PD Dr. Gerald Radziwill

geb. am 14.08.1960 in Freiburg i.Br.

Born 14.08.1960 in Freiburg i.Br., Gymnasium (high school) in Karlsruhe; 1980-1985 Study of Biology at the University of Heidelberg; 1985-1989 PhD (Dr.rer.nat.) at the ZMBH/University of Heidelberg (laboratory of Heinz Schaller; 1989-1993 postdoc at the MPI for Molecular Genetics in Berlin (laboratoryof Karin Moelling); 1994-1998 research assistent at the Institute of Medical Virology (University of Zurich); 1999-2009 project leader/senior research assistent (Oberassistent)at the Institute of Medical Virology (University of Zurich); 2008 Habilitation; since 05/2009 deputy professor of Biochemistry at the University of Freiburg, Faculty of Biology

Fakultät für Biologie

Hauptforschungsgebiete

signal transduction; tumor biology

Wichtige Publikationen

Fritz R.D. and Radziwill G. CNK1 and other scaffolds for Akt/FoxO signaling. Biochim Biophys Acta – Molecular Cellular Research 1813, 1971-1977 (2011) Fritz R.D., Varga Z., and Radziwill G. CNK1 is a novel Akt interaction partner that promotes cell proliferation through the Akt/FoxO signalling axis. Oncogene 29, 3575-3582 (2010) Fritz R. D. and Radziwill G. CNK1 promotes invasion of cancer cells through NF-kappaB-dependent signalling. Mol Cancer Res 8, 395-406 (2010) Usluoglu N., Pavlovic J., Moelling K., and Radziwill G. RIP2 mediates LPS-induced p38 and IkBk signalling including IL-12 p40 expression in human monocyte-derived dendritic cells. Eur. J. Immunol. 37, 2317-2325 (2007). Radziwill G∆., Weiss A., Heinrich J., Baumgartner M., Boisguerin P., Owada K., and Moelling K∆. Regulation of c-Src by binding to the PDZ domain of AF-6. EMBO J. 26, 2633–2644 (2007). ∆ corresponding authors Ziogas A., Moelling K., and Radziwill G. The scaffold protein CNK connects Raf-1 and Src signalling. J. Biol. Chem. 280, 24205-24211 (2005). Radziwill G., Erdmann R., Margelisch U., Moelling K. Bcr is a PDZ domain binding kinase that phosphorylates AF-6 and downregulates Ras/Raf signaling. Mol Cell Biol. 23, 4663-46672 (2003). Radziwill G., Tucker W., and Schaller H. Mutational analysis of the hepatitis B virus P-gene product: domain structure and RNase H activity. J. Virol. 64, 613-620 (1990).

Kontaktaufnahme

Tel: +49 761 203 2635
Fax: + 49 761 203 2601
Email: gerald.radziwill@bioss.uni-freiburg.de

Adresse / Postanschrift:
Biologie II
Synthetische Biologie / bioss
Schänzlestr. 18
79104 Freiburg

Telefon: +49(0)761 203-97654
Fax: +49(0)761 203-97660
Email: wilfried.weber@biologie.uni-freiburg.de