-7-711
  • Abouassi T, Woelber JP, Holst K, Stampf S, Doerfer CE, Hellwig E, Ratka-Krüger P: Clinical efficacy and patients' acceptance of a rubber interdental bristle. A randomized controlled trial. Clin Oral Invest, 2014; 18: 1873-1880. : http://dx.doi.org/10.1007/s00784-013-1164-3
  • Allignol A, Beyersmann J, Gerds T, Latouche A: A competing risks approach for nonparametric estimation of transition probabilities in a non-Markov illness-death model. Lifetime Data Anal, 2014; 20: 495-513. : http://dx.doi.org/10.1007/s10985-013-9269-1
  • Bateli M, Kern M, Wolkewitz M, Strub JR, Att W: A retrospective evaluation of teeth restored with zirconia ceramic posts: 10-year results. Clin Oral Invest, 2014; 18: 1181-1187. : http://dx.doi.org/10.1007/s00784-013-1065-5
  • Beyersmann J, Gastmeier P, Schumacher M: Incidence in ICU populations: how to measure and report it? Intens Care Med, 2014; 40: 871-876. : http://dx.doi.org/10.1007/s00134-014-3279-7
  • Bierbaum S, Forster J, Berner R, Rücker G, Rohde G, Neumann-Haefelin D, Panning M: Detection of respiratory viruses using a multiplex real-time PCR assay in Germany, 2009/10. Arch Virol, 2014; 159: 669-676. : http://dx.doi.org/10.1007/s00705-013-1876-3
  • Binder N, Gerds TA, Andersen PK: Pseudo-observations for competing risks with covariate dependent censoring. Lifetime Data Anal, 2014; 20: 303-315. : http://dx.doi.org/10.1007/s10985-013-9247-7
  • Binder N, Schumacher M: Missing information caused by death leads to bias in relative risk estimates. J Clin Epidemiol, 2014; 67: 1111-1120. : http://dx.doi.org/10.1016/j.jclinepi.2014.05.010
  • Bleses D, Højen A, Dybdal L, Dale P, Justice L, Piasta S, Markussen-Brown J, Clausen M, Haghish EF, Ari BA, Andersen MK, Vach W: A Randomized Controlled Trial of a Large Scale Systematic and Explicit Language and Literacy Intervention in Danish Daycares: The SPELL Study. [Study Protocol]. British Journal of Education, Society and Behavioural Science, 2014; 4 (11): 1504-1524. : http://dx.doi.org/10.9734/BJESBS/2014/11691
  • Blümle A, Meerpohl JJ, Schumacher M, von Elm E: Fate of clinical research studies after ethical approval – follow-up of study protocols until publication. Plos One, 2014; 9 (online): e87184. : http://dx.doi.org/10.1371/journal.pone.0087184
  • Böhringer D, Ihorst G, Grotejohann B, Maurer J, Spierings E, Reinhard T: Functional antigen matching in corneal transplantation: matching for the HLA-A, -B and -DRB1 antigens (FANCY) - study protocol. Bmc Ophthalmol, 2014; 14 (1) (online): 156. : http://dx.doi.org/10.1186/1471-2415-14-156
  • Böhringer D, Vach W, Hagenlocher K, Eberwein P, Maier P, Reinhard T: Are entry criteria for cataract surgery justified? Plos One, 2014; 9 (11) (online): e112819. : http://dx.doi.org/10.1371/journal.pone.0112819
  • Borde JP, Batin N, Rieg S, Feik R, Reimling C, Kern WV, de With K, Hübner J, Ruhnke M, Kaier K: Adherence to an antibiotic stewardship bundle targeting Staphylococcus aureus blood stream infections at a 200-bed community hospital. Infection, 2014; 42 (4): 713-719. : http://dx.doi.org/10.1007/s15010-014-0633-1
  • Borde JP, Kaier K, Steib-Bauert M, Vach W, Geibel-Zehender A, Busch H, Bertz H, Hug M, de With K *, Kern WV *: Feasibility and impact of an intensified antibiotic stewardship programme targeting cephalosporin and fluoroquinolone use in a tertiary care university medical center. Bmc Infect Dis, 2014; 14 (online): 201. : http://dx.doi.org/10.1186/1471-2334-14-201
  • Braun M, Brandt AU, Schulz S, Boeker M: Validating archetypes for the Multiple Sclerosis Functional Composite. Bmc Med Inform Decis, 2014; 14 (1) (online): 64. : http://dx.doi.org/10.1186/1472-6947-14-64
  • Buchholz A, Sauerbrei W, Royston P: A measure for assessing functions of time-varying effects in survival analysis. Open Journal of Statistics, 2014; 4: 977-998. : http://dx.doi.org/10.4236/ojs.2014.411092
  • Bühlmann P, Gertheiss J, Hieke S, Kneib T, Ma S, Schumacher M, Tutz G, Wang C-Y, Wang Z, Ziegler A: Discussion of “The Evolution of Boosting Algorithms” and “Extending Statistical Boosting”. Method Inform Med, 2014; 53: 436-445. : http://dx.doi.org/10.3414/13100122
  • Chrubasik-Hausmann S, Chrubasik C, Walz B, Schulte-Mönting J, Erne P: Comparisons of home and daytime ambulatory blood pressure measurements. Bmc Cardiovasc Disor, 2014; 14 (online): 94. : http://dx.doi.org/10.1186/1471-2261-14-94
  • De Bin R, Sauerbrei W, Boulesteix A-L: Investigating the prediction ability of survival models based on both clinical and omics data: two case studies. Stat Med, 2014; 33: 5310-5329. : http://dx.doi.org/10.1002/sim.6246
  • Dersch R, Freitag MH, Schmidt S, Sommer H, Rücker G, Rauer S, Meerpohl JJ: Efficacy and safety of pharmacological treatments for neuroborreliosis—protocol for a systematic review. Systematic Reviews, 2014; 3 (online): 117. : http://dx.doi.org/10.1186/2046-4053-3-117
