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 Forschungsbericht für das Jahr 2017

Department für Radiologische Diagnostik und Therapie

Klinik für Strahlenheilkunde

Robert Koch Str. 3
79106 Freiburg
Tel: 0049-761-270-9461 Fax: 0049-761-270-9472
Email anca.grosu@uniklinik-freiburg.de


Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. med. Anca-Ligia Grosu, Ärztliche Direktorin
  • Prof. Dr. med. Thomas Brunner, Geschäftsführender Oberarzt, Geschäftsführender Oberarzt
  • Prof. Dr. med. Michael Henke, Leiter Sektion Klinische Studien
  • Dr. med. Marianne Schmucker, Geschäftsführende Oberärztin
  • Prof. Dr. Dimos Baltas, Leiter der Abt. Medizinische Physik
  • Dr. med. Karl Henne, OA
  • Dr. medic/IM Temeschburg Carmen Martini, OÄ
  • Prof. Dr. med. Ursula Nestle
  • Dr. med. Henning Schäfer, OA
  • Dr. med. Jutta Scholber, OÄ
  • Dr. med. Sonja Adebahr
  • Nico Bartl
  • Dr. med. Angelika Bilger
  • Dr. med. Martin-Immanuel Bittner
  • Hatice Bunea
  • Dr. med./Univ. Andrei Bunea
  • Jamina Tara Fennell
  • Dr. med. Eleni Gkika
  • Dr. med. Emily Kim
  • Dr. med. Simon Kirste
  • Dr. med. Nicole Landenberger
  • Moritz Luttke, Assistenzarzt
  • Dr. med. Oliver Oehlke
  • Dr. med. Ilinca Popp
  • Nasr Salman
  • Daniel Schanne
  • Dr. med. Tanja Schimek-Jasch
  • Daniel Schnell
  • Lina Steffan, Assistenzärztin
  • Dr. med. Andreas Thomsen
  • Dr. /VAK Moskau Natascha Volegova-Neher
  • Dr. med. Nicole Wiedenmann
  • Dr. med. Constantinos Zamboglou
  • Amelia Cascajo Castresana
  • Dr. Maria Magdalena Fernandez Tomas
  • Dr. Mark Gainey
  • Dr. rer. nat. Michael Kollefrath
  • Dr. Kodor Koubar
  • Dipl. Phys. Sophie Küchler
  • Dr. Jördis Lübke
  • Dr. Sima Qamhiyeh
  • Dr. Ing. Thomas Rothe
  • Dr. rer. nat. Rolf Wiehle
  • Dr. med. Felix Heinemann, Leiter Klinische und Administrative Informatik
  • Prof. Dr. med. Gabriele Niedermann, Leiterin Sektion Strahlenbiologie
  • Dr. rer. nat. Elke Firat
  • Dr. Monika Gothwal
  • Michael Hettich
Einträge in der Rubrik "Who is Who"

Wissenschaftliche Projekte und Forschungsvorhaben


  • Assoziation zw. dem Schweregrad einer Mukositis, der Verängerung verschiedener Speichelparamteter und der zellulären Wundheilungspotenz währen sowie nach einer Strahlentherapie im Kopf-Hals-Bereich
  • CAO/ARO/AIO-12
  • CONKO-07
  • EMR100036-002 Eine offene Phase Ia / Ib-Studie mit dem DNA-PK-Inhibitor MSC2490484A in Kombination mit Strahlentherapie bei Patienten mit fortgeschrittenen soliden Tumoren
  • ESOPEC
  • F-MISO-PET
  • GLIAA - Aminosäure-PET versus MRT gesteuerte Re-Bestrahlung bei Patienten mit rezidiviertem Glioblastoma multiforme - eine randomisierte Phase II klinische Studie -
  • HERACLES
  • Hipporad MC-Studie
  • HNprädBio
  • L-AP-IS
  • L-AP-IS-Pilot
  • LARIS
  • LungArt
  • LungTech EORTC 22113-08113
  • PEACE 1
  • PEACE 2
  • PEGASUS
