Prof. Dr. Ralf Reski

geb. am 18.11.1958 in Gelsenkirchen

Since 2004 Affiliated to Ecole supérieur de Biotechnologie Strasbourg (ESBS). Since 2004 Advisory board of the BMBF (German Federal Ministry of Science) program “Risk assessment in Plant Biotechnology”. 2004 - 2006 Guest editor Plant Biology. 2003 - 2006 Permanent member of the Habilitation-Board, Faculty of Biology, Freiburg University. Since 2003 Advisory Board of BioPro GmbH, a biotechnology enterprise of the federal state of Baden-Württemberg. Since 2002 Editorial Board of Plant Cell Reports. 2002-2005 Member of the FESPB (Federation of European Societies for Plant Biology) Grants and Awards Committee 2002 - 2005 Chairman of the advisory board at greenovation Biotech GmbH. 2002 - 2004 Managing Director/Co-Director of the Institute Biology II, Freiburg University. 2001 - 2002 Life Science co-ordinator of Freiburg University. Since 2001 Director Plant Biotechnology of the Centre for Applied Biosciences (ZAB) at Freiburg University. Since 2000 Advisory Board of InnoPlanta e.V. 1999 - 2002 Scientific co-ordinator of the BioRegio Freiburg. 09.09.1999 Co-founder of greenovation Plant Biotechnology GmbH. 1999 - 2005 Co-ordinator of the German National Science Foundation (DFG) priority program (SPP) “Molecular Analysis of Phytohormone Action”. Since 1999 Full Professor (C4), Chair Plant Biotechnology at Freiburg University. 1997-1999 Ranked 1st for an Associate Professorship in Norway (Oslo), ranked 3rd for a full professorship in Berlin (HU), ranked 2nd for a full professorship in Bremen, and ranked 1st for full professor-ships in Dresden (TU), Rostock and Freiburg. 1996-1999 Heisenberg-Fellow of the German National Science Foundation (DFG) at Freiburg University. 1994 Habilitation awarded in "General Botany". 1990-1996 Assistant Professor (C1) at Hamburg University, Department of Cell Biology. 1990 Ph.D. Degree (Dr. rer. nat.) at Hamburg University, Department of Genetics. Studies in Biology, Chemistry, Theory and Practice of Education at Gießen University and Hamburg University.

Hauptforschungsgebiete

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Wichtige Publikationen

1) Reski, R., W.O. Abel (1985): Induction of budding on chloronemata and caulonemata of the moss, Physcomitrella patens, using isopentenyladenine. Planta 165, 354-358. 2) Reski, R., W.O. Abel, D. Svensson (1986): Mutants of Physcomitrella patens sensitive to cytokinin. Mitt. Inst. Allg. Bot. Hamburg 21, 127-138. 3) Marienfeld, J.R., R. Reski, C. Friese, W.O. Abel (1989): Isolation of nuclear, chloroplast and mitochondrial DNA from the moss Physcomitrella patens. Plant Sci. 61, 235-244. 4) Ye, F., J. Gierlich, R. Reski, J. Marienfeld, W.O. Abel (1989): Isoenzyme analysis of cytokinin sensitive mutants of the moss Physcomitrella patens. Plant Sci. 64, 203-212. 5) Abel, W.O., W. Knebel, H.-U. Koop, J.R. Marienfeld, H. Quader, R. Reski, E. Schnepf, B. Spör-lein (1989): A cytokinin-sensitive mutant of the moss, Physcomitrella patens, defective in chloroplast division. Protoplasma 152, 1-13. 6) Reski, R., M. Wehe, B. Hadeler, J.R. Marienfeld, W.O. Abel (1991): Cytokinin and light quality interact at the molecular level in the chloroplast-mutant PC22 of the moss Physcomitrella. J. Plant Physiol. 138, 236-243. 7) Kasten, B., M. Wehe, R. Reski, W.O. Abel (1991): trnR-CCG is not unique to the plastid DNA of the liverwort Marchantia: gene identification from the moss Physcomitrella patens. Nucl. Acids Res. 19, 5074. 