  • Diener MK, Fitzmaurice C, Schwarzer G, Seiler CM, Hüttner FJ, Antes G, Knaebel HP, Büchler MW: Pylorus-preserving pancreaticoduodenectomy (ppWhipple) versus pancreaticoduodenectomy (classicWhipple) for surgical treatment of periampullary and pancreatic carcinoma (Review). Cochrane Db Syst Rev, 2014; 11: CD006053. : http://dx.doi.org/10.1002/14651858.CD006053.pub5
  • Doerken S, Mockenhaupt M, Schumacher M, Sekula P: Assessment of the “Case-Chaos” design as an adjunct to the case-control design. Am J Epidemiol, 2014; 179: 775-780. : http://dx.doi.org/10.1093/aje/kwt310
  • Doll C, Duncker-Rohr V, Rücker G, Mix M, MacManus M, De Ruysscher D, Vogel W, Eriksen JG, Oyen W, Grosu A-L, Weber W, Nestle U: Influence of experience and qualification on PET-based target volume delineation. Strahlenther Onkol, 2014; 190: 555-562. : http://dx.doi.org/10.1007/s00066-014-0644-y
  • Duque-Ramos A, Boeker M, Jansen L, Schulz S, Iniesta M, Fernandez-Breis JT: Evaluating the Good Ontology Design Guideline (GoodOD) with the Ontology Quality Requirements and Evaluation Method and Metrics (OQuaRE). Plos One, 2014; 9 (8) (online): e104463. : http://dx.doi.org/10.1371/journal.pone.0104463
  • Ekkernkamp E, Kabitz H-J, Walker DJ, Schmoor C, Storre JH, Windisch W, Dreher M: Minute ventilation during spontaneous breathing, high-intensity noninvasive positive pressure ventilation and intelligent volume assured pressure support in hypercapnic COPD. Copd, 2014; 11: 52-58. : http://dx.doi.org/10.3109/15412555.2013.829437
  • Erbes T, Orlowska-Volk M, zur Hausen A, Rücker G, Mayer S, Voigt M, Farthmann J, Iborra S, Hirschfeld M, Meyer PT, Gitsch G, Stickeler E: Neoadjuvant chemotherapy in breast cancer significantly reduces number of yielded lymph nodes by axillary dissection. Bmc Cancer, 2014; 14 (online): 4. : http://dx.doi.org/10.1186/1471-2407-14-4
  • Farthmann J, Gabriel B, Niesel A, Fünfgeld C, Krauss A, Lenz F, Augenstein HJ, Graf E, Watermann D: Pelvic floor related quality of life after vaginal mesh implantation. Secondary endpoint of a prospective randomized trial. Pelviperineology, 2014; 33: 74-79. (download: http://www.pelviperineology.org/september-2014/pdf/pelviperineology-september-2014.pdf)
  • Fichter CD, Timme S, Braun JA, Gudernatsch V, Schöpflin A, Bogatyreva L, Geddert H, Faller G, Klimstra D, Tang L, Hauschke D, Werner M, Lassmann S: EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer. Int J Cancer, 2014; 135: 1517-1530. : http://dx.doi.org/10.1002/ijc.28771
  • Frisch E, Ziebolz D, Vach K, Ratka-Krüger P: Supportive post-implant therapy: patient compliance rates and impacting factors: 3-year follow-up. J Clin Periodontol, 2014; 41: 1007-1014. : http://dx.doi.org/10.1111/jcpe.12298
  • Genin E, Chen D-P, Hung S-I, Sekula P, Schumacher M, Chang P-Y, Tsai S-H, Wu T-L, Bellón T, Tamouza R, Fortier C, Toubert A, Charron D, Hovnanian A, Wolkenstein P, Chung W-H, Mockenhaupt M, Roujeau J-C: HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis. Pharmacogenomics J, 2014; 14: 281-288. : http://dx.doi.org/10.1038/tpj.2013.40
  • Gladstone BP, Vach W: Choice of Non-Inferiority (NI) Margins Does Not Protect against Degradation of Treatment Effects on an Average - An Observational Study of Registered and Published NI Trials. Plos One, 2014; 9 (7) (online): e103616. : http://dx.doi.org/10.1371/journal.pone.0103616
  • Grohmann J, Höhn R, Fleck T, Schmoor C, Stiller B: Transcatheter closure of atrial septal defects in children and adolescents: Single-center experience with the GORE® septal occluder. Catheter Cardio Inte, 2014; 84: E51-E57. : http://dx.doi.org/10.1002/ccd.25494
  • Guess PC, Selz CF, Voulgarakis A, Stampf S, StappertCFJ: Prospective clinical study of press-ceramic overlap and full veneer restorations: 7-year results. Int J Prosthodont, 2014; 27: 355-358. : http://dx.doi.org/10.11607/ijp.3679
  • Guess PC, Vagkopoulou T, Zhang Y, Wolkewitz M, Strub JR: Marginal and internal fit of heat pressed versus CAD/CAM fabricated all-ceramic onlays after exposure to thermo-mechanical fatigue. J Dent, 2014; 42: 199-209. : http://dx.doi.org/10.1016/j.jdent.2013.10.002
  • Haghish EF, Heydari A, Pfuhl G, Biegler R, Teymoori A: The Scale of Ethical Attitude toward Ethnic Humor (EATEH): Development, Reliability, and Validity. Asian Social Science, 2014; 10 (1): 74-85. : http://dx.doi.org/10.5539/ass.v10n1p74
  • Haun MW, Estel S, Rücker G, Friederich H, Thomas M, Hartmann M: Early palliative care for improving quality of life and survival time in adults with advanced cancer. Cochrane Db Syst Rev, 2014; 5 (online): CD011129. : http://dx.doi.org/10.1002/14651858.CD011129
