Dr. rer. nat Daria Onichtchouk

geb. am 18.05.1965 in Moskau/Russland 1982-1989 Study of Biology at the Moscow Lomonossow University 1993-1995 Scientist in the Lab. Mediators of Immunity. Haematological centre, Russia, head- Dr. A. B. Sudarikov 1995-1999 PhD Student in German Cancer Research Center (Dr. rer. nat., magna cum laude) 1999-2001 Postdoc at the MPI Biophysical Chemistry, Göttingen 2001-2006 Senior Scientist, DeveloGen AG Göttingen Since 2006 Lecturer/Akademische Rätin A13, University of Freiburg Fakultät für Biologie

Hauptforschungsgebiete

Entwicklungsbiologie, Systembiologie

Wichtige Publikationen

1. Onichtchouk Daria. Pou5f1 – stem cell transcription factor in embryo (review) Genesis. 2011 Sep 12. 2. Belting HG, Wendik B, Lunde K, Leichsenring M, Mössner R, Driever W, Onichtchouk D. Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression. Dev Biol. 2011 May 20. 3. Onichtchouk D, Geier F, Polok B, Messerschmidt DM, Moessner R, Wendik B, Song S, Taylor V, Timmer J, Driever W. Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. Mol Syst Biol. 2010;6:354. Epub 2010 Mar 9. PubMed PMID: 20212526; PubMed Central PMCID: PMC2858445. 4. Phylogenetically conserved POU factor-dependent regulation of Sox2 by enhancer N-2 at epiblast to anterior neural plate stages of embryo. Makiko Iwafuchi-Doi, Yuzo Yoshida, Daria Onichtchouk, Manuel Leichsenring, Wolfgang Driever,Tatsuya Takemoto, Masanori Uchikawa, Yusuke Kamachi, Hisato Kondoh Dev Biol. 2010 Dec 23. 5. Controlling the development of stem cells (regulatory networks in the embryo) Wolfgang Driever and Daria Onichtchouk, (german version published at 01.Juni 2010, www.systembiologie.de; international print issue: 01. October 2010) 6: Majoul IV, Onichtchouk D, Butkevich E, Wenzel D, Chailakhyan LM, Duden R. Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway. Histochem Cell Biol. 2009 Sep;132(3):263-80. Epub 2009 Jul 22. PubMed PMID: 19626334; PubMed Central PMCID: PMC2756399. 7: Bulina ME, Lukyanov KA, Britanova OV, Onichtchouk D, Lukyanov S, Chudakov DM. Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed. Nat Protoc. 2006;1(2):947-53. PubMed PMID: 17406328. 8: Mussmann R, Geese M, Harder F, Kegel S, Andag U, Lomow A, Burk U, Onichtchouk D, Dohrmann C, Austen M. Inhibition of GSK3 promotes replication and survival of pancreatic beta cells. J Biol Chem. 2007 Apr 20;282(16):12030-7. Epub 2007 Jan 22. PubMed PMID: 17242403. 9: Onichtchouk D, Aduroja K, Belting HG, Gn√ºgge L, Driever W. Transgene driving GFP expression from the promoter of the zona pellucida gene zpc is expressed in oocytes and provides an early marker for gonad differentiation in zebrafish. Dev Dyn. 2003 Nov;228(3):393-404. PubMed PMID: 14579378. 10: Niehrs C, Dosch R, Onichtchouk D. Embryonic patterning of Xenopus mesoderm by Bmp-4. Ernst Schering Res Found Workshop. 2000;(29):165-90. Review. PubMed PMID: 10943310. 11: Onichtchouk D, Chen YG, Dosch R, Gawantka V, Delius H, Massagu√© J, Niehrs C. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature. 1999 Sep 30;401(6752):480-5. PubMed PMID: 10519551. 12: Onichtchouk D, Glinka A, Niehrs C. Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm. Development. 1998 Apr;125(8):1447-56. PubMed PMID: 9502725. 13: Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R, Niehrs C, Cho KW. Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads. Development. 1997 Nov;124(22):4467-80. PubMed PMID: 9409665. 14: Glinka A, Wu W, Onichtchouk D, Blumenstock C, Niehrs C. Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus. Nature. 1997 Oct 2;389(6650):517-9. PubMed PMID: 9333244. 15: Onichtchouk D, Gawantka V, Dosch R, Delius H, Hirschfeld K, Blumenstock C, Niehrs C. The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling dorsoventral patterning of Xenopus mesoderm. Development. 1996 Oct;122(10):3045-53. Erratum in: Development 1997 Jan;124(1):precedi. PubMed PMID: 8898218.

Kontaktaufnahme

Tel: 0761/203-2595
Fax: 0761/203-2597
Email: daria.onichtchouk@biologie.uni-freiburg.de

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