Wissenschaftliche Publikationen

• Barmashenko G, Hefft S, Aertsen A, Kirschstein T, Köhling R: Positive shifts of the GABA A receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus. Epilepsia, 2011; 52 (9): 1570-1578.
• Bredel M, Scholtens DM, Yadav AK, Alvarez AA, Renfrow JJ, Chandler JP, Yu IL, Carro MS, Dai F, Tagge MJ, Ferrarese R, Bredel C, Phillips HS, Lukac PJ, Robe PA, Weyerbrock A, Vogel H, Dubner S, Mobley B, He X, Scheck AC, Sikic BI, Aldape KD, Chakravarti A, Harsh GR: NFKBIA Deletion in Glioblastomas. New Engl J Med, 2011; 364 (7): 627-637. : http://dx.doi.org/10.1056/NEJMoa1006312
• Cordeiro JG, Wagner K, Trippel M, Zentner J, Schulze-Bonhage A.: Superselective anterior temporal resection in mesial temporal lobe epilepsy. Epileptic Disord, 2011; 13 (3): 284-290.
• Firat E, Gaedicke S, Tsurumi C, Esser N, Weyerbrock A, Niedermann G: Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells Radiat Oncol, 2011; 6 (online): 71. : http://dx.doi.org/10.1186/1748-717X-6-71
• Freiman TM, Eismann-Schweimler J, Frotscher M.: Granule cell dispersion in temporal lobe epilepsy is associated with changes in dendritic orientation and spine distribution Exp Neurol, 2011; 229 (2): 332-338.
• Gierthmuehlen M, Ball T, Henle C, Wang X, Rickert J, Raab M, Freiman T, Stieglitz T, Kaminsky J: Evaluation of µECoG electrode arrays in the minipig: Experimental procedure and neurosurgical approach. J Neurosci Meth, 2011; 202 (1): 77-86.
• Gläsker S, Shah MJ, Hippchen B, Neumann HP, Van Velthoven V: Doppler-Sonographically Guided Resection of CNS Hemangioblastomas. Neurosurgery, 2011; 68 Suppl. 2: 267-274. : http://dx.doi.org/10.1227/NEU.0b013e3182124677
• Gläsker S, Vortmeyer AO, Lafferty AR, Hofman PL, Li J, Weil RJ, Zhuang Z, Oldfield EH: Hereditary Pituitary Hyperplasia with Infantile Gigantism. Clin Endocrinol, 2011; 96 (12): 2078-2087. : http://dx.doi.org/10.1210/jc.2011-1401
• Grauvogel J, Scheiwe C, Kaminsky J: Use of Piezosurgery for internal auditory canal drilling in acoustic neuroma surgery. Acta Neurochir, 2011; 153 (10): 1941-1947. : http://dx.doi.org/10.1007/s00701-011-1092-4
• Kammerer M, Brawek B, Freiman TM, Jackisch R, Feuerstein TJ: Effects of antiepileptic drugs on glutamate release from rat and human neocortical synaptosomes. N-s Arch Pharmacol, 2011; 383 (5): 531-542.
• Kammerer M, Fabritius M, Carvalho C, Mülhaupt R, Feuerstein TJ, Trittler R: Valproate release from polycaprolactone implants prepared by 3D-Bioplotting. Pharmazie, 2011; 66: 511-516.
• Kammerer M, Rassner MP, Freiman TM, Feuerstein TJ: Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes. N-s Arch Pharmacol, 2011; 384 (1): 47-57.
• Kogias E, Kircher A, Deininger MH, Psarras N, Keck T, Schäfer AO, Hubbe U: A very rare cause of low-back pain and sciatica: deep vein thrombosis due to absence of the inferior vena cava mimicking the clinical and radiological signs of lumbar disc herniation. J Neurosurg-spine, 2011; 15 (2): 164-167.
• Kogias E, Osterberg N, Baumer B, Psarras N, Koentges C, Papazoglou A, Saavedra JE, Keefer LK, Weyerbrock A: Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-p-activated nitric oxide donor PABA/NO in malignant gliomas. Int J Cancer, 2011. : http://dx.doi.org/10.1002/ijc.26106 (in Druck)
• Kogias E, Sircar R, Klingler JH, Deininger MH, Hubbe U: Retropsoas iliac artery: potential cause of complications in lumbar spine surgery. J Neurosurg-spine, 2011; 15 (2): 210-210.
• Lepski G, Maciaczyk J, Jannes CE, Maciaczyk D, Bischofberger J, Nikkhah G: Delayed functional maturation of human neuronal progenitor cells in vitro. Mol Cell Neurosci, 2011; 47 (1): 36-44.
• Maruschke L, Grauvogel J, Baumann T: Ulceration on the bridge of the nose in a young adult. Radiologe, 2011; 51 (8): 714-717.
