|
Priv. Doz., Dr. Marcus Frank
geb. am 24.04.1966 in Reutlingen
1993 Diplom Biologie, Universität Tübingen
1994 Staatsexamen Geschichte / Biologie, Universität Tübingen
1999 Promotion Dr. sc. nat. ETH Zürich
1999-2001 Postdoktorand Mount Sinai School of Medicine, New York
2001-2006 Laborleiter MPI für Immunbiologie, Freiburg
2006-2008 W2-Professurvertretung "Spezielle Zoologie und Evolution der Tiere", Universität Marburg.
2008 Habilitation "Entwicklungsbiologie der Tiere" Fakultät für Biologie,Universität Freiburg
2008 W3-Professurvertretung "Entwicklungsbiologie der Tiere", Universität Freiburg
 Hauptforschungsgebiete
Neuroentwicklungsbiologie, Biologie von Gliazellen, Embryologie der Wirbeltiere, Zelladhäsionsmolküle der Cadherinfamilie, insbesondere Protocadherine.
Wichtige Publikationen
Frank M., van der Haar M.E., Schaeren-Wiemers N. and M.E. Schwab (1998). rMAL is a glycosphingolipid-associated protein of myelin and apical membranes of epithelial cells in kidney and stomach. J. Neurosci. 18 (13), 4901-4913.
Frank M. (2000). MAL, a proteolipid in glycosphingolipid enriched domains: functional implications in myelin and beyond. Prog. Neurobiol. 60, 531-544.
Chen M.S.*, Huber A.B.*, van der Haar M.E.*, Frank M., Schnell L., Spillmann A.A., Christ F. and M.E. Schwab (2000). Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature 403, 434-439.
Frank M. and R. Kemler (2002). Protocadherins. Curr.Opin.Cell.Biol. 14, 557-562.
Haas I.G., Frank M., Véron N., and R. Kemler (2005). Presenilin-dependent processing and nuclear function of gamma-protocadherins J. Biol. Chem., 280, 9313-9319.
Frank M., Ebert M., Shan W.S., Phillips G.R., Arndt K., Colman D.R., and R. Kemler (2005). Differential expression of individual gamma-proto-cadherins during mouse brain development. Mol. Cell. Neurosci. 29, 603-616.
Reiss K.*, Maretzky T.*, Haas I.G., Schulte M., Ludwig A., Frank M.* and P. Saftig * (2006). Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion. J. Biol. Chem., 281, 21735-21744.
Bass T., Ebert M., Hammerschmidt M., and M. Frank (2007). Differential expression of four protocadherin alpha and gamma clusters in the developing and adult zebrafish: DrPcdh2γ but not DrPcdh1γ is expressed in neuronal precursor cells, ependymal cells and non-neuronal epithelia. Dev. Genes Evol., 217, 337-351.
Kontaktaufnahme
Email: marcus.frank@biologie.uni-freiburg.de
Adresse / Postanschrift:
Institut für Biologie I Entwicklungsbiologie Hauptstr. 1 79104 Freiburg i. Br.
Telefon: ++49 761 203 2588 Email: ebio-office@biologie.uni-freiburg.de
http://www.bio1.uni-freiburg.de/ebio
|