  • Heydari A, Teymoori A, Haghish EF, Mohamadi B: Influential factors on ethnocentrism: The effect of socioeconomic status, anomie, and authoritarianism. Soc Sci Inform, 2014; 53 (2): 240-254. : http://dx.doi.org/10.1177/0539018413517521
  • Hieke S, Binder H, Nieters A, Schumacher M: minPtest: a resampling based gene region-level testing procedure for genetic case-control studies. Computation Stat, 2014; 29: 51-63. : http://dx.doi.org/10.1007/s00180-012-0391-4
  • Jabbarli R, Shah M, Taschner C, Kaier K, Hippchen B, Van Velthoven V: Clinical utility and cost-effectiveness of CT-angiography in the diagnosis of nontraumatic subarachnoid hemorrhage. Neuroradiology, 2014; 56 (10): 817-824. : http://dx.doi.org/10.1007/s00234-014-1406-3
  • Jeserich M, Olschewski M, Kimmel S, Bode C, Geibel A: Acute results and long-term follow-up of patients with accompanying myocarditis after viral respiratory or gastrointestinal tract infection. Int J Cardiol, 2014; 174: 853-855. : http://dx.doi.org/10.1016/j.ijcard.2014.04.196
  • Jilg CA, Schultze-Seemann W, Drendel V, Vach W, Wieser G, Krauss T, Jandausch A, Hölz S, Henne K, Reske SN, Grosu AL, Weber WA, Rischke HC: Detection of Lymph Node Metastasis in Patients with Nodal Prostate Cancer Relapse Using F/C-Choline Positron Emission Tomography/Computerized Tomography. J Urology, 2014; 192 (1): 103-111. : http://dx.doi.org/10.1016/j.juro.2013.12.054
  • Jones A, Gladstone BP, Lübeck M, Lindekilde N, Upton D, Vach W: Motivational interventions in the management of HbA1c levels: A systematic review and meta-analysis. Prim Care Diabetes, 2014; 8 (2): 91-100. : http://dx.doi.org/10.1016/j.pcd.2014.01.009
  • Kaier K, Lambert ML, Frank UK, Vach W, Wolkewitz M, Tacconelli E, Rello J, Theuretzbacher U, Martin M: Impact of availability of guidelines and active surveillance in reducing the incidence of ventilator-associated pneumonia in Europe and worldwide. Bmc Infect Dis, 2014; 14 (online): 199. : http://dx.doi.org/10.1186/1471-2334-14-199
  • Kakourou A, Vach W, Martens B: Combination Approaches Improve Predictive Performance of Diagnostic rules for Mass-Spectrometry Proteomic Data. J Comput Biol, 2014; 21 (12): 898-914. : http://dx.doi.org/10.1089/cmb.2014.0125
  • Karygianni L, Krengel M, Winter M, Stampf S, Wrbas KT: Comparative assessment of the incidence of vertical root fractures between conventional versus surgical endodontic retreatment. Clin Oral Invest, 2014; 18: 2015-2021. : http://dx.doi.org/10.1007/s00784-013-1182-1
  • Karygianni L, Ruf S, Follo M, Hellwig E, Bucher M, Anderson AC, Vach K, Al-Ahmad A: Novel Broad-Spectrum Antimicrobial Photoinactivation of In Situ Oral Biofilms by Visible Light plus Water-Filtered Infrared A. Appl Environ Microb, 2014; 80: 7324-7336. : http://dx.doi.org/10.1128/AEM.02490-14
  • Kasenda B, Sauerbrei W, Royston P, Briel M: Investigation of continuous effect modifiers in a meta-analysis on higher versus lower PEEP in patients requiring mechanical ventilation - protocol of the ICEM study. Systematic Reviews, 2014; 3 (online): 46. : http://dx.doi.org/10.1186/2046-4053-3-46
  • Kasenda B, Schandelmaier S, Sun X, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KAO, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M: Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications. Bmj-brit Med J, 2014; 349 (online): g4539-g4539. : http://www.bmj.com/content/349/bmj.g4539.full.pdf+html
  • Kasenda B, von Elm E, You J, Blumle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-Gonzalez I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Schandelmaier S, Xin S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens L, Bucher HC, Guyatt GH, Briel M, Miscellaneous: Prevalence, Characteristics, and Publication of Discontinued Randomized Trials. Jama-j Am Med Assoc, 2014; 311: 1045-1052. : http://dx.doi.org/10.1001/jama.2014.1361
  • Kirschner J, Schorling D, Hauschke D, Rensing-Zimmermann C, Wein U, Grieben U, Schottmann G, Schara U, Konrad K, Müller-Felber W, Thiele S, Wilichowski E, Hobbiebrunken E, Stettner GM, Korinthenberg R: Somatropin treatment of spinal muscular atrophy: A placebo-controlled, double-blind crossover pilot study. Neuromuscular Disord, 2014; 24: 134-142. : http://dx.doi.org/10.1016/j.nmd.2013.10.011
  • Kongsted A, Vach W, Axo M, Bech RN, Hestbaek L: Expectation of recovery from low back pain- A longitudinal cohort study investigating patient characteristics related to expectations and the association between expectations and 3-month outcome. Spine, 2014; 39: 81-90. : http://dx.doi.org/10.1097/BRS.0000000000000059
  • Kunath F, Grobe HR, Rücker G, Motschall E, Antes G, Dahm P, Wullich B, Meerpohl JJ: Non-steroidal antiandrogen monotherapy compared with luteinising hormone-releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer. Cochrane Db Syst Rev, 2014; 6 (online): CD009266. : http://dx.doi.org/10.1002/14651858.CD009266.pub2
