Permanent sterile antimikrobielle Oberfächen

To overcome the deficiencies of today’s antibacterial materials, the aim of this project is to develop long-term sterile polymer surfaces that are simultaneously antibacterial and antibiofouling.

Projektbeginn: 01.01.2011
Projektende: 30.06.2017

Lienkamp K

Albert-Ludwigs-Universität Freiburg
Bioactive Polymer Synthesis and Surface Engineering
Arbeitsgruppe Dr. Lienkamp
Georges-Koehler-Allee 103
79110 Freiburg

Telefon: 95090
Email: lienkamp@imtek.uni-freiburg.de
http://www.cpi.uni-freiburg.de/polymer-synthesis-group-dr.-karen-lienkamp

Prof. Dr. Thorsten Steinberg, Uniklinikum Freiburg Prof. Dr. Ali Al-Ahmad, Uniklinikum Freiburg Prof. Dr. Zeev Rosenzweig, University of Maryland-BC, Baltimore, USA

• Emmy-Noether-Gruppe, DFG

• Hartleb, Wibke, Saar, Julia S., Zou, Peng, Lienkamp, Karen: Just Antimicrobial is not Enough: Toward Bifunctional Polymer Surfaces with Dual Antimicrobial and Protein-Repellent Functionality Macromol. Chem. Phys., 2016; 217 (2): 225-231. : http://dx.doi.org/10.1002/macp.201500266
• Franziska Dorner, David Boschert, Alexandra Schneider, Wibke Hartleb, Ali Al-Ahmad, Karen Lienkamp: Toward Self-regenerating Antimicrobial Polymer Surfaces ACS Macro Lett., 2015; 4: 1337-1340.
• Zou, Peng, Laird, Dougal, Riga, Esther K., Deng, Zhouling, Perez-Hernandez, Heidi-Rosalia, Guevara-Solarte, Diana Lorena, Steinberg, Thorsten, Al-Ahmad, Ali, Lienkamp, Karen: Antimicrobial and Cell-Compatible Surface-attached Polymer Networks – How the Correlation of Chemical Structure to Physical And Biological Data Leads to a Modified Mechanism of Action Journal of Materials Chemistry B, 2015; 3: 6224-6238. : http://pubs.rsc.org/en/content/articlepdf/2015/tb/c5tb00906e?page=search
• Al-Ahmad, Ali, Zou, Peng, Guevara-Solarte, Diana Lorena, Hellwig, Elmar, Steinberg, Thorsten, Lienkamp, Karen: Development of a standardized and safe airborne antibacterial assay, and its evaluation on antibacterial biomimetic model surfaces PLoS ONE, 2014: e111357.
• Dorner, Franziska, Lienkamp, Karen: CHAPTER 5 Polymer-Based Synthetic Mimics of Antimicrobial Peptides (SMAMPs) - A New Class of Nature-Inspired Antimicrobial Agents with Low Bacterial Resistance Formation Potential In: Polymeric Materials with Antimicrobial Activity: From Synthesis to Applications The Royal Society of Chemistry, 2014; 97-138.: http://dx.doi.org/10.1039/9781782624998-00097
• Al-Ahmad, Ali, Laird, Dougal, Zou, Peng, Tomakidi, Pascal, Steinberg, Thorsten, Lienkamp, Karen: Nature-Inspired Antimicrobial Polymers – Assessment of Their Potential for Biomedical Applications PLoS ONE, 2013; 8 (9): e73812, Public Library of Science (Hrsg). : http://dx.doi.org/10.1371%2Fjournal.pone.0073812
• Lienkamp, Karen, Madkour, Ahmad E., Tew, Gregory N.: Antibacterial peptidomimetics: polymeric synthetic mimics of antimicrobial peptides Adv. Polym. Sci., 2013; 251 (Polymer Composites, Polyolefin Fractionation, Polymeric Peptidomimetics, Collagens): 141-172. : http://link.springer.com/chapter/10.1007%2F12_2010_85
• Zou, Peng, Hartleb, Wibke, Lienkamp, Karen: It takes walls and knights to defend a castle - synthesis of surface coatings from antimicrobial and antibiofouling polymers J. Mater. Chem., 2012; 22 (37): 19579-19589.
• Lienkamp, Karen: New polymers against multi-resistant bacteria Nachrichten aus der Chemie, 2011; 59 (7/8): 719-723.