  • PET-Plan-Studie
  • PORTAF
  • SIP
  • STRIPE
  • Tumorspezifische Immunität und Inflammation beim Malignen Melanom
  • Verbundprojekt ZiSStrans: Zielstrukturen der individuellen Strahlenempfindlichkeit, Teilprojekt F

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Adeberg S, Bernhardt D, Harrabi SB, Nicolay NH, Horner-Rieber J, Konig L, Repka M, Mohr A, Abdollahi A, Weber KJ, Debus J, Rieken S: Metformin Enhanced in Vitro Radiosensitivity Associates with G2/M Cell Cycle Arrest and Elevated Adenosine-5'-monophosphate-activated Protein Kinase Levels in Glioblastoma. Radiol Oncol, 2017; 51 (4): 431-437. : http://dx.doi.org/10.1515/raon-2017-0042
  • Anagnostopoulos G, Andrassy M, Baltas D: The Bebig Valencia-type skin applicators: Dosimetric study and implementation of a dosimetric hybrid technique. Brachytherapy, 2017; 16 (5): 1044-1056. : http://dx.doi.org/10.1016/j.brachy.2017.04.243
  • Aselmaa A, van Herk M, Laprie A, Nestle U, Gotz I, Wiedenmann N, Schimek-Jasch T, Picaud F, Syrykh C, Cagetti LV, Jolnerovski M, Song Y, Goossens RH: Using a contextualized sensemaking model for interaction design: A case study of tumor contouring. J Biomed Inform, 2017; 65: 145-158. : http://dx.doi.org/10.1016/j.jbi.2016.12.001
  • Augustin NH, Kim SW, Uhlig A, Hanser C, Henke M, Schumacher M: A flexible multivariate random effects proportional odds model with application to adverse effects during radiation therapy. Biometrical J, 2017; 59: 1339-1351. : http://dx.doi.org/10.1002/bimj.201600142
  • Balermpas P, Rodel F, Krause M, Linge A, Lohaus F, Baumann M, Tinhofer I, Budach V, Sak A, Stuschke M, Gkika E, Grosu AL, Abdollahi A, Debus J, Stangl S, Ganswindt U, Belka C, Pigorsch S, Multhoff G, Combs SE, Welz S, Zips D, Lim SY, Rodel C, Fokas E: The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). Int J Cancer, 2017; 141 (3): 594-603. : http://dx.doi.org/10.1002/ijc.30770
  • Bell EH, Pugh SL, McElroy JP, Gilbert MR, Mehta M, Klimowicz AC, Magliocco A, Bredel M, Robe P, Grosu AL, Stupp R, Curran W Jr, Becker AP, Salavaggione AL, Barnholtz-Sloan JS, Aldape K, Blumenthal DT, Brown PD, Glass J, Souhami L, Lee RJ, Brachman D, Flickinger J, Won M, Chakravarti A: Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525. Jama-j Am Med Assoc, 2017; 3 (6): 784-792. : http://dx.doi.org/10.1001/jamaoncol.2016.6020
  • Bettinger D, Spode R, Glaser N, Buettner N, Boettler T, Neumann-Haefelin C, Brunner TB, Gkika E, Maruschke L, Thimme R, Schultheiss M: Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience. Bmc Gastroenterol, 2017; 17 (1) (online): 98-98. : http://dx.doi.org/10.1186/s12876-017-0656-z
  • Bilger A, Frenzel O, Oehlke O, Schmucker M, Wiehle R, Milanovic D, Nieder C, Grosu AL: Local control and overall survival after frameless LINAC radiosurgery: a single center experience Neuro-oncology, 2017; 19 (3): 105-106.
