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Forschungsschwerpunkte
- Direct recordings from presynaptic elements and dendrites
- Excitatory and inhibitory synaptic transmission in the mammalian central nervous system
- Functional significance of K+ channels in various types of cell (neurons, sensory hair cells in the inner ear)
- GABAergic interneurons
- Glutamate receptors of the AMPA and NMDA subtype
- Ion channels
- Ion transport
- Mechanisms of transmitter release
- Molecular mechanisms underlying function and regulation of ion channels (K+, Ca2+) and other membrane proteins (prestin)
- NMR-based structure analysis of functional domains of membrane proteins (in particular ion channel proteins)
- Protein-protein interaction in ion channels
- Proteom analysis of the microdomains associated with membrane proteins including ion channels, transporters and GPCRs
- Somatodendritic integration of synaptic signals
- Voltage-gated ion channels (Na+, K+, Ca2+)
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