8) Marienfeld, J.R., R. Reski, W.O. Abel (1991): The first analysed archegoniate mitochondrial gene (cox3) exhibits extraordinary features. Curr. Genet. 20, 319-329. 9) Reski, R., W.O. Abel (1992): Analyzing cytokinins and plastid differentiation at the molecular level: Interference with genome/plastome-interaction, light quality, developmental state and endogenous oscillators. In: Physiology and biochemistry of cytokinins in plants. M. Kaminek, D.W.S. Mok, E. Zazimalova (eds.), pp 255-260. SPB Academic Publishing bv, The Hague, The Netherlands. 10) Reutter, K., M. Wehe, B. Kasten, W.O. Abel, R. Reski (1992): Cloning plastid DNA of the moss Physcomitrella patens. Mitt. Inst. Allg. Bot. Hamburg 24, 35-44. 11) Reski, R., M. Wehe, B. Kasten, K. Reutter, J.R. Marienfeld, W.O. Abel (1992): The molecular analysis of chloroplast division. Crypt. Bot. 3, 18-22. 12) Marienfeld, J.R., R. Reski, W.O. Abel (1992): Chondriom analysis of the moss Physcomitrella patens. Crypt. Bot. 3, 23-26. 13) Kasten, B., M. Wehe, S. Kruse, K. Reutter, W.O. Abel, R. Reski (1992): The plastome-encoded zfpA gene of a moss contains procaryotic as well as eucaryotic promoter consensus sequences and its RNA abundance is modulated by cytokinin. Curr. Genet. 22, 327-333. 14) Rother, S., B. Hadeler, J.M. Orsini, W.O. Abel, R. Reski (1994): Fate of a mutant macrochloroplast in somatic hybrids. J. Plant Physiol. 143, 72-77. 15) Reski, R., M. Faust, X.-H. Wang, M. Wehe, W.O. Abel (1994): Genome analysis of the moss Physcomitrella patens (Hedw.)B.S.G. Mol. Gen. Genet. 244, 352-359. 16) Reski, R. (1994): Plastid genes and chloroplast biogenesis. In: Cytokinins. Chemistry, Activity, and Function. D.W.S. Mok, M.C. Mok (eds.), pp 179-195. CRC Press, Boca Raton, Ann Arbor, London, Tokyo. 17) Neth, R., N. Drize, S. Gohla, R. Offergeld, R. Reski, S. Schrum (1995): Phytotherapeutische Forschung: Thuja occidentalis L. Z. Allg. Med. 71, 522-530. 18) Reski, R., K. Reutter, B. Kasten, M. Faust, S. Kruse, G. Gorr, R. Strepp, W.O. Abel (1995): Molecular analysis of chloroplast division. In: Current Issues in Plant Molecular and Cellular Biology. M. Terzi, R. Cella, A. Falavigna (eds.), pp 291-296. Kluwer Academic Publishers, Dordrecht, Boston, London. 19) Kruse, S., W. Martin, M. Wehe, R. Reski (1995): An open reading frame (ycf11) is evolutionarily conserved from cyanobacteria to the plastid DNAs of archegoniates and gymnosperms, is modified in the plastid DNAs of dicots, and is not plastome encoded in monocots. J. Plant Physiol. 146, 258-262. 20) Hadeler, B., S. Scholz, R. Reski (1995): Gelrite and agar differently influence cytokinin-sensitivity of a moss. J. Plant Physiol. 146, 369-371. 21) Kruse, S., S. Quast, A. Ipsen, K. Reutter, R. Reski (1995): Cytokinin affects stability of complex plastid transcripts in cytokinin-sensitive moss mutants. Plant Sci. 112, 187-196. 22) Neth, R., N. Drize, S. Gohla, R. Offergeld, R. Reski, S. Schrum (1995): Phytotherapeutische Forschung: Thuja occidentalis L. In: Jahrbuch Band 2. Karl und Veronica Carstens-Stiftung im Stifterverband für die Deutsche Wissenschaft. H. Albrecht, M. Frühwald (eds.), pp 240-251. Hippokrates Verlag, Stuttgart. 23) Reski, R., S. Schrum, R. Neth, S. Gohla (1995): Proteine enthaltende Komponente aus Thuja-Pflanzen sowie diese enthaltende Arzneimittel. Patent AZ 195 05 795. 