  • Carles M, Torres-Espallardo I, Alberich-Bayarri A, Olivas C, Bello P, Nestle U, Marti-Bonmati L: Evaluation of PET texture features with heterogeneous phantoms: complementarity and effect of motion and segmentation method. Phys Med Biol, 2017; 62 (2): 652-668. : http://dx.doi.org/10.1088/1361-6560/62/2/652
  • Champ CE, Ohri N, Klement RJ, Cantor M, Beriwal S, Glaser SM, Smith RP: Assessing Changes in the Activity Levels of Breast Cancer Patients During Radiation Therapy. Clin Breast Cancer, 2017. : http://dx.doi.org/10.1016/j.clbc.2017.08.009
  • Chatzikonstantinou G, Zamboglou N, Rodel C, Zoga E, Strouthos I, Butt SA, Tselis N: High-dose-rate brachytherapy as salvage modality for locally recurrent prostate cancer after definitive radiotherapy : A systematic review. Strahlenther Onkol, 2017; 193 (9): 683-691. : http://dx.doi.org/10.1007/s00066-017-1157-2
  • De Ruysscher D, Faivre-Finn C, Moeller D, Nestle U, Hurkmans CW, Le Pechoux C, Belderbos J, Guckenberger M, Senan S: European Organization for Research and Treatment of Cancer (EORTC) recommendations for planning and delivery of high-dose, high precision radiotherapy for lung cancer. Radiother Oncol, 2017; 124 (1): 1-10. : http://dx.doi.org/10.1016/j.radonc.2017.06.003
  • Fechter T, Adebahr S, Baltas D, Ben Ayed I, Desrosiers C, Dolz J: Esophagus segmentation in CT via 3D fully convolutional neural network and random walk. Med Phys, 2017; 44 (12): 6341-6352. : http://dx.doi.org/10.1002/mp.12593
  • Fink MK, Klement RJ: Diazoxide for Lowering Insulin Levels in Breast Cancer Patients. Oncologist, 2017; 22 (4): 491-491. : http://dx.doi.org/10.1634/theoncologist.2016-0402
  • Fricke A, Ullrich PV, Cimniak AFV, Becherer C, Follo M, Heinz J, Scholber J, Herget GW, Hauschild O, Wittel UA, Stark GB, Bannasch H, Braig D, Eisenhardt SU: Levels of activated platelet-derived microvesicles in patients with soft tissue sarcoma correlate with an increased risk of venous thromboembolism. Bmc Cancer, 2017; 17 (1) (online): 527. : http://dx.doi.org/10.1186/s12885-017-3515-y
  • Galldiks N, Albert NL, Sommerauer M, Grosu AL, Ganswindt U, Law I, Preusser M, Rhun EL, Vogelbaum MA, Zadeh G, Dhermain F, Weller M, Langen KJ, Tonn JC: PET imaging in patients with meningioma-report of the RANO/PET Group. Neuro-oncology, 2017; 19 (12): 1576-1587. : http://dx.doi.org/10.1093/neuonc/nox112
  • Gkika E, Adebahr S, Kirste S, Schimek-Jasch T, Wiehle R, Claus R, Wittel U, Nestle U, Baltas D, Grosu AL, Brunner TB: Stereotactic body radiotherapy (SBRT) in recurrent or oligometastatic pancreatic cancer : A toxicity review of simultaneous integrated protection (SIP) versus conventional SBRT. Strahlenther Onkol, 2017; 193 (6): 433-443. : http://dx.doi.org/10.1007/s00066-017-1099-8
  • Gkika E, Beitinger E, Adebahr S, Schimek-Jasch T, Wiesemann S, Waller C, Grosu AL, Nestle U, Kayser G: Prognostic significance of different immunohistochemical markers in small cell lung cancer Ann Oncol, 2017; 28 Suppl. 2: mdx090.011. : https://doi.org/10.1093/annonc/mdx090.011