  • Lins S, Hayder-Beichel D, Kunath F, Cartwright R, Motschall E, Antes G, Rücker G: Pelvic floor muscle training versus other active treatments for urinary incontinence in women. [Protocol] Cochrane Db Syst Rev, 2014; 6: CD007173. : http://dx.doi.org/10.1002/14651858.CD007173.pub3
  • Lins S, Hayder-Beichel D, Rücker G, Motschall E, Antes G, Meyer G, Langer G: Efficacy and experiences of telephone counselling for informal carers of people with dementia. Cochrane Db Syst Rev, 2014; 9 (online): CD009126. : http://dx.doi.org/10.1002/14651858.CD009126.pub2
  • May AM, Frey A-V, Bogatyreva L, Benkisser-Petersen M, Hauschke D, Lübbert M, Wäsch R, Werner M, Hasskarl J, Lassmann S: ID2 and ID3 protein expression mirrors granulopoietic maturation and discriminates between acute leukemia subtypes. Histochem Cell Biol, 2014; 141: 431-440. : http://dx.doi.org/10.1007/s00418-013-1169-7
  • Meerpohl JJ, Schell LK, Rücker G, Fleeman N, Motschall E, Niemeyer CM, Bassler D: Deferasirox for managing iron overload in people with myelodysplastic syndrome. Cochrane Db Syst Rev, 2014; 10 (online): CD007461. : http://dx.doi.org/10.1002/14651858.CD007461.pub3
  • Meerpohl JJ, Schell LK, Rücker G, Motschall E, Fleeman N, Niemeyer CM, Bassler D: Deferasirox for managing transfusional iron overload in people with sickle cell disease. Cochrane Db Syst Rev, 2014; 5 (online): CD007477. : http://dx.doi.org/10.1002/14651858.CD007477.pub3
  • Mueller KF, Briel M, Strech D, Meerpohl JJ, Lang B, Motschall E, Gloy V, Lamontagne F, Bassler D: Dissemination bias in systematic reviews of animal research: a systematic review. Plos One, 2014; 9 (12) (online): e116016. : http://dx.doi.org/10.1371/journal.pone.0116016
  • Navarini AA, Valeyrie-AllanoreL, Setta-Kaffetzi N, Barker JN, Capon F, Creamer D, Roujeau J-C, Sekula P, Simpson MA, Trembath RC, Mockenhaupt M, Smith CH: Generalized pustular eruptions: time to adapt the disease taxonomy to the genetic architecture? J Invest Dermatol, 2014; 134: 580-581. : http://dx.doi.org/10.1038/jid.2013.349
  • Nold SL, Horvath SD, Stampf S, Blatz MB: Analysis of select facial and dental esthetic parameters. Int J Periodont Rest, 2014; 34: 623-629. : http://dx.doi.org/10.11607/prd.1969
  • Olivier CB, Schnabel K, Brandt C, Weik P, Olschewski M, Qian Zhou Q, Bode C, Diehl P, Moser M: A high ratio of ADP–TRAP induced platelet aggregation is associated more strongly with increased mortality after coronary stent implantation than high conventional ADP induced aggregation alone. Clin Res Cardiol, 2014; 103: 968-975. : http://dx.doi.org/10.1007/s00392-014-0737-8
  • Patzelt SBM, Bishti S, Stampf S, Att W: Accuracy of computer-aided design/computer-aided manufacturing–generated dental casts based on intraoral scanner data. J Am Dent Assoc, 2014; 145: 1133-1140. : http://dx.doi.org/10.14219/jada.2014.87
  • Patzelt SBM, Emmanouilidi A, Stampf S, Strub JR, Att W: Accuracy of full-arch scans using intraoral scanners. Clin Oral Invest, 2014; 18: 1687-1694. : http://dx.doi.org/10.1007/s00784-013-1132-y
  • Patzelt SBM, Lamprinos C, Stampf S, Att W: The time efficiency of intraoral scanners: An in vitro comparative study. J Am Dent Assoc, 2014; 145: 542-551. : http://dx.doi.org/10.14219/jada.2014.23
  • Patzelt SBM, Schaible LK, Stampf S, Kohal RJ: Software-based evaluation of human attractiveness: A pilot study. J Prosthet Dent, 2014; 112: 1176-1181. : http://dx.doi.org/10.1016/j.prosdent.2014.06.013
  • Peter HH, Goldacker S, Haraldseide J, Großmann K, Gross W, Warnatz K, Grimbacher B, Rusch S, Nieters A, Vach W: Construction and Clinical Validation of a Questionnaire-based Risk Score to Identify Patients Suffering from Immunodeficiency or Systemic Autoimmunity. British Journal of Medicine & Medical Research, 2014; 4 (29): 4751-4769. : http://dx.doi.org/10.9734/BJMMR/2014/10823
  • Peter J, Abdulkadir A, Kaller C, Kümmerer D, Hüll M, Vach W, Klöppel S: Subgroups of Alzheimer's Disease: Stability of Empirical Clusters Over Time. J Alzheimers Dis, 2014; 42 (2): 651-661. : http://dx.doi.org/10.3233/JAD-140261
  • Philipsen A, Graf E, Jans T, Matthies S, Borel P, Colla M, Gentschow L, Langner D, Jacob C, Groß-Lesch S, Sobanski E, Alm B, Schumacher-Stien M, Roesler M, Retz W, Retz-Junginger P, Kis B, Abdel-Hamid M, Heinrich V, Huss M, Kornmann C, Bürger A, Tebartz van Elst L, Berger M: A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample. ADHD Attention Deficit and Hyperactivity Disorders, 2014; 6: 35-47. : http://dx.doi.org/10.1007/s12402-013-0120-z
  • Proksch S, Steinberg T, Vach K, Hellwig E, Tomakidi P: Shaping oral cell plasticity to osteogenic differentiation by human mesenchymal stem cell coculture. Cell Tissue Res, 2014; 356: 159-170.
