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 Forschungsbericht für das Jahr 2018

Institut für Biologie 3

Professur für Optophysiologie und Neurophysiologie

Albertstr. 23
79104 Freiburg
Tel: 5073
Email Sabine.Weber@biologie.uni-freiburg.de

Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Ilka Diester, Leitung (m/w)
  • Priv.-Doz. Dr. Philippe Coulon, Postdoc (m/w)
  • Dr. Brice de la Crompe de la Boissiere, Postdoc (m/w)
  • Dr. David Eriksson
  • Dr. Stefanie Hardung, Postdoc (m/w)
  • Dr. Sun Zong-Peng, Postdoc (m/w)
  • Jan Deubner, Wissenschaftlicher Mitarbeiter (m/w)
  • Zoe Jäckle, Doktorand (m/w)
  • Golan Karvat, Doktorand (m/w)
  • Artur Schneider, Doktorand (m/w)
  • Mansour Alyahyay, Doktorand (m/w)
  • Christine Zeschnigk, Technischer Mitarbeiter (m/w)
Einträge in der Rubrik "Who is Who"


  • Deep-Decode In order to build closed-loop devices that read the status of a certain brain area to steer a prosthetic limb and provide feedback information from a sensor via stimulation, it is necessary to learn about the coding mechanism in the involved brain areas. To this end, we develop ways to predict body motion from neural recordings (decoding) and vice-versa (encoding) using latest deep learning methods. (Collaboration with Professor Thomas Brox, Computer Vision Laboratory, University of Freiburg, Germany and Dr Patrick Ruther, Department of Microsystems Engineering – IMTEK, University of Freiburg, Germany)
  • Deep-Tracking We apply artificial neural networks (Deep Learning) for automatic object recognition and precise behavior tracking. (Collaboration with Professor Thomas Brox, Computer Vision Laboratory, University of Freiburg, Germany)
  • Neuro-Stim Causal interference with the brain is one of the currently leading themes in basic and clinical neuroscience. For this, brain stimulation paradigms have been proven to be extremely valuable tools. We aim to develop paradigms which allow powerful interactions with the brain with clinical relevance. (Collaboration with Professor Carsten Mehring, Institute of Biology III & Bernstein Center Freiburg, University of Freiburg, Germany and Professor Thomas Stieglitz IMTEK - Institut für Mikrosystemtechnik, University of Freiburg, Germany)
  • Opto-Computation How does the local organization of motor cortex look like in terms of encoding of different movement types? We address this question with a combination of experimental and computational tools.
  • Opto-Control What makes us start or stop a movement? Prefrontal areas are executively involved in this process. In this project, we investigate the impact of prefrontal input on motor cortex activity
  • Opto-Motor What drives a movement locally? The role of different cell types are investigated.
  • Opto-Pathway How are different outputs of motor cortex organized and coordinated?

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • O'Shea DJ, Kalanithi P, Ferenczi EA, Hsueh B, Chandrasekaran C, Goo W, Diester I, Ramakrishnan C, Kaufman MT, Ryu SI, Yeom KW, Deisseroth K, Shenoy KV: Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys Sci Rep-uk, 2018; 8 (1): 6775. : https://www.nature.com/articles/s41598-018-24362-7

Besondere wissenschaftliche Aktivitäten