  • Gkika E, Hallauer L, Kirste S, Adebahr S, Bartl N, Neeff HP, Fritsch R, Brass V, Nestle U, Grosu AL, Brunner TB: Stereotactic body radiotherapy (SBRT) for locally advanced intrahepatic and extrahepatic cholangiocarcinoma. Bmc Cancer, 2017; 17 (1): 781-781. : http://dx.doi.org/10.1186/s12885-017-3788-1
  • Gkika E, Hallauer L, Kirste S, Adebahr S, Bartl N, Neeff HP, Fritsch R, Brass V, Nestle U, Grosu AL, Brunner TB: Stereotactic body radiotherapy (SBRT) for locally advanced intrahepatic and extrahepatic cholangiocarcinoma. Bmc Cancer, 2017; 17 (1): 781-781. : http://dx.doi.org/10.1186/s12885-017-3788-1
  • Gkika E, Schultheiss M, Bettinger D, Maruschke L, Neeff HP, Schulenburg M, Adebahr S, Kirste S, Nestle U, Thimme R, Grosu AL, Brunner TB: Excellent local control and tolerance profile after stereotactic body radiotherapy of advanced hepatocellular carcinoma. Radiat Oncol, 2017; 12 (1) (online): 116-116. : http://dx.doi.org/10.1186/s13014-017-0851-7
  • Gkika E, Tanadini-Lang S, Kirste S, Holzner PA, Neeff HP, Rischke HC, Reese T, Lohaus F, Duma MN, Dieckmann K, Semrau R, Stockinger M, Imhoff D, Kremers N, Hafner MF, Andratschke N, Nestle U, Grosu AL, Guckenberger M, Brunner TB: Interobserver variability in target volume delineation of hepatocellular carcinoma : An analysis of the working group "Stereotactic Radiotherapy" of the German Society for Radiation Oncology (DEGRO). Strahlenther Onkol, 2017; 193 (10): 823-830. : http://dx.doi.org/10.1007/s00066-017-1177-y
  • Gkika E, Vach W, Adebahr S, Schimeck-Jasch T, Brenner A, Brunner TB, Kaier K, Prasse A, Muller-Quernheim J, Grosu AL, Zissel G, Nestle U: Is serum level of CC chemokine ligand 18 a biomarker for the prediction of radiation induced lung toxicity (RILT)? Plos One, 2017; 12 (9) (online): e0185350. : http://dx.doi.org/10.1371/journal.pone.0185350
  • Hatt M, Lee JA, Schmidtlein CR, Naqa IE, Caldwell C, De Bernardi E, Lu W, Das S, Geets X, Gregoire V, Jeraj R, MacManus MP, Mawlawi OR, Nestle U, Pugachev AB, Schoder H, Shepherd T, Spezi E, Visvikis D, Zaidi H, Kirov AS: Classification and evaluation strategies of auto-segmentation approaches for PET: Report of AAPM task group No. 211. Med Phys, 2017; 44 (6): e1-e42. : http://dx.doi.org/10.1002/mp.12124
  • Jilg CA, Drendel V, Rischke HC, Beck T, Vach W, Schaal K, Wetterauer U, Schultze-Seemann W, Meyer PT: Diagnostic Accuracy of Ga-68-HBED-CC-PSMA-Ligand-PET/CT before Salvage Lymph Node Dissection for Recurrent Prostate Cancer. Theranostics, 2017; 7 (6): 1770-1780. : http://dx.doi.org/10.7150/thno.18421
  • Klein Geltink RI, O'Sullivan D, Corrado M, Bremser A, Buck MD, Buescher JM, Firat E, Zhu X, Niedermann G, Caputa G, Kelly B, Warthorst U, Rensing-Ehl A, Kyle RL, Vandersarren L, Curtis JD, Patterson AE, Lawless S, Grzes K, Qiu J, Sanin DE, Kretz O, Huber TB, Janssens S, Lambrecht BN, Rambold AS, Pearce EJ, Pearce EL: Mitochondrial Priming by CD28. Cell, 2017; 171 (2): 385-397.e11. : http://dx.doi.org/10.1016/j.cell.2017.08.018
