PD Dr. Stephan Seiler

geb. am 25.05.1967 in München

1989 – 1995 Studies of Biology at the Ludwig-Maximilians-University Munich, Germany 1995 – 1999 PhD Thesis at the University of Edmonton, Alberta, Canada and the LMU Munich, Germany 2000 – 2001 EMBO post-doctoral Fellow at the University of Missouri, Kansas City, USA 2002 Scientific Assistant at the Ludwig-Maximilians-University Munich, Germany 2003 – 2009 Principal Investigator at the DFG Research Centre for Molecular Physiology of the Brain, Georg-August University of Göttingen, Germany 2004 – 1012 Group Leader at the Centre for Molecular Biosciences, Georg-August University of Göttingen, Germany 2013 – today Heisenberg Fellow at the Institute for Biology II, Molecular Plant Physiology, Albert-Ludwigs University Freiburg, Germany

Fakultät für Biologie

Hauptforschungsgebiete

Fungal Genetics and Biology

Wichtige Publikationen

Dettmann, A., Illgen, J, März, S., Schürg, T., Fleissner, A., and Seiler, S.* (2012). The NDR kinase scaffold HYM1/MO25 is essential for MAK2 MAP kinase signaling in Neurospora crassa. PLOS Genetics, 8, e1002950. März, S., Dettmann, A., and Seiler, S.* (2012). Hydrophobic motif phosphorylation coordinates activity and polar localization of the Neurospora crassa nuclear Dbf2-related kinase COT1. Mol. Cell. Biol., 32, 2083-2098. Richthammer, C., Enseleit, M., Sanchez-Leon, E., März, S., Heilig, Y., Riquelme, M., and Seiler, S.* (2012). RHO1 and RHO2 share partially overlapping functions in the regulation of cell wall integrity and hyphal polarity in Neurospora crassa. Mol. Microbiol. 85, 716-733. März, S., Funakoshi, Y., Negishi, Y., Suzuki, T., and Seiler, S.* (2010). The Neurospora peptide:N-glycanase ortholog PNG1 is essential for cell polarity despite its lack of enzymatic activity. J. Biol. Chem. 285, 2326-2332. Justa-Schuch, D., Heilig, Y., Richthammer, C., and Seiler, S.* (2010). Septum formation is regulated by the RHO4-specific exchange factors BUD3 and RGF3 and by the landmark protein BUD4 in Neurospora crassa. Mol. Microbiol. 76, 220-235. März, S., Dettmann, A., Ziv, C., Liu, Y., Valerius, O., Yarden, O., and Seiler, S.* (2009). Two NDR kinase-MOB complexes function as distinct modules during septum formation and tip extension in Neurospora crassa. Mol. Microbiol. 74, 707-723. Vogt, N., and Seiler, S.* (2008). LRG1 is a RHO1 specific GTPase activating protein in Neurospora crassa that regulates polar tip extension in parallel with the NDR kinase COT1. Mol. Biol. Cell, 19, 4554-4569. Seiler, S.*, Vogt, N., Ziv, C., Gorovits, R., and Yarden, O. (2006). The STE20/germinal center kinase POD6 interacts with the NDR kinase COT1 and is involved in polar tip extension in a motor protein-dependent manner in Neurospora crassa. Mol. Biol. Cell, 17, 4080-4092. Seiler, S.* and Plamann, M. (2003). The genetic basis of cellular morphogenesis in the filamentous fungus Neurospora crassa. Mol. Biol. Cell, 14, 4352-4364. Seiler, S., Kirchner, J., Horn, C., Kallipolitou, A., Woehlke, G., and Schliwa, M. (2000). Cargo binding and regulatory sites in the tail of fungal konventional kinesin. Nature Cell Biol. 2, 333-338.

Kontaktaufnahme

Tel: 0761-203-2669
Email: Stephan.Seiler@biologie.uni-freiburg.de

Adresse / Postanschrift:
Institut für Biologie II
Botanik
Schaenzlestr. 1
79104 Freiburg i. Br.

Telefon: 203-2960
Fax: 203-2612
http://www.biologie.uni-freiburg.de/forschung/botanik.php