Department für Radiologische Diagnostik und Therapie

Klinik für Strahlenheilkunde

Robert Koch Str. 3
79106 Freiburg
Tel: 0049-761-270-9461 Fax: 0049-761-270-9472
Email anca.grosu@uniklinik-freiburg.de



Wissenschaftliche Mitarbeiterinnen und Mitarbeiter

  • Prof. Dr. Dr. h.c. Hermann Frommhold, Ärztlicher Direktor
  • Prof. Dr. med. Johannes Lutterbach, Ltd. Oberarzt
  • Dr. med. Annette Barke
  • Dr. med. Susanne Bartelt
  • Prof. Dr. med. Michael Henke, Leiter Sektion Klinische Studien
  • Dr. med. Marianne Schmucker, Geschäftsführende Oberärztin
  • Dr. med. Christian Weißenberger
  • Dr. med. Karl Henne, OA
  • Dr. med. Stephan Hennings
  • Dr. medic/IM Temeschburg Carmen Martini, OÄ
  • Dr. med. Birgit Opferkuch
  • Dr. med. Jutta Scholber, OÄ
  • Dr. rer.nat. Siegfried Stange
  • Dr. med. Inge Uhlig, OÄ
  • Dr. med. Christina Hanser
  • Dr. med. Eva Lewandowski
  • Dr. med. Christine Müller, wissenschaft. Mitarbeiterin
  • Dr. med. Tanja Schimek-Jasch
  • Dr. med. Petra Stegmaier
  • Dr. /VAK Moskau Natascha Volegova-Neher
  • Dr. rer.nat. Gregor Bruggmoser, Leitender Physiker
  • Dr. rer. nat. Ahmed Nil
  • Dr. rer. nat. Norbert Hodapp
  • Dr. rer. nat. Jisen Huai
  • Dipl. Phys. Sophie Küchler
  • Dr. rer. nat. Fred Röhner
  • Dr. rer. nat. Rolf Wiehle
  • Dr. med. Felix Heinemann, Leiter Klinische und Administrative Informatik
  • Sonja Adebahr, Assistenzärztin
  • Prof. Dr. med. Gabriele Niedermann, Leiterin Sektion Strahlenbiologie
  • Tanja Schimeck-Jasch, Assistenzärztin
  • Dr. rer. nat. Elke Firat
Einträge in der Rubrik "Who is Who"

Finanzierung

  • Lutterbach J: Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg (AZ 7851)

Wissenschaftliche Projekte und Forschungsvorhaben


  • Charakterisierung von TPPII-Knockout-Mäusen und Mäusen mit kombinierter Ablation von TPPII und ERAP1
  • Elucidation of the functions of TPPII in conditional TPPII knockout mice
  • Induzierbare Immundefizienz mittels HIF-1-Nef. Teilprojekt B4, SFB 620
  • Oncocase - Verbundpilotprojekt internetbasiertes multimediales Lehr-/Lern- und Evaluationsprogramm in Verbindung mit konventionellem Präsenzstudium in Kleingruppen