  • Klement RJ, Guckenberger M, Alheid H, Allgauer M, Becker G, Blanck O, Boda-Heggemann J, Brunner T, Duma M, Gerum S, Habermehl D, Hildebrandt G, Lewitzki V, Ostheimer C, Papachristofilou A, Petersen C, Schneider T, Semrau R, Wachter S, Andratschke N: Stereotactic body radiotherapy for oligo-metastatic liver disease - Influence of pre-treatment chemotherapy and histology on local tumor control. Radiother Oncol, 2017; 123 (2): 227-233. : http://dx.doi.org/10.1016/j.radonc.2017.01.013
  • Linge A, Schotz U, Lock S, Lohaus F, von Neubeck C, Gudziol V, Nowak A, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rodel C, Bunea H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Lauber K, Pigorsch S, Combs SE, Monnich D, Zips D, Baretton GB, Buchholz F, Krause M, Belka C, Baumann M: Comparison of detection methods for HPV status as a prognostic marker for Radiother Oncol, 2017. : http://dx.doi.org/10.1016/j.radonc.2017.12.007
  • MacManus M, Everitt S, Schimek-Jasch T, Li XA, Nestle U, Kong FS: Anatomic, functional and molecular imaging in lung cancer precision radiation therapy: treatment response assessment and radiation therapy personalization. Translational Lung Cancer Research, 2017; 6 (6): 670-688. : http://dx.doi.org/10.21037/tlcr.2017.09.05
  • Mavroidis P, Komisopoulos G, Buckey C, Mavroeidi M, Swanson GP, Baltas D, Papanikolaou N, Stathakis S: Radiobiological evaluation of prostate cancer IMRT and conformal-RT plans using different treatment protocols. Phys Medica, 2017; 40: 33-41. : http://dx.doi.org/10.1016/j.ejmp.2017.07.003
  • Moustakis C, Blanck O, Ebrahimi F, Ka Heng Chan M, Ernst I, Krieger T, Duma MN, Oechsner M, Ganswindt U, Heinz C, Alheit H, Blank H, Nestle U, Wiehle R, Kornhuber C, Ostheimer C, Petersen C, Pollul G, Baus W, Altenstein G, Beckers E, Jurianz K, Sterzing F, Kretschmer M, Seegenschmiedt H, Maass T, Droege S, Wolf U, Schoeffler J, Haverkamp U, Eich H, Guckenberger M: Time for standardization of SBRT planning through large scale clinical data and guideline-based approaches. Strahlenther Onkol, 2017; 193 (12): 1068-1069. : http://dx.doi.org/10.1007/s00066-017-1216-8
  • Moustakis C, Blanck O, Ebrahimi Tazehmahalleh F, Ka Heng Chan M, Ernst I, Krieger T, Duma MN, Oechsner M, Ganswindt U, Heinz C, Alheit H, Blank H, Nestle U, Wiehle R, Kornhuber C, Ostheimer C, Petersen C, Pollul G, Baus W, Altenstein G, Beckers E, Jurianz K, Sterzing F, Kretschmer M, Seegenschmiedt H, Maass T, Droege S, Wolf U, Schoeffler J, Haverkamp U, Eich HT, Guckenberger M: Planning benchmark study for SBRT of early stage NSCLC : Results of the DEGRO Working Group Stereotactic Radiotherapy. Strahlenther Onkol, 2017; 193 (10): 780-790. : http://dx.doi.org/10.1007/s00066-017-1151-8
  • Nieder C, Hintz M, Oehlke O, Bilger A, Grosu AL: Validation of the graded prognostic assessment for lung cancer with brain metastases using molecular markers (lung-molGPA). Radiat Oncol, 2017; 12 (1): 107-107. : http://dx.doi.org/10.1186/s13014-017-0844-6