24) Reutter, K., R. Reski (1996): Production of a heterologous protein in bioreactor cultures of fully differentiated moss plants. Pl. Tissue Cult. Biotech. 2, 142-147. 25) Kruse, S., R. Reski (1996): Expression of a plastome-encoded open reading frame with yet uncertain function (ycf11) in E. coli. Mitt. Inst. Allg. Bot. Hamburg 26, 131-144. 26) Tamura, M.N., A.E. Schwarzbach, S. Kruse, R. Reski (1997): Biosystematic studies on the genus Polygonatum (Convallariaceae) IV. Molecular phylogenetic analysis based on restriction site mapping of the chloroplast gene trnK. Feddes Repert. 108, 159-168. 27) Kasten, B., F. Buck, J. Nuske, R. Reski (1997): Cytokinin affects nuclear- and plastome-encoded energy-converting plastid enzymes. Planta 201, 261-272. 28) Kasten, B., R. Reski (1997): -lactam antibiotics inhibit chloroplast division in a moss (Physcomitrella patens) but not in tomato (Lycopersicon esculentum). J. Plant Physiol. 150, 137-140. 29) Ye, F., W.O. Abel, R. Reski (1998): Isolation of plant mitochondrial RNA from green leaves. In: Methods in Molecular Biology, Vol. 86: RNA isolation and characterisation protocols. R. Rapley, D.L. Manning (eds.), pp. 33-38. Humana Press Inc., Totowa NY. 30) Reski, R. (1998): Development, genetics and molecular biology of mosses. Bot. Acta 111, 1-15. 31) v. Schwartzenberg, K., S. Kruse, R. Reski, B. Moffatt, M. Laloue (1998): Cloning and characterization of an adenosine kinase from Physcomitrella involved in cytokinin metabolism. Plant J. 13, 249-257. 32) Reski, R., S. Reynolds, M. Wehe, T. Kleber-Janke, S. Kruse (1998): Moss (Physcomitrella patens) expressed sequence tags include several sequences which are novel for plants. Bot. Acta 111, 145-151. 33) Strepp, R., S. Scholz, S. Kruse, V. Speth, R. Reski (1998): Plant nuclear gene knockout reveals a role in plastid division for the homolog of the bacterial cell division protein FtsZ, an ancestral tubulin. Proc. Natl. Acad. Sci. USA 95, 4368-4373. 34) Reski, R. (1998): Physcomitrella and Arabidopsis: the David and Goliath of reverse genetics. Trends Plant Sci. 3, 209-210. 35) Girke, T., H. Schmidt, U. Zähringer, R. Reski, E. Heinz (1998): Identification of a novel 6-acyl-group desaturase by targeted gene disruption in Physcomitrella patens. Plant J. 15, 39-48. 36) Reutter, K., R. Atzorn, B. Hadeler, T. Schmülling, R. Reski (1998): Expression of the bacterial ipt gene in Physcomitrella rescues mutations in budding and in plastid division. Planta 206, 196-203. 37) Reski, R. (1999): Molecular genetics of Physcomitrella. Planta 208, 301-309. 38) Ye, F., R. Reski (1999): An improved method to isolate mitochondrial RNA from green plant tissue. In: The Nucleic Acid Protocols Handbook. R. Rapley (ed.). Humana Press, Totowa NY. 39) Schulz, P., R. Reski, R. Maldiney, M. Laloue, K. v. Schwartzenberg (2000): Kinetics of cytokinin production and bud formation in Physcomitrella: Analysis of a wild type, a developmental mutant and two of its ipt transgenics. J. Plant Physiol. 156, 768-774. 40) Kiessling, J., S. Kruse, S.A. Rensing, K. Harter, E.L. Decker, R. Reski (2000): Visualization of a cytoskeleton-like FtsZ network in chloroplasts. J. Cell Biol. 151, 945-950. 41) Hohe, A., G. Schween, R. Reski (2001): Establishment of a semicontinuous bioreactor culture of Physcomitrella patens for mass production of protoplasts. Acta Horticulturae 560, 425-428. 42) Reski, R., G. Gorr (2001): Method for production of proteinaceous substances. Patent: WO 01/25456. 