Dr. Laura Soledad Mazzaferro

geb. am 13.10.1984 in General Pico

2012-2014. Postdoc, founded by Alexander von Humboldt Foundation. “Filamentous fungi P450s toolbox for the synthesis of fine chemicals”. University of Freiburg, Germany. Supervisor: Prof. Dr. Michael Müller. 2007-2011. Doctoral Degree in Biology. National University of Comahue, Argentina. Topic of the thesis work: “α-Rhamnosyl-β-glucosidase”. Supervisor: Prof. Dr. Javier D. Breccia. Final grade: Sobresaliente (10). 2002-2007. Degree in Chemistry. National University of La Pampa (UNLPam), Argentina. Final grade: 9.48.

Fakultät für Chemie und Pharmazie

Hauptforschungsgebiete

Biocatalysis

Wichtige Publikationen

Weiz G, Breccia JD, Mazzaferro LS. 2017. Screening and quantification of the enzymatic deglycosylation of the plant flavonoid rutin by UV–visible spectrometry. Food Chem 229:44-49. Neher BD, Mazzaferro LS, Oyhenart J, Kotík M, Halada P, Křen V, Breccia JD. 2016. Bacteria as source of diglycosidase activity: Actinoplanes missouriensis produces 6-O-α-l-rhamnosyl-β-d-glucosidase active on flavonoids. Appl Microbiol Biotechnol 100:3061-3070. Mazzaferro LS, Hüttel W, Fries A, Müller M. 2015. Cytochrome P450-catalyzed regio- and stereoselective phenol coupling of fungal natural products. J Am Chem Soc 137:12289-12295. Mazzaferro LS, Breccia JD. 2012. Quantification of hesperidin in citrus-based foods using a fungal diglycosidase. Food Chem 134:2338-2344 Mazzaferro LS, Piñuel L, Erra-Balsells R, Giudicessi SL, Breccia JD. 2012. Transglycosylation specificity of Acremonium sp. α-rhamnosyl-β-glucosidase and its application to the synthesis of the new fluorogenic substrate 4-methylumbelliferyl-rutinoside. Carbohydr Res 347:69-75. Mazzaferro LS & Breccia JD. 2011. Functional and biotechnological insights into diglycosidases. Biocatal Biotrans 29:103-112. Mazzaferro L, Breccia JD, Andersson MM, Hitzmann B & Hatti-Kaul R. 2010. Polyethyleneimine-protein interactions and implications on protein stability. Int J Biol Macromol 47:15-20. Mazzaferro L, Piñuel L., Minig M & Breccia JD. 2010. Extracellular monoenzyme deglycosylation system of 7-O-linked flavonoid β-rutinosides and its disaccharide transglycosylation activity from Stilbella fimetaria. Arch Microbiol 192(5):383-393. Erratum: Arch Microbiol (2011) 193:461

Kontaktaufnahme

Tel: +49 (0) 761-203-6339
Fax: +49 (0) 761-201-6351
Email: Laura.Soledad.Mazzaferro@pharmazie.uni-freiburg.de

Adresse / Postanschrift:
Institut für Pharmazeutische Wissenschaften
Arbeitskreis Prof. Dr. Michael Müller
Albertstraße 25 (Otto-Krayer-Haus)
79104 Freiburg i. Br.

Telefon: (+49) 0761/203-6320
Email: michael.mueller@pharmazie.uni-freiburg.de
http://www.pharmazie.uni-freiburg.de/chemie/