  • Nieder C, Hintz M, Oehlke O, Bilger A, Grosu AL: The TNM 8 M1b and M1c classification for non-small cell lung cancer in a cohort of patients with brain metastases. Clin Transl Oncol, 2017; 19 (9): 1141-1146. : http://dx.doi.org/10.1007/s12094-017-1651-0
  • Nieder C, Norum J, Hintz M, Grosu AL: Short Survival Time after Palliative whole Brain Radiotherapy: Can We Predict Potential Overtreatment by Use of a Nomogram? J Cancer, 2017; 8 (9): 1525-1529. : http://dx.doi.org/10.7150/jca.18600
  • Perry JR, Laperriere N, O'Callaghan CJ, Brandes AA, Menten J, Phillips C, Fay M, Nishikawa R, Cairncross JG, Roa W, Osoba D, Rossiter JP, Sahgal A, Hirte H, Laigle-Donadey F, Franceschi E, Chinot O, Golfinopoulos V, Fariselli L, Wick A, Feuvret L, Back M, Tills M, Winch C, Baumert BG, Wick W, Ding K, Mason WP, Mulroy LA, NAZ F, Mathieu D, Vincent F, Kavan P, Masucci GL, Chung C, Macdonald DR, Pitz MW, Easaw J, Mckenzie M, Agranovich AL, Pai HH, Meijnder P, Bouttens F, Eekers D, Truc G, van den Bent MJ, Gijtenbeek J, Niel C, Kortmann R-D, Hanse M, Wiggenraad RGJ, Kantor G, Enting R, Steinbach J, Baurain j-F, Weytjens R, Reeni M, Bolla M, De Jong M, Fabbro M, Grosu A, Bozec L, Tabatabai G, Servagi-Vernat S, Chapman R, Dally M, Fay M, Foote M, Ludbrook J, Hill J, Potter A, Skala M, Joseph D, James M, Yamasaki F: Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma. New Engl J Med, 2017; 376 (11): 1027-1037. : http://dx.doi.org/10.1056/NEJMoa1611977
  • Ramkumar A, Stappers PJ, Niessen WJ, Adebahr S, Schimek-Jasch T, Nestle U/Song Y: Using GOMS and NASA-TLX to evaluate human-computer interaction process in interactive segmentation International Journal of Human-computer Interaction, 2017; 33 (2): 123-134.
  • Rieber J, Abbassi-Senger N, Adebahr S, Andratschke N, Blanck O, Duma M, Eble MJ, Ernst I, Flentje M, Gerum S, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass ND, Krempien R, Lohaus F, Lohr F, Petersen C, Schrade E, Streblow J, Uhlmann L, Wittig A, Sterzing F, Guckenberger M: Influence of Institutional Experience and Technological Advances on Outcome of Stereotactic Body Radiation Therapy for Oligometastatic Lung Disease. Int J Radiat Oncol, 2017; 98 (3): 511-520. : http://dx.doi.org/10.1016/j.ijrobp.2016.09.026
  • Schiller F, Fechter T, Zamboglou C, Chirindel A, Salman N, Jilg CA, Drendel V, Werner M, Meyer PT, Grosu AL, Mix M: Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation. EJNMMI Phys, 2017; 4 (1) (online): 21. : http://dx.doi.org/10.1186/s40658-017-0188-1
  • Schlachter M, Fechter T, Adebahr S, Schimek-Jasch T, Nestle U, Buhler K: Visualization of 4D multimodal imaging data and its applications in radiotherapy planning. J Appl Clin Med Phys, 2017; 18 (6): 183-193. : http://dx.doi.org/10.1002/acm2.12209
  • Strouthos I, Chatzikonstantinou G, Tselis N, Bon D, Karagiannis E, Zoga E, Ferentinos K, Maximenko J, Nikolettou-Fischer V, Zamboglou N: Photobiomodulation therapy for the management of radiation-induced dermatitis : A single-institution experience of adjuvant radiotherapy in breast cancer patients after breast conserving surgery. Strahlenther Onkol, 2017; 193 (6): 491-498. : http://dx.doi.org/10.1007/s00066-017-1117-x