• Psaras T, Milian M, Hattermann V, Freiman T, Gallwitz B, Honegger J: Demographic Factors and the Presence of Comorbidities do not Promote Early Detection of Cushing's Disease and Acromegaly. Exp Clin Endocr Diab, 2011; 119 (1): 21-25. : http://dx.doi.org/10.1055/s-0030-1263104
• Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG: BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model. Clin Cancer Res, 2011; 17 (11): 3590-3599.
• Renfrow JJ, Scheck AC, Dhawan NS, Lukac PJ, Vogel H, Chandler JP, Raizer JJ, Harsh GR, Chakravarti A, Bredel M: Gene-protein correlation in single cells. Neuro-oncology, 2011; 13 (8): 880-885.
• Schramm J, Lehmann TN, Zentner J, Mueller CA, Scorzin J, Fimmers R, Meencke HJ, Schulze-Bonhage A, Elger CE: Randomized controlled trial of 2.5-cm versus 3.5-cm mesial temporal resection in temporal lobe epilepsy-part 1: intent-to-treat analysis. Acta Neurochir, 2011; 153 (2): 209-219. : http://dx.doi.org/10.1007/s00701-010-0900-6
• Schramm J, Lehmann TN, Zentner J, Mueller CA, Scorzin J, Fimmers R, Meencke HJ, Schulze-Bonhage A, Elger CE: Randomized controlled trial of 2.5-cm versus 3.5-cm mesial temporal resection-part 2: volumetric resection extent and subgroup analyses. Acta Neurochir, 2011; 153 (2): 221-228. : http://dx.doi.org/10.1007/s00701-010-0901-5
• Staack AM, Bilic S, Wendling AS, Scholly J, Kraus U, Strobl K, Bodin F, Zentner J, Steinhoff BJ: Hyperkinetic seizures in patients with temporal lobe epilepsy: clinical features and outcome after temporal lobe resection. Epilepsia, 2011; 52 (8): 1439-1446. : http://doi: 10.1111/j.1528-1167.2011.03100.x. Epub 2011 May 13.
• Volz F, Bock HH, Gierthmuehlen M, Zentner J, Haas CA, Freiman TM: Stereologic estimation of hippocampal GluR2/3- and calretinin-immunoreactive hilar neurons (presumptive mossy cells) in two mouse models of temporal lobe epilepsy. Epilepsia, 2011; 52 (9): 1579-1589. : http://dx.doi.org/10.1111/j.1528-1167.2011.03086
• Weyerbrock A, Osterberg N, Psarras N, Baumer B, Kogias E, Werres A, Bette S, Saavedra JE, Keefer LK, Papazoglou A: JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas. Neurosurgery, 2011. (in Druck)
• Weyerbrock A, Walbridge S, Saavedra JE, Keefer LK, Oldfield EH: Differential effects of nitric oxide on blood-brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas. Neuro-oncology, 2011; 13 (2): 203-211. : http://dx.doi.org/10.1093/neuonc/noq161
• Wolter T, Deininger M, Hubbe U, Mohadjer M, Knoeller S: Cryoneurolysis for zygapophyseal joint pain: a retrospective analysis of 117 interventions. Acta Neurochir, 2011; 153 (5): 1011-1019.

• Fauser S, Zentner J: Management of cortical dysplasia in epilepsy. Advances and Technical Standards in Neurosurgery, 2011; 38: 137-163.
• Feuerstein TJ, Kammerer M, Lücking CH, Moser A: Selective GABA release as a mechanistic basis of high frequency stimulation used for the treatment of neuropsychiatric diseases. N-s Arch Pharmacol, 2011; 384: 1-20. : http://dx.doi.org/10.1007/s00210-011-0644-8

• Taschner CA, Staszewski O, van Velthoven V, Müller M, Kontny U, Hader C, Prinz M: Freiburg neuropathology case conference: a midline mass lesion in an infant. Clin Neuroradiol, 2011; 21 (2): 101-106.
• Taschner CA, Staszewski O, Weyerbrock A, Hader C, Prinz M: Freiburg neuropathology case conference: osteolytic lesion. Clin Neuroradiol, 2011; 21 (1): 35-39.
• Taschner CA, Staszewski O, Zentner J, Meckel S, Prinz M: Freiburg neuropathology case conference: a mass lesion of the mesial temporal lobe in a child. Clin Neuroradiol, 2011; 21 (3): 171-176.

• Heckler M, Osterberg N, Baumer B, Weyerbrock A: Nitric oxide donor JS-K intensifies cytotoxic effects of repetitive irraditation in glioma cells in vitro. 2011 (Poster bei der Brain Tumor 2011, Berlin).
• Hefft S: Single unit recordings in human with improved neurosurgical implantation technique. 2011 (Jahrestagung der Deut. Gesellschaft für Biomedizinische Technik (DGBMT), Freiburg).