43) Reindl, A., R. Reski, J. Lerchl, B. Grimm, A. Al-Awadi (2001): Plant s-adenosylmethionin:mg-protoporphyrin-IX-o-methyltransferase, plants with variable chlorophyll contents and/or herbicide tolerance, and method for the production thereof. Patent: WO 01/09355-A. 44) Lerchl, J., A. Renz, T. Ehrhardt, A. Reindl, P. Cirpus, F. Bischoff, M. Frank, A. Freund, E. Duwenig, R.M. Schmidt, R. Reski (2001): Moss genes from Physcomitrella patens encoding proteins involved in the synthesis of polyunsaturated fatty acids and lipids. Patent: WO 01/38484-A. 45) Rak, B., R. Reski, S. Zimmermann, M.-C. Guitton, E. Duwenig, A. Freund (2001): Method for the mutagenesis of nucleotide sequences from plants, algae and fungi. Patent WO 01/38509 A1 46) Lerchl, J., A. Renz, T. Ehrhardt, A. Reindl, P. Cirpus, F. Bischoff, M. Frank, A. Freund, E. Duwenig, R.M. Schmidt, R. Reski (2001): Moss genes from Physcomitrella patens encoding proteins involved in the synthesis of polyunsaturated fatty acids and lipids. Patent: WO 01/38541-A. 47) Lerchl, J., A. Renz, T. Ehrhardt, A. Reindl, P. Cirpus, F. Bischoff, M. Frank, A. Freund, E. Duwenig, R.M. Schmidt, R. Reski (2001): Moss genes from Physcomitrella patens encoding proteins involved in the synthesis of carbohydrates. Patent: WO 01/44476-A. 48) Bhatla, S.C., J. Kiessling, R. Reski (2002): Observation of polarity induction by cytochemical localization of phenylalkylamine-binding receptors in regenerating protoplasts of the moss Physcomitrella patens. Protoplasma 219, 99-105. 49) Egener, T., J. Granado, M.-C. Guitton, A. Hohe, H. Holtorf, J.M. Lucht, S. Rensing, K. Schlink, J. Schulte, G. Schween, S. Zimmermann, E. Duwenig, B. Rak, R. Reski (2002): High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library. BMC Plant Biology 2, 6. 50) Hohe, A., E.L. Decker, G. Gorr, G. Schween, R. Reski (2002): Tight control of growth and cell differentiation in photoautotrophically growing moss (Physcomitrella patens) bioreactor cultures. Plant Cell Rep. 20, 1135-1140. 51) Hohe, A., R. Reski (2002): Optimisation of a bioreactor culture of the moss Physcomitrella patens for mass production of protoplasts. Plant Sci. 163, 69-74. 52) Hohe, A., S.A. Rensing, M. Mildner, D. Lang, R. Reski (2002): Day length and temperature strongly influence sexual reproduction and expression of a novel MADS-box gene in the moss Physcomitrella patens. Plant Biol. 4, 595-602. 53) Holtorf, H., A. Hohe, H.-L. Wang, M. Jugold, T. Rausch, E. Duwenig, R. Reski (2002): Promoter subfragments of the sugar beet V-type H+-ATPase subunit c isoform drive the expression of transgenes in the moss Physcomitrella patens. Plant Cell Rep. 21, 341-346. 54) Holtorf, H., M.-C. Guitton, R. Reski (2002): Plant functional genomics. Naturwissenschaften 89, 235-249. 55) Koprivova, A., A.J. Meyer, G. Schween, C. Herschbach, R. Reski, S. Kopriva (2002): Functional knockout of the adenosine 5´-phosphosulfate reductase gene in Physcomitrella patens revives an old route of sulfate assimilation. J. Biol. Chem. 277, 32195-32201. 56) Rensing, S.A., S. Rombauts, A. Hohe, D. Lang, E. Duwenig, P. Rouze, Y. Van de Peer, R. Reski (2002): The transcriptome of the moss Physcomitrella patens: comparative analysis reveals a rich source of new genes. http://www.plant-biotech.net/Rensing_et_al_transcriptome2002.pdf. 57) Reski, R. (2002): Rings and networks: the amazing complexity of FtsZ in chloroplasts. Trends Plant Sci. 7, 103-105. 