  • Tanadini-Lang S, Rieber J, Filippi AR, Fode MM, Streblow J, Adebahr S, Andratschke N, Blanck O, Boda-Heggemann J, Duma M, Eble MJ, Ernst I, Flentje M, Gerum S, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass ND, Krempien R, Lohaus F, Petersen C, Schrade E, Wendt TG, Wittig A, Hoyer M, Ricardi U, Sterzing F, Guckenberger M: Nomogram based overall survival prediction in stereotactic body radiotherapy for oligo-metastatic lung disease. Radiother Oncol, 2017; 123 (2): 182-188. : http://dx.doi.org/10.1016/j.radonc.2017.01.003
  • Tselis N, Hoskin P, Baltas D, Strnad V, Zamboglou N, Rodel C, Chatzikonstantinou G: High Dose Rate Brachytherapy as Monotherapy for Localised Prostate Cancer: Review of the Current Status. Clin Oncol-uk, 2017; 29 (7): 401-411. : http://dx.doi.org/10.1016/j.clon.2017.02.015
  • Wieser G, Popp I, Christian Rischke H, Drendel V, Grosu AL, Bartholoma M, Weber WA, Mansi R, Wetterauer U, Schultze-Seemann W, Meyer PT, Jilg CA: Diagnosis of recurrent prostate cancer with PET/CT imaging using the gastrin-releasing peptide receptor antagonist 68Ga-RM2: Preliminary results in patients with negative or inconclusive [18F]Fluoroethylcholine-PET/CT. Eur J Nucl Med Mol I, 2017; 44 (9): 1463-1472. : http://dx.doi.org/10.1007/s00259-017-3702-8
  • Wilson JM, Mukherjee S, Brunner TB, Partridge M, Hawkins MA: Correlation of 18F-Fluorodeoxyglucose Positron Emission Tomography Parameters with Patterns of Disease Progression in Locally Advanced Pancreatic Cancer after Definitive Chemoradiotherapy. Clin Oncol-uk, 2017; 29 (6): 370-377. : http://dx.doi.org/10.1016/j.clon.2017.01.038
  • Zamboglou C, Drendel V, Jilg AC, Rischke HC, Beck TI, Schultze-Seemann W, Krauss T, Mix M, Schiller F, Wetterauer U, Werner M, Langer M, Bock M, Meyer PT, Grosu AL: Comparison of 68 Ga-HBED-CC PSMA-PET/CT and multiparametric MRI for gross tumour volume detection in patients with primary prostate cancer based on slice by slice comparison with histopathology Theranostics, 2017; 7 (1): 228-237.
  • Zamboglou C, Sachpazidis I, Koubar K, Drendel V, Wiehle R, Kirste S, Mix M, Schiller F, Mavroidis P, Meyer PT, Werner M, Grosu AL, Baltas D: Evaluation of intensity modulated radiation therapy dose painting for localized prostate cancer using 68Ga-HBED-CC PSMA-PET/CT: A planning study based on histopathology reference. Radiother Oncol, 2017; 123 (3): 472-477. : http://dx.doi.org/10.1016/j.radonc.2017.04.021
Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften:
  • Allam A, Thomsen AR, Gothwal M, Saha D, Maurer J, Brunner TB: Pancreatic stellate cells in pancreatic cancer: In focus. Pancreatology, 2017; 17 (4): 514-522. : http://dx.doi.org/10.1016/j.pan.2017.05.390
  • Fennell J, Wiedenmann N, Oehlke O, Kraft J, Grosu AL: Hypoxia and positron emission tomography in patients with gliomas Clinical Transl Imaging, 2017; 5: 447-453.