• Shah MJ: The potential of using intraoperative ultrasonic 3D-navigation in Neurosurgery. 2011 (Institute of Neurosurgery, Burdenko (Moscow, Russion Federation)).
• Weyerbrock A: Tumor Profiling – neue diagnostische Ansätze mit therapeutischer Relevanz? 2011 (Veranstaltung zum Welthirntumortag 2011, Freiburg).
• Weyerbrock A: Operatives Vorgehen bei cerebralen Melanommetastasen 2011 (Symposium Melanome, Tumorzentrum Ludwig Heilmeyer, Freiburg).
• Weyerbrock A, Osterberg N, Ordikhani-Seyedlar M, Werres A, Weidensteiner C, Reichardt W: Impact of NO donor therapy with JS-K and temozolomide chemotherapy on tumor volume, perfusion and vascular permeability and survival in intracranial U87 xenografts in vivo. 2011 (Jahrestagung der Deutschen Gesellschaft für Neurochirurgie, Hamburg).
• Zentner J: Epilepsy surgery: One does all or have children specific requirements. 2011 (62. Jahrestagung der DGNC, Hamburg).
• Zentner J: Introduction and general aspects of IONM. 2011 (INOMED, Emmendingen).
• Zentner J: Epilepsiechirurgie in Freiburg - eine Leistungsstatistik. 2011 (12. Epi Symposium, Epilepsiezentrum Kork, Kehl).
• Zentner J: Gemeinsame Schädelbasischirurgie 2011 (Freiburger Herbstsymposium, Univ. HNO-Klinik,).
• Zentner J: Epilepsie im Spiegel der Kunst. Neurosurgery in Bonn. A Period Revisited. 2011 (Scientific Symposium, Bonn).

• Altenmüller D, Hebel J, Rassner M, Freiman T, Feuerstein T, Zentner J: Local application of valproate enhances survival in the novel tetanus toxin / cobalt chloride rat model of neocortical epilepsy. 2011 (Int. Liga against Epilepsy (ILAE) 2011, Rom , Italy).
• Bredel M, Scholtens A, Yadav A, Renfrow J, Chandler J, Yu I, Carro M, Dai F, Tagge M, Ferrarese R, Bredel C, Phillips HS, Robe P, Weyerbrock A, Vogel H, Scheck A, Sikic BI, Aldape KD, Chakravarti A, Harsh G.: NFKBIA deletion substitutes for EGFR amplification in glioblastoma pathogenesis. 2011 (ASCO, Chicago, USA).
• Freiman TM, Altenmüller DM, Haas CA, Feuerstein TJ, Zentner J: Local anti-epileptic therapy with valproate mini-pumps and gel in a mouse model of pharmacoresistant epilepsy 2011 (Jahrestagung d. Dt. Ges. f. Neurochir. (DGNC) 2011, Hamburg).
• Freiman TM, Altenmüller DM, Haas CA, Feuerstein TJ, Zentner J: Lokale antiepileptische Therapie mit Valproat-Minipimpen und –Gel in einem Mausmodell pharmakoresistenter Epilepsie 2011 (Jahrestagung d. Dt. Ges. f. Neurochir. (DGNC) 2011, Hamburg,).
• Freiman TM, Haas CA, Frotscher M, Zentner J: Moosfasersprossung in Hippocampi von Patienten mit Temporallappenepilepsie führt zu inhibitorischen neuronalen Rückkopplungsschleifen. 2011 (Jahrestagung d. Dt. Ges. f. Neurochir. (DGNC) 2011, Hamburg).
• Freiman TM, Jabbarli R, Kleemann T, Zhao S, Bock H, Frotscher M: Granule cell dispersion in two mouse models of temporal lobe epilepsy is associated with changes in dendritic orientation and spine distribution 2011 (4th International Epilepsy Colloquium, Marburg 2011).
• Freiman TM, Ramantani G, Zentner J: Funktionell Hemisphärotomie bei refraktärer Epilepsie: Resultate und Überlegungen. 2011 (Jahrestagung d. Dt. Ges. f. Neurochir. (DGNC) 2011, Hamburg).
• Hanuschkin A, Stegen M, Kirchheim F, Wolfart J: The function of hyperpolarization-activated channels in human dentate gyrus granule cells 2011.
• Häussler U, Bielefeld L, Froriep UP, Wolfart J, Haas CA: Neurogenesis in temporal lobe epilepsy 2011 (9th Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany).
• Häussler U, Marx M, Bielefeld L, Froriep UP, Wolfart J, Haas CA: Septotemporal position in the hippocampal formation determines epileptic activity in Temporal Lobe Epilepsy 2011.
• Heckler M, Osterberg N, Baumer B, Weyerbrock A: Nitric oxide donor JS-K intensifies cytotoxic effects of repetitive irradiation in U-87 glioma cells in vitro. 2011 (Brain Tumor 2011, Berlin).