  • Proksch S, Strobel SL, Vach K, Abouassi T, Tomakidi P, Ratka-Krüger P, Hellwig E: Melatonin as a candidate therapeutic drug for protecting bone cells from chlorhexidine-induced damage. J Periodontol, 2014; 85: e379-e389. : http://dx.doi.org/10.1902/jop.2014.140279
  • Reinhard M, Schwarzer G, Briel M, Altamura C, Palazzo P, King A, Bornstein NM, Petersen N, Motschall E, Hetzel A, Marshall RS, Klijn CJ, Silvestrini M, Markus HS, Vernieri F: Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease. Neurology, 2014; 83 (16): 1424-1431. : http://dx.doi.org/10.1212/WNL.0000000000000888
  • Rischke HC, Beck T, Vach W, Wieser G, Grosu AL, Schultze-Seemann W, Meyer PT, Jilg CA: Furosemide diminishes 18F-fluoroethylcholine uptake in prostate cancer in vivo. Eur J Nucl Med Mol I, 2014; 41 (11): 2074-2082. : http://dx.doi.org/10.1007/s00259-014-2829-0
  • Royston P, Sauerbrei W: Interaction of treatment with a continuous variable: simulation study of power for several methods of analysis. Stat Med, 2014; 33: 4695-4708. : http://dx.doi.org/10.1002/sim.6308
  • Rücker G, Schwarzer G: Reduce dimension or reduce weights? Comparing two approaches to multi-arm studies in network meta-analysis. Stat Med, 2014; 33: 4353-4369. : http://dx.doi.org/10.1002/sim.6236
  • Rücker G, Schwarzer G: Presenting simulation results in a nested loop plot. Bmc Med Res Methodol, 2014; 14 (online): 129. : http://dx.doi.org/10.1186/1471-2288-14-129
  • Rüsch N, Abbruzzese E, Hagedorn E, Hartenhauer D, Kaufmann I, Curschellas J, Ventling S, Zuaboni G, Bridler R, Olschewski M, Kawohl W, Rössler W, Kleim B, Corrigan PW: Efficacy of Coming Out Proud to reduce stigma's impact among people with mental illness: pilot randomised controlled trial. Brit J Psychiat, 2014; 204: 391-397. : http://dx.doi.org/10.1192/bjp.bp.113.135772
  • Sariyar M, Schumacher M, Binder H: A boosting approach for adapting the sparsity of risk prediction signatures based on different molecular levels. Stat Appl Genet Mol, 2014; 13: 343-357. : http://dx.doi.org/10.1515/sagmb-2013-0050
  • Sauerbrei W, Abrahamowicz M, Altman DG, le Cessie S, Carpenter J, and on behalf of the STRATOS initiative: STRengthening Analytical Thinking for Observational Studies: the STRATOS initiative. Stat Med, 2014; 33: 5413-5432. : http://dx.doi.org/10.1002/sim.6265
  • Schmucker C, Schell LK, Portalupi S, Oeller P, Cabrera L, Bassler D, Schwarzer G, Scherer RW, Antes G, von Elm E, Meerpohl JJ, on behalf of the OPEN consortium: Extent of Non-Publication in Cohorts of Studies Approved by Research Ethics Committees or Included in Trial Registries. Plos One, 2014; 9 (online): e114023. : http://dx.doi.org/10.1371/journal.pone.0114023
  • Schoenthaler M, Miernik A, Offner K, Karcz WK, Hauschke D, Sevcenco S, Kuehhas FE, Bach C, Buchholz N, Wilhelm K: The cumulative analgesic consumption score (CACS): evaluation of a new score to describe postsurgical analgesic consumption as a surrogate parameter for postoperative pain and invasiveness of surgical procedures. Int Braz J Urol, 2014; 40: 330-336. : http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.03.06
  • Schulz S, Richardt G, Laugwitz KL, Mehran R, Gershlick AH, Morath T, Mayer K, Neudecker J, Tölg R, Ibrahim T, Hauschke D, Braun D, Schunkert H, Kastrati A, Mehilli J, for the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 Investigators: Comparison of prasugrel and bivalirudin vs clopidogrel and heparin in patients with ST-segment elevation myocardial infarction: design and rationale of the bavarian reperfusion alternatives evaluation (BRAVE) 4 trial. Clin Cardiol, 2014; 37: 270-276. : http://dx.doi.org/10.1002/clc.22268
  • Schünemann HJ, Wiercioch W, Etxeandia I, Falavigna M, Santesso N, Mustafa R, Ventresca M, Brignardello-Petersen R, Laisaar KT, Kowalski S, Baldeh T, Zhang Y, Raid U, Neumann I, Norris SL, Thornton J, Harbour R, Treweek S, Guyatt G, Alonso-Coello P, Reinap M, Brozek J, Oxman A, Akl EA: Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. Can Med Assoc J, 2014; 186 (3): E123-E142. : http://dx.doi.org/10.1503/cmaj.131237
  • Schwander B, Banz K, Kaier K, Walzer S: Evaluation of a possible predictor for Federal Joint Committee decisions on early benefit assessments according to the German act on the reform of the market for medicinal products. Health Policy, 2014; 117 (3): 334-344. : http://dx.doi.org/10.1016/j.healthpol.2014.07.002
  • Sejersen T, Del Giovane C, Filippini G, Leo CG, Meerpohl JJ, Mincarone P, Minozzi S, Saverio S, Schünemann H, Senecat J, Taruscio D, RARE-Bestpractices consortium: Methodology for production of best practice guidelines for rare diseases. Rare Diseases and orphan drugs, 2014; 1: 10-19.