  • Nieder C, Langendijk JA, Guckenberger M, Grosu AL: Preserving the legacy of reirradiation: A narrative review of historical publications. Adv Radiat Oncol, 2017; 2 (2): 176-182. : http://dx.doi.org/10.1016/j.adro.2017.02.005
  • Oehlke O, Grosu AL: PET/MRI and brain tumors: focus on radiation oncology treatment planning Clinical Transl Imaging, 2017; 5: 159-167.
Buchbeiträge:
  • Berger P, Mertelsmann R, Baltas B, Brunner TB, Grosu AL, Henke M, Henne K, Schaefer H, Niedermann G, et al: Das Rote Buch - Hämatologie und Internistische Onkologie In: D. P. Berger; R. Mertelsmann (Hrsg.): Das Rote Buch, 6. Auflage. ecomed Medizin, 2017.
  • Engelhardt M, Berger DP, Mertelsmann R, Duyster J, Grosu AL, et al: Das Blaue Buch - Chemotherapie-Manual Hämatologie und Onkologie In: Das Blaue Buch, 6. Auflage. Springer, 2017.
  • Hufschmidt A, Rauer S, Glocker FX, Grosu AL, et al: Neurologie Compact für Klinik und Praxis In: Neurologie Compact, 7. Auflage. Georg Thieme Verlag, 2017.
  • Schanne H, Grosu A, Duda D: Anti-angiogenics and Radiation Therapy In: Tumor Angiogenesis: A Key Target for Cancer Therapy Berlin: Springer, 2017. (in Druck)

Besondere wissenschaftliche Aktivitäten

Stipendien:
  • Montserrat Carles: Forschungsstipendium - Universitätsklinik La Fe; Valencia/Spanien, 01.07.2015 bis 30.06.2017.
Vorsitze und Sprechertätigkeiten:
  • Prof. Dr. med. Anca-L.Grosu, Heinemann F, Röhner F, Schmucker M: Elektronische Krankenakte in der Strahlenheilkunde, DEGRO Ausschuss, seit 09.07.2009.
  • Prof. Dr. med. Anca-L. Grosu: Vorstandsvorsitzende der Hanns-Langendorf-Stiftung, seit 2010.
  • Prof. Dr. med. Anca-Ligia Grosu: Vorstandsmitglied der Deutschen Neuroonkologischen Arbeitsgruppe (NOA), seit 2011.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied des unabhängigen Expertengremiums der Deutschen Gesellschaft für Radioonkologie (DEGRO), seit 2011.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied der Arbeitsgemeinschaft Radiologische Onkologie (ARO), seit 2011.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied des Geschäftsführenden Vorstands des Comprehensive Cancer Centers, Universitätsklinikum Freiburg (CCCF), seit 2012.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied im Beirat des Comprehensive Cancer Centers Graz (CCC Graz), Österreich, seit 2014.
  • Prof. Dr. med. Anca-Ligia Grosu: Stellvertretende Vorsitzende des Deutschen Konsortiums für Translationale Krebsmedizin, Universitätsklinikum Freiburg (DKTK Partnerstandort Freiburg) , seit 2015.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied im Senat der Albert-Ludwigs-Universität Freiburg , seit 2015.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied der Redaktionsleitung der Fachzeitschrift "Radiotherapy and Oncology" (The Green Journal), seit 2015.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied der Redaktion der Fachzeitschrift "Strahlentherapie und Onkologie", seit 2016.
  • Prof. Dr. med. Anca-Ligia Grosu: Mitglied der Redaktionsleitung der Fachzeitschrift "Physics and Imaging in Radiation Oncology", seit 01.08.2016.
  • Prof. Dr. med. Ursula Nestle: Vorsitzende des Ausschusses "Strahlenschutz in der Medizin" Strahlenschutzkommission , seit 2015.

Abschlussarbeiten