• Hefft S: Efficacité de l‘enregistrement de potentiels d‘action isolées dans le context des bilans préchirurgicaux invasives-L‘expérience au centre des neurosciences cliniques de l‘Université de Freiburg 2011 (Journee de Neurologie de Langue Francaise, Paris, France).
• Hefft S, Cseppentö T, Augustin M, Stancheva S: Electrophysiological properties of fast spiking interneurons and principal cells in Layer II/III differ between human epileptogenic an non epileptogenic temporal cortex 2011 (2011 Meeting of the Society of Neuroscience, Washington, USA).
• Hefft S, Hamid O, Brandt A, Schulze-Bonhage A, Trippel M: Single- and Multi-unit recordings in humans at the Neurozentrum of the Albert Ludwigs University Freiburg. Front Comput Neurosc, 2011 (Conference Abstract: BC11 : Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting 2011, Freiburg, Germany). : http://dx.doi.org/10.3389/conf.fncom.2011.53.00153 (in Druck)
• Hubbe U, Sircar R: Sagittal Balance: Principle, Diagnostics and Impact on Spine Surgery 2011 (Spine Specialists Meeting 2011, Freiburg).
• Kahlert U, Maciaczyk D, Nikkhah G, Simons B, Orr B, Eberhart C, Maciaczyk J: The role of canonical WNT/ß-catenin signaling in glial tumors. 2011 (102nd AACR Annual Meeting Orlando, Florida, USA).
• Kogias E, Klingler JH, Sircar R, Scheiwe C, Deininger M, Hubbe U: Inzidenz von Duraverletzung bei der mikrochirurgischen Dekompression in 3 oder mehreren Segmenten für degenerative lumbale Spinalkanalstenose. 2011 (Deutscher Wirbelsäulenkongress, 6. Jahrestagung der Deutschen Wirbelsäulengesellschaft (DWG), Hamburg.).
• Maciaczyk J, Kahlert U, Maciaczyk D, Simons B, Orr B, Eberhart C, Nikkhah G: The role of canonical WNT/beta-catenin signaling in glial brain tumors 2011 (Jahrestagung d. Dt. Ges. f. Neurochir. (DGNC) 2011, Hamburg).
• Mao Xinggang, Raabe E, Maciaczyk J, Kahlert U, Nikkhah G, Eberhart C: LIN28 is expressed in glioblastomas and promotes KRAS-mediated transformation of human neural stem cells. 2011 (102nd AACR Annual Meeting Orlando, Florida, USA).
• Raabe E, Lim Kah Suan, Mao Xing-Gang, Bar E, Meeker A, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart C: BRAF activation induces cellular transformation and senescence and down-regulates SOX2 in human neural stem cells: a model of pilocytic astrocytoma. 2011 (102nd AACR Annual Meeting Orlando, Florida, USA).
• Rassner M, Altenmüller D, Hebel J, Feuerstein TJ, Freiman TM: Electroencephalographic recordings and their alterations through local antiepileptic polymers in a rat epilepsy model combining neocortical tetanus toxin and cobalt chloride application 2011 (4th International Epilepsy Colloquium, Marburg 2011).
• Scheiwe C, Fauser S, Zentner J: Chirurgische Behandlung extratemporaler Epilepsie: Ergebnisse bei 253 Prozeduren. 2011 (62. Jahrestagung der DGNC, Hamburg).
• Shah MJ, Sircar R, Gläsker S, van Velthoven V: Integration of 3D-doppler ultrasound in navigated neurosurgery of AVMs as an intraoperative tool for the extent of resection 2011 (CF: M0138; 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH), Hamburg).
• Sircar R, Klingler JH, Kogias E, Hubbe U: Bipolare vs. monopolare Pedikelstimulation in lumbaler perkutaner Instrumentation. 2011 (Deutscher Wirbelsäulenkongress, 6. Jahrestagung der Deutschen Wirbelsäulengesellschaft (DWG), Hamburg).
• Thiede NK, Baumer B, Osterberg N, Bette S, Weyerbrock A: NO donor JS-K enhances cytotoxic effects of radiotherapy in U87 gliomas in vitro. 2011 (Jahrestagung der Deutschen Gesellschaft für Neurochirurgie, Hamburg,).
• Weidensteiner C, Ordikhani-Seyedlar M, Werres A, Osterberg N, Weyerbrock A, Reichardt W: DCR-MRI in rat gliomas under therapy with temozolomide and a nitric oxide donor. 2011 (Jahrestagung der International Society for Magnetic Resonance in Medicine (ISMRM), Montreal).

• Feuerstein TJ: Commentary. Gabapentin-lactam and GABA-lactam analogues: The enigma of their mechanism of action. Oral Craniofac Tissue Eng, 2011; 1: 19-32.