58) Richter, U., J. Kiessling, B. Hedtke, E. Decker, R. Reski, T. Börner, A. Weihe (2002): Two RpoT genes of Physcomitrella patens encode phage-type RNA polymerases with dual targeting to mitochondria and plastids. Gene 290, 95-105. 59) Schipper, O., D. Schaefer, R. Reski, A. Fleming (2002): Expansins in the bryophyte Physcomitrella patens. Plant Mol. Biol. 50, 789-802. 60) Schween, G., S. Fleig, R. Reski (2002): High-throughput-PCR screen of 15,000 transgenic Physcomitrella plants. Plant Mol. Biol. Rep. 20, 43-47. 61) Zank, T.K., U. Zähringer, C. Beckmann, G. Pohnert, W. Boland, H. Holtorf, R. Reski, J. Lerchl, E. Heinz (2002): Cloning and functional characterisation of an enzyme involved in the elongation of 6-polyunsaturated fatty acids from the moss Physcomitrella patens. Plant J. 31, 255-268. 62) Rensing, S.A., S. Rombauts, Y. Van de Peer, R. Reski (2002): Moss transcriptome and beyond. Trends Plant Sci. 7, 535-538. 63) Schlink, K, R. Reski (2002): Preparing high-quality DNA from moss (Physcomitrella patens). Plant Mol. Biol. Rep. 20, 423a-423f. 64) Sperling, P., T. Egener, J. Lucht, R. Reski, P. Cirpus, E. Heinz (2002): Identification of a 5-fatty acid desaturase from Physcomitrella patens. In: Advanced Researches on Plant Lipids. N. Murata, M. Yamada, I. Nishida, J. Sekiya, H. Wada (eds.), pp. 113-116. Kluwer Academic Publishers, Dordrecht. 65) Reski, R. (2003): Physcomitrella patens as a novel tool for plant functional genomics. In: Plant biotechnology 2002 and beyond. I.K. Vasil (ed.) Kluwer Acad. Publ., 205-209. 66) Schween, G., A. Hohe, A. Koprivova, R. Reski (2003): Effects of nutrients, cell density and culture techniques on protoplast regeneration and early protonema development in a moss, Physcomitrella patens. J. Plant Physiol. 160, 209-212. 67) Schween, G., G. Gorr, A. Hohe, R. Reski (2003): Unique tissue-specific cell cycle in Physcomitrella. Plant Biol. 5, 50-58. 68) Decker, E.L., G. Gorr, R. Reski (2003): Moss – An innovative tool for protein production. BioForum Europe 7, 96-97. 69) Hohe, A., R. Reski (2003): A tool for understanding homologous recombination in plants. Plant Cell Rep. 21, 1135-1142. 70) Bierfreund, N., R. Reski, E.L. Decker (2003): Use of an inducible reporter gene system for the analysis of auxin distribution in the moss Physcomitrella patens. Plant Cell Rep. 21, 1143-1152. 71) Lorenz, S., S. Tintelnot, R. Reski, E.L. Decker (2003): Cyclin D-knockout uncouples developmental progression from sugar availability. Plant Mol. Biol. 53, 227-236. 72) Rensing, S.A., D. Lang D., R. Reski (2003): In silico prediction of UTR repeats using clustered EST data. In: Proceedings of the German Conference on Bioinformatics 2003. H.-W. Mewes, V. Heun, D. Frishman, S. Kramer (eds.), pp 117-122, Belleville Verlag Michael Farin, Munich, Germany 73) Koprivova, A., F. Altmann, G. Gorr, S. Kopriva, R. Reski, E.L. Decker (2003): N-glycosylation in the moss Physcomitrella patens is organized similarly to higher plants. Plant Biol. 5, 582-591. 74) Hohe, A., T. Egener, J.M. Lucht, H. Holtorf, C. Reinhard, R. Reski (2004): An improved and highly standardised transformation procedure allows efficient production of single and multiple targeted gene knockouts in a moss, Physcomitrella patens. Curr. Genet. 44, 339-347. 75) Rensing, S.A., J. Kiessling, R. Reski, E.L. Decker (2004): Diversification of ftsZ during early land plant evolution. J. Mol. Evol. 58,154-162. 