  • Selz CF, Strub JR, Vach K, Guess PC: Long-term performance of posterior InCeram Alumina crowns cemented with different luting agents: a prospective, randomized clinical split-mouth study over 5 years. Clin Oral Invest, 2014; 18: 1695-1703. : http://dx.doi.org/10.1007/s00784-013-1137-6
  • Siepe B, Hoilund-Carlsen PF, Gerke O, Weber WA, Motschall E, Vach W: The Move from Accuracy Studies to Randomized Trials in PET: Current Status and Future Directions. J Nucl Med, 2014; 55 (8): 1228-1234. : http://dx.doi.org/10.2967/jnumed.113.127076
  • Singer S, Meyer A, Wienholz S, Briest S, Brown A, Dietz A, Binder H, Jonas S, Papsdorf K, Stolzenburg JU, Kohler U, Rassler J, Zwerenz R, Schroter K, Mehnert A, Lobner M, Konig HH, Riedel-Heller SG: Early retirement in cancer patients with or without comorbid mental health conditions: a prospective cohort study. Cancer-am Cancer Soc, 2014; 120 (14): 2199-2206. : http://dx.doi.org/10.1002/cncr.28716
  • Storre JH, Huttmann SE, Ekkernkamp E, Walterspacher S, Schmoor C, Dreher M, Windisch W: Oxygen supplementation in noninvasive home mechanical ventilation: The crucial roles of CO2 exhalation systems and leakages Resp Care, 2014; 59: 113-120. : http://dx.doi.org/10.4187/respcare.02596
  • Storre JH, Matrosovich E, Ekkernkamp E, Walker DJ, Schmoor C, Dreher M, Windisch W: Home mechanical ventilation for COPD: High-intensity versus target volume noninvasive ventilation. Resp Care, 2014; 59: 1389-1397. : http://dx.doi.org/10.4187/respcare.02941
  • Stratz C, Nührenberg T, Fiebich BL, Amann M, Kumar A, Binder H, Hoffmann I, Valina C, Hochholzer W, Trenk D, Neumann F-J: Controlled type II diabetes mellitus has no major influence on platelet micro-RNA expression Results from micro-array profiling in a cohort of 60 patients. Thromb Haemostasis, 2014; 111: 902-911. : http://dx.doi.org/10.1160/TH13-06-0476
  • Streckmann F, Kneis S, Leifert JA, Baumann FT, Kleber M, Ihorst G, Herich L, Grüssinger V, Gollhofer A, Bertz H: Exercise program improves therapy-related side-effects and quality of life in lymphoma patients undergoing therapy. Ann Oncol, 2014; 25: 493-499. : http://dx.doi.org/10.1093/annonc/mdt568
  • Taruscio D, Morciano C, Laricchiuta P, Mincarone P, Palazzo F, Leo CG, Sabina S, Guarino R, Auld J, Sejersen T, Gavhed D, Ritchie K, Hilton-Boon M, Manson J, Kanavos PG, Nicod E, Tordrup D, Angelis A, Cam YL, Ensini M, Senecat J, Filippini G, Minozzi S, Del Giovane C, Schünemann H, Meerpohl JJ, Prediger B, Schell L, Stefanov R, Ikrov G, Miteva-Katrandzhieva T, Serrano-Aguilar P, Perestelo-Perez L, Trujillo-Martín MM, Pérez-Ramos J, Rivero-Santana A, Brand A, Lal J, van Kranen H, Bushby K, Atalaia A, Ramet J, Siderius L, Posada M, Abaitua-Borda I, Alonso Ferreira V, Hens-Pérez M, Pérez15: RARE-Bestpractices: a platform for sharing best practices for the management of rare diseases. Rare Diseases and Orphan Drugs, 2014; 1: 5-9.