Wissenschaftliche Publikationen

Originalarbeiten in wissenschaftlichen Fachzeitschriften:
  • Akpek S, Brunner T, Benndorf G, Strother C: Three-dimensional imaging and cone beam volume CT in C-arm angiography with flat panel detector. Diagn Interv Radiol, 2005; 11 (1): 10-13.
  • Becker G,, Momm F,, Schwacha H,, Hodapp N,, Usadel H,, Geissler M,, Barke A,, Schmitt-Graff A,, Henne K,, Blum HE: Klatskin tumor treated by inter-disciplinary therapies including stereotactic radiotherapy: a case report. World Journal of Gastroentero, 2005; 11 (31): 4923-4926.
  • Brunner TB, Cengel KA, Hahn SM, Wu J, Fraker DL, McKenna WG, Bernhard EJ: Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras. Cancer Res, 2005; 65 (18): 8433-8441. : http://dx.doi.org/10.1158/0008-5472.CAN-05-0158
  • Brunner TB, Merkel S, Grabenbauer GG, Meyer T, Baum U, Papadopoulos T, Sauer R, Hohenberger W: Definition of elective lymphatic target volume in ductal carcinoma of the pancreatic head based on histopathologic analysis. Int J Radiat Oncol, 2005; 62 (4): 1021-1029. : http://dx.doi.org/10.1016/j.ijrobp.2004.12.018
  • Gannage M,, Abel M,, Michallet AS,, Delluc S,, Lambert M,, Giraudier S,, Kratzer R,, Niedermann G,, Saveanu L,, Guilhot F,, Camoin L,, Varet B,, Buzyn A,, Caillat-Zucman S: Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy. J Immunol, 2005; 174 (12): 8210-8218.
  • Geisse S, Henke M: Large-scale transient transfection of mammalian cells: a newly emerging attractive option for recombinant protein production. Journal of Structural & Functional Genomics , 2005; 6 (2-3): 165-170.
  • Hassainya Y,, Kratzer R, Pons-Garcia F, Lindo V, Greer F, Lemonnier F, Niedermann G, van Endert PM: Identification of naturally processed HLA-A2 restricted proinsulin epitopes by reverse immunology Diabetes, 2005; 54: 2053-2059.
  • Henke M: Erythropoietin in the Treatment of Cancer Onkologie, 2005; 28: 181-182.
  • Klenzner T, Knapp F, Rohner F, von Wallenberg E, Mauch H, Pedersen P, Aschendorff A, Laszig R, Lutterbach J: Influence of ionizing radiation on nucleus 24 cochlear implants. Otol Neurotol, 2005; 26 (4): 661-667.
  • Limbach LK, Li Y, Grass RN, Brunner TJ, Hintermann MA, Muller M, Gunther D, Stark WJ: Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations. Environ Sci Technol, 2005; 39 (23): 9370-9376.
  • Lutterbach J, Ostertag C: What is the appropriate radiotherapy protocol for older patients with newly diagnosed glioblastoma? J Clin Oncol, 2005; 23 (12): 2869-2870.
  • Lutterbach J, Pagenstecher A, Spreer J, Hetzel A, Velthoven V, Nikkhah G, Frommhold H, Volk B, Schumacher M, Lucking C, Zentner J, Ostertag C: The brain tumor board: lessons to be learned from an interdisciplinary conference Onkologie, 2005; 28: 22-26.
  • Lutterbach J, Pagenstecher A, Weyerbrock A, Schultze-Seemann W, Waller CF: Early-stage penile carcinoma metastasizing to brain: case report and literature review. Urology, 2005; 66 (2): 432-433.
  • Lutterbach J, Bartelt S, Momm F, Becker G, Frommhold H, Ostertag C: Is older age associated with a worse prognosis due to different patterns of care? A long-term study of 1346 patients with glioblastomas or brain metastases. Cancer, 2005; 103 (6): 1234-1244.
  • Momm F, Bartels S, Haigis K, Grosse-Sender A, Witucki G: Spectrophotometric skin measurements correlate with EORTC/RTOG-common toxicity criteria Strahlenther Onkol, 2005; 181 (6): 392-395.
  • Momm F, Lutterbach J: Postradiotherapy quality of life for head-and-neck cancer patients is independent of xerostomia: in regard to Ringash et al. Int J Radiat Oncol, 2005; 63 (3): 969-70.
  • Momm F, Volegova-Neher NJ, Schulte-Monting F, Guttenberger R: Different saliva substitutes for treatment of xerostomia following radiotherapy. A prospective crossover study. Strahlenther Onkol, 2005; 181 (4): 231-236.
  • Pajonk F, van Ophoven A, Weissenberger C, McBride WH: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism. Bmc Cancer, 2005; 5 (1): 76.
  • Saveanu L,, Carroll O,, Lindo V,, del Val M,, Lopez D,, Lepelletier Y,, Greer F,, Schomburg L,, Fruci D,, Niedermann G,, van Endert PM: Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat Immunol, 2005; 6: 689-697.
  • van Beilen JB, Smits TH, Roos FF, Brunner T, Balada SB, Rothlisberger M, Witholt B: Identification of an amino acid position that determines the substrate range of integral membrane alkane hydroxylases. J Bacteriol, 2005; 187 (1): 85-91. : http://dx.doi.org/10.1128/JB.187.1.85-91.2005
  • Wasserman TH, Brizel DM, Henke M, Monnier A, Eschwege F, Sauer R, Strnad V: Influence of intravenous amifostine on xerostomia, tumor control, and survival after radiotherapy for head-and- neck cancer: 2-year follow-up of a prospective, randomized, phase III trial. Int J Radiat Oncol, 2005; 63 (4): 985-990.
  • Yada S, Takamura N, Inagaki-Ohara K, O'leary MK, Wasem C, Brunner T, Green DR, Lin T, Pinkoski MJ: The role of p53 and Fas in a model of acute murine graft-versus-host disease. J Immunol, 2005; 174 (3): 1291-1297.
Konferenzbeiträge:
  • Weissenberger C, Geißler M, Otto B, Barke A, Henne K, von Plehn A, Rein A, Müller M, Henke M: Anemia and long-term outcome in adjuvant radiochemotherapy of stage II and III rectal adenocarcinoma. The Freiburg Experience (1989 - 2002) Anticancer Res, 2005; 25 (6D): 4778-4779.
  • Weissenberger C, Witucki G: Psychosocial factors of cancer patients and use of the internet as source of oncological information. Strahlenther Onkol, 2005; 181 (75).

Besondere wissenschaftliche Aktivitäten

Abschlussarbeiten

Habilitationen
  • Momm F: Nebenwirkungen der Strahlentherapie. Prognostische Faktoren - Auswirkungen - Behandlungsmöglichkeiten, 2005.
Promotionen
  • Müller Bastian: Die primär definitive Strahlentherapie von Kopf-Hals-Tumoren (Erstgutachter/in Prof. Dr. med. Michael Henke, Zweitgutachter/in Prof. Dr. med. Jörg Schipper), 2005.
  • Sturzenhecker Henner: Quantitativer und semiquantitativer Nachweis von Erythropoetin-vermittelten Signalintensitätsänderungen in der Magnetresonanz-Tomographie des Femurs bei Patienten mit Tumoranämie (Erstgutachter/in Prof. Dr. med. Michael Langer, Zweitgutachter/in Prof. Dr. med. Michael Henke), 2005.