76) Decker, E.L., R. Reski (2004): The moss bioreactor. Current Opinion Plant Biology 7, 166-170. 77) Schulte, S., R. Reski (2004): High-throughput cryopreservation of 140000 Physcomitrella patens mutants. Plant Biol. 6, 119-127. 78) Heintz, D., V. Wurtz, A. High, A. Van Dorsselaer, R. Reski, E. Sarnighausen (2004): An efficient protocol for the identification of protein phosphorylation in a seedless plant, sensitive enough to detect members of signalling cascades. Electrophoresis 25, 1149-1159. 79) Reski, R., D.J. Cove (2004): Quick guide: Physcomitrella patens. Current Biology 14, R261-R262. 80) Kroemer, K., R. Reski, W. Frank (2004): Abiotic stress response in the moss Physcomitrella patens: evidence for an evolutionary alteration in signaling pathways in land plants. Plant Cell Rep. 22, 864-870. 81) Schaaf, A., R. Reski, E.L. Decker (2004): A novel aspartic proteinase is targeted to the secretory pathway and to the vacuole in the moss, Physcomitrella patens. Eur. J. Cell Biol. 83, 145-152. 82) Holtorf, H., W. Frank, R. Reski (2004): Applied genomics in Physcomitrella. In: New frontiers in bryology: Physiology, molecular biology and applied genomics. A.J. Wood, M.J. Oliver, D.J. Cove (eds.), pp 51-70. Kluwer Academic Press, The Netherlands. 83) Bierfreund, N.M., S. Tintelnot, R. Reski, E.L. Decker (2004): Loss of GH3-function does not affect phytochrome-mediated development in a moss, Physcomitrella patens. J. Plant Physiol. 161, 823-835. 84) Sarnighausen, E., V. Wurtz, D. Heintz, A. van Dorsselaer, R. Reski (2004): Mapping of the Physcomitrella patens proteome. Phytochemistry 65, 1589-1607. 85) Wood, A.J., R. Reski, W. Frank (2004): Isolation and characterization of ALDH11A5, a novel non-phosphorylating GAPDH cDNA from Physcomitrella patens. The Bryologist 107, 385-387. 86) Horstmann, V., C.M. Hüther, W. Jost, R. Reski, E.L. Decker (2004): Quantitative promoter analysis in Physcomitrella patens: a set of plant vectors activating gene expression within three orders of magnitude. BMC Biotechnology 4, 13. 87) Jost, W., A. Baur, P. Nick, R. Reski, G. Gorr (2004): A large plant beta-tubulin family with minimal C-terminal variation but differences in expression. Gene 340, 151-160. 88) Koprivova, A., C. Stemmer, F. Altmann, A. Hoffmann, S. Kopriva, G. Gorr, R. Reski, E.L. Decker (2004): Targeted knockouts of Physcomitrella lacking plant-specific immunogenic N-glycans. Plant Biotech. J. 2, 517-523. 89) Hohe, A., M. Seyring, K.-T. Hänsch, E. Sarnighausen, S. Rensing, R. Reski (2004): Embryonen im Bioreaktor – Neue Wege bei der Vermehrung von Alpenveilchen. BMVEL Forschungsreport 1/2004, 25-27. 90) Kiessling, J., A. Martin, L. Gremillon, S.A. Rensing, P. Nick, E. Sarnighausen, E.L. Decker, R. Reski (2004): Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm. EMBO Rep. 5, 889-894. 91) Frank, W., D. Ratnadewi, R. Reski (2005): Physcomitrella patens is highly tolerant against drought, salt and osmotic stress. Planta 220, 384-394. 92) Frank, W., H. Holtorf, R. Reski (2005): Functional genomics in Physcomitrella. In: Plant functional genomics. D. Leister (ed.), pp. 203-234. The Harworth Press, Binghamton, New York, USA. 93) Jost, W., S. Link, V. Horstmann, E.L. Decker, R. Reski, G. Gorr (2004): Isolation and characterisation of three moss derived beta-tubulin promoters suitable for recombinant expression. Curr. Genet. 47, 111-120. 