  • Tchorz JP, Ganter PA, Woelber JP, Stampf S, Hellwig E, Altenburger MJ: Evaluation of an improved endodontic teaching model: do preclinical exercises have an influence on the technical quality of root canal treatments? Int Endod J, 2014; 47: 410-415. : http://dx.doi.org/10.1111/iej.12162
  • Tchorz JP, Poxleitner PJ, Stampf S, Patzelt SB, Rottke D, Hellwig E, Altenburger MJ: The use of cone beam computed tomography to predetermine root canal lengths in molar teeth: a comparison between two-dimensional and three-dimensional measurements. Clin Oral Invest, 2014; 18: 1129-1133. : http://dx.doi.org/10.1007/s00784-013-1064-6
  • Timme S, Ihde S, Fichter CD, Waehle V, Bogatyreva L, Atanasov K, Kohler I, Schöpflin A, Geddert H, Faller G, Klimstra D, Tang L, Reinheckel T, Hauschke D, Busch H, Boerries M, Werner M, Lassmann S: STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas. Oncogene, 2014; 33: 3256-3266. : http://dx.doi.org/10.1038/onc.2013.298
  • Trenado C, Amtage F, Huethe F, Schulte-Mönting J, Mendez-Balbuena I, Baker SN, Baker M, Hepp-Reymond MC, Manjarrez E, Kristeva R: Suppression of Enhanced Physiological Tremor via Stochastic Noise: Initial Observations. Plos One, 2014; 9 (11) (online): e112782. : http://dx.doi.org/10.1371/journal.pone.0112782
  • Trenado C, Mendez-Balbuena I, Manjarrez E, Huethe F, Schulte-Mönting J, Feige B, Hepp-Reymond M-C, Kristeva R: Enhanced corticomuscular coherence by external stochastic noise. Front Hum Neurosci, 2014; 8 (online): 325. : http://dx.doi.org/10.3389/fnhum.2014.00325
  • Trenado C, Mikulić A, Manjarrez E, Mendez-Balbuena I, Schulte-Mönting J, Huethe F, Hepp-Reymond M-C, Kristeva R: Broad-band Gaussian noise is most effective in improving motor performance and is most pleasant. Front Hum Neurosci, 2014; 8 (online): 22. : http://dx.doi.org/10.3389/fnhum.2014.00022
  • Vach W: Quantifizierung des Ausmaßes des Zusatznutzens von neuen Arzneimitteln: "gering" – "beträchtlich" – "erheblich" – 6 Anmerkungen aus der Sicht eines Biometrikers. [Quantifying the Additional Clinical Benefit of New Medicines: Little – Considerable – Significant – 6 Remarks from a biometrician's Point of View]. Gesundheitswesen, 2014; 76 (11): 757-762. : http://dx.doi.org/ 10.1055/s-0033-1363682
  • Walter MH, Marré B, Vach K, Strub J, Mundt T, Stark H, Pospiech P, Wöstmann B, Heydecke G, Kern M, Hartmann S, Luthardt R, Huppertz J, Wolfart S, Hannak W: Management of shortened dental arches and periodontal health: 5-year results of a randomised trial. J Oral Rehabil, 2014; 41: 515-522. : http://dx.doi.org/10.1111/joor.12160
  • Wolkewitz M, Barnett AG, Palomar Martinez M, Frank U, Schumacher M, IMPLEMENT Study Group: Interventions to control nosocomial infections: study designs and statistical issues. J Hosp Infect, 2014; 86: 77-82. : http://dx.doi.org/10.1016/j.jhin.2013.09.015
  • Wolkewitz M, Cooper B, Palomar-Martinez M, Olaechea-Astigarraga P, Alvarez-Lerma F, Schumacher M: Nested case-control studies in cohorts with competing events. Epidemiology, 2014; 25: 122-125. : http://dx.doi.org/10.1097/EDE.0000000000000029
  • Wolkewitz M, Cooper BS, Bonten MJM, Barnett AG, Schumacher M: Interpreting and comparing risks in the presence of competing events. Bmj-brit Med J, 2014; 349 (online): g5060. : http://dx.doi.org/10.1136/bmj.g5060
  • Wolkewitz M, Cooper BS, Palomar-Martinez M, Alvarez-Lerma F, Olaechea-Astigarraga P, Barnett AG, Harbarth S, Schumacher M: Multilevel competing risk models to evaluate the risk of nosocomial infection. Crit Care, 2014; 18 (online): R64. : http://dx.doi.org/10.1186/cc13821
Buchbeiträge:
  • Dreier G, Jena S: Registrierung klinischer Studien. In: Christian Lenk, Gunnar Duttge, Heiner Fangerau (Hrsg.): Handbuch Ethik und Recht der Forschung am Menschen. Berlin - Heidelberg: Springer-Verlag, 2014; 643-648.: http://www.springer.com/gp/book/9783642350986
  • Sauerbrei W: Covariates. In: Wiley StatsRef: Statistics Reference Online Wiley StatsRef, 2014.: http://dx.doi.org/10.1002/9781118445112.stat06792
  • Schmoor C, Graf E: Hazard Ratio. In: Balakrishnan N (Hrsg.): Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs. Hoboken, New Jersey: John Wiley & Sons, Inc., 2014; 483-499.: http://dx.doi.org/10.1002/9781118596005.ch38
Kurzbeiträge / short communications:
Konferenzbeiträge:
  • Braun M, Kirschner J, Vach W, Boeker M: Evaluation einer Ratgeberapplikation für die Muskeldystrophie Duchenne. GMS German Medical Science, 2014 (online): 266 (59. GMDS Jahrestagung, Göttingen, 7.-10.9.2014: Big Data und Forschungsinfrastruktur - Perspektiven für die Medizin.). : http://dx.doi.org/10.3205/14gmds133