94) Hohe, A., R. Reski (2005): From axenic spore germination to molecular farming: one century of bryophyte in vitro culture. Plant Cell Rep. 23, 513-521. 95) Schween, G., A. Hohe, J. Schulte, R. Reski (2005): Effect of ploidy level on growth, differentiation and phenotype in Physcomitrella patens. The Bryologist 108, 27-35. 96) Alawady, A., R. Reski, E. Yaronskaya, B. Grimm (2005): Cloning and expression of the tobacco CHLM sequence encoding Mg protoporphyrin IX methyltransfe-rase and its interaction with Mg chelatase. Plant Mol. Biol. 57, 679-691. 97) Baur, A., R. Reski, G. Gorr (2005): Enhanced recovery of a secreted recombinant human growth factor using stabilizing additives and by co-expression of human serum albumin in the moss Physcomitrella patens. Plant Biotech. J. 3, 331-340. 98) Hohe, A., R. Reski (2005): Control of growth and differentiation of bioreactor cultures of Physcomitrella by environmental parameters. Plant Cell, Tissue and Organ Culture 81, 307-311. 99) Rensing, S.A., D. Fritzowsky, D. Lang, R. Reski (2005): Protein encoding genes in an ancient plant: analysis of codon usage, retained genes and splice sites in a moss, Physcomitrella patens. BMC Genomics 6, 43. 100) Reski, R., W. Frank (2005): Moss (Physcomitrella patens) functional genomics – Gene discovery and tool development with implications for crop plants and human health. Briefings in Functional Genomics & Proteomics 4, 48-57. 101) Reski, R. (2005): Do we need another model plant? Plant Biol. 7, 219. 102) Frank, W., E.L. Decker, R. Reski (2005): Molecular tools to study Physcomitrella patens. Plant Biol. 7, 220-227. 103) Schween, G., T. Egener, D. Fritzkowsky, J. Granado, M.-C. Guitton, N. Hartmann, A. Hohe, H. Holtorf, D. Lang, J.M. Lucht, C. Reinhard, S.A. Rensing, K. Schlink, J. Schulte, R. Reski (2005): Large-scale analysis of 73,329 Physcomitrella plants transformed with different gene disruption libraries: Production parameters and mutant phenotypes. Plant Biol. 7, 228-237. 104) Lang, D., J. Eisinger, R. Reski, S.A. Rensing (2005): Representation and high-quality annotation of the Physcomitrella patens transcriptome demonstrates a high proportion of proteins involved in metabolism in mosses. Plant Biol. 7, 238-250. 105) Hüther, C.M., O. Lienhart, A. Baur, C. Stemmer, G. Gorr, R. Reski, E.L. Decker (2005): Glyco-engineering of moss lacking plant-specific sugar residues. Plant Biol. 7, 292-299. 106) Baur, A., F. Kaufmann, H. Rolli, A. Weise, R. Luethje, B. Berg, M. Braun, W. Baeumer, M. Kietzmann, R. Reski, G. Gorr (2005): A fast and flexible PEG-mediated transient expression system in plants for high level expression of secreted recombinant proteins. J. Biotechnology 119, 332-342. 107) Rensing, S.A., D. Lang, E. Schumann, R. Reski, A. Hohe (2005): EST sequencing from embryogenic Cyclamen persicum cell cultures identifies a high proportion of transcripts homologous to plant genes involved in somatic embryogenesis. J. Plant Growth Regulation 24, 102-115. 108) Wischgoll, S., D. Heintz, F. Peters, A. Erxleben, E. Sarnighausen, R. Reski, A. Van Dorsselaer, M. Boll (2005): Gene clusters involved in anaerobic benzoate degradation of Geobacter metallireducens. Molecular Microbiology 58, 1238-1252. 109) Schaaf, A., S. Tintelnot, A. Baur, R. Reski, G. Gorr, E.L. Decker (2005): Use of endogenous signal sequences for transient production and efficient secretion by moss (Physcomitrella patens) cells. BMC Biotechnology 5: 30.

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