  • Droeschel D, Kaier K, Walzer S: The Clinical Evidence Base of Treatment Options in Alzheimer's Disease: a Systematic Literature Search. [Meeting Abstract PND11]. Value Health, 2014; 17 (7): A392 (ISPOR 17th Annual European Congress, Amsterdam 8.-12.11.2014). : http://dx.doi.org/10.1016/j.jval.2014.08.865
  • Gutmann A, Sorg S, von zur Mühlen C, Kaier K, Moser M, Blanke P, Beyersdorf F, Bode C, Zehender M, Reinöhl J: Interventionelle, chirurgische und medikamentöse Therapie der Aortenklappenstenose – Mortalität und Lebensqualität bei Hochrisiko-Patienten. Clin Res Cardiol, 2014; 103 Suppl. 1: P1716 (80. Jahrestagung der Deutschen Gesellschaft für Kardiologie in Mannheim, 23.-26.4.2014). : http://dx.doi.org/10.1007/s00392-014-1100-9 (download: http://www.abstractserver.de/dgk2014/ft/abstracts/P1716.HTM)
  • Kaier K, Gutmann A, Sorg S, Beyersdorf F, Vach W, Zehender M, Bode C, Reinöhl J: The Additional Costs Of Clinical Complications In Patients Undergoing Transcatheter Aortic Valve Replacement In The German Health Care System. Abstract No. PCV3. Value Health, 2014; 17 (7): A473 (ISPOR 17th Annual European Congress, Amsterdam 8.-12.11.2014.). : http://dx.doi.org/10.1016/j.jval.2014.08.1347
  • Kaier K, Gutmann A, Vach W, Sorg S, von zur Mühlen C, Geibel-Zehender A, Beyersdorf F, Bode C, Zehender M, Reinöhl J: Clinical decision-making among patients with symptomatic aortic valve stenosis – A look behind the curtain. Clin Res Cardiol, 2014; 103 Suppl. 1: P1726 (80. Jahrestagung der Deutschen Gesellschaft für Kardiologie in Mannheim, 23.-26.4.2014). : http://dx.doi.org/10.1007/s00392-014-1100-9 (download: http://www.abstractserver.de/dgk2014/ft/abstracts/P1726.HTM)
  • Pandurevic M, Selder R, Möller M, Kleber M, Pantic M, Waldschmidt J, Herget G, Henne K, Hauschild O, May A, von Bubnoff N, Duyster J, Vach W, Wäsch R, Engelhardt M: Current results on patient (pt), referring physician and participant satisfaction concerning the interdisciplinary Comprehensive Cancer Center (CCCF) Tumor Board (TB) 'Multiple Myeloma' (MM). Oncology Research and Treatment, 2014; 37 Suppl. 5: 288 (Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Hamburg, 10.-14. Oktober 2014. Meeting Abstract: P865 .). : http://dx.doi.org/10.1159/000368945
  • Reinöhl J, Kaier K, Gutmann A, Sorg S, von zur Mühlen C, Moser M, Geibel-Zehender A, Blanke P, Beyersdorf F, Bode C, Zehender M: Resource utilization and risk prediction in the treatment of symptomatic aortic valve stenosis. Clin Res Cardiol, 2014; 103 Suppl. 1: P1688 (80. Jahrestagung der Deutschen Gesellschaft für Kardiologie in Mannheim, 23.-26.4.2014). : http://dx.doi.org/10.1007/s00392-014-1100-9 (download: http://www.abstractserver.de/dgk2014/ft/abstracts/P1688.HTM)
  • Schwander B, Banz K, Kaier K, Walzer S: Is it Possible to Predict The Market Access of a New Pharmaceutical in Germany? A Systematic Evaluation of Federal Joint Committee Decisions on Early Benefit Assessments According to The German Law For Reforming The Market of Pharmaceuticals. Abstract No PHP199. Value Health, 2014; 17 (7): A437 (ISPOR 17th Annual European Congress, Amsterdam 8.-12.11.2014). : http://dx.doi.org/10.1016/j.jval.2014.08.1135
  • Selder R, Pandurevic M, Möller MD, Waldschmidt J, Pantic M, Herget GW, Henne K, May A, Kleber M, Udi J, Ihorst G, Bredenkamp R, Vach W, Duyster J, Wäsch R, Engelhardt M: First Results of the Interdisciplinary Comprehensive Cancer Center Freiburg (CCCF) Tumor Board (TB) Multiple Myeloma (MM) Assessing TB-Questions, TB-Advice Adherence, TB-Satisfaction of Patients, Participants and Referring Physicians, Inclusion of Difficult-to-Treat-MM Pts in Clinical Trials (CT) and Patient Outcome. Blood, 2014; 124 (21) (56th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, Dec 06-09, 2014). : http://www.bloodjournal.org/content/124/21/2635
  • Selder RM, Möller MD, Pandurevic M, Kleber M, Waldschmidt J, Herget GW, Henne K, Hauschild O, May AM, Pantic M, von Bubnoff N, Duyster J, Vach W, Wäsch R, Engelhardt M: First results of the interdisciplinary Comprehensive Cancer Center Freiburg (CCCF) Tumor Board (TB)-'Multiple Myeloma' (MM) in terms of TB-questions, patient (pt) outcome, TB-advice adherence and suitability of difficult-to-treat-MM pts to include in clinical trials (CT). Oncology Research and Treatment, 2014; 37 Suppl. 5: 288 (Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Hamburg, 10.-14. Oktober 2014. Meeting Abstract: P864 .). : http://dx.doi.org/10.1159/000368945
  • Walzer S, Droeschel D, Kaier K: Health Economic Models in Alzheimer's Disease: A Critical Assessment. Abstract No. PRM81. Value Health, 2014; 17 (7): A557 (ISPOR 17th Annual European Congress, Amsterdam 8.-12.11.2014). : http://dx.doi.org/10.1016/